Meninges Sarcoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Meninges Sarcoma

MalaCards integrated aliases for Meninges Sarcoma:

Name: Meninges Sarcoma ¹² ¹⁵

Leptomeningeal Sarcoma ⁷³

Meningothelial Sarcoma ⁷³

Sarcoma of Meninges ¹²

Meningeal Sarcoma ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7614

NCIt ⁵⁰ C4073

SNOMED-CT ⁶⁸ 78303004

UMLS ⁷³ C0302327 C1384416

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Summaries for Meninges Sarcoma

MalaCards based summary : Meninges Sarcoma, also known as leptomeningeal sarcoma, is related to spindle cell rhabdomyosarcoma and frontal convexity meningioma. An important gene associated with Meninges Sarcoma is CSF1R (Colony Stimulating Factor 1 Receptor), and among its related pathways/superpathways are PI3K-Akt signaling pathway and MAPK Signaling: Mitogen Stimulation Pathway. Affiliated tissues include skin, brain and liver.

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Related Diseases for Meninges Sarcoma

Diseases related to Meninges Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 102)

#	Related Disease	Score	Top Affiliating Genes
1	spindle cell rhabdomyosarcoma	10.2	GFAP MB
2	frontal convexity meningioma	10.2	GFAP TP53
3	gliofibroma	10.2	GFAP TP53
4	cerebral convexity meningioma	10.2	GFAP TP53
5	cellular ependymoma	10.2	GFAP TP53
6	protoplasmic astrocytoma	10.2	GFAP TP53
7	central nervous system primitive neuroectodermal neoplasm	10.2	GFAP TP53
8	rhabdoid cancer	10.2	MB TP53
9	mixed glioma	10.2	GFAP TP53
10	spinal cancer	10.2	GFAP TP53
11	ependymoblastoma	10.2	GFAP TP53
12	cerebral ventricle cancer	10.2	GFAP TP53
13	adenosarcoma	10.2	MB TP53
14	chordoid glioma	10.2	GFAP TP53
15	pigmented villonodular synovitis	10.2	CSF1R TP53
16	pleuropulmonary blastoma	10.2	MB TP53
17	glioma susceptibility 1	10.2	GFAP TP53
18	dedifferentiated liposarcoma	10.2	MB TP53
19	malignant ependymoma	10.2	GFAP TP53
20	fibrillary astrocytoma	10.2	GFAP TP53
21	benign glioma	10.2	GFAP TP53
22	pleomorphic xanthoastrocytoma	10.2	GFAP TP53
23	spinal cord astrocytoma	10.2	GFAP TP53
24	myxosarcoma	10.2	MB TP53
25	gliomatosis cerebri	10.2	GFAP TP53
26	choroid plexus cancer	10.1	GFAP TP53
27	necrotizing sialometaplasia	10.1	GFAP TP53
28	mixed cell type cancer	10.1	MB TP53
29	deep leiomyoma	10.1	CD34 GFAP
30	cystic teratoma	10.1	GFAP TP53
31	adult fibrosarcoma	10.1	CD34 MB
32	plexiform schwannoma	10.1	CD34 GFAP
33	angiomyoma	10.1	CD34 MB
34	central nervous system benign neoplasm	10.1	GFAP TP53
35	cerebellar liponeurocytoma	10.1	GFAP TP53
36	atypical neurofibroma	10.1	CD34 GFAP
37	cellular neurofibroma	10.1	CD34 TP53
38	fibroepithelial basal cell carcinoma	10.1	CD34 TP53
39	juvenile pilocytic astrocytoma	10.1	GFAP TP53
40	adult medulloblastoma	10.1	GFAP TP53
41	malignant mesenchymoma	10.1	MB TP53
42	sarcomatoid squamous cell skin carcinoma	10.1	CD34 MB
43	cardiovascular organ benign neoplasm	10.1	CD34 MB
44	brain glioma	10.1	GFAP TP53
45	benign perivascular tumor	10.1	CD34 MB
46	sarcomatosis of the meninges	10.1	CTNNBL1 GFAP
47	breast benign neoplasm	10.1	CD34 TP53
48	thoracic benign neoplasm	10.1	CD34 TP53
49	spindle cell synovial sarcoma	10.1	CD34 MB
50	optic nerve glioma	10.1	GFAP TP53

Graphical network of the top 20 diseases related to Meninges Sarcoma:

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Symptoms & Phenotypes for Meninges Sarcoma

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Drugs & Therapeutics for Meninges Sarcoma

Search Clinical Trials , NIH Clinical Center for Meninges Sarcoma

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Genetic Tests for Meninges Sarcoma

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Anatomical Context for Meninges Sarcoma

MalaCards organs/tissues related to Meninges Sarcoma:

⁴¹

Skin, Brain, Liver, Spinal Cord, Skeletal Muscle, Myeloid, Small Intestine

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Publications for Meninges Sarcoma

Articles related to Meninges Sarcoma:

#	Title	Authors	Year
1	Primary diffuse leptomeningeal sarcoma with rhabdomyoblastic differentiation. A case report and immunohistochemical study. ( 15178217 )	de Oliveira MJ...Morais Dda C	2004

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Genes for Meninges Sarcoma

Genes related to Meninges Sarcoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CSF1R	Colony Stimulating Factor 1 Receptor	Protein Coding	14.36	DISEASES inferred ¹⁵
2	MB	Myoglobin	Protein Coding	14.22	DISEASES inferred ¹⁵
3	GFAP	Glial Fibrillary Acidic Protein	Protein Coding	13.98	DISEASES inferred ¹⁵
4	TP53	Tumor Protein P53	Protein Coding	13.76	DISEASES inferred ¹⁵
5	IGF2	Insulin Like Growth Factor 2	Protein Coding	13.68	DISEASES inferred ¹⁵
6	CREB3L2	CAMP Responsive Element Binding Protein 3 Like 2	Protein Coding	5.21	DISEASES inferred ¹⁵
7	CTNNBL1	Catenin Beta Like 1	Protein Coding	3.62	DISEASES inferred ¹⁵
8	GCG	Glucagon	Protein Coding	3.09	DISEASES inferred ¹⁵
9	CD34	CD34 Molecule	Protein Coding	3.03	DISEASES inferred ¹⁵

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Variations for Meninges Sarcoma

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Expression for Meninges Sarcoma

Search GEO for disease gene expression data for Meninges Sarcoma.

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Pathways for Meninges Sarcoma

Pathways related to Meninges Sarcoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	PI3K-Akt signaling pathway ³⁷ Show member pathways Human papillomavirus infection ³⁷	12.1	CREB3L2 CSF1R IGF2 TP53
2	MAPK Signaling: Mitogen Stimulation Pathway ⁶⁵ Show member pathways Akt Signaling Pathway ⁶⁵	11.52	CREB3L2 CSF1R TP53
3	AKT Signaling Pathway ⁶⁷	10.95	CREB3L2 CSF1R TP53

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GO Terms for Meninges Sarcoma

Biological processes related to Meninges Sarcoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of protein serine/threonine kinase activity	GO:0071902	8.96	CSF1R IGF2
2	cell proliferation	GO:0008283	8.92	CD34 CSF1R GCG TP53

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Sources for Meninges Sarcoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

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⁹ Cosmic

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¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

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³⁰ HGMD

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³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

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⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

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⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

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⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia