MCID: MDS010
MIFTS: 13

Mediastinum Seminoma

Categories: Cancer diseases

Aliases & Classifications for Mediastinum Seminoma

MalaCards integrated aliases for Mediastinum Seminoma:

Name: Mediastinum Seminoma 12 15
Seminoma of Mediastinum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6249
NCIt 50 C6812
UMLS 71 C1334680

Summaries for Mediastinum Seminoma

MalaCards based summary : Mediastinum Seminoma, also known as seminoma of mediastinum, is related to teratoma and embryonal carcinoma. An important gene associated with Mediastinum Seminoma is ALPP (Alkaline Phosphatase, Placental), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers.

Related Diseases for Mediastinum Seminoma

Diseases related to Mediastinum Seminoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
# Related Disease Score Top Affiliating Genes
1 teratoma 29.7 KIT AFP
2 embryonal carcinoma 29.7 KIT AFP
3 seminoma 29.2 KIT ALPP AFP
4 choriocarcinoma 9.9
5 hepatic tuberculosis 9.9 ALPP AFP
6 sertoli-leydig cell tumor 9.9 ALPP AFP
7 sex cord-gonadal stromal tumor 9.9 ALPP AFP
8 sertoli cell tumor 9.9 ALPP AFP
9 endodermal sinus tumor 9.9 ALPP AFP
10 mixed germ cell tumor 9.9 KIT AFP
11 extragonadal seminoma 9.9 KIT AFP
12 pineal region teratoma 9.9 KIT AFP
13 gallbladder leiomyosarcoma 9.9 KIT AFP
14 liver leiomyoma 9.9 KIT AFP
15 intratubular embryonal carcinoma 9.9 KIT AFP
16 esophageal adenoid cystic carcinoma 9.8 KIT AFP
17 mixed germ cell cancer 9.8 KIT AFP
18 ovarian mixed germ cell neoplasm 9.8 KIT AFP
19 sarcomatous intrahepatic cholangiocarcinoma 9.8 KIT AFP
20 endometrial small cell carcinoma 9.8 KIT AFP
21 ovarian gonadoblastoma 9.8 KIT AFP
22 liver leiomyosarcoma 9.8 KIT AFP
23 brain germinoma 9.8 KIT AFP
24 mediastinal cancer 9.8 KIT AFP
25 malignant teratoma 9.8 KIT AFP
26 seminal vesicle adenocarcinoma 9.8 KIT AFP
27 spermatocytoma 9.8 KIT AFP
28 mature teratoma 9.8 KIT AFP
29 leydig cell tumor 9.8 KIT AFP
30 mixed cell type cancer 9.8 KIT AFP
31 gonadoblastoma 9.8 KIT ALPP
32 cystadenoma 9.8 KIT AFP
33 germ cell and embryonal cancer 9.8 KIT AFP
34 testicular germ cell tumor 9.7 KIT AFP
35 testicular cancer 9.7 ALPP AFP
36 testicular disease 9.7 KIT AFP
37 obstructive jaundice 9.7 KIT ALPP
38 blood coagulation disease 9.7 KIT AFP
39 gastric adenocarcinoma 9.7 KIT AFP
40 waardenburg's syndrome 9.7 KIT ALPP
41 hemorrhagic disease 9.6 KIT AFP
42 liver cirrhosis 9.6 ALPP AFP
43 dysgerminoma 9.5 KIT ALPP AFP
44 dysgerminoma of ovary 9.5 KIT ALPP AFP
45 germinoma 9.5 KIT ALPP AFP
46 germ cell cancer 9.5 KIT ALPP AFP
47 cryptorchidism, unilateral or bilateral 9.5 KIT ALPP AFP

Graphical network of the top 20 diseases related to Mediastinum Seminoma:



Diseases related to Mediastinum Seminoma

Symptoms & Phenotypes for Mediastinum Seminoma

Drugs & Therapeutics for Mediastinum Seminoma

Search Clinical Trials , NIH Clinical Center for Mediastinum Seminoma

Genetic Tests for Mediastinum Seminoma

Anatomical Context for Mediastinum Seminoma

Publications for Mediastinum Seminoma

Articles related to Mediastinum Seminoma:

# Title Authors PMID Year
1
Mixed germ cell tumour of the mediastinum (seminoma, embryonal carcinoma, choriocarcinoma and teratoma). Light and electron microscopic cytology and histological investigation. 61
2557596 1989

Variations for Mediastinum Seminoma

Expression for Mediastinum Seminoma

Search GEO for disease gene expression data for Mediastinum Seminoma.

Pathways for Mediastinum Seminoma

Pathways related to Mediastinum Seminoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.08 ALPP AFP
2 10.6 KIT ALPP

GO Terms for Mediastinum Seminoma

Sources for Mediastinum Seminoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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