MCID: MYT019
MIFTS: 25

May-Thurner Syndrome

Categories: Blood diseases, Cardiovascular diseases, Rare diseases

Aliases & Classifications for May-Thurner Syndrome

MalaCards integrated aliases for May-Thurner Syndrome:

Name: May-Thurner Syndrome 20 70
Iliac Vein Compression Syndrome 20
Iliocaval Compression Syndrome 20
May Thurner Syndrome 20
Cockett Syndrome 20

Classifications:



External Ids:

UMLS 70 C3165062

Summaries for May-Thurner Syndrome

MalaCards based summary : May-Thurner Syndrome, also known as iliac vein compression syndrome, is related to thrombosis and pulmonary embolism. An important gene associated with May-Thurner Syndrome is APOH (Apolipoprotein H). The drugs Hemostatics and Coagulants have been mentioned in the context of this disorder. Affiliated tissues include pancreas.

Wikipedia : 73 May-Thurner syndrome (MTS), also known as the iliac vein compression syndrome, is a condition in which... more...

Related Diseases for May-Thurner Syndrome

Diseases related to May-Thurner Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 122)
# Related Disease Score Top Affiliating Genes
1 thrombosis 31.1 F5 APOH
2 pulmonary embolism 30.6 F5 APOH
3 thrombophilia 30.5 F5 APOH
4 thrombophilia due to thrombin defect 30.5 F5 APOH
5 patent foramen ovale 30.3 F5 APOH
6 antiphospholipid syndrome 30.0 F5 APOH
7 thrombophlebitis 30.0 F5 APOH
8 protein s deficiency 29.7 F5 APOH
9 protein c deficiency 29.7 F5 APOH
10 severe pre-eclampsia 29.7 F5 APOH
11 pre-eclampsia 29.7 F5 APOH
12 vascular disease 29.6 F5 APOH
13 stroke, ischemic 29.6 F5 APOH
14 thrombocytopenia 29.4 F5 APOH
15 post-thrombotic syndrome 10.6
16 venous insufficiency 10.5
17 chronic venous insufficiency 10.4
18 limb ischemia 10.2
19 varicocele 10.2
20 myoma 10.2
21 aortic aneurysm 10.2
22 taylor's syndrome 10.2
23 aneurysm 10.2
24 prostatic hypertrophy 10.2
25 aortic aneurysm, familial abdominal, 1 10.1
26 klippel-trenaunay-weber syndrome 10.1
27 transient cerebral ischemia 10.1
28 radiculopathy 10.1
29 intracranial embolism 10.1
30 situs inversus 10.1
31 heparin-induced thrombocytopenia 10.1
32 chronic pain 10.1
33 prostatic hyperplasia, benign 10.1
34 pulmonary disease, chronic obstructive 10.1
35 pulmonary hypertension, chronic thromboembolic, without deep vein thrombosis 10.1
36 pulmonary hypertension 10.1
37 neurogenic bladder 10.1
38 prostatic adenoma 10.1
39 pyoderma 10.1
40 pyoderma gangrenosum 10.1
41 urethral calculus 10.1
42 48,xyyy 10.1
43 chronic thromboembolic pulmonary hypertension 10.1
44 cardiogenic shock 10.1
45 amyotrophic lateral sclerosis 1 10.0
46 leiomyoma, uterine 10.0
47 ovarian cancer 10.0
48 dowling-degos disease 1 10.0
49 spondylolisthesis 10.0
50 sturge-weber syndrome 10.0

Graphical network of the top 20 diseases related to May-Thurner Syndrome:



Diseases related to May-Thurner Syndrome

Symptoms & Phenotypes for May-Thurner Syndrome

Drugs & Therapeutics for May-Thurner Syndrome

Drugs for May-Thurner Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Hemostatics Phase 4
2 Coagulants Phase 4
3 Aminaftone Phase 4
4
Warfarin Approved Phase 3 81-81-2 54678486 6691
5
Nadroparin Approved, Investigational Phase 3
6
Rivaroxaban Approved 366789-02-8
7
Aspirin Approved, Vet_approved 50-78-2 2244
8 Fibrinolytic Agents
9 Anticoagulants
10 Serine Proteinase Inhibitors
11 Antithrombin III
12
protease inhibitors
13 Factor Xa Inhibitors
14 HIV Protease Inhibitors
15 Antithrombins
16 Analgesics, Non-Narcotic
17 Analgesics
18 Cyclooxygenase Inhibitors
19 Antirheumatic Agents
20 Antipyretics
21 Anti-Inflammatory Agents, Non-Steroidal
22 Anti-Inflammatory Agents
23 Platelet Aggregation Inhibitors
24
Serine Investigational, Nutraceutical 56-45-1 5951

