Mediastinum Sarcoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Mediastinum Sarcoma

MalaCards integrated aliases for Mediastinum Sarcoma:

Name: Mediastinum Sarcoma ¹²

Sarcoma of Mediastinum ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:4050

NCIt ⁴⁹ C6606

UMLS ⁷¹ C1334678

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Summaries for Mediastinum Sarcoma

Disease Ontology : ¹² A sarcoma and malignant mediastinal mesenchymnal tumor that is located in the mediastinum.

MalaCards based summary : Mediastinum Sarcoma, also known as sarcoma of mediastinum, is related to mediastinum synovial sarcoma and sarcoma. The drugs Celecoxib and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include mediastinum and lung.

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Related Diseases for Mediastinum Sarcoma

Diseases related to Mediastinum Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score
1	mediastinum synovial sarcoma	11.4
2	sarcoma	10.0
3	spindle cell sarcoma	10.0
4	leukemia, acute myeloid	9.9
5	myelodysplastic syndrome	9.9
6	follicular dendritic cell sarcoma	9.9
7	myeloid sarcoma	9.9
8	myeloid leukemia	9.9
9	soft tissue sarcoma	9.9

Graphical network of the top 20 diseases related to Mediastinum Sarcoma:

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Symptoms & Phenotypes for Mediastinum Sarcoma

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Drugs & Therapeutics for Mediastinum Sarcoma

Drugs for Mediastinum Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Celecoxib

Approved, Investigational

Phase 1, Phase 2

169590-42-5

2662

Synonyms:

169590-42-5

184007-95-2

1oq5

4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide

4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1Hpyrazol-1-yl] benzenesulfonamide

4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE

4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide

AC1L1E6K

AC-4228

AI-525

Benzenesulfonamide,4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)

BIDD:GT0408

BRD-K02637541-001-02-4

BSPBio_003596

C07589

C105934

C17H14F3N3O2S

CCRIS 8679

CEL

Celebra

Celebrex

Celebrex (TN)

Celebrex, Celebra, Celecoxib

Celecox

Celecoxi

celecoxib

Celecoxib

Célécoxib

Celecoxib (JAN/USAN/INN)

Celecoxib (SC-58635)

Celecoxib [Old RN]

Celecoxib [USAN]

Celecoxibum

Celocoxib

CEP-33222

CHEBI:41423

CHEMBL118

CID2662

cMAP_000027

CPD000550473

D00567

DB00482

DivK1c_000893

Eurocox

FT-0080064

HMS1922G14

HMS2089L18

HMS2093I07

HMS502M15

HSDB 7038

I01-1033

IDI1_000893

KBio1_000893

KBio2_000912

KBio2_002351

KBio2_003480

KBio2_004919

KBio2_006048

KBio2_007487

KBio3_002830

KBio3_003037

KBioGR_000723

KBioGR_002351

KBioSS_000912

KBioSS_002354

LS-31667

Medicoxib

MLS001165684

MLS001195656

MLS001304708

MolPort-002-885-815

NCGC00091455-01

NCGC00091455-02

NCGC00091455-03

NCGC00091455-04

NCI60_041049

NINDS_000893

NSC719627

Onsenal

p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide

P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide

P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulphonamide

Pfizer brand of celecoxib

S1261_Selleck

SAM002589995

SC 58635

SC-58553, SC-58635

SC58635

SC-58635

SMR000550473

Solexa

SPBio_001512

Spectrum_000432

SPECTRUM1503678

Spectrum2_001576

Spectrum3_001996

Spectrum4_000182

Spectrum5_001324

TL8001323

TPI-336

UNM-0000305813

Xilebao

YM 177

YM177

YM-177

ZINC02570895

2

Cyclophosphamide

Approved, Investigational

Phase 1, Phase 2

50-18-0, 6055-19-2

2907

Synonyms:

(-)-Cyclophosphamide

(+-)-Cyclophosphamide

(RS)-Cyclophosphamide

1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine

1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin

2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide

4-Hydroxy-cyclophosphan-mamophosphatide

50-18-0

60007-95-6

6055-19-2 (monohydrate)

75526-90-8

AC1L1EQQ

AI3-26198

Anhydrous cyclophosphamide

Anhydrous, cyclophosphamide

ASTA

Asta B 518

ASTA B518

B 518

B-518

bis(2-Chloroethyl)phosphami de cyclic propanolamide

bis(2-Chloroethyl)phosphamide cyclic propanolamide ester

Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester

BRN 0011744

BSPBio_002099

C 0768

C07888

C7H15Cl2N2O2P

CB 4564

CB-4564

CCRIS 188

CHEBI:4027

CHEMBL32520

CHEMBL88

Ciclofosfamida

Ciclofosfamida [INN-Spanish]

Ciclofosfamide

Ciclophosphamide

Ciclophosphamide [INN]

CID2907

Clafen

Claphene

CP

CPA

CTX

CY

Cycloblastin

Cyclophosphamid

cyclophosphamide

Cyclophosphamide

Cyclophosphamide (anhydrous form)

Cyclophosphamide (anhydrous)

Cyclophosphamide (INN)

Cyclophosphamide (TN)

Cyclophosphamide anhydrous

Cyclophosphamide monohydrate

Cyclophosphamide Monohydrate

Cyclophosphamide Sterile

Cyclophosphamide, (+-)-Isomer

Cyclophosphamide, (R)-isomer

Cyclophosphamide, (S)-isomer

Cyclophosphamides

Cyclophosphamidum

Cyclophosphamidum [INN-Latin]

Cyclophosphan

Cyclophosphane

Cyclophosphanum

Cyclophosphoramide

Cyclostin

Cyklofosfamid

Cyklofosfamid [Czech]

Cytophosphan

Cytophosphane

Cytoxan

Cytoxan (TN)

Cytoxan Lyoph

D,L-Cyclophosphamide

D07760

DB00531

DivK1c_000246

EINECS 200-015-4

Endoxan

Endoxan R

Endoxana

Endoxanal

Endoxan-Asta

Endoxane

Enduxan

EU-0100238

Genoxal

Hexadrin

HMS2090A12

HSDB 3047

IDI1_000246

KBio1_000246

KBio2_001338

KBio2_003906

KBio2_006474

KBio3_001319

KBioGR_000888

KBioSS_001338

Lopac0_000238

Lopac-C-0768

LS-1302

LS-99787

Lyophilized Cytoxan

Mitoxan

MolPort-001-783-420

Monohydrate, cyclophosphamide

N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

NCGC00015209-01

NCGC00015209-03

NCGC00015209-06

NCGC00091741-02

NCGC00091741-03

NCI60_002097

NCI-C04900

Neosar

NINDS_000246

NSC 26271

NSC26271

NSC-26271

NSC273033

NSC273034

Occupation, cyclophosphamide exposure

Procytox

RCRA waste no. U058

Rcra waste number U058

Rcra Waste Number U058

Revimmune

S1217_Selleck

Semdoxan

Sendoxan

Senduxan

SK 20501

SPBio_001071

Spectrum_000858

Spectrum2_001146

Spectrum3_000370

Spectrum4_000304

Spectrum5_000795

STK177249

STOCK2S-91217

UNII-6UXW23996M

WLN: T6MPOTJ BO BN2G2G

Zyklophosphamid

Zyklophosphamid [German]

3

Vaccines

Phase 1, Phase 2

4

Analgesics, Non-Narcotic

Phase 1, Phase 2

5

Cyclooxygenase 2 Inhibitors

Phase 1, Phase 2

6

Alkylating Agents

Phase 1, Phase 2

7

Immunosuppressive Agents

Phase 1, Phase 2

8

Analgesics

Phase 1, Phase 2

9

Cyclooxygenase Inhibitors

Phase 1, Phase 2

10

Immunologic Factors

Phase 1, Phase 2

11

Antirheumatic Agents

Phase 1, Phase 2

12

Anti-Inflammatory Agents

Phase 1, Phase 2

13

Anti-Inflammatory Agents, Non-Steroidal

Phase 1, Phase 2

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum	Suspended	NCT02054104	Phase 1, Phase 2	Cyclophosphamide;Celecoxib

Search NIH Clinical Center for Mediastinum Sarcoma

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Genetic Tests for Mediastinum Sarcoma

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Anatomical Context for Mediastinum Sarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Mediastinum Sarcoma:

¹⁹

Mediastinum

MalaCards organs/tissues related to Mediastinum Sarcoma:

⁴⁰

Lung

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Publications for Mediastinum Sarcoma

Articles related to Mediastinum Sarcoma:

#	Title	Authors	PMID	Year
1	Follicular dendritic cell sarcoma of mediastinum: a key role of radiotherapy in a multidisciplinary approach. ⁶¹	Spatola C...Privitera G	26638926	2015
2	[Primary soft tissue sarcomas of mediastinum: experience in 22 cases from a single institution]. ⁶¹	Mu JW...He J	18642788	2008
3	Myelodysplasia presenting as granulocytic sarcoma of mediastinum causing superior vena cava syndrome. ⁶¹	Ravandi-Kashani F...Giles FJ	10784409	2000

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Genes for Mediastinum Sarcoma

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Variations for Mediastinum Sarcoma

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Expression for Mediastinum Sarcoma

Search GEO for disease gene expression data for Mediastinum Sarcoma.

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Pathways for Mediastinum Sarcoma

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GO Terms for Mediastinum Sarcoma

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Sources for Mediastinum Sarcoma

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