MCID: MNN011
MIFTS: 26

Meninges Sarcoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Meninges Sarcoma

MalaCards integrated aliases for Meninges Sarcoma:

Name: Meninges Sarcoma 12 15
Leptomeningeal Sarcoma 73
Meningothelial Sarcoma 73
Sarcoma of Meninges 12
Meningeal Sarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7614
NCIt 50 C4073
SNOMED-CT 68 277996009 78303004
UMLS 73 C0302327

Summaries for Meninges Sarcoma

MalaCards based summary : Meninges Sarcoma, also known as leptomeningeal sarcoma, is related to pigmented villonodular synovitis and adenosarcoma. An important gene associated with Meninges Sarcoma is CSF1R (Colony Stimulating Factor 1 Receptor), and among its related pathways/superpathways are MAPK signaling pathway and PI3K-Akt signaling pathway. Related phenotypes are craniofacial and limbs/digits/tail

Related Diseases for Meninges Sarcoma

Diseases related to Meninges Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 pigmented villonodular synovitis 10.4 CSF1R TP53
2 adenosarcoma 10.4 MB TP53
3 pleuropulmonary blastoma 10.4 MB TP53
4 mixed cell type cancer 10.4 MB TP53
5 myxosarcoma 10.4 MB TP53
6 medullomyoblastoma 10.3 MB TP53
7 malignant mesenchymoma 10.3 MB TP53
8 cerebral neuroblastoma 10.3 IGF2 TP53
9 papilloma of choroid plexus 10.3 IGF2 TP53
10 embryonal rhabdomyosarcoma 10.2 IGF2 MB
11 skeletal muscle cancer 10.2 IGF2 MB
12 histiocytoma 10.2 MB TP53
13 atypical teratoid rhabdoid tumor 10.1 IGF2 TP53
14 endocrine pancreas disease 10.1 GCG IGF2
15 pancreas disease 10.1 GCG IGF2
16 angiomyoma 10.0 CD34 MB
17 cellular neurofibroma 10.0 CD34 TP53
18 intestinal disease 10.0 GCG TP53
19 spindle cell synovial sarcoma 9.9 CD34 MB
20 breast benign neoplasm 9.9 CD34 TP53
21 cardiovascular organ benign neoplasm 9.9 CD34 MB
22 thoracic benign neoplasm 9.9 CD34 TP53
23 benign perivascular tumor 9.9 CD34 MB
24 liver angiosarcoma 9.9 CD34 TP53
25 gastric leiomyosarcoma 9.9 CD34 IGF2
26 glomangioma 9.9 CD34 MB
27 gastroesophageal reflux 9.9 GCG TP53
28 sarcoma 9.9
29 meningitis 9.9
30 clear cell ependymoma 9.8 CD34 TP53
31 leiomyosarcoma 9.8 IGF2 MB TP53
32 cellular schwannoma 9.8 CD34 TP53
33 rhabdomyosarcoma 9.8 IGF2 MB TP53
34 organ system benign neoplasm 9.8 CD34 TP53
35 endocrine gland cancer 9.8 GCG TP53
36 gliosarcoma 9.8
37 deep angioma 9.8 CD34 CREB3L2
38 conventional fibrosarcoma 9.8 CD34 CREB3L2
39 intramuscular hemangioma 9.7 CD34 CREB3L2
40 synovium cancer 9.7 CD34 CREB3L2
41 spindle cell liposarcoma 9.7 CD34 CREB3L2
42 peripheral nervous system neoplasm 9.7 CD34 TP53
43 infiltrating lipoma 9.7 CD34 CREB3L2
44 pleomorphic lipoma 9.7 CD34 CREB3L2
45 cell type benign neoplasm 9.7 CD34 TP53
46 skin sarcoma 9.7 CD34 CREB3L2
47 dermatofibrosarcoma protuberans 9.6 CD34 TP53
48 nervous system cancer 9.6 CD34 TP53
49 endometrial stromal sarcoma 9.6 MB TP53
50 sarcomatoid squamous cell skin carcinoma 9.5 CD34 MB TP53

Graphical network of the top 20 diseases related to Meninges Sarcoma:



Diseases related to Meninges Sarcoma

Symptoms & Phenotypes for Meninges Sarcoma

MGI Mouse Phenotypes related to Meninges Sarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.26 CREB3L2 CSF1R IGF2 TP53
2 limbs/digits/tail MP:0005371 8.92 CREB3L2 CSF1R IGF2 TP53

Drugs & Therapeutics for Meninges Sarcoma

Search Clinical Trials , NIH Clinical Center for Meninges Sarcoma

Genetic Tests for Meninges Sarcoma

Anatomical Context for Meninges Sarcoma

Publications for Meninges Sarcoma

Articles related to Meninges Sarcoma:

# Title Authors Year
1
Long-term survival in gliosarcoma with radiation-induced meningeal sarcomas: Case report and molecular features. ( 26458625 )
2015
2
Primary C1-2, intradural, extramedullary meningeal sarcoma with glial fibrillary acidic protein-immunoreactive components: a spinal gliosarcoma? Case report and review of the literature. ( 12450287 )
2002
3
Meningeal sarcoma with rhabdomyoblastic differentiation: case report. ( 1584397 )
1992

Variations for Meninges Sarcoma

Expression for Meninges Sarcoma

Search GEO for disease gene expression data for Meninges Sarcoma.

Pathways for Meninges Sarcoma

Pathways related to Meninges Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.17 CSF1R IGF2 TP53
2
Show member pathways
11.75 CREB3L2 CSF1R IGF2 TP53
3 11.29 CREB3L2 CSF1R TP53
4 11.15 CD34 CSF1R
5 11.02 CD34 CSF1R

GO Terms for Meninges Sarcoma

Biological processes related to Meninges Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 multicellular organism development GO:0007275 9.56 CREB3L2 CSF1R IGF2 TP53
2 hemopoiesis GO:0030097 9.32 CD34 CSF1R
3 negative regulation of apoptotic process GO:0043066 9.26 CSF1R GCG IGF2 TP53
4 positive regulation of protein serine/threonine kinase activity GO:0071902 9.16 CSF1R IGF2
5 cell proliferation GO:0008283 8.92 CD34 CSF1R GCG TP53

Molecular functions related to Meninges Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein phosphatase binding GO:0019903 8.62 CSF1R TP53

Sources for Meninges Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....