MCID: MDS023
MIFTS: 14

Mediastinum Sarcoma

Categories: Cancer diseases

Aliases & Classifications for Mediastinum Sarcoma

MalaCards integrated aliases for Mediastinum Sarcoma:

Name: Mediastinum Sarcoma 12
Sarcoma of Mediastinum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4050
NCIt 49 C6606
UMLS 71 C1334678

Summaries for Mediastinum Sarcoma

Disease Ontology : 12 A sarcoma and malignant mediastinal mesenchymnal tumor that is located in the mediastinum.

MalaCards based summary : Mediastinum Sarcoma, also known as sarcoma of mediastinum, is related to mediastinum synovial sarcoma and sarcoma. The drugs Celecoxib and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include mediastinum and lung.

Related Diseases for Mediastinum Sarcoma

Diseases related to Mediastinum Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 mediastinum synovial sarcoma 11.4
2 sarcoma 10.0
3 spindle cell sarcoma 10.0
4 leukemia, acute myeloid 9.9
5 myelodysplastic syndrome 9.9
6 follicular dendritic cell sarcoma 9.9
7 myeloid sarcoma 9.9
8 myeloid leukemia 9.9
9 soft tissue sarcoma 9.9

Graphical network of the top 20 diseases related to Mediastinum Sarcoma:



Diseases related to Mediastinum Sarcoma

Symptoms & Phenotypes for Mediastinum Sarcoma

Drugs & Therapeutics for Mediastinum Sarcoma

Drugs for Mediastinum Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Celecoxib Approved, Investigational Phase 1, Phase 2 169590-42-5 2662
2
Cyclophosphamide Approved, Investigational Phase 1, Phase 2 50-18-0, 6055-19-2 2907
3 Vaccines Phase 1, Phase 2
4 Analgesics, Non-Narcotic Phase 1, Phase 2
5 Cyclooxygenase 2 Inhibitors Phase 1, Phase 2
6 Alkylating Agents Phase 1, Phase 2
7 Immunosuppressive Agents Phase 1, Phase 2
8 Analgesics Phase 1, Phase 2
9 Cyclooxygenase Inhibitors Phase 1, Phase 2
10 Immunologic Factors Phase 1, Phase 2
11 Antirheumatic Agents Phase 1, Phase 2
12 Anti-Inflammatory Agents Phase 1, Phase 2
13 Anti-Inflammatory Agents, Non-Steroidal Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum Suspended NCT02054104 Phase 1, Phase 2 Cyclophosphamide;Celecoxib

Search NIH Clinical Center for Mediastinum Sarcoma

Genetic Tests for Mediastinum Sarcoma

Anatomical Context for Mediastinum Sarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Mediastinum Sarcoma:

19
Mediastinum

MalaCards organs/tissues related to Mediastinum Sarcoma:

40
Lung

Publications for Mediastinum Sarcoma

Articles related to Mediastinum Sarcoma:

# Title Authors PMID Year
1
Follicular dendritic cell sarcoma of mediastinum: a key role of radiotherapy in a multidisciplinary approach. 61
26638926 2015
2
[Primary soft tissue sarcomas of mediastinum: experience in 22 cases from a single institution]. 61
18642788 2008
3
Myelodysplasia presenting as granulocytic sarcoma of mediastinum causing superior vena cava syndrome. 61
10784409 2000

Variations for Mediastinum Sarcoma

Expression for Mediastinum Sarcoma

Search GEO for disease gene expression data for Mediastinum Sarcoma.

Pathways for Mediastinum Sarcoma

GO Terms for Mediastinum Sarcoma

Sources for Mediastinum Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....