MCID: MLN063
MIFTS: 25

Melon Allergy

Categories: Immune diseases

Aliases & Classifications for Melon Allergy

MalaCards integrated aliases for Melon Allergy:

Name: Melon Allergy 12 15
Cucumis Melo Fruit Allergy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060509

Summaries for Melon Allergy

Disease Ontology : 12 A fruit allergy triggered by Cucumis melo plant fruit food product.

MalaCards based summary : Melon Allergy, also known as cucumis melo fruit allergy, is related to fruit allergy and corticosteroid allergy. An important gene associated with Melon Allergy is PDCL (Phosducin Like), and among its related pathways/superpathways are Cardiac conduction and cGMP-PKG signaling pathway. Affiliated tissues include bone, heart and skin.

Related Diseases for Melon Allergy

Diseases related to Melon Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 162)
# Related Disease Score Top Affiliating Genes
1 fruit allergy 30.2 PDCL PDC
2 corticosteroid allergy 10.3 PDCL COPS7A
3 timothy grass allergy 10.3 PDCL PDC
4 wheat allergy 10.3 PDCL COPS7A
5 tomato allergy 10.2 PDCL PDC COPS7A
6 legume allergy 10.2 PDCL PDC COPS7A
7 apple allergy 10.2 PPIC PDCL PDC
8 respiratory allergy 10.2 PDCL PDC COPS7A
9 egg allergy 10.2 PDCL COPS7A
10 anisakiasis 10.2 TPM4 TPM2
11 epithelioid inflammatory myofibroblastic sarcoma 10.2 TPM4 TPM3
12 orange allergy 10.2 PVALB PDCL PDC
13 cap myopathy 10.2 TPM3 TPM2
14 ascaris lumbricoides infection 10.1 TPM4 TPM2 COPS7A
15 food allergy 10.1
16 peach allergy 10.1 PPIC PDCL PDC NACA2
17 congenital structural myopathy 10.0 TPM4 TPM3 TPM2
18 nose disease 10.0 PDCL PDC ALB
19 childhood-onset nemaline myopathy 10.0 TPM3 TPM2
20 myopathy, centronuclear, 2 10.0 TPM4 TPM3 TPM2
21 ostertagiasis 10.0 GAST ALB
22 congenital fiber-type disproportion 10.0 TPM4 TPM3 TPM2
23 arthrogryposis, distal, type 1a 10.0 TPM4 TPM3 TPM2
24 pollen allergy 10.0
25 urticaria 10.0
26 meckel diverticulum 9.9 ATP4A ALB
27 pthirus pubis infestation 9.9 TPM4 TPM2 TPM1 COPS7A
28 gastric fundus cancer 9.9 GAST ALB
29 vagus nerve disease 9.9 ATP4A ATP12A
30 necrotizing gastritis 9.9 ATP4A ATP12A
31 scalp dermatosis 9.9 ATP4A ATP12A
32 hemangioma of intra-abdominal structure 9.9 ATP4A ATP12A
33 acquired gastric outlet stenosis 9.9 ATP4A ATP12A
34 lingual goiter 9.9 ATP4A ATP12A
35 bacterial esophagitis 9.9 ATP4A ATP12A
36 cascade stomach 9.9 ATP4A ATP12A
37 benzylpenicillin allergy 9.9 ATP4A ATP12A
38 median arcuate ligament syndrome 9.9 ATP4A ATP12A
39 nasal cavity disease 9.9 PDCL PDC COPS7A ALB
40 cervix erosion 9.9 ATP4A ATP12A
41 angiodysplasia of intestine 9.9 ATP4A ATP12A
42 angiodysplasia 9.9 ATP4A ATP12A
43 laryngeal tuberculosis 9.9 ATP4A ATP12A
44 fungal esophagitis 9.9 ATP4A ATP12A
45 dieulafoy lesion 9.9 ATP4A ATP12A
46 esophagus melanoma 9.9 ATP4A ATP12A
47 cefuroxime allergy 9.9 ATP4A ATP12A
48 emphysematous cholecystitis 9.9 ATP4A ATP12A
49 superior mesenteric artery syndrome 9.9 ATP4A ATP12A
50 pneumatosis cystoides intestinalis 9.9 ATP4A ATP12A

Graphical network of the top 20 diseases related to Melon Allergy:



Diseases related to Melon Allergy

Symptoms & Phenotypes for Melon Allergy

Drugs & Therapeutics for Melon Allergy

Search Clinical Trials , NIH Clinical Center for Melon Allergy

Genetic Tests for Melon Allergy

Anatomical Context for Melon Allergy

MalaCards organs/tissues related to Melon Allergy:

40
Bone, Heart, Skin, Cervix

Publications for Melon Allergy

Articles related to Melon Allergy:

(show all 13)
# Title Authors PMID Year
1
Type IV chitinase quantification in four different grape cultivars (Vitis vinifera) in northeast of Iran by an indirect sandwich enzyme-linked immunosorbent assay. 61
30346872 2019
2
Molecular characterization of contact urticaria in patients with melon allergy. 61
24640940 2014
3
Molecular cloning, characterization, and expression of Cuc m 2, a major allergen in Cucumis melo. 61
26989709 2013
4
Validity of using recombinant melon profilin, Cuc m 2, for diagnosis of melon allergy. 61
26989703 2012
5
The nature of melon allergy in ragweed-allergic subjects: A study of 1000 patients. 61
21262100 2011
6
An experimental and modeling-based approach to locate IgE epitopes of plant profilin allergens. 61
17397911 2007
7
Sequence homology: a poor predictive value for profilins cross-reactivity. 61
16153305 2005
8
Allergenic reactivity of the melon profilin Cuc m 2 and its identification as major allergen. 61
16120089 2005
9
Clinical characteristics of melon (Cucumis melo) allergy. 61
14533664 2003
10
Profilin is a relevant melon allergen susceptible to pepsin digestion in patients with oral allergy syndrome. 61
12642849 2003
11
Randomized, double-blind, crossover challenge study in 53 subjects reporting adverse reactions to melon (Cucumis melo). 61
11080722 2000
12
Fennel, cucumber, and melon allergy successfully treated with pollen-specific injection immunotherapy. 61
10795656 2000
13
[Prince Melon allergy (author's transl)]. 61
7115088 1982

Variations for Melon Allergy

Expression for Melon Allergy

Search GEO for disease gene expression data for Melon Allergy.

Pathways for Melon Allergy

GO Terms for Melon Allergy

Cellular components related to Melon Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 10.06 TPM4 TPM3 TPM2 TPM1 PVALB PPIC
2 actin cytoskeleton GO:0015629 9.56 TPM4 TPM3 TPM2 TPM1
3 stress fiber GO:0001725 9.33 TPM4 TPM3 TPM1
4 actin filament GO:0005884 9.26 TPM4 TPM3 TPM2 TPM1
5 muscle thin filament tropomyosin GO:0005862 8.92 TPM4 TPM3 TPM2 TPM1

Biological processes related to Melon Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin filament organization GO:0007015 9.46 TPM4 TPM3 TPM2 TPM1
2 cellular sodium ion homeostasis GO:0006883 9.4 ATP4A ATP12A
3 sodium ion export across plasma membrane GO:0036376 9.37 ATP4A ATP12A
4 cellular potassium ion homeostasis GO:0030007 9.32 ATP4A ATP12A
5 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.26 ATP4A ATP12A
6 muscle contraction GO:0006936 9.26 TPM4 TPM3 TPM2 TPM1
7 muscle filament sliding GO:0030049 8.92 TPM4 TPM3 TPM2 TPM1

Molecular functions related to Melon Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin binding GO:0003779 9.67 TPM4 TPM3 TPM2 TPM1
2 actin filament binding GO:0051015 9.46 TPM4 TPM3 TPM2 TPM1
3 sodium:potassium-exchanging ATPase activity GO:0005391 9.32 ATP4A ATP12A
4 potassium-transporting ATPase activity GO:0008556 9.26 ATP4A ATP12A
5 structural constituent of muscle GO:0008307 9.13 TPM4 TPM2 TPM1
6 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Melon Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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