MCID: MDN001
MIFTS: 26

Median Rhomboid Glossitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Median Rhomboid Glossitis

MalaCards integrated aliases for Median Rhomboid Glossitis:

Name: Median Rhomboid Glossitis 12 15 32
Persistent Tuberculum Impar 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14111
ICD9CM 34 529.2
SNOMED-CT 67 7522008
ICD10 32 K14.2
UMLS 71 C0155963

Summaries for Median Rhomboid Glossitis

MalaCards based summary : Median Rhomboid Glossitis, also known as persistent tuberculum impar, is related to fissured tongue and glossitis. An important gene associated with Median Rhomboid Glossitis is KRT6A (Keratin 6A), and among its related pathways/superpathways are Developmental Biology and Cytoskeletal Signaling. Affiliated tissues include tongue, salivary gland and skin.

Wikipedia : 74 Median rhomboid glossitis is a condition characterized by an area of redness and loss of lingual... more...

Related Diseases for Median Rhomboid Glossitis

Graphical network of the top 20 diseases related to Median Rhomboid Glossitis:



Diseases related to Median Rhomboid Glossitis

Symptoms & Phenotypes for Median Rhomboid Glossitis

Drugs & Therapeutics for Median Rhomboid Glossitis

Search Clinical Trials , NIH Clinical Center for Median Rhomboid Glossitis

Genetic Tests for Median Rhomboid Glossitis

Anatomical Context for Median Rhomboid Glossitis

MalaCards organs/tissues related to Median Rhomboid Glossitis:

40
Tongue, Salivary Gland, Skin

Publications for Median Rhomboid Glossitis

Articles related to Median Rhomboid Glossitis:

(show top 50) (show all 109)
# Title Authors PMID Year
1
Genetic and developmental disorders of the oral mucosa: Epidemiology; molecular mechanisms; diagnostic criteria; management. 61
31090139 2019
2
Candidiasis: Red and White Manifestations in the Oral Cavity. 61
30693459 2019
3
Prevalence of Oral Candidiasis in Indian HIV Sero-Positive Patients with CD4+ Cell Count Correlation. 61
30906728 2019
4
Oral Fungal Microbiota: To Thrush and Beyond. 61
31768404 2019
5
Prevalence of Dental Enamel Defects, Aphthous-Like Ulcers and Other Oral Manifestations in Celiac Children and Adolescents: A Comparative Study. 61
31283894 2019
6
Characteristics of lingual papillae in diabetic rats. 61
30219545 2018
7
Update from the 4th Edition of the World Health Organization of Head and Neck Tumours: Tumours of the Oral Cavity and Mobile Tongue. 61
28247230 2017
8
Perception of iron deficiency from oral mucosa alterations that show a high prevalence of Candida infection. 61
27133388 2016
9
Oral mucosal lesions in older people: relation to salivary secretion, systemic diseases and medications. 61
25754744 2015
10
Impact of oral mucosal conditions on oral health-related quality of life in preschool children: a hierarchical approach. 61
24730747 2015
11
Median rhomboid glossitis-developmental or candidal? 61
26523164 2015
12
[A woman with a red demarcation of the tongue]. 61
26246064 2015
13
Application of the novel method in the diagnosis and treatment of median rhomboid glossitis Candida-associated. 61
24966760 2014
14
Diagnostic discussion. Median rhomboid glossitis (MRG). 61
24579425 2013
15
Langerhans cells and their role in oral mucosal diseases. 61
24251267 2013
16
Prevalence of oral mucosal lesions in dental patients with tobacco smoking, chewing, and mixed habits: A cross-sectional study in South India. 61
23983566 2013
17
Urban legends series: oral candidosis. 61
22998462 2013
18
Oral findings of rothmund-thomson syndrome. 61
24363941 2013
19
Tongue lesions in a Jordanian population. Prevalence, symptoms, subject's knowledge and treatment provided. 61
21196841 2011
20
Median rhomboid glossitis: a clinical and microbiological study. 61
21912494 2011
21
The prevalence of median rhomboid glossitis in diabetic patients: a case-control study. 61
22737518 2011
22
The prevalence of tongue lesions in Malaysian dental outpatients from the Klang Valley area. 61
20796228 2011
23
Median rhomboid glossitis. 61
21446620 2011
24
Common tongue conditions in primary care. 61
20187599 2010
25
Hyperplastic candidosis on the palate developed as a 'kissing' lesion from median rhomboid glossitis. 61
20339702 2010
26
A classic case of median rhomboid glossitis. 61
19601454 2009
27
Evaluation of oral mucosal lesions in 598 referred Iranian patients. 61
19444343 2009
28
The prevalence of oral mucosal lesions in adults from the Turin area. 61
18410578 2008
29
The prevalence of oral mucosal lesions in patients visiting a dental school in Southern India. 61
18445924 2008
30
Median rhomboid glossitis. 61
17990677 2007
31
Partial atrophic tongue other than median rhomboid glossitis. 61
17441970 2007
32
Pachyonychia congenita associated with median rhomboid glossitis. 61
17511954 2007
33
Diagnostic quiz. Case No. 1: median rhomboid glossitis. 61
17632961 2006
34
Prevalence of tongue lesions among Turkish schoolchildren. 61
16380783 2005
35
Oral candidosis and the therapeutic use of antifungal agents in dentistry. 61
16416716 2005
36
Atrophic tongue associated with Candida. 61
16011607 2005
37
Rhomboid glossitis in atypical location: case report and differential diagnosis. 61
15735544 2005
38
[Median rhomboid glossitis--change of inflammation origin or developmental anomaly?]. 61
16521451 2005
39
Kaposi's sarcoma of the tongue associated with median rhomboid glossitis in a non-AIDS patient. A case report. 61
15274372 2004
40
Prevalence of fissured tongue, geographic tongue and median rhomboid glossitis among Israeli adults of different ethnic origins. 61
15316160 2004
41
Prevalence of oral mucosal lesions in elderly people in Santiago, Chile. 61
14632931 2003
42
A case of median rhomboid glossitis. 61
12773811 2003
43
Prevalence of oral lesions and percent CD4+ T-lymphocytes in HIV-infected children on antiretroviral therapy. 61
12614515 2003
44
Oral pathology quiz #2. Median rhomboid glossitis. 61
11808366 2001
45
Insulin-dependent diabetes mellitus and oral soft tissue pathologies: II. Prevalence and characteristics of Candida and Candidal lesions. 61
10807713 2000
46
Insulin-dependent diabetes mellitus and oral soft tissue pathologies. I. Prevalence and characteristics of non-candidal lesions. 61
10807712 2000
47
Oral soft tissue manifestations in HIV-positive vs. HIV-negative children from an inner city population: a two-year observational study. 61
10846732 2000
48
Oral candidiasis in children with immune suppression: clinical appearance and therapeutic considerations. 61
10476353 1999
49
The frequency of fungal infection in biopsies of oral mucosal lesions. 61
9655041 1998
50
Localized amyloid tumor of the tongue. A case report and review of the literature. 61
15678860 1998

Variations for Median Rhomboid Glossitis

Expression for Median Rhomboid Glossitis

Search GEO for disease gene expression data for Median Rhomboid Glossitis.

Pathways for Median Rhomboid Glossitis

Pathways related to Median Rhomboid Glossitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.83 KRT6B KRT6A KRT17 KRT16
2 11.82 KRT6B KRT6A KRT17
3
Show member pathways
11.38 KRT6B KRT6A KRT17 KRT16
4 11.24 KRT17 KRT16
5
Show member pathways
11.17 KRT6A KRT17 KRT16

GO Terms for Median Rhomboid Glossitis

Cellular components related to Median Rhomboid Glossitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratin filament GO:0045095 8.96 KRT6B KRT6A
2 intermediate filament GO:0005882 8.92 KRT6B KRT6A KRT17 KRT16

Biological processes related to Median Rhomboid Glossitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoskeleton organization GO:0007010 9.33 KRT6B KRT6A KRT16
2 morphogenesis of an epithelium GO:0002009 9.26 KRT6A KRT16
3 keratinization GO:0031424 9.26 KRT6B KRT6A KRT17 KRT16
4 cornification GO:0070268 8.92 KRT6B KRT6A KRT17 KRT16

Molecular functions related to Median Rhomboid Glossitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.92 KRT6B KRT6A KRT17 KRT16

Sources for Median Rhomboid Glossitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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