MCID: MXL002
MIFTS: 22

Maxillary Sinus Adenoid Cystic Carcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Maxillary Sinus Adenoid Cystic Carcinoma

MalaCards integrated aliases for Maxillary Sinus Adenoid Cystic Carcinoma:

Name: Maxillary Sinus Adenoid Cystic Carcinoma 12 15 17 70
Adenoid Cystic Carcinoma of the Maxillary Sinus 12
Adenoid Cystic Carcinoma of Maxillary Sinus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7198
NCIt 50 C6239
UMLS 70 C1334643

Summaries for Maxillary Sinus Adenoid Cystic Carcinoma

MalaCards based summary : Maxillary Sinus Adenoid Cystic Carcinoma, also known as adenoid cystic carcinoma of the maxillary sinus, is related to adenoid cystic carcinoma and spastic paraplegia, intellectual disability, nystagmus, and obesity, and has symptoms including pain and rhinorrhea. An important gene associated with Maxillary Sinus Adenoid Cystic Carcinoma is NUMB (NUMB Endocytic Adaptor Protein), and among its related pathways/superpathways are Allograft rejection and Immune response Role of DAP12 receptors in NK cells. Affiliated tissues include salivary gland and prostate, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Maxillary Sinus Adenoid Cystic Carcinoma

Diseases related to Maxillary Sinus Adenoid Cystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 adenoid cystic carcinoma 10.4
2 spastic paraplegia, intellectual disability, nystagmus, and obesity 10.2
3 dental abscess 10.2
4 chronic apical periodontitis 10.2
5 periodontitis 10.2
6 lung cancer susceptibility 3 10.2
7 mucositis 10.2
8 neutropenia 10.2
9 adenocarcinoma 10.2
10 mature t-cell and nk-cell lymphoma 9.9 KIR3DL2 IL2
11 sezary's disease 9.8 KIR3DL2 IL2
12 vogt-koyanagi-harada disease 9.8 KIR3DL3 KIR3DL2
13 melanoma, uveal 9.8 NUMB IL2
14 mycosis fungoides 9.8 KIR3DL2 IL2
15 nk cell deficiency 9.7 KLRC2 IL2
16 celiac disease 1 9.5 KLRC2 IL2

Graphical network of the top 20 diseases related to Maxillary Sinus Adenoid Cystic Carcinoma:



Diseases related to Maxillary Sinus Adenoid Cystic Carcinoma

Symptoms & Phenotypes for Maxillary Sinus Adenoid Cystic Carcinoma

UMLS symptoms related to Maxillary Sinus Adenoid Cystic Carcinoma:


pain; rhinorrhea

GenomeRNAi Phenotypes related to Maxillary Sinus Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

26 (show all 27)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-1 10.14 NUMB
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-102 10.14 KIR3DL3
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 10.14 KLRC2
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-107 10.14 KLRC2
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-119 10.14 KIR3DL3
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-125 10.14 KIR3DL2
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 10.14 KIR3DL3
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-147 10.14 KLRC2
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-152 10.14 KIR3DL3 KLRC2
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 10.14 KLRC2
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-179 10.14 KLRC2
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-185 10.14 NUMB
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-190 10.14 KIR3DL3
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-195 10.14 KIR3DL2
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-202 10.14 KIR3DL3
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-207 10.14 KLRC2
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-211 10.14 KIR3DL3
18 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 10.14 KIR3DL3 KLRC2 NUMB
19 Decreased shRNA abundance (Z-score < -2) GR00366-A-23 10.14 KLRC2
20 Decreased shRNA abundance (Z-score < -2) GR00366-A-30 10.14 KLRC2
21 Decreased shRNA abundance (Z-score < -2) GR00366-A-31 10.14 KIR3DL3
22 Decreased shRNA abundance (Z-score < -2) GR00366-A-48 10.14 KLRC2
23 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 10.14 KLRC2
24 Decreased shRNA abundance (Z-score < -2) GR00366-A-73 10.14 KIR3DL3
25 Decreased shRNA abundance (Z-score < -2) GR00366-A-79 10.14 KIR3DL3
26 Decreased shRNA abundance (Z-score < -2) GR00366-A-82 10.14 KLRC2
27 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 10.14 KIR3DL2

