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MCID: MCH001
MIFTS: 17

Mechanical Ectropion

Categories: Skin diseases
Genes Related diseases Publications Pathways
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Aliases & Classifications for Mechanical Ectropion

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MalaCards integrated aliases for Mechanical Ectropion:

Name: Mechanical Ectropion 12 15 71

Classifications:

MalaCards categories:
Anatomical: Skin diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:1569
ICD9CM 34 374.12
SNOMED-CT 67 45020000
UMLS 71 C0155194
Sources

Summaries for Mechanical Ectropion

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MalaCards based summary : Mechanical Ectropion is related to ectropion and optic nerve neoplasm. An important gene associated with Mechanical Ectropion is NFIC (Nuclear Factor I C), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Dendritic Cells Developmental Lineage Pathway. Related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

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Related Diseases for Mechanical Ectropion

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Diseases related to Mechanical Ectropion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 54)
# Related Disease Score Top Affiliating Genes
1 ectropion 10.1
2 optic nerve neoplasm 10.0 NFIC NF1
3 childhood malignant schwannoma 10.0 NFIC NF1
4 optic nerve glioma 10.0 NFIC NF1
5 elephantiasis 10.0 NFIC NF1
6 plexiform neurofibroma 10.0 NFIC NF1
7 epithelioid neurofibroma 10.0 NF1 CD34
8 neurofibroma 10.0 NF1 CD34
9 fibroma 10.0 NF1 CD34
10 pacinian tumor 10.0 NF1 CD34
11 plexiform schwannoma 10.0 NF1 CD34
12 small intestine leiomyoma 10.0 NF1 CD34
13 subungual glomus tumor 10.0 NF1 CD34
14 glomus tumor 10.0 NF1 CD34
15 adult malignant schwannoma 10.0 NF1 CD34
16 atypical neurofibroma 10.0 NF1 CD34
17 orbital cancer 10.0 NF1 CD34
18 cellular schwannoma 10.0 NF1 CD34
19 epithelioid malignant peripheral nerve sheath tumor 10.0 NF1 CD34
20 malignant peripheral nerve sheath tumor 10.0 NF1 CD34
21 gliofibroma 10.0 NF1 CD34
22 malignant spindle cell melanoma 10.0 NF1 CD34
23 adult xanthogranuloma 10.0 NF1 CD34
24 exophthalmos 9.9 NF1 CD34
25 paraganglioma and gastric stromal sarcoma 9.9 NF1 CD34
26 central nervous system benign neoplasm 9.9 NF1 CD34
27 lipomatosis, multiple 9.9 NF1 CD34
28 skeletal muscle cancer 9.9 NF1 CD34
29 muscle cancer 9.9 NF1 CD34
30 skin benign neoplasm 9.9 NF1 CD34
31 cardiovascular organ benign neoplasm 9.9 NF1 CD34
32 rhinosporidiosis 9.9
33 neurilemmoma 9.9 NF1 CD34
34 neuroma 9.9 NF1 CD34
35 dedifferentiated liposarcoma 9.9 NF1 CD34
36 liposarcoma 9.9 NF1 CD34
37 orbit rhabdomyosarcoma 9.9 NF1 IFNA2
38 moyamoya disease 1 9.8 NF1 CD34
39 sarcoma, synovial 9.8 NF1 CD34
40 mucosal melanoma 9.8 NF1 IFNA2
41 chronic neutrophilic leukemia 9.8 IFNA2 CD34
42 peripheral nervous system neoplasm 9.8 NF1 CD34
43 vascular cancer 9.8 IFNA2 CD34
44 mastocytosis, cutaneous 9.7 IFNA2 CD34
45 lymphangioma 9.7 IFNA2 CD34
46 melanoma, cutaneous malignant 1 9.7 NF1 IFNA2
47 neurofibrosarcoma 9.7 NFIC NF1 CD34
48 neurofibromatosis, type i 9.7 NFIC NF1 CD34
49 acquired immunodeficiency syndrome 9.6 IFNA2 CD34
50 hemangioma 9.6 IFNA2 CD34

Comorbidity relations with Mechanical Ectropion via Phenotypic Disease Network (PDN):


Facial Paralysis

Graphical network of the top 20 diseases related to Mechanical Ectropion:



Diseases related to Mechanical Ectropion
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Symptoms & Phenotypes for Mechanical Ectropion

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GenomeRNAi Phenotypes related to Mechanical Ectropion according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-105 9.1 NFIC
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-115 9.1 NFIC
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 9.1 NFIC
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-127 9.1 NFIC
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-178 9.1 IFNA2
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-20 9.1 IFNA2
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Drugs & Therapeutics for Mechanical Ectropion

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Search Clinical Trials , NIH Clinical Center for Mechanical Ectropion

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Genetic Tests for Mechanical Ectropion

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Anatomical Context for Mechanical Ectropion

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Publications for Mechanical Ectropion

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Articles related to Mechanical Ectropion:

(show all 11)
# Title Authors PMID Year
1
A rare case of conjunctival malignant melanoma with orbital invasion. 61
31523071 2019
2
IgG4-Related Disease of the Punctum and Canaliculus. 61
26866331 2017
3
"Dry Lake" technique for the treatment of hypertrophic bleb following XEN(®) Gel Stent placement. 61
26008922 2015
4
Giant mass conjunctival rhinosporidiosis causing severe mechanical ectropion. 61
23360029 2012
5
Multiple apocrine hidrocystomas of the eyelids. 61
22489861 2012
6
Ectropion. 61
20590414 2010
7
Hemangiopericytoma-solitary fibrous tumor of the eyelid. 61
20090488 2010
8
Selective embolization and resection of a large noninvoluting congenital hemangioma of the lower eyelid. 61
19300152 2009
9
[Eyelid ectropion in Down's syndrome related to allergic conjunctivitis: case report]. 61
17906771 2007
10
Drug-induced ectropion: what is best practice? 61
17270684 2007
11
Mechanical ectropion repair using tarsal rotation sutures. 61
386207 1979
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Variations for Mechanical Ectropion

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Expression for Mechanical Ectropion

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Search GEO for disease gene expression data for Mechanical Ectropion.
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Pathways for Mechanical Ectropion

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Pathways related to Mechanical Ectropion according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.02 IFNA2 CD34
2
Dendritic Cells Developmental Lineage Pathway 64
10.49 IFNA2 CD34
Sources

GO Terms for Mechanical Ectropion

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Sources for Mechanical Ectropion

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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