MCID: MDS010
MIFTS: 14

Mediastinum Seminoma

Categories: Cancer diseases

Aliases & Classifications for Mediastinum Seminoma

MalaCards integrated aliases for Mediastinum Seminoma:

Name: Mediastinum Seminoma 12 15
Seminoma of Mediastinum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6249
NCIt 49 C6812
UMLS 71 C1334680

Summaries for Mediastinum Seminoma

MalaCards based summary : Mediastinum Seminoma, also known as seminoma of mediastinum, is related to teratoma and embryonal carcinoma. An important gene associated with Mediastinum Seminoma is ZNHIT2 (Zinc Finger HIT-Type Containing 2), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers and Mesenchymal Stem Cells and Lineage-specific Markers.

Related Diseases for Mediastinum Seminoma

Diseases related to Mediastinum Seminoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 teratoma 29.7 KIT AFP
2 embryonal carcinoma 29.6 KIT AFP
3 seminoma 29.4 KIT ALPP AFP
4 choriocarcinoma 10.0
5 hepatic tuberculosis 9.9 ALPP AFP
6 sex cord-gonadal stromal tumor 9.8 ALPP AFP
7 sertoli cell tumor 9.8 ALPP AFP
8 mixed germ cell tumor 9.8 KIT AFP
9 extragonadal seminoma 9.8 KIT AFP
10 pineal region teratoma 9.8 KIT AFP
11 gallbladder leiomyosarcoma 9.8 KIT AFP
12 liver leiomyoma 9.8 KIT AFP
13 intratubular embryonal carcinoma 9.8 KIT AFP
14 mixed germ cell cancer 9.8 KIT AFP
15 ovarian mixed germ cell neoplasm 9.8 KIT AFP
16 hepatic angiomyolipoma 9.8 KIT AFP
17 angiomyolipoma 9.8 KIT AFP
18 dysgerminoma of ovary 9.7 KIT AFP
19 liver leiomyosarcoma 9.7 KIT AFP
20 ovarian gonadoblastoma 9.7 KIT AFP
21 sarcomatous intrahepatic cholangiocarcinoma 9.7 KIT AFP
22 endometrial small cell carcinoma 9.7 KIT AFP
23 brain germinoma 9.7 KIT AFP
24 spermatocytoma 9.7 KIT AFP
25 mediastinal cancer 9.7 KIT AFP
26 ovarian germ cell cancer 9.7 KIT AFP
27 malignant teratoma 9.7 KIT AFP
28 mature teratoma 9.7 KIT AFP
29 endodermal sinus tumor 9.7 KIT AFP
30 gonadoblastoma 9.7 KIT ALPP
31 mixed cell type cancer 9.7 KIT AFP
32 cystic teratoma 9.6 KIT AFP
33 cavernous hemangioma 9.6 KIT AFP
34 cystadenoma 9.6 KIT AFP
35 testicular cancer 9.6 ALPP AFP
36 germ cell and embryonal cancer 9.6 KIT AFP
37 testicular disease 9.5 KIT AFP
38 obstructive jaundice 9.5 KIT ALPP
39 waardenburg's syndrome 9.4 KIT ALPP
40 cryptorchidism, unilateral or bilateral 9.4 KIT AFP
41 germinoma 9.3 KIT ALPP AFP
42 dysgerminoma 9.3 KIT ALPP AFP
43 testicular germ cell tumor 9.3 KIT ALPP AFP
44 germ cell cancer 9.3 KIT ALPP AFP
45 wilms tumor 1 9.2 KIT AFP

Graphical network of the top 20 diseases related to Mediastinum Seminoma:



Diseases related to Mediastinum Seminoma

Symptoms & Phenotypes for Mediastinum Seminoma

Drugs & Therapeutics for Mediastinum Seminoma

Search Clinical Trials , NIH Clinical Center for Mediastinum Seminoma

Genetic Tests for Mediastinum Seminoma

Anatomical Context for Mediastinum Seminoma

Publications for Mediastinum Seminoma

Articles related to Mediastinum Seminoma:

# Title Authors PMID Year
1
Mixed germ cell tumour of the mediastinum (seminoma, embryonal carcinoma, choriocarcinoma and teratoma). Light and electron microscopic cytology and histological investigation. 61
2557596 1989

Variations for Mediastinum Seminoma

Expression for Mediastinum Seminoma

Search GEO for disease gene expression data for Mediastinum Seminoma.

Pathways for Mediastinum Seminoma

Pathways related to Mediastinum Seminoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.08 ALPP AFP
2 10.6 KIT ALPP

GO Terms for Mediastinum Seminoma

Molecular functions related to Mediastinum Seminoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 8.92 ZNHIT2 KIT ALPP AFP

Sources for Mediastinum Seminoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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