MCID: MYT019
MIFTS: 27

May-Thurner Syndrome

Categories: Cardiovascular diseases, Rare diseases

Aliases & Classifications for May-Thurner Syndrome

MalaCards integrated aliases for May-Thurner Syndrome:

Name: May-Thurner Syndrome 53 73
Iliac Vein Compression Syndrome 53
Iliocaval Compression Syndrome 53
May Thurner Syndrome 53
Cockett Syndrome 53

Classifications:



External Ids:

UMLS 73 C3165062

Summaries for May-Thurner Syndrome

MalaCards based summary : May-Thurner Syndrome, also known as iliac vein compression syndrome, is related to thrombosis and thrombophilia due to thrombin defect. An important gene associated with May-Thurner Syndrome is F5 (Coagulation Factor V). The drugs Aminaftone and Coagulants have been mentioned in the context of this disorder. Affiliated tissues include kidney, prostate and heart.

Related Diseases for May-Thurner Syndrome

Diseases related to May-Thurner Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Related Disease Score Top Affiliating Genes
1 thrombosis 31.1 APOH F5
2 thrombophilia due to thrombin defect 30.6 APOH F5
3 patent foramen ovale 30.1 APOH F5
4 pulmonary embolism 30.0 APOH F5
5 antiphospholipid syndrome 29.9 APOH F5
6 stroke, ischemic 29.7 APOH F5
7 thrombocytopenia 10.2
8 heparin-induced thrombocytopenia 10.2
9 amyotrophic lateral sclerosis 1 10.0
10 klippel-trenaunay-weber syndrome 10.0
11 ovarian cancer 10.0
12 sturge-weber syndrome 10.0
13 varicocele 10.0
14 atrial heart septal defect 10.0
15 lateral sclerosis 10.0
16 myoma 10.0
17 ischemia 10.0
18 radiculopathy 10.0
19 priapism 10.0
20 taylor's syndrome 10.0
21 horseshoe kidney 10.0
22 weber syndrome 10.0
23 aortic aneurysm, familial abdominal, 1 10.0
24 aortic aneurysm 10.0
25 pyoderma 10.0
26 pyoderma gangrenosum 10.0
27 acanthamoeba keratitis 9.9 APOH F5
28 spinal cord infarction 9.9 APOH F5
29 sudden sensorineural hearing loss 9.9 APOH F5
30 cerebral sinovenous thrombosis 9.9 APOH F5
31 pregnancy loss, recurrent 1 9.9 APOH F5
32 prothrombin deficiency, congenital 9.9 APOH F5
33 ischemic colitis 9.9 APOH F5
34 catastrophic antiphospholipid syndrome 9.9 APOH F5
35 retinal vascular occlusion 9.9 APOH F5
36 thrombophlebitis 9.9 APOH F5
37 carotid artery occlusion 9.9 APOH F5
38 antithrombin iii deficiency 9.9 APOH F5
39 peripheral vertigo 9.9 APOH F5
40 central retinal vein occlusion 9.9 APOH F5
41 retinal vein occlusion 9.9 APOH F5
42 intracranial thrombosis 9.9 APOH F5
43 factor xii deficiency 9.9 APOH F5
44 legg-calve-perthes disease 9.9 APOH F5
45 retinal artery occlusion 9.9 APOH F5
46 portal vein thrombosis 9.9 APOH F5
47 protein s deficiency 9.9 APOH F5
48 placental abruption 9.9 APOH F5
49 ischemic optic neuropathy 9.9 APOH F5
50 intracranial hypertension 9.9 APOH F5

Graphical network of the top 20 diseases related to May-Thurner Syndrome:



Diseases related to May-Thurner Syndrome

Symptoms & Phenotypes for May-Thurner Syndrome

Drugs & Therapeutics for May-Thurner Syndrome

Drugs for May-Thurner Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Aminaftone Phase 4
2 Coagulants Phase 4
3 Hemostatics Phase 4
4 Kava Approved, Investigational, Nutraceutical 9000-38-8