Drugs & Therapeutics for Maxillary Sinus Adenoid Cystic Carcinoma

Search Clinical Trials , NIH Clinical Center for Maxillary Sinus Adenoid Cystic Carcinoma

Genetic Tests for Maxillary Sinus Adenoid Cystic Carcinoma

Anatomical Context for Maxillary Sinus Adenoid Cystic Carcinoma

MalaCards organs/tissues related to Maxillary Sinus Adenoid Cystic Carcinoma:

40
Salivary Gland, Prostate

Publications for Maxillary Sinus Adenoid Cystic Carcinoma

Articles related to Maxillary Sinus Adenoid Cystic Carcinoma:

(show all 22)
# Title Authors PMID Year
1
Advanced adenoid cystic carcinoma of maxillary sinus: Rare case report and review of literature. 61
33592415 2021
2
Adenoid Cystic Carcinoma of the Maxillary Sinus with Isolated Trigeminal Anesthesia. 61
30005538 2018
3
Uptake of Prostate-Specific Membrane Antigen (PSMA) in adenoid cystic carcinoma - Is PSMA-PET-CT a helpful tool in radiation oncology? 61
29594233 2017
4
Numb chin with mandibular pain or masticatory weakness as indicator for systemic malignancy - A case series study. 61
28728749 2017
5
Adult cancer-related hemophagocytic lymphohistiocytosis - a challenging diagnosis: a case report. 61
28651636 2017
6
Adenoid cystic carcinoma of the maxillary sinus: a clinical-pathological report of 10 years of experience from a single institution. 61
25088528 2014
7
Adenoid cystic carcinoma of the maxillary sinus: CT and MR imaging findings. 61
24057204 2013
8
Chemoradiotherapy for maxillary sinus adenoid cystic carcinoma using superselective intra-arterial infusion via a superficial temporal artery. 61
21953943 2013
9
A rare case of metachronous triple cancers involving the tympanic membrane. 61
24353544 2013
10
Unusual spinal metastases from an adenoid cystic carcinoma of the maxillary sinus. 61
22321367 2012
11
Tumor-to-tumor metastasis: maxillary sinus adenoid cystic carcinoma metastasizing to double primary lung adenocarcinoma. 61
20868783 2010
12
[Clinical study of 36 cases with adenoid cystic carcinoma of the maxillary sinus]. 61
18357710 2008
13
Retrobulbar alcohol injection for orbital pain relief under difficult circumstances: a case report. 61
16710497 2006
14
Adenoid cystic carcinoma of the maxillary sinus with gradual histologic transformation to high-grade adenocarcinoma: a comparative report with dedifferentiated carcinoma. 61
16133359 2006
15
[Endoscopic or endoscope-assisted surgery for sinonasal malignancy]. 61
15605998 2004
16
Fractionated stereotactic radiation therapy for extracranial head and neck tumors. 61
10974468 2000
17
Adenoid cystic carcinoma of the maxillary sinus. 61
9368440 1997
18
[Differentiation therapy for salivary gland tumors]. 61
7685583 1993
19
Induction of bone formation in an adenoid cystic carcinoma of the maxillary sinus by adoptive immunotherapy involving intra-arterial injection of lymphokine-activated killer cells and recombinant interleukin-2 in combination with radiotherapy. 61
2166140 1990
20
Adenoid cystic carcinoma of the maxillary sinus. 61
2855449 1988
21
Adenoid cystic carcinoma of the maxillary sinus. 61
178803 1976
22
[Case of adenoid cystic carcinoma of the maxillary sinus]. 61
5625747 1967

Variations for Maxillary Sinus Adenoid Cystic Carcinoma

Expression for Maxillary Sinus Adenoid Cystic Carcinoma

Search GEO for disease gene expression data for Maxillary Sinus Adenoid Cystic Carcinoma.

Pathways for Maxillary Sinus Adenoid Cystic Carcinoma

Pathways related to Maxillary Sinus Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12 KLRC2 KIR3DL3 KIR3DL2 IL2
2
Show member pathways
11.4 KLRC2 KIR3DL3 KIR3DL2 IL2
3 11.22 KLRC2 IL2

GO Terms for Maxillary Sinus Adenoid Cystic Carcinoma

Biological processes related to Maxillary Sinus Adenoid Cystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular defense response GO:0006968 8.62 KLRC2 KIR3DL2

Sources for Maxillary Sinus Adenoid Cystic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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