Meningoencephalitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: MNN009 MIFTS: 49	Meningoencephalitis Categories: Neuronal diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Meningoencephalitis

MalaCards integrated aliases for Meningoencephalitis:

Name: Meningoencephalitis ¹² ⁵⁵ ⁴⁴ ¹⁵ ⁷³

Classifications:

MalaCards categories:
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the nervous system

Inflammatory diseases of the central nervous system

Encephalitis, myelitis and encephalomyelitis

External Ids:

Disease Ontology ¹² DOID:10554

ICD10 ³³ A69.22 G04

MeSH ⁴⁴ D008590

NCIt ⁵⁰ C34813

SNOMED-CT ⁶⁸ 7125