MCID: MLN004
MIFTS: 26

Melanotic Medulloblastoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Melanotic Medulloblastoma

MalaCards integrated aliases for Melanotic Medulloblastoma:

Name: Melanotic Medulloblastoma 12 15 73
Medulloblastoma, Melanotic 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3868
MeSH 44 D008527
NCIt 50 C9497
SNOMED-CT 68 83217000
UMLS 73 C1275668

Summaries for Melanotic Medulloblastoma

MalaCards based summary : Melanotic Medulloblastoma, also known as medulloblastoma, melanotic, is related to medulloblastoma and chordoma, and has symptoms including vomiting, gait ataxia and headache. An important gene associated with Melanotic Medulloblastoma is EPPK1 (Epiplakin 1), and among its related pathways/superpathways is Cytoskeleton remodeling Neurofilaments. Affiliated tissues include lung, brain and kidney.

Related Diseases for Melanotic Medulloblastoma

Diseases related to Melanotic Medulloblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 105)
# Related Disease Score Top Affiliating Genes
1 medulloblastoma 30.5 ENO2 GFAP SMARCB1
2 chordoma 10.1 GFAP SMARCB1
3 rhabdoid meningioma 10.1 GFAP SMARCB1
4 nodular medulloblastoma 10.1 GFAP SMARCB1
5 myoepithelioma 10.1 GFAP SMARCB1
6 pleomorphic xanthoastrocytoma 10.1 GFAP SMARCB1
7 tanycytic ependymoma 10.1 GFAP SMARCB1
8 choroid plexus cancer 10.1 GFAP SMARCB1
9 large cell carcinoma with rhabdoid phenotype 10.1 ENO2 SMARCB1
10 epithelioid malignant peripheral nerve sheath tumor 10.1 ENO2 SMARCB1
11 cerebellopontine angle tumor 10.1 GFAP SMARCB1
12 kidney rhabdoid cancer 10.1 ENO2 SMARCB1
13 rhabdoid cancer 10.1 ENO2 SMARCB1
14 extraosseous chondrosarcoma 10.1 ENO2 SMARCB1
15 intracranial cysts 10.1 ENO2 GFAP
16 primitive neuroectodermal tumor of the cervix uteri 10.1 ENO2 GFAP
17 large cell carcinoma 10.1 CEACAM5 ENO2
18 cerebellar medulloblastoma 10.0 ENO2 GFAP
19 central nervous system primitive neuroectodermal neoplasm 10.0 ENO2 GFAP
20 atypical follicular adenoma 10.0 CEACAM5 ENO2
21 clear cell ependymoma 10.0 ENO2 GFAP
22 ependymoma 10.0 ENO2 GFAP
23 plexiform schwannoma 10.0 ENO2 GFAP
24 cerebral neuroblastoma 10.0 ENO2 GFAP
25 subependymal glioma 10.0 ENO2 GFAP
26 atypical teratoid rhabdoid tumor 10.0 GFAP SMARCB1
27 astroblastoma 10.0 ENO2 GFAP
28 microcystic meningioma 10.0 ENO2 GFAP
29 pineal gland cancer 10.0 ENO2 GFAP
30 melanotic neuroectodermal tumor 10.0 ENO2 GFAP
31 benign ependymoma 10.0 ENO2 GFAP
32 pineocytoma 10.0 ENO2 GFAP
33 gastric small cell carcinoma 10.0 CEACAM5 ENO2
34 subependymoma 10.0 ENO2 GFAP
35 mucinous ovarian cystadenoma 10.0 CEACAM5 ENO2
36 benign glioma 10.0 ENO2 GFAP
37 breast adenomyoepithelioma 10.0 CEACAM5 ENO2
38 breast myoepithelial neoplasm 10.0 CEACAM5 ENO2
39 papillary ependymoma 10.0 ENO2 GFAP
40 central neurocytoma 10.0 ENO2 GFAP
41 granular cell tumor 10.0 ENO2 GFAP
42 cystic teratoma 10.0 ENO2 GFAP
43 subependymal giant cell astrocytoma 10.0 ENO2 GFAP
44 chondrosarcoma, extraskeletal myxoid 10.0 ENO2 SMARCB1
45 central nervous system benign neoplasm 10.0 ENO2 GFAP
46 traumatic brain injury 10.0 ENO2 GFAP
47 brain injury 10.0 ENO2 GFAP
48 congenital epulis 10.0 CEACAM5 ENO2
49 mixed ductal-endocrine carcinoma 10.0 CEACAM5 ENO2
50 juvenile pilocytic astrocytoma 10.0 ENO2 GFAP

Graphical network of the top 20 diseases related to Melanotic Medulloblastoma:



Diseases related to Melanotic Medulloblastoma

Symptoms & Phenotypes for Melanotic Medulloblastoma

UMLS symptoms related to Melanotic Medulloblastoma:


vomiting, gait ataxia, headache

Drugs & Therapeutics for Melanotic Medulloblastoma

Search Clinical Trials , NIH Clinical Center for Melanotic Medulloblastoma

Genetic Tests for Melanotic Medulloblastoma

Anatomical Context for Melanotic Medulloblastoma

MalaCards organs/tissues related to Melanotic Medulloblastoma:

41
Lung, Brain, Kidney, Liver, Ovary, Thyroid, Testis

Publications for Melanotic Medulloblastoma

Articles related to Melanotic Medulloblastoma:

# Title Authors Year
1
Melanotic medulloblastoma in children. ( 21267583 )
2011
2
Immunohistochemical and proteomic profile of melanotic medulloblastoma. ( 19061219 )
2009
3
Melanotic medulloblastoma of cerebellum: a case report. ( 16758682 )
2005
4
[An exceptional variety of medulloblastoma: melanotic medulloblastoma]. ( 9526628 )
1997
5
Melanotic medulloblastoma. A case report with immunohistochemical and ultrastructural examination. ( 3188844 )
1988
6
Melanotic medulloblastoma. Report of a case with ultrastructural findings. ( 690672 )
1978
7
Melanotic medulloblastoma of the cerebellum. ( 4353408 )
1973

Variations for Melanotic Medulloblastoma

Expression for Melanotic Medulloblastoma

Search GEO for disease gene expression data for Melanotic Medulloblastoma.

Pathways for Melanotic Medulloblastoma

Pathways related to Melanotic Medulloblastoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.66 EPPK1 GFAP

GO Terms for Melanotic Medulloblastoma

Cellular components related to Melanotic Medulloblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 8.62 EPPK1 GFAP

Biological processes related to Melanotic Medulloblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament organization GO:0045109 8.62 EPPK1 GFAP

Sources for Melanotic Medulloblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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