MCID: MLN064
MIFTS: 22

Melanoma of Soft Tissue

Categories: Rare diseases, Skin diseases, Muscle diseases, Cancer diseases

Aliases & Classifications for Melanoma of Soft Tissue

MalaCards integrated aliases for Melanoma of Soft Tissue:

Name: Melanoma of Soft Tissue 59
Clear Cell Sarcoma of the Tendons and Aponeuroses 59

Classifications:



External Ids:

Orphanet 59 ORPHA97338
UMLS via Orphanet 74 C0206651

Summaries for Melanoma of Soft Tissue

MalaCards based summary : Melanoma of Soft Tissue, also known as clear cell sarcoma of the tendons and aponeuroses, is related to clear cell sarcoma and melanoma. An important gene associated with Melanoma of Soft Tissue is EWSR1 (EWS RNA Binding Protein 1), and among its related pathways/superpathways are Myometrial Relaxation and Contraction Pathways and HTLV-I infection.

Wikipedia : 76 Clear-cell sarcoma (formerly known as malignant melanoma of the soft parts) is a rare form of cancer... more...

Related Diseases for Melanoma of Soft Tissue

Diseases related to Melanoma of Soft Tissue via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 clear cell sarcoma 30.5 ATF1 CREB1 EWSR1
2 melanoma 10.1
3 sarcoma 10.0
4 sarcomatosis 9.7 ATF1 EWSR1
5 human t-cell leukemia virus type 1 9.3 ATF1 CREB1
6 myxoid liposarcoma 9.2 ATF1 EWSR1
7 lung sarcoma 9.1 CREB1 EWSR1
8 fibrous histiocytoma 8.8 ATF1 CREB1 EWSR1
9 histiocytoma 8.7 ATF1 CREB1 EWSR1

Graphical network of the top 20 diseases related to Melanoma of Soft Tissue:



Diseases related to Melanoma of Soft Tissue

Symptoms & Phenotypes for Melanoma of Soft Tissue

Drugs & Therapeutics for Melanoma of Soft Tissue

Search Clinical Trials , NIH Clinical Center for Melanoma of Soft Tissue

Genetic Tests for Melanoma of Soft Tissue

Anatomical Context for Melanoma of Soft Tissue

Publications for Melanoma of Soft Tissue

Articles related to Melanoma of Soft Tissue:

# Title Authors Year
1
Lessons to be learned: a case study approach. Malignant melanoma of soft tissue. ( 15712852 )
2005
2
Malignant melanoma of soft tissues (clear cell sarcoma) of the foot. Is MRI able to perform a specific diagnosis? Report of one case and review of the radiological literature. ( 11268490 )
2000
3
Cytodiagnosis of malignant melanoma of soft tissue: report of a case with diagnosis by intraoperative cytology. ( 9755678 )
1998
4
Febrile arthritis as the first manifestation of clear cell sarcoma of the tendons and aponeuroses. ( 9809366 )
1998
5
Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft tissue). A case report. ( 2149419 )
1990
6
Ultrastructural similarities and differences of synovial sarcoma, epithelioid sarcoma, and clear cell sarcoma of the tendons and aponeuroses. ( 6087526 )
1984
7
Clear cell sarcoma of tendons and aponeuroses: malignant melanoma of soft tissues? Report of four cases. ( 556273 )
1979

Variations for Melanoma of Soft Tissue

Expression for Melanoma of Soft Tissue

Search GEO for disease gene expression data for Melanoma of Soft Tissue.

Pathways for Melanoma of Soft Tissue

GO Terms for Melanoma of Soft Tissue

Cellular components related to Melanoma of Soft Tissue according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription factor complex GO:0005667 8.62 ATF1 CREB1

Molecular functions related to Melanoma of Soft Tissue according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.33 ATF1 CREB1 EWSR1
2 RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 9.32 ATF1 CREB1
3 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0001228 9.26 ATF1 CREB1
4 transcription coregulator activity GO:0003712 8.96 CREB1 EWSR1
5 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705 8.62 ATF1 CREB1

Sources for Melanoma of Soft Tissue

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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