MCID: MLN001
MIFTS: 35

Melanotic Neuroectodermal Tumor

Categories: Bone diseases, Cancer diseases, Neuronal diseases, Oral diseases

Aliases & Classifications for Melanotic Neuroectodermal Tumor

MalaCards integrated aliases for Melanotic Neuroectodermal Tumor:

Name: Melanotic Neuroectodermal Tumor 12 15
Neuroectodermal Tumor, Melanotic 44 73
Infantile Melanotic Neuroectodermal Neoplasm 12
Pigmented Neuroectodermal Tumour of Infancy 12
Melanotic Neuroectodermal Tumor of Infancy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:166
MeSH 44 D017600
NCIt 50 C3717
SNOMED-CT 68 1513001
UMLS 73 C0206094

Summaries for Melanotic Neuroectodermal Tumor

MalaCards based summary : Melanotic Neuroectodermal Tumor, also known as neuroectodermal tumor, melanotic, is related to epulis and liver angiosarcoma. An important gene associated with Melanotic Neuroectodermal Tumor is ENO2 (Enolase 2), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include bone, brain and pineal.

Wikipedia : 76 Melanotic neuroectodermal tumor of infancy (MNTI) is a very rare oral cavity tumor that is seen in... more...

Related Diseases for Melanotic Neuroectodermal Tumor

Diseases related to Melanotic Neuroectodermal Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 225)
# Related Disease Score Top Affiliating Genes
1 epulis 30.4 ENO2 VIM
2 liver angiosarcoma 10.2 ENO2 VIM
3 congenital epulis 10.2 ENO2 VIM
4 chondrosarcoma, extraskeletal myxoid 10.2 ENO2 SYP
5 paraganglioma 10.2 ENO2 SYP
6 malignant pheochromocytoma 10.2 ENO2 SYP
7 peripheral nervous system neoplasm 10.2 ENO2 SYP
8 mixed cell type cancer 10.2 ENO2 SYP
9 adrenal rest tumor 10.2 ENO2 SYP
10 sweat gland cancer 10.2 ENO2 SYP
11 cranial nerve malignant neoplasm 10.2 ENO2 SYP
12 optic nerve neoplasm 10.2 ENO2 SYP
13 lung benign neoplasm 10.2 ENO2 SYP
14 olfactory neuroblastoma 10.2 ENO2 SYP
15 adrenal carcinoma 10.2 ENO2 SYP
16 large cell carcinoma 10.2 ENO2 SYP
17 pineal parenchymal tumor of intermediate differentiation 10.2 ENO2 SYP
18 horseshoe kidney 10.2 ENO2 SYP
19 bednar tumor 10.2 ENO2 VIM
20 leiomyosarcoma 10.2 ENO2 VIM
21 fibrolamellar carcinoma 10.2 SYP VIM
22 pilomatrixoma 10.2 ENO2 MUC1
23 brain injury 10.2 ENO2 GFAP
24 epithelioid leiomyosarcoma 10.2 ENO2 VIM
25 traumatic brain injury 10.2 ENO2 GFAP
26 ileum cancer 10.2 ENO2 GFAP
27 carotid body cancer 10.2 ENO2 SYP
28 duodenum cancer 10.2 ENO2 MUC1
29 status epilepticus 10.2 ENO2 GFAP
30 malignant sertoli cell tumor 10.2 ENO2 SYP
31 urinary bladder small cell neuroendocrine carcinoma 10.2 ENO2 SYP
32 dysgerminoma 10.2 ENO2 MUC1
33 small cell carcinoma 10.2 ENO2 SYP
34 scrapie 10.2 ENO2 GFAP
35 dysgerminoma of ovary 10.2 ENO2 GFAP
36 auditory system cancer 10.2 ENO2 SYP
37 juvenile pilocytic astrocytoma 10.2 ENO2 GFAP
38 gallbladder small cell carcinoma 10.2 ENO2 SYP
39 pancreatic somatostatinoma 10.2 ENO2 SYP
40 cutaneous ganglioneuroma 10.2 ENO2 SYP
41 extrahepatic bile duct adenocarcinoma 10.2 ENO2 SYP
42 small cell carcinoma of the bladder 10.2 ENO2 SYP
43 sensory organ benign neoplasm 10.2 ENO2 SYP
44 hemangiopericytoma, malignant 10.2 MUC1 VIM
45 orbital cancer 10.2 ENO2 SYP
46 sarcoma, synovial 10.2 MUC1 VIM
47 osteofibrous dysplasia 10.2 MUC1 VIM
48 angiosarcoma 10.2 MUC1 VIM
49 malignant fibroxanthoma 10.2 MUC1 VIM
50 myoepithelioma 10.2 GFAP VIM

Graphical network of the top 20 diseases related to Melanotic Neuroectodermal Tumor:



Diseases related to Melanotic Neuroectodermal Tumor

Symptoms & Phenotypes for Melanotic Neuroectodermal Tumor

Drugs & Therapeutics for Melanotic Neuroectodermal Tumor

Search Clinical Trials , NIH Clinical Center for Melanotic Neuroectodermal Tumor

Cochrane evidence based reviews: neuroectodermal tumor, melanotic

Genetic Tests for Melanotic Neuroectodermal Tumor

Anatomical Context for Melanotic Neuroectodermal Tumor

MalaCards organs/tissues related to Melanotic Neuroectodermal Tumor:

41
Bone, Brain, Pineal, Lung, Ovary, Cervix, Cerebellum

Publications for Melanotic Neuroectodermal Tumor

Articles related to Melanotic Neuroectodermal Tumor:

(show top 50) (show all 196)
# Title Authors Year
1
Clinical and immunohistochemical study of melanotic neuroectodermal tumor of infancy in the maxilla. ( 29768520 )
2018
2
Melanotic neuroectodermal tumor of infancy: A rare case report. ( 29491604 )
2018
3
Melanotic neuroectodermal tumor of infancy (MNTI) of the head and neck: A French multicenter study. ( 29275074 )
2018
4
Melanotic Neuroectodermal Tumor of Infancy in the Maxilla. ( 28968318 )
2018
5
Spontaneous Regression of Diffuse Periosteal Melanotic Neuroectodermal Tumor of Infancy in the Tibia, With 13-Year Follow-up. ( 29621061 )
2018
6
Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy. ( 30158782 )
2018
7
Melanotic neuroectodermal tumor of infancy: A rare pediatric head and neck lesion. ( 30178566 )
2018
8
Melanotic neuroectodermal tumor of infancy of the jaw bones: Update on the factors influencing survival and recurrence. ( 30390348 )
2018
9
Melanotic Neuroectodermal Tumor of Infancy: Case Report and Review of Management. ( 30392845 )
2018
10
Epididymal melanotic neuroectodermal tumor of infancy: A rare cause of scrotal mass in an infant. ( 30393869 )
2018
11
Melanotic Neuroectodermal Tumor of Infancy. ( 30407852 )
2018
12
Melanotic Neuroectodermal Tumor of Infancy: a Clinicopathological Case Report. ( 30462768 )
2018
13
Melanotic neuroectodermal tumor of infancy: a rare presentation of an extremely rare neoplasm and diagnostic implications in Gombe, Nigeria. ( 29138651 )
2017
14
Melanotic Neuroectodermal Tumor of Infancy of the Upper Arm: A Case Report. ( 29179213 )
2017
15
Giant melanotic neuroectodermal tumor of infancy (melanotic progonoma) of the head and neck: report of a malignant case. ( 28291424 )
2017
16
Prenatal Diagnosis of a Melanotic Neuroectodermal Tumor of Infancy (MNTI): A Case Report With a Favorable Outcome After Chemotherapy Failure and Incomplete Resection. ( 29016414 )
2017
17
Melanotic Neuroectodermal Tumor of Infancy Presenting With Fast-Growing Scrotal Swelling: A Case Report and Literature Review. ( 28812465 )
2017
18
Metastatic Melanotic Neuroectodermal Tumor of Infancy: Report of a Case and Review of the Literature. ( 27393580 )
2016
19
Mandibular melanotic neuroectodermal tumor of infancy: a role for neoadjuvant chemotherapy. ( 27107579 )
2016
20
A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report. ( 27519597 )
2016
21
Melanotic Neuroectodermal Tumor of Infancy in the Epididymis: A Brief Report and Review of the Role of Chemotherapy in Management. ( 26886373 )
2016
22
Obturator Prostheses for Melanotic Neuroectodermal Tumor of Infancy in the Maxilla. ( 26703043 )
2016
23
Melanotic Neuroectodermal Tumor of Infancy. ( 27504436 )
2016
24
Melanotic Neuroectodermal Tumor of Infancy with Involvement of the Superior Sagittal Sinus. ( 27595482 )
2016
25
Clinicopathological features of melanotic neuroectodermal tumor of infancy: Report of two cases. ( 26602435 )
2016
26
Protumorigenic M2-like phenotype cell infiltration in the melanotic neuroectodermal tumor of infancy. ( 26686956 )
2016
27
Melanotic neuroectodermal tumor of infancy: Cytology and histopathology of a rare lesion at an uncommon site. ( 28051837 )
2016
28
Melanotic neuroectodermal tumor of infancy. ( 27095686 )
2016
29
Melanotic Neuroectodermal Tumor of Infancy Presenting with Fast Growing Scrotal Swelling: A Case Report and Literature Review. ( 26669807 )
2015
30
Melanotic Neuroectodermal Tumor of Infancy: A Systematic Review. ( 25936939 )
2015
31
Extensive Melanotic Neuroectodermal Tumor of Infancy. ( 26581397 )
2015
32
Reconstruction of anterior maxillary defect with buccal pad fat after excision of melanotic neuroectodermal tumor of infancy. ( 26981478 )
2015
33
Melanotic neuroectodermal tumor of infancy in the soft tissue of the forearm: report of a case. ( 26722579 )
2015
34
Melanotic neuroectodermal tumor of infancy: review of literature, report of a case and follow up at 7 years. ( 25579681 )
2015
35
Melanotic neuroectodermal tumor of infancy: A case report and review of the surgical treatment. ( 25435930 )
2015
36
Melanotic neuroectodermal tumor of infancy in the skull: a case report. ( 26690602 )
2015
37
Prenatal Diagnosis Of Orbital Melanotic Neuroectodermal Tumor Of Infancy. ( 25594399 )
2015
38
Fine-needle aspiration cytology of melanotic neuroectodermal tumor of infancy. ( 26173836 )
2015
39
BRAFV600E Mutation in Melanotic Neuroectodermal Tumor of Infancy: Toward Personalized Medicine? ( 26122804 )
2015
40
Oral melanotic neuroectodermal tumor of infancy. ( 24531607 )
2014
41
Melanotic Neuroectodermal Tumor of Infancy: A Wolf in Sheep's Clothing. ( 25030945 )
2014
42
Melanotic neuroectodermal tumor of infancy disseminated by a ventriculoperitoneal shunt and diagnosed from the inguinal sac. ( 23823108 )
2014
43
Maxillary melanotic neuroectodermal tumor of infancy management: is conservative surgery the best approach? ( 23851860 )
2013
44
Melanotic Neuroectodermal Tumor of Infancy Arising in the Temporal Bone. ( 23965399 )
2013
45
Melanotic neuroectodermal tumor of infancy in an African-indigenous patient from the Amazon: a case report. ( 24274360 )
2013
46
Melanotic neuroectodermal tumor of infancy in the maxilla. ( 24083035 )
2013
47
Melanotic neuroectodermal tumor of infancy: A rare case report. ( 24403811 )
2013
48
Melanotic neuroectodermal tumor of infancy: A rare case report with differential diagnosis and review of the literature. ( 22557910 )
2012
49
Cigar-shaped melanin granules in melanotic neuroectodermal tumor of infancy. ( 21563320 )
2012
50
Melanotic neuroectodermal tumor of infancy. ( 22092370 )
2012

Variations for Melanotic Neuroectodermal Tumor

Expression for Melanotic Neuroectodermal Tumor

Search GEO for disease gene expression data for Melanotic Neuroectodermal Tumor.

Pathways for Melanotic Neuroectodermal Tumor

Pathways related to Melanotic Neuroectodermal Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.79 DBH ENO2 GFAP SYP
2 10.7 GFAP SYP VIM

GO Terms for Melanotic Neuroectodermal Tumor

Biological processes related to Melanotic Neuroectodermal Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron projection development GO:0010977 9.32 GFAP VIM
2 intermediate filament organization GO:0045109 9.26 GFAP VIM
3 astrocyte development GO:0014002 9.16 GFAP VIM
4 Bergmann glial cell differentiation GO:0060020 8.96 GFAP VIM
5 intermediate filament-based process GO:0045103 8.62 GFAP VIM

Sources for Melanotic Neuroectodermal Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....