Interventional clinical trials:

(show all 13)
# Name Status NCT ID Phase Drugs
1 Randomized Double-blind Trial Between Clinical and Endovascular Treatment in Patients With Advanced Chronic Venous Insufficiency and Iliac Venous Obstruction Completed NCT02149212 Phase 4 Phlebotonic
2 An Efficacy and Safety Study of Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression Treated With Stent Implantation (PLICTS):A Prospective Randomized Controlled Trial Recruiting NCT04067505 Phase 3 Rivaroxaban;Warfarin;Nadroparin
3 Comparison of Intravascular Ultrasound With Venography in the Diagnosis and Treatment of Iliac Vein Compression Syndrome Unknown status NCT03309969
4 Balloon Test for Iliac Vein Compression Unknown status NCT02584374
5 Color Doppler U/S vs MSCT Venography in the Diagnosis of May-Thurner Syndrome Unknown status NCT03262987
6 Prospective, Single-arm, Single Center, Pilot Study of Vascular Ultrasound Imaging Used as an Adjunct to Intravascular Ultrasound for Diagnosing Iliac Vein Obstruction Unknown status NCT02240914
7 The BARD® VENOVO™ Venous Stent Study - A Prospective, Non-Randomized, Multi-Center, Single-Arm Study of the Treatment of Iliofemoral Occlusive Disease - an Assessment for Effectiveness and Safety (VERNACULAR) Completed NCT02655887
8 Multi-detector Computer Tomography Protocol Project: Chest Imaging Technique and Case Presentation Completed NCT01206751
9 The Effect of PTA & Stenting on Intravenous Pressure in Deep Venous Obstructive Disease Before, After and During Ambulation on a Treadmill - Pilot Study. Completed NCT01846780
10 Non-interventional, Multicenter, Multinational Venous Stent Study for the Treatment of the Post-thrombotic Syndrome With Common Iliac Vein Compression Completed NCT02942394
11 Role of Intravascular Ultrasound(IVUS) in Management of Acute and Chronic Iliocaval Obstruction Recruiting NCT04024215
12 Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System Recruiting NCT04580160
13 Anticoagulant Plus Antiplatelet Therapy Following Iliac Vein Stenting Not yet recruiting NCT04694248 Rivaroxaban;Aspirin

Search NIH Clinical Center for May-Thurner Syndrome

Genetic Tests for May-Thurner Syndrome

Anatomical Context for May-Thurner Syndrome

MalaCards organs/tissues related to May-Thurner Syndrome:

40
Pancreas

Publications for May-Thurner Syndrome

Articles related to May-Thurner Syndrome:

(show top 50) (show all 363)
# Title Authors PMID Year
1
Endovascular and medical therapy of May-Thurner syndrome: Case series and scoping literature review. 61
33752850 2021
2
Diagnosis, Clinical Characteristics, and Treatment Modalities of Adolescent May-Thurner Syndrome-associated Deep Venous Thrombosis. 61
33093351 2021
3
May-Thurner syndrome and deep vein thrombosis: A series of 8 patients. 61
33810871 2021
4
May-Thurner Syndrome Is Aggravated by Pregnancy. 61
33804526 2021
5
Pediatric May-Thurner Syndrome-Systematic review and individual patient data meta-analysis. 61
33651481 2021
6
Long-term outcomes following use of a composite Wallstent-Z stent approach to iliofemoral venous stenting. 61
32827734 2021
7
May-Thurner syndrome, a diagnosis to consider in young males with no risk factors: a case report and review of the literature. 61
33736685 2021
8
Deformation mechanics of self-expanding venous stents: Modelling and experiments. 61
33730560 2021
9
May-Thurner Syndrome: An Underdiagnosed Entity. 61
33661173 2021
10
May-Thurner Syndrome from Spinal Anterolisthesis. 61
32450224 2021
11
The role of ultrasound imaging in vascular compression syndromes. 61
33555480 2021
12
Case Series of Concomitant Klippel-Trenaunay Syndrome and May-Thurner Syndrome. 61
33596770 2021
13
May-Thurner Syndrome with Calcified Uterine Leiomyoma. 61
33583897 2021
14
Ilio-Femoral Deep Vein Thrombosis Secondary to May-Thurner Syndrome With Ipsilateral Lower Limb Arterio-Venous Graft In-Situ. 61
33596777 2021
15
May-Thurner syndrome with left iliofemoral deep venous thrombosis. 61
33694348 2021
16
Incidence and severity of postthrombotic syndrome after iliofemoral thrombosis - results of the Iliaca-PTS - Registry. 61
33393383 2021
17
Iliac vein stenting guided by intravascular ultrasound without iodinated contrast medium. 61
32552609 2021
18
Finite Element Simulations of the ID Venous System to Treat Venous Compression Disorders: From Model Validation to Realistic Implant Prediction. 61
33398616 2021
19
Iliocaval Skip Stent Reconstruction Technique for Chronic Bilateral Iliocaval Venous Occlusion. 61
33153863 2020
20
Three-dimensional computed tomography venography reconstruction facilitates identification of atypical radiologic features of May-Thurner syndrome. 61
33248296 2020
21
May-Thurner syndrome in a case of severe lipodermatosclerosis. 61
33134455 2020
22
May-Thurner syndrome in pregnancy: a multi-institutional case series and review of the literature. 61
33345939 2020
23
A review into the management of May-Thurner syndrome in adolescents. 61
32474151 2020
24
Endovascular interventions in the treatment of pelvic congestion syndrome caused by May-Thurner syndrome. 61
32241734 2020
25
Co-occurrence of compression syndromes: celiac axis stenosis, superior mesenteric artery and nutcracker syndrome. 61
32755144 2020
26
Deep Vein Thrombosis Due to Fecal Impaction. 61
31764518 2020
27
A retrospective comparison of thrombectomy followed by stenting and thrombectomy alone for the management of deep vein thrombosis with May-Thurner syndrome. 61
33045391 2020
28
Deep Vein Thrombosis Secondary to Extrinsic Compression: A Case Report. 61
33133798 2020
29
Endovascular strategy for deep vein thrombosis caused by a huge uterine myoma accompanied by May-Thurner syndrome: A case report. 61
32874385 2020
30
Pressed for time: Implications of a delayed presentation of venous thromboembolism precipitated by COVID-19 and May-Thurner Syndrome. 61
32845512 2020
31
May-Thurner syndrome: an overlooked cause of venous thromboembolism. 61
32789865 2020
32
A Case of May-Thurner Syndrome. 61
33083189 2020
33
Stasis Leg Ulcers: Venous System Revises by Triggered Angiography Non-Contrast-Enhanced Sequence Magnetic Resonance Imaging. 61
32957628 2020
34
Atypical May-Thurner syndrome caused by endovascular aortic aneurysm repair. 61
32715178 2020
35
Evaluating a Novel Telescoping Catheter Set for Treatment of Central Venous Occlusions. 61
32890642 2020
36
Iliac vein stent migration with extensive cardiac damage in a patient with May-Thurner syndrome. 61
32841975 2020
37
Pelvic kidney as a cause of May-Thurner syndrome. 61
32981474 2020
38
Successful Fogarty venous thrombectomy without a skin incision for organized thrombi caused by May-Thurner syndrome. 61
32870461 2020
39
Endovascular Deep Vein Stenting of Symptomatic Post-Thrombotic and Non-Thrombotic Iliac Vein Stenotic Lesions: A Multicentre Cohort Experience from Singapore. 61
33164025 2020
40
Deep vein thrombosis of the common iliac vein caused by neurogenic heterotopic ossification in the anterior lower lumbar spine of a patient with complete paraplegia due to radiation-induced myelopathy. 61
32808906 2020
41
Contralateral limb improvement after unilateral iliac vein stenting argues against simultaneous bilateral stenting. 61
32381472 2020
42
May-Thurner Syndrome Results in Life-Threatening Condition: Phlegmasia Cerulea Dolens and Rhabdomyolysis. 61
32610273 2020
43
Clinical Outcomes of May-Thurner Syndrome in Pediatric Patients: A Single Institutional Experience. 61
32844146 2020
44
A case of phlegmasia cerulea dolens as a result of May-Thurner syndrome. 61
31926013 2020
45
May-Thurner and Paget-Schroetter Syndromes: A Review. 61
32595788 2020
46
May Thurner syndrome: description of a case with unusual clinical onset. 61
32577934 2020
47
Giant subserosal myoma causing deep venous thrombosis in a patient with pre-existing May-Thurner syndrome. 61
32280393 2020
48
Deep vein thrombosis due to May-Thurner syndrome: a case report. 61
32429980 2020
49
May-Thurner syndrome: an overlooked cause of venous thromboembolism. 61
32162703 2020
50
Vulvar Varicosities from May-Thurner Syndrome. 61
31476482 2020

Variations for May-Thurner Syndrome

Expression for May-Thurner Syndrome

Search GEO for disease gene expression data for May-Thurner Syndrome.

Pathways for May-Thurner Syndrome

GO Terms for May-Thurner Syndrome

Biological processes related to May-Thurner Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 8.62 F5 APOH

Sources for May-Thurner Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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