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Iliac Vein Stenting in Advanced Chronic Venous Insufficiency Completed NCT02149212 Phase 4 Phlebotonic
2 Balloon Test for Iliac Vein Compression Unknown status NCT02584374
3 Vascular Ultrasound Versus Intravascular Ultrasound for Diagnosing Iliac Vein Obstruction Unknown status NCT02240914
4 Treadmill Pilot Study (Invasive Pressure Measurements in PTS) Completed NCT01846780
5 Multi-detector Computer Tomography Protocol Project: Chest Imaging Technique and Case Presentation Completed NCT01206751
6 Comparison of Intravascular Ultrasound With Venography in the Diagnosis and Treatment of Iliac Vein Compression Syndrome Recruiting NCT03309969
7 Bern Venous Stent Registry Recruiting NCT02433054
8 Treatment of the Postthrombotic Syndrome With the Oblique Stent - TOPOS Study Active, not recruiting NCT02942394
9 Color Doppler U/S vs MSCT Venography in May-Thurner Syndrome Not yet recruiting NCT03262987

Search NIH Clinical Center for May-Thurner Syndrome

Genetic Tests for May-Thurner Syndrome

Anatomical Context for May-Thurner Syndrome

MalaCards organs/tissues related to May-Thurner Syndrome:

41
Kidney, Prostate, Heart, Spinal Cord, Placenta

Publications for May-Thurner Syndrome

Articles related to May-Thurner Syndrome:

(show top 50) (show all 208)
# Title Authors Year
1
May-Thurner Syndrome. ( 29753382 )
2018
2
Sciatic Neuralgia Caused by May-Thurner Syndrome: Case Report. ( 29772369 )
2018
3
May-Thurner Syndrome Presenting as Acute Unexplained Deep Venous Thrombosis. ( 29793013 )
2018
4
Bilateral May-Thurner syndrome refractory to iliac aneurysm repair. ( 29945821 )
2018
5
May-Thurner Syndrome Variant Identified in a Cadaver: First Reported Case. ( 29854571 )
2018
6
May-Thurner Syndrome in Operative Ankle Fracture Dislocations: A Case Report. ( 29779990 )
2018
7
Recurrent Iliofemoral Venous Thrombosis in the Setting of May-Thurner Syndrome as the Presenting Symptom of Behcet's Disease. ( 29481922 )
2018
8
Acute Iliac Vein Thrombosis SecondaryA toA Exacerbation of May-Thurner Syndrome by OverridingA Arterial Crossover Sheath. ( 29730371 )
2018
9
Stent implantation for May-Thurner syndrome with acute deep venous thrombosis: acute and long-term results from the ATOMIC (AcTive stenting for May-Thurner Iliac Compression syndrome) registry. ( 29948590 )
2018
10
May-Thurner syndrome and the risk of pulmonary embolism in patients with acute deep venous thrombosis. ( 29909851 )
2018
11
May Thurner syndrome revealed by left calf venous claudication during running, a case report. ( 29435334 )
2018
12
Contralateral Deep Vein Thrombosis after Iliac Vein Stent Placement in Patients with May-Thurner Syndrome. ( 29705226 )
2018
13
Variant May-Thurner syndrome: Compression of the left common iliac vein by the ipsilateral internal iliac artery. ( 29904487 )
2018
14
Endovascular Repair of an Abdominal Aortic Aneurysm with Iliac Vein Compression Syndrome. ( 29459568 )
2018
15
Systematic review of May-Thurner syndrome with emphasis on gender differences. ( 29290600 )
2018
16
Is May-Thurner Syndrome Combined with Left Iliac Arteriovenous Fistularare or Neglected?: Cases Report and Literature Review. ( 29777852 )
2018
17
Penile Mondor's Disease Triggered by May-Thurner Syndrome. ( 30017028 )
2018
18
Hip Arthroscopy Complicated by a Deep Vein Thrombosis in a Patient with May-Thurner Syndrome: A Case Report. ( 30045080 )
2018
19
May-Thurner Syndrome as a Rare Cause of Paradoxical Embolism in a Patient with Patent Foramen Ovale. ( 30057826 )
2018
20
May-Thurner Syndrome: A Rare Cause of Deep Venous Thrombosis. ( 30062074 )
2018
21
The Role of May-Thurner Syndrome in Recurrent Thrombosis after Catheter-Directed Thrombolysis of Deep Vein Thrombosis. ( 30092421 )
2018
22
Curious Case of Acute Unilateral Deep Vein Thrombosis: May-Thurner Syndrome. ( 30111937 )
2018
23
May-Thurner syndrome. ( 30187833 )
2018
24
Successful recanalization of the occluded vessel with the assistance of Targeted Adjustable Pharmaceutical Application System (TAPAS) in a patient with an acute deep vein thrombosis and May-Thurner syndrome. ( 30258518 )
2018
25
Impact of degree of stenosis in May-Thurner syndrome on iliac vein stenting. ( 30553783 )
2018
26
Midterm Results of Endovascular Treatment for Iliac Vein Compression Syndrome from a Single Center. ( 29428534 )
2018
27
Correlation between venous pressure gradients and intravascular ultrasound in the diagnosis of iliac vein compression syndrome. ( 29526687 )
2018
28
Application of computed tomography venography in the diagnosis and severity assessment of iliac vein compression syndrome: A retrospective study. ( 30142841 )
2018
29
An Extensive Unprovoked Left Lower Extremity Deep Vein Thrombosis Secondary to an Anatomical Anomaly: A Case of May-Thurner Syndrome. ( 28458813 )
2017
30
Long-term results of endovascular treatment for May-Thurner syndrome. ( 28819959 )
2017
31
Contemporary outcomes after venography-guided treatment of patients with May-Thurner syndrome. ( 28818219 )
2017
32
May-Thurner syndrome: old acquaintance, new perspective : Case report. ( 28321560 )
2017
33
Epidural Injections Contraindicated for Lumbar Radiculopathy in May-Thurner Syndrome: A Case Report. ( 28697031 )
2017
34
Acute iliofemoral DVT in the presence of May-Thurner syndrome. ( 28181918 )
2017
35
An Unusual Endovascular Therapeutic Approach for a Rare Case of May-Thurner Syndrome. ( 28260745 )
2017
36
Comparison of clinical outcomes of pharmacomechanical thrombectomy in iliac vein thrombosis with and without may-thurner syndrome. ( 28291305 )
2017
37
Surgical Thrombectomy, Fibrinolysis, Angioplasty and Stenting: A Combined Approach for Treatment of a May-Thurner Syndrome Presenting as Phlegmasia Cerulea Dolens. ( 29701417 )
2017
38
Female Runner With Painful Left Thigh Swelling: A Case of May-Thurner Syndrome. ( 28662854 )
2017
39
Left-Sided Varicocele as a Rare Presentation of May-Thurner Syndrome. ( 28258018 )
2017
40
Endovascular Management of May-Thurner Syndrome in Adolescents: A Single-Center Experience. ( 27818112 )
2017
41
May-Thurner syndrome caused by a huge uterine myoma. ( 29296055 )
2017
42
May-Thurner syndrome: missed diagnosis and missed early treatment? ( 28895971 )
2017
43
Hemodialysis catheter dysfunction caused by May-Thurner syndrome. ( 28777404 )
2017
44
May-Thurner syndrome: an often overlooked cause for refractory venous leg ulcers. ( 28251803 )
2017
45
Acute iliofemoral DVT in the presence of May-Thurner syndrome. ( 28225397 )
2017
46
Endovascular Treatment of May-Thurner Syndrome-Related Symptomatic Venous Aneurysm. ( 28841957 )
2017
47
Pharmacomechanical Thrombolysis for Deep Vein Thrombosis in May-Thurner Syndrome. ( 29049090 )
2017
48
Intravascular Ultrasound-Guided Intervention for May-Thurner Syndrome. ( 28579688 )
2017
49
Thrombosis of the Inferior Vena Cava after Endovascular Aortic Repair in a Patient with May-Thurner Syndrome: Case Report and Literature Review. ( 28163175 )
2017
50
Extensive Intracardiac and Deep Venous Thromboses in a Young Woman with Heparin-Induced Thrombocytopenia and May-Thurner Syndrome. ( 28465848 )
2017

Variations for May-Thurner Syndrome

Expression for May-Thurner Syndrome

Search GEO for disease gene expression data for May-Thurner Syndrome.

Pathways for May-Thurner Syndrome

GO Terms for May-Thurner Syndrome

Biological processes related to May-Thurner Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 8.62 APOH F5

Sources for May-Thurner Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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