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MCID: MCK004
MIFTS: 21

Meckel's Diverticulitis

Categories: Gastrointestinal diseases
Genes Tissues Related diseases Publications
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Aliases & Classifications for Meckel's Diverticulitis

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MalaCards integrated aliases for Meckel's Diverticulitis:

Name: Meckel's Diverticulitis 12 15 71
Meckel Diverticulitis 12

Classifications:

MalaCards categories:
Anatomical: Gastrointestinal diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:8408
NCIt 49 C27300
SNOMED-CT 67 48241004
UMLS 71 C0267497
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Summaries for Meckel's Diverticulitis

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Disease Ontology : 12 A diverticulits characterized by the inflammation of a congenital diverticulum, which is a slight bulge of the small intestine present at birth.

MalaCards based summary : Meckel's Diverticulitis, also known as meckel diverticulitis, is related to intestinal volvulus and diverticulitis. An important gene associated with Meckel's Diverticulitis is MID1 (Midline 1). Affiliated tissues include small intestine, pancreas and appendix, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

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Related Diseases for Meckel's Diverticulitis

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Diseases related to Meckel's Diverticulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
# Related Disease Score Top Affiliating Genes
1 intestinal volvulus 29.6 KCNE1 CRP
2 diverticulitis 11.0
3 meckel diverticulum 10.8
4 appendicitis 10.7
5 intestinal obstruction 10.5
6 crohn's disease 10.3
7 intussusception 10.3
8 peritonitis 10.3
9 ileus 10.3
10 schistosoma mansoni infection, susceptibility/ 10.2
11 schistosomiasis 10.2
12 crohn's colitis 10.1
13 leiomyoma 10.1
14 ileitis 10.0
15 diarrhea 10.0
16 cholecystitis 10.0
17 intestinal perforation 10.0
18 acute pancreatitis 10.0
19 pancreatitis 10.0
20 colonic disease 10.0
21 peptic ulcer disease 10.0
22 paralytic ileus 10.0
23 enterovesical fistula 10.0
24 lemierre's syndrome 9.9 NDUFA5 CRP
25 hydrops of gallbladder 9.8 NDUFA5 CRP
26 peripheral vertigo 9.7 KCNE1 CRP
27 heart conduction disease 9.6 KCNE1 CRP
28 atrial fibrillation 9.4 KCNE1 CRP

Graphical network of the top 20 diseases related to Meckel's Diverticulitis:



Diseases related to Meckel's Diverticulitis
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Symptoms & Phenotypes for Meckel's Diverticulitis

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GenomeRNAi Phenotypes related to Meckel's Diverticulitis according to GeneCards Suite gene sharing:

26 (show all 31)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 10.29 CTAGE1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-101 10.29 CTAGE1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-103 10.29 CTAGE1 MID1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-108 10.29 MID1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-12 10.29 CTAGE1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-121 10.29 NDUFA5
7 Increased shRNA abundance (Z-score > 2) GR00366-A-122 10.29 NDUFA5
8 Increased shRNA abundance (Z-score > 2) GR00366-A-126 10.29 CTAGE1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-128 10.29 MID1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-138 10.29 NDUFA5
11 Increased shRNA abundance (Z-score > 2) GR00366-A-152 10.29 CTAGE1 NDUFA5
12 Increased shRNA abundance (Z-score > 2) GR00366-A-159 10.29 CTAGE1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-162 10.29 KCNE1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-177 10.29 CTAGE1 KCNE1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-178 10.29 CTAGE1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-180 10.29 KCNE1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-214 10.29 CTAGE1 MID1 KCNE1 NDUFA5
18 Increased shRNA abundance (Z-score > 2) GR00366-A-23 10.29 CTAGE1 MID1 KCNE1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-26 10.29 CTAGE1
20 Increased shRNA abundance (Z-score > 2) GR00366-A-3 10.29 MID1
21 Increased shRNA abundance (Z-score > 2) GR00366-A-4 10.29 CTAGE1
22 Increased shRNA abundance (Z-score > 2) GR00366-A-42 10.29 KCNE1
23 Increased shRNA abundance (Z-score > 2) GR00366-A-43 10.29 CTAGE1 NDUFA5
24 Increased shRNA abundance (Z-score > 2) GR00366-A-57 10.29 KCNE1
25 Increased shRNA abundance (Z-score > 2) GR00366-A-63 10.29 NDUFA5
26 Increased shRNA abundance (Z-score > 2) GR00366-A-70 10.29 NDUFA5
27 Increased shRNA abundance (Z-score > 2) GR00366-A-73 10.29 KCNE1
28 Increased shRNA abundance (Z-score > 2) GR00366-A-76 10.29 CTAGE1
29 Increased shRNA abundance (Z-score > 2) GR00366-A-88 10.29 KCNE1
30 Increased shRNA abundance (Z-score > 2) GR00366-A-90 10.29 NDUFA5
31 Increased shRNA abundance (Z-score > 2) GR00366-A-93 10.29 KCNE1
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Drugs & Therapeutics for Meckel's Diverticulitis

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Search Clinical Trials , NIH Clinical Center for Meckel's Diverticulitis

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Genetic Tests for Meckel's Diverticulitis

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Anatomical Context for Meckel's Diverticulitis

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MalaCards organs/tissues related to Meckel's Diverticulitis:

40
Small Intestine, Pancreas, Appendix
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Publications for Meckel's Diverticulitis

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Articles related to Meckel's Diverticulitis:

(show top 50) (show all 150)
# Title Authors PMID Year
1
Intestinal perforation in unusual location. 61
31696721 2019
2
Double trouble: first report of duplicated Meckel's diverticulitis with perforation. 61
30690868 2019
3
Surprising image of an enterovesical fistula resulting from a perforated Meckel's diverticulitis. 61
30208509 2019
4
Perforated Meckel's diverticulitis in an adult as an atypical cause of abdominal pain. 61
31493947 2019
5
Intestinal knot in acute Meckel's diverticulitis. 61
31767613 2019
6
Gangrenous giant Meckel's diverticulitis masquerading acute appendicitis: a surgical conundrum. 61
29695030 2019
7
Perforated Meckel's Diverticulitis Mimicking Penetrating Crohn's Disease. 61
30031176 2019
8
[Clinical characteristics and next generation sequencing of three cases of Listeria monocytogenes meningitis with complications]. 61
31352745 2019
9
Tomographic findings in Meckel's diverticulitis. 61
31435091 2019
10
Jejunal diverticulitis. 61
30740206 2019
11
"Learning from my experience": Acute abdomen - Perforated Meckel's diverticulitis. 61
31061851 2019
12
Case report: Diverticulitis complicating a giant Meckel's divertuculum. 61
31731084 2019
13
Meckel's diverticulitis: a laparoscopic approach. 61
30238766 2018
14
A Rare Cause of Abdominal Pain in Adults: Meckel's Diverticulitis. 61
30631257 2018
15
Ulcerative colitis in an infant aged 20 months. A case report. 61
30016039 2018
16
Ascaridial Volvulus: An Uncommon Cause of Ileal Perforation. 61
30046214 2018
17
Meckel's diverticulitis: a rare cause of abdominal pain during pregnancy. 61
27061447 2018
18
Meckel's Diverticulum in Crohn's Disease Revisited: A Case of Meckel's Diverticulitis in a Patient with Stricturing Crohn's Disease. 61
30148017 2018
19
Enterobius vermicularis infestation leading to Meckel's diverticulitis in an adolescent boy: An extremely rare presentation. 61
29403216 2018
20
Perforated Giant Meckel Diverticulitis in an elderly patient: Case report and review of the literature. 61
29453164 2018
21
Perforated Meckel's Diverticulitis. 61
28744739 2017
22
Umbilicus and its extensive clinical repertoire. 61
29148196 2017
23
Meckel's Diverticulitis Masquerading as Acute Pancreatitis: A Diagnostic Dilemma. 61
29279643 2017
24
Imaging Findings of the Unusual Presentations, Associations and Clinical Mimics of Acute Appendicitis. 61
29123444 2017
25
Meckel's diverticulitis caused by an enterolith: A rare presentation of an acute abdomen in an adult. 61
27788926 2017
26
Clinical characteristics of Meckel diverticulum in children: A retrospective review of a 15-year single-center experience. 61
28796070 2017
27
Meckel's diverticulitis in adults: study of 15 patients. 61
28283269 2017
28
Non-Meckel Small Intestine Diverticulitis. 61
29033764 2017
29
Meckel's diverticulum perforated by a fishbone. An unusual presentation. 61
28240037 2017
30
Case 240: Meckel Diverticulitis. 61
28318437 2017
31
Meckel's diverticulitis: a rare entity of Meckel's diverticulum. 61
28064243 2017
32
A curious case of Meckel's diverticulum. 61
27770121 2016
33
Perforated Meckel's Diverticulum. 61
27574358 2016
34
Ileal stricture following Meckel's diverticulitis: a rare cause of intestinal obstruction. 61
27146826 2016
35
Point-of-Care Ultrasonography for Appendicitis Uncovers Two Alternate Diagnoses. 61
26785100 2016
36
Giant Meckel's diverticulum torsion that mimics adnexal pathology. 61
27261632 2016
37
Suppurative meckel diiverticulum in a 3-year-old girl presenting with periumbilical cellulitis. 61
25866736 2015
38
Meckel's diverticulum--a rare cause of intestinal obstruction in adults. 61
25970960 2015
39
Meckel's Diverticulitis as a Cause of an Acute Abdomen in the Second Trimester of Pregnancy: Laparoscopic Management. 61
25648324 2015
40
Giant Meckel's diverticulum: An exceptional cause of intestinal obstruction. 61
24672650 2014
41
Two cases of omental torsion mimicking acute appendicitis. 61
24834389 2014
42
Meckel's diverticulitis causing intestinal obstruction in a 3 month old infant. 61
24381631 2013
43
Invaginated Meckel's diverticulum: a rare cause of small intestine intussusception in adults. 61
23552542 2013
44
[Meckel's diverticulitis in the early postoperative course after appendectomy]. 61
24279258 2013
45
Simultaneous Meckel's diverticulitis and appendicitis: a rare complication in puerperium. 61
23578408 2013
46
Intussusception secondary to a meckel diverticulum in an adolescent. 61
23547727 2013
47
Complicated Meckel's diverticulum and therapeutic management. 61
25931848 2013
48
Dual pathology in a patient with right lower quadrant pain. 61
23997560 2012
49
Perforated midgut diverticulitis: revisited. 61
23002340 2012
50
Meckel's diverticulitis in Amyand's hernia. 61
22527816 2012
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Variations for Meckel's Diverticulitis

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Expression for Meckel's Diverticulitis

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Search GEO for disease gene expression data for Meckel's Diverticulitis.
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Pathways for Meckel's Diverticulitis

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GO Terms for Meckel's Diverticulitis

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Sources for Meckel's Diverticulitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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