MCID: MNN010
MIFTS: 26

Meningeal Melanoma

Categories: Cancer diseases, Neuronal diseases, Skin diseases

Aliases & Classifications for Meningeal Melanoma

MalaCards integrated aliases for Meningeal Melanoma:

Name: Meningeal Melanoma 12 15
Melanoma of the Leptomeninges 12
Leptomeningeal Melanoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:6085
NCIt 50 C5317
UMLS 73 C1334386

Summaries for Meningeal Melanoma

MalaCards based summary : Meningeal Melanoma, also known as melanoma of the leptomeninges, is related to melanoma and primary melanoma of the central nervous system, and has symptoms including vomiting, headache and neurologic symptoms. An important gene associated with Meningeal Melanoma is MITF (Melanocyte Inducing Transcription Factor), and among its related pathways/superpathways are Pathways in cancer and Glioma. Affiliated tissues include skin and spinal cord, and related phenotype is pigmentation.

Related Diseases for Meningeal Melanoma

Diseases related to Meningeal Melanoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 melanoma 30.2 CDKN2A MITF
2 primary melanoma of the central nervous system 11.2
3 malignant leptomeningeal tumor 9.8 CDKN2A MITF
4 neurofibroma 9.8 CDKN2A MITF
5 skin melanoma 9.8 CDKN2A MITF
6 melanoma, uveal 9.8 CDKN2A MITF
7 neurofibromatosis, type iv, of riccardi 9.7
8 melanosis, neurocutaneous 9.7
9 chronic meningitis 9.7
10 lactic acidosis 9.7
11 meningitis 9.7
12 nevus of ota 9.7
13 melanoma, cutaneous malignant 1 9.7 CDKN2A MITF

Graphical network of the top 20 diseases related to Meningeal Melanoma:



Diseases related to Meningeal Melanoma

Symptoms & Phenotypes for Meningeal Melanoma

UMLS symptoms related to Meningeal Melanoma:


vomiting, headache, neurologic symptoms

MGI Mouse Phenotypes related to Meningeal Melanoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 pigmentation MP:0001186 8.62 CDKN2A MITF

Drugs & Therapeutics for Meningeal Melanoma

Search Clinical Trials , NIH Clinical Center for Meningeal Melanoma

Genetic Tests for Meningeal Melanoma

Anatomical Context for Meningeal Melanoma

MalaCards organs/tissues related to Meningeal Melanoma:

41
Skin, Spinal Cord

Publications for Meningeal Melanoma

Articles related to Meningeal Melanoma:

(show all 23)
# Title Authors Year
1
Primary intracranial meningeal melanoma mimicking chronic meningitis: A case report. ( 30497968 )
2018
2
Amelanotic Meningeal Melanoma with Leptomeningeal Dissemination: A Case Report and Systematic Literature Review. ( 30404049 )
2018
3
Primary meningeal melanoma with cerebrospinal fluid dissemination mimicking neurofibromatosis type 2. ( 26200063 )
2015
4
Central lactic acidosis, hyperventilation, and respiratory alkalosis: leading clinical features in a 3-year-old boy with malignant meningeal melanoma. ( 17534659 )
2008
5
Large primary meningeal melanoma in an adult patient with neurocutaneous melanosis. ( 17382464 )
2007
6
Malignant meningeal melanoma. ( 10935858 )
1998
7
Meningeal melanoma associated with nevus of Ota: case report and review. ( 8324963 )
1993
8
Primary meningeal melanoma. ( 2706127 )
1989
9
Primary meningeal melanoma. ( 3394553 )
1988
10
Computed tomography of primary melanoma of the leptomeninges: case reports. ( 4053661 )
1985
11
Primary melanoma of the leptomeninges. A report of two cases. ( 7173972 )
1982
12
Primary melanoma of the leptomeninges. ( 4455630 )
1974
13
Primary melanoma of the leptomeninges: a review. ( 4610369 )
1974
14
Primary melanoma of the leptomeninges. ( 4642971 )
1972
15
Primary malignant melanoma of the leptomeninges associated with hypoglycorrhachia. ( 5566104 )
1971
16
Primary melanoma of the leptomeninges of the spinal cord. A case report and review of the literature. ( 5269783 )
1970
17
Primary melanoma of the leptomeninges. ( 5459290 )
1970
18
Primary malignant meningeal melanoma associated with benign hairy naevi. ( 5361285 )
1969
19
Spinal (meningeal) melanoma. A case report. ( 5658558 )
1968
20
Malignant meningeal melanoma in a 3-year-old boy. A case report. ( 5964542 )
1966
21
Histological studies on malignant melanoma. Characteristics of primary malignant melanoma of the leptomeninges. ( 13960179 )
1963
22
Primary melanoma of the leptomeninges. ( 13513785 )
1958
23
Primary melanoma of the leptomeninges. ( 15390905 )
1949

Variations for Meningeal Melanoma

Expression for Meningeal Melanoma

Search GEO for disease gene expression data for Meningeal Melanoma.

Pathways for Meningeal Melanoma

GO Terms for Meningeal Melanoma

Biological processes related to Meningeal Melanoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 8.96 CDKN2A MITF
2 positive regulation of gene expression GO:0010628 8.62 CDKN2A MITF

Sources for Meningeal Melanoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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