MCID: MCN007
MIFTS: 54

Meconium Aspiration Syndrome

Categories: Rare diseases, Fetal diseases, Respiratory diseases

Aliases & Classifications for Meconium Aspiration Syndrome

MalaCards integrated aliases for Meconium Aspiration Syndrome:

Name: Meconium Aspiration Syndrome 12 53 59 55 44 15 73
Neonatal Aspiration of Meconium 12
Meconium Aspiration 12
Mas 53

Characteristics:

Orphanet epidemiological data:

59
meconium aspiration syndrome
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: Infancy,Neonatal;

Classifications:

Orphanet: 59  
Rare respiratory diseases


External Ids:

Disease Ontology 12 DOID:11049
MeSH 44 D008471
NCIt 50 C87093
Orphanet 59 ORPHA70588
MESH via Orphanet 45 D008471
UMLS via Orphanet 74 C0025048
ICD10 via Orphanet 34 P24.0
UMLS 73 C0025048

Summaries for Meconium Aspiration Syndrome

NIH Rare Diseases : 53 Meconium aspiration syndrome is a serious condition in which a newborn breathes a mixture of meconium and amniotic fluid into the lungs around the time of delivery. This can cause breathing difficulties due to swelling (inflammation) in the baby's lungs after birth. Treatment may include suctioning the newborn's mouth as soon as the head emerges during delivery, deep suctioning of the windpipe, antibiotics to treat infection, oxygen to keep blood levels normal, and radiant heat to maintain body temperature. In severe cases, the baby may need assistance breathing (ventilator).

MalaCards based summary : Meconium Aspiration Syndrome, also known as neonatal aspiration of meconium, is related to endocarditis and respiratory failure, and has symptoms including apnea, cheyne-stokes respiration and coughing. An important gene associated with Meconium Aspiration Syndrome is EDN1 (Endothelin 1), and among its related pathways/superpathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. The drugs Poractant alfa and Misoprostol have been mentioned in the context of this disorder. Affiliated tissues include lung, and related phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and homeostasis/metabolism

Wikipedia : 76 Meconium aspiration syndrome (MAS) also known as neonatal aspiration of meconium is a medical condition... more...

Related Diseases for Meconium Aspiration Syndrome

Diseases related to Meconium Aspiration Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 246)
# Related Disease Score Top Affiliating Genes
1 endocarditis 30.0 CXCL8 IL6 TNF
2 respiratory failure 29.0 CXCL8 SCGB1A1 SFTPB TNF
3 asthma 25.8 CSF2 CXCL8 EDN1 IFNG IL6 SCGB1A1
4 pulmonary hypertension, neonatal 11.1
5 recurrent corneal erosion 10.7 CXCL8 IL6
6 bagassosis 10.7 CXCL8 IL6
7 acute transverse myelitis 10.7 CXCL8 IL6
8 denture stomatitis 10.7 CXCL8 IL6
9 papillary conjunctivitis 10.7 CXCL8 IL6
10 funisitis 10.7 CXCL8 IL6
11 vaginal disease 10.6 CXCL8 IL6
12 preterm premature rupture of the membranes 10.6 CXCL8 IL6
13 endometrial disease 10.6 CXCL8 IL6
14 vaginitis 10.6 CXCL8 IL6
15 necrotizing fasciitis 10.6 CXCL8 IL6
16 tungiasis 10.6 CXCL8 TNF
17 scorpion envenomation 10.6 IL6 TNF
18 trichuriasis 10.6 CXCL8 TNF
19 haemophilus influenzae 10.6 CXCL8 TNF
20 bacteriuria 10.6 CXCL8 IL6
21 leukomalacia 10.6 IL6 TNF
22 angioimmunoblastic lymphadenopathy with dysproteinemia 10.6 IL6 TNF
23 radiculopathy 10.6 CXCL8 IL6
24 critical limb ischemia 10.6 IL6 TNF
25 cowpox 10.6 CXCL8 IL6
26 null-cell leukemia 10.6 IL6 TNF
27 retinitis pigmentosa 55 10.6 IL6 TNF
28 mycobacterium abscessus 10.6 CXCL8 TNF
29 anca-associated vasculitis 10.6 IL6 TNF
30 laryngitis 10.5 IL6 TNF
31 acute vascular insufficiency of intestine 10.5 IL6 TNF
32 posterior urethral valves 10.5 IL6 TNF
33 poems syndrome 10.5 IL6 TNF
34 dental pulp disease 10.5 CXCL8 TNF
35 burning mouth syndrome 10.5 IL6 TNF
36 central nervous system vasculitis 10.5 IL6 TNF
37 engraftment syndrome 10.5 CSF2 CXCL8
38 osteosclerotic myeloma 10.5 IL6 TNF
39 stachybotrys chartarum 10.5 IL6 TNF
40 acute cystitis 10.5 CXCL8 IL6
41 felty syndrome 10.5 CSF2 CXCL8
42 listeriosis 10.5 IL6 TNF
43 paraquat lung 10.5 SCGB1A1 SFTPB
44 neutrophilia, hereditary 10.5 CSF2 IL6
45 ischemic heart disease 10.5 IL6 TNF
46 crimean-congo hemorrhagic fever 10.5 IL6 TNF
47 toxic pneumonitis 10.5 SCGB1A1 SFTPB
48 monoclonal gammopathy of uncertain significance 10.5 IL6 TNF
49 post-transplant lymphoproliferative disease 10.5 IL6 TNF
50 tuberculous meningitis 10.4 CXCL8 TNF

Graphical network of the top 20 diseases related to Meconium Aspiration Syndrome:



Diseases related to Meconium Aspiration Syndrome

Symptoms & Phenotypes for Meconium Aspiration Syndrome

UMLS symptoms related to Meconium Aspiration Syndrome:


apnea, cheyne-stokes respiration, coughing, dyspnea, hoarseness

GenomeRNAi Phenotypes related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 8.8 CSF2 CXCL8 TNF

MGI Mouse Phenotypes related to Meconium Aspiration Syndrome:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.92 IFNG IL6 SCGB1A1 CPS1 SFTPB CSF2
2 mortality/aging MP:0010768 9.86 IFNG IL6 SCGB1A1 CPS1 SFTPB CSF2
3 endocrine/exocrine gland MP:0005379 9.85 EDN1 IFNG IL6 SCGB1A1 CSF2 TNF
4 neoplasm MP:0002006 9.55 IFNG IL6 SCGB1A1 CSF2 TNF
5 renal/urinary system MP:0005367 9.35 EDN1 IFNG IL6 SCGB1A1 CSF2
6 respiratory system MP:0005388 9.1 IFNG IL6 SCGB1A1 SFTPB CSF2 TNF

Drugs & Therapeutics for Meconium Aspiration Syndrome

Drugs for Meconium Aspiration Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 32)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Poractant alfa Approved Phase 4 129069-19-8
2
Misoprostol Approved Phase 4,Not Applicable 59122-46-2 5282381
3
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
4 Vasodilator Agents Phase 4,Phase 2,Phase 3
5 Pulmonary Surfactants Phase 4,Phase 3,Not Applicable
6 Respiratory System Agents Phase 4,Phase 3,Not Applicable
7 Pharmaceutical Solutions Phase 4
8 Phosphodiesterase 5 Inhibitors Phase 4
9 Phosphodiesterase Inhibitors Phase 4
10 Sildenafil Citrate Phase 4 171599-83-0
11 Antacids Phase 4
12 Anti-Ulcer Agents Phase 4
13 Gastrointestinal Agents Phase 4
14 Oxytocics Phase 4
15 Citrate Nutraceutical Phase 4
16
Alprostadil Approved, Investigational Phase 2, Phase 3 745-65-3 149351 5280723
17
Nitric Oxide Approved Phase 3 10102-43-9 145068 160954
18 Platelet Aggregation Inhibitors Phase 2, Phase 3
19 Vasoconstrictor Agents Phase 3
20 Anti-Asthmatic Agents Phase 3
21 Antioxidants Phase 3
22 Autonomic Agents Phase 3
23 Bronchodilator Agents Phase 3
24 Endothelium-Dependent Relaxing Factors Phase 3
25 Neurotransmitter Agents Phase 3
26 Peripheral Nervous System Agents Phase 3
27 Protective Agents Phase 3
28
Dinoprostone Approved Not Applicable 363-24-6 5280360
29
Oxytocin Approved, Vet_approved Not Applicable 50-56-6 439302 53477758
30 Antibodies
31 Immunoglobulins
32 Pomegranate Nutraceutical Not Applicable

Interventional clinical trials:

(show all 31)
# Name Status NCT ID Phase Drugs
1 Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns Completed NCT01757782 Phase 4 Oral Sildenafil;Placebo (distilled water)
2 Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome Completed NCT02041546 Phase 4 Lung lavage with surfactant;Bolus surfactant
3 Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial Recruiting NCT02639429 Phase 4 Vaginal Misoprostol
4 Intravenous Iron for Iron-deficiency Anemia in Pregnancy: a Randomized Controlled Trial Recruiting NCT03438227 Phase 4 Iron dextran;Ferrous sulfate 325mg
5 Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium Aspiration Unknown status NCT00312507 Phase 3 Bovine Lipid Extract Surfactant (administered by lavage);Bovine Lipid Extract Surfactant (administered by bolus)
6 Labor Induction and Maternal BMI, Comparison of Different Pre-induction Cervical Ripening Methods Unknown status NCT02223949 Phase 2, Phase 3 PGE1 tablet
7 Late Hypothermia for Hypoxic-Ischemic Encephalopathy Completed NCT00614744 Phase 2, Phase 3
8 Phase III Randomized Study of Lucinactant in Full Term Newborn Infants With Meconium Aspiration Syndrome Terminated NCT00004500 Phase 3 Lucinactant
9 Inhaled Nitric Oxide Study for Respiratory Failure in Newborns Terminated NCT00005776 Phase 3 Inhaled nitric oxide;Placebo
10 Early Inhaled Nitric Oxide for Respiratory Failure in Newborns Terminated NCT00005773 Phase 3 Inhaled Nitric Oxide;Standard iNO therapy
11 Helium Oxygen Mixture in the Treatment of Meconium Aspiration Syndrome Unknown status NCT02620891 Not Applicable
12 High Flow Ventilation With Volume Guarantee Unknown status NCT02571231 Not Applicable
13 Role and Molecular Mechanism of Farnesoid X Receptor(FXR) and RIPK3 in the Formation of Acute Respiratory Distress Syndrome in Neonates Unknown status NCT02598648 Not Applicable
14 Pomegranate to Reduce Maternal and Fetal Oxidative Stress and to Improve Outcome in Pregnancies Complicated With Preterm Premature Rupture of Membranes Unknown status NCT02069587 Not Applicable
15 Effect Of Intrapartum Oropharyngeal (IP-OP) Suction on Meconium Aspiration Syndrome Completed NCT01328483 Not Applicable
16 Comparison Of Surfactant Lung Lavage With Standard Care In The Treatment Of Meconium Aspiration Syndrome Completed NCT01310621 Not Applicable Bovine surfactant
17 Use of Heliox in the Management of Neonates With Meconium Aspiration Syndrome Completed NCT01274845 Not Applicable
18 Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained Babies Completed NCT01758822 Not Applicable
19 Effect of Gastric Lavage in Preventing Feeding Problems in Babies Born With Meconium Stained Amniotic Fluid Completed NCT01306500 Not Applicable
20 Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO Completed NCT00371241
21 Post Term Pregnancy - Induction of Labor or Monitoring of Pregnancy Completed NCT00385229 Not Applicable induction of labor
22 Improving Teamwork for Neonatal Resuscitation Completed NCT00651794 Not Applicable
23 Pulmonary Function Using Non-invasive Forced Oscillometry Recruiting NCT03346343 Not Applicable
24 Prediction of Fetal Macrosomia by US Recruiting NCT03451838
25 PREdelivery Placental Biomarkers- Pregnancy and Delivery Outcome Recruiting NCT03100084
26 A Randomized Trial of Induction Versus Expectant Management Active, not recruiting NCT01990612 Not Applicable
27 Meconium Aspiration and Tracheal Suctioning—Feasibility Study Not yet recruiting NCT02708563 Not Applicable
28 Induction of Labor Versus Expectant Management of Large for Gestational Age/Macrosomic Babies at Term. A Multi-center Trial Not yet recruiting NCT02315820 Not Applicable
29 Detection of Epileptiform Activity in Severe Preeclampsia Not yet recruiting NCT03494517 Magnesium Sulfate
30 Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation Terminated NCT00729989 Not Applicable
31 Optimizing Management of the 2nd Stage of Labor: Multicenter Randomized Trial Terminated NCT02137200 Not Applicable

Search NIH Clinical Center for Meconium Aspiration Syndrome

Cochrane evidence based reviews: meconium aspiration syndrome

Genetic Tests for Meconium Aspiration Syndrome

Anatomical Context for Meconium Aspiration Syndrome

MalaCards organs/tissues related to Meconium Aspiration Syndrome:

41
Lung

Publications for Meconium Aspiration Syndrome

Articles related to Meconium Aspiration Syndrome:

(show top 50) (show all 300)
# Title Authors Year
1
Surfactant Lung Lavage vs. Standard Care in the Treatment of Meconium Aspiration Syndrome-A Randomized Trial. ( 29878264 )
2018
2
Controlled hypothermia may improve surfactant function in asphyxiated neonates with or without meconium aspiration syndrome. ( 29420583 )
2018
3
The Impact of Therapeutic Hypothermia on Pulmonary Hemodynamics of Meconium Aspiration Syndrome. ( 29590531 )
2018
4
Modified porcine surfactant enriched by recombinant human superoxide dismutase for experimental meconium aspiration syndrome. ( 29684443 )
2018
5
Effect of Nasal Continuous Positive Airway Pressure on Infants With Meconium Aspiration Syndrome: A Randomized Clinical Trial. ( 29204652 )
2018
6
Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome. ( 29486477 )
2018
7
Activation of Toll-like receptors in meconium aspiration syndrome. ( 29095429 )
2018
8
Reply to: The Impact of Therapeutic Hypothermia on Pulmonary Hemodynamics of Meconium Aspiration Syndrome. ( 29590532 )
2018
9
Outcome of Neonates with Meconium Aspiration Syndrome at the University Hospital of the West Indies, Jamaica: A Resource-Limited Setting. ( 28499308 )
2017
10
Meconium aspiration syndrome: risk factors and predictors of severity. ( 29219011 )
2017
11
Placental Lesions in Meconium Aspiration Syndrome. ( 28793392 )
2017
12
Procalcitonin as Predictor of Bacterial Infection in Meconium Aspiration Syndrome. ( 29287292 )
2017
13
Erythropoietin may attenuate lung inflammation in a rat model of meconium aspiration syndrome. ( 27266360 )
2016
14
Lung inflammatory and oxidative alterations after exogenous surfactant therapy fortified with budesonide in rabbit model of meconium aspiration syndrome. ( 28006947 )
2016
15
Current Concepts in the Management of Meconium Aspiration Syndrome. ( 27206687 )
2016
16
Detrimental Complications Of Meconium Aspiration Syndrome And Their Impact On Outcome. ( 28712223 )
2016
17
Surfactant therapy and antibiotics in neonates with meconium aspiration syndrome: a systematic review and meta-analysis. ( 27109092 )
2016
18
Inflammation in meconium aspiration syndrome-One of many heads of the hydra. ( 26773259 )
2016
19
Lung ultrasonography to diagnose meconium aspiration syndrome of the newborn. ( 27807253 )
2016
20
Inflammatory indices in meconium aspiration syndrome. ( 26663621 )
2016
21
Hypothermia and Meconium Aspiration Syndrome: International Multicenter Retrospective Cohort Study. ( 27479063 )
2016
22
Tidal Volume Requirement in Mechanically Ventilated Infants with Meconium Aspiration Syndrome. ( 25738789 )
2015
23
Efficiency of high-frequency oscillatory ventilation combined with pulmonary surfactant in the treatment of neonatal meconium aspiration syndrome. ( 26550439 )
2015
24
Risk factors differentiating mild/moderate from severe meconium aspiration syndrome in meconium-stained neonates. ( 25629015 )
2015
25
Meconium Aspiration Syndrome: A Role for Fetal Systemic Inflammation. ( 26484777 )
2015
26
To study prevalence of persistent pulmonary hypertension in newborn with meconium aspiration syndrome in western Rajasthan, India: a prospective observational study. ( 25586320 )
2015
27
Meconium aspiration syndrome in infants of HIV-positive women: a case-control study. ( 25999326 )
2015
28
Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies. ( 25721501 )
2015
29
Treatment of neonates with meconium aspiration syndrome by proportional assist ventilation and synchronized intermittent mandatory ventilation: a comparison study. ( 26633188 )
2015
30
Effects on Lung Function of Small-Volume Conventional Ventilation and High-Frequency Oscillatory Ventilation in a Model of Meconium Aspiration Syndrome. ( 26017729 )
2015
31
Histologic Evidence of Intrapulmonary Bronchopulmonary Anastomotic Pathways in Neonates with Meconium Aspiration Syndrome. ( 26421487 )
2015
32
Effect of intrapartum oropharyngeal (IP-OP) suction on meconium aspiration syndrome (MAS) in developing country: A RCT. ( 26449871 )
2015
33
Surfactant with and without bronchoalveolar lavage in an experimental model of meconium aspiration syndrome. ( 25719289 )
2015
34
Surfactant for meconium aspiration syndrome in term and late preterm infants. ( 25504256 )
2014
35
N-acetylcysteine advancement of surfactant therapy in experimental meconium aspiration syndrome: possible mechanisms. ( 25669694 )
2014
36
Predictors of mortality in neonates with meconium aspiration syndrome. ( 25128992 )
2014
37
Secreted phospholipase A2 is increased in meconium-stained amniotic fluid of term gestations: potential implications for the genesis of meconium aspiration syndrome. ( 24063538 )
2014
38
Blood lactate level and meconium aspiration syndrome. ( 25256123 )
2014
39
Lung ultrasound findings in meconium aspiration syndrome. ( 25220126 )
2014
40
Predictors of mortality in neonates with meconium aspiration syndrome. ( 25128996 )
2014
41
Changes in Mean Arterial Blood Pressure During Sildenafil Use in Neonates With Meconium Aspiration Syndrome or Sepsis. ( 23344111 )
2013
42
High Asparatate Aminotransferase Level Predicts Poor Neurodevelopmental Outcome in Infants with Meconium Aspiration Syndrome. ( 24347255 )
2013
43
Spectrophotometric analysis in umbilical cords of infants with meconium aspiration syndrome. ( 23743814 )
2013
44
How to overcome surfactant dysfunction in meconium aspiration syndrome? ( 23473924 )
2013
45
A Case of Meconium Aspiration Syndrome in a Bottlenose Dolphin (Tursiops truncatus) Calf. ( 23966011 )
2013
46
Lung lavage for meconium aspiration syndrome in newborn infants. ( 23633311 )
2013
47
Anti-inflammatory treatment of meconium aspiration syndrome: benefits and risks. ( 23466955 )
2013
48
Effects of Natural versus Synthetic Surfactant with SP-B and SP-C Analogs in a Porcine Model of Meconium Aspiration Syndrome. ( 24356240 )
2013
49
Fluid recovery during lung lavage in meconium aspiration syndrome. ( 23194445 )
2013
50
Budesonide added to modified porcine surfactant Curosurf may additionally improve the lung functions in meconium aspiration syndrome. ( 24329699 )
2013

Variations for Meconium Aspiration Syndrome

Expression for Meconium Aspiration Syndrome

Search GEO for disease gene expression data for Meconium Aspiration Syndrome.

Pathways for Meconium Aspiration Syndrome

Pathways related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.51 CSF2 CXCL8 EDN1 IFNG IL6 TNF
2
Show member pathways
13.21 CSF2 CXCL8 IFNG IL6 TNF
3
Show member pathways
12.87 CXCL8 IFNG IL6 TNF
4
Show member pathways
12.75 CXCL8 IFNG IL6 TNF
5
Show member pathways
12.67 CXCL8 IFNG IL6 TNF
6
Show member pathways
12.64 CXCL8 IFNG IL6 TNF
7
Show member pathways
12.52 CSF2 CXCL8 IFNG IL6 TNF
8
Show member pathways
12.47 CSF2 CXCL8 IL6 TNF
9
Show member pathways
12.35 CSF2 IFNG IL6 TNF
10 12.3 CSF2 IL6 TNF
11
Show member pathways
12.22 IFNG IL6 TNF
12
Show member pathways
12.2 CXCL8 IFNG IL6 TNF
13
Show member pathways
12.16 CXCL8 IL6 TNF
14
Show member pathways
12.16 CXCL8 EDN1 IL6 TNF
15
Show member pathways
12.16 CSF2 CXCL8 IFNG IL6 TNF
16
Show member pathways
12.15 IFNG IL6 TNF
17 12.14 CSF2 CXCL8 IL6
18 12.12 IFNG IL6 TNF
19
Show member pathways
12.12 CXCL8 IFNG IL6 TNF
20 12.08 IFNG IL6 TNF
21 12.07 CXCL8 IL6 TNF
22 11.99 EDN1 IFNG TNF
23 11.96 CXCL8 IFNG IL6 TNF
24 11.93 CSF2 IFNG IL6 TNF
25 11.9 CXCL8 IL6 TNF
26 11.89 CSF2 EDN1 IL6 TNF
27 11.86 CXCL8 IFNG IL6
28 11.83 EDN1 IFNG IL6
29 11.83 CXCL8 EDN1 IL6 TNF
30 11.82 CSF2 IL6 TNF
31
Show member pathways
11.8 CSF2 CXCL8 IL6
32 11.75 CSF2 CXCL8 IFNG IL6
33 11.71 CSF2 CXCL8 IFNG IL6
34 11.7 CXCL8 IL6 TNF
35
Show member pathways
11.66 CSF2 CXCL8 IFNG TNF
36 11.64 CSF2 CXCL8 IFNG IL6 TNF
37 11.63 CSF2 IFNG IL6 TNF
38 11.55 CXCL8 IFNG IL6
39 11.54 CXCL8 IL6 TNF
40 11.51 IFNG IL6 TNF
41 11.51 CSF2 CXCL8 IFNG IL6 TNF
42 11.45 IFNG IL6 TNF
43 11.4 CSF2 CXCL8 IL6 TNF
44 11.36 CXCL8 IFNG IL6 TNF
45 11.31 IFNG IL6 TNF
46 11.27 IFNG IL6 TNF
47 11.26 IL6 TNF
48 11.25 CXCL8 IL6
49 11.23 CSF2 CXCL8
50 11.2 IL6 TNF

GO Terms for Meconium Aspiration Syndrome

Cellular components related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 CSF2 CXCL8 EDN1 IFNG IL6 SCGB1A1
2 extracellular space GO:0005615 9.23 CSF2 CXCL8 EDN1 IFNG IL6 SCGB1A1

Biological processes related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

(show all 37)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.93 CSF2 EDN1 IFNG IL6
2 positive regulation of gene expression GO:0010628 9.88 CSF2 IFNG IL6 TNF
3 cytokine-mediated signaling pathway GO:0019221 9.87 CSF2 CXCL8 IL6 TNF
4 regulation of cell proliferation GO:0042127 9.85 CSF2 CXCL8 TNF
5 positive regulation of DNA binding transcription factor activity GO:0051091 9.77 EDN1 IL6 TNF
6 immune response GO:0006955 9.77 CSF2 CXCL8 IFNG IL6 TNF
7 response to lipopolysaccharide GO:0032496 9.73 CPS1 CXCL8 EDN1 SCGB1A1
8 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.72 CSF2 IFNG IL6
9 humoral immune response GO:0006959 9.69 IFNG IL6 TNF
10 positive regulation of JUN kinase activity GO:0043507 9.67 EDN1 TNF
11 respiratory gaseous exchange GO:0007585 9.67 EDN1 SFTPB
12 positive regulation of smooth muscle cell proliferation GO:0048661 9.67 EDN1 IL6 TNF
13 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.66 CSF2 TNF
14 response to amino acid GO:0043200 9.66 CPS1 EDN1
15 cellular response to fibroblast growth factor stimulus GO:0044344 9.65 CPS1 CXCL8
16 positive regulation of neutrophil chemotaxis GO:0090023 9.65 CXCL8 EDN1
17 protein import into nucleus, translocation GO:0000060 9.65 IFNG TNF
18 positive regulation of protein complex assembly GO:0031334 9.64 IFNG TNF
19 positive regulation of leukocyte chemotaxis GO:0002690 9.64 CXCL8 IL6
20 positive regulation of osteoclast differentiation GO:0045672 9.63 IFNG TNF
21 positive regulation of chemokine production GO:0032722 9.62 IL6 TNF
22 embryonic digestive tract development GO:0048566 9.62 CXCL8 TNF
23 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.61 IFNG TNF
24 response to dexamethasone GO:0071548 9.61 CPS1 EDN1
25 positive regulation of podosome assembly GO:0071803 9.6 CSF2 TNF
26 negative regulation of lipid storage GO:0010888 9.58 IL6 TNF
27 positive regulation of nitric oxide biosynthetic process GO:0045429 9.58 EDN1 IFNG TNF
28 epithelial fluid transport GO:0042045 9.56 CSF2 EDN1
29 positive regulation of interleukin-23 production GO:0032747 9.54 CSF2 IFNG
30 response to ozone GO:0010193 9.52 EDN1 SCGB1A1
31 histamine secretion GO:0001821 9.48 CSF2 EDN1
32 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.46 IFNG TNF
33 cellular response to lipopolysaccharide GO:0071222 9.46 CSF2 CXCL8 IL6 TNF
34 positive regulation of vitamin D biosynthetic process GO:0060557 9.32 IFNG TNF
35 response to silicon dioxide GO:0034021 9.26 CSF2 SCGB1A1
36 response to glucocorticoid GO:0051384 9.26 CPS1 IL6 SCGB1A1 TNF
37 regulation of signaling receptor activity GO:0010469 9.1 CSF2 CXCL8 EDN1 IFNG IL6 TNF

Molecular functions related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.1 CSF2 CXCL8 EDN1 IFNG IL6 TNF

Sources for Meconium Aspiration Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....