MCID: MNN006
MIFTS: 31

Meninges Hemangiopericytoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Meninges Hemangiopericytoma

MalaCards integrated aliases for Meninges Hemangiopericytoma:

Name: Meninges Hemangiopericytoma 12 15
Hemangiopericytoma of Meninges 12 73
Meningeal Hemangiopericytoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4957
NCIt 50 C4660
UMLS 73 C0349622

Summaries for Meninges Hemangiopericytoma

MalaCards based summary : Meninges Hemangiopericytoma, also known as hemangiopericytoma of meninges, is related to hemangiopericytoma, malignant and mesenchymal chondrosarcoma. An important gene associated with Meninges Hemangiopericytoma is STAT6 (Signal Transducer And Activator Of Transcription 6), and among its related pathways/superpathways are Pathways in cancer and Immune response Function of MEF2 in T lymphocytes. Affiliated tissues include brain, liver and bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Meninges Hemangiopericytoma

Diseases related to Meninges Hemangiopericytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 hemangiopericytoma, malignant 30.4 IGF2 STAT6 VIM
2 mesenchymal chondrosarcoma 29.3 HEY1 NCOA2 VIM
3 hypoglycemia 10.3
4 chondrosarcoma 9.9
5 obstructive jaundice 9.9
6 fibrous meningioma 9.9
7 meningothelial meningioma 9.9
8 periosteal chondrosarcoma 9.9 HEY1 NCOA2
9 meningioma, familial 9.9 IGF2 STAT6
10 rhabdoid tumor predisposition syndrome 1 9.8 IGF2 VIM
11 leiomyosarcoma 9.8 IGF2 VIM
12 leiomyoma 9.8 IGF2 VIM
13 gastrointestinal stromal tumor 9.7 IGF2 VIM

Graphical network of the top 20 diseases related to Meninges Hemangiopericytoma:



Diseases related to Meninges Hemangiopericytoma

Symptoms & Phenotypes for Meninges Hemangiopericytoma

GenomeRNAi Phenotypes related to Meninges Hemangiopericytoma according to GeneCards Suite gene sharing:

26 (show all 22)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.6 NCOA2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.6 VIM
3 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.6 VIM
4 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.6 VIM
5 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.6 STAT6 VIM
6 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.6 NCOA2 STAT6 VIM
7 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.6 VIM
8 Increased shRNA abundance (Z-score > 2) GR00366-A-201 9.6 STAT6
9 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.6 VIM
10 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.6 VIM
11 Increased shRNA abundance (Z-score > 2) GR00366-A-39 9.6 STAT6
12 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.6 STAT6
13 Increased shRNA abundance (Z-score > 2) GR00366-A-54 9.6 STAT6
14 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.6 VIM
15 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.6 STAT6
16 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.6 VIM
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-134 9.5 VIM
18 Decreased shRNA abundance (Z-score < -2) GR00366-A-150 9.5 NCOA2
19 Decreased shRNA abundance (Z-score < -2) GR00366-A-212 9.5 NCOA2 VIM
20 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.5 NCOA2
21 Decreased shRNA abundance (Z-score < -2) GR00366-A-59 9.5 NCOA2
22 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.5 VIM

MGI Mouse Phenotypes related to Meninges Hemangiopericytoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.55 HEY1 IGF2 NCOA2 STAT6 VIM
2 embryo MP:0005380 9.26 HEY1 IGF2 NCOA2 VIM
3 reproductive system MP:0005389 8.92 IGF2 NCOA2 STAT6 VIM

Drugs & Therapeutics for Meninges Hemangiopericytoma

Search Clinical Trials , NIH Clinical Center for Meninges Hemangiopericytoma

Genetic Tests for Meninges Hemangiopericytoma

Anatomical Context for Meninges Hemangiopericytoma

MalaCards organs/tissues related to Meninges Hemangiopericytoma:

41
Brain, Liver, Bone, T Cells

Publications for Meninges Hemangiopericytoma

Articles related to Meninges Hemangiopericytoma:

# Title Authors Year
1
Hemangiopericytoma of meninges--a "malignant" challenge. ( 24631649 )
2015
2
Hemangiopericytoma of meninges. I. Histopathological variability and differential diagnosis. ( 3811681 )
1986
3
Hemangiopericytoma of meninges. II. General and clinical data. ( 3811682 )
1986

Variations for Meninges Hemangiopericytoma

Expression for Meninges Hemangiopericytoma

Search GEO for disease gene expression data for Meninges Hemangiopericytoma.

Pathways for Meninges Hemangiopericytoma

Pathways related to Meninges Hemangiopericytoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.52 HEY1 IGF2 STAT6
2
Show member pathways
11.41 IGF2 NCOA2
3 11.28 NCOA2 STAT6
4 11.01 STAT6 VIM

GO Terms for Meninges Hemangiopericytoma

Biological processes related to Meninges Hemangiopericytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.46 HEY1 IGF2 NCOA2 STAT6
2 positive regulation of transcription by RNA polymerase II GO:0045944 9.26 HEY1 IGF2 NCOA2 STAT6
3 negative regulation of transcription by RNA polymerase II GO:0000122 8.92 HEY1 IGF2 NCOA2 STAT6

Sources for Meninges Hemangiopericytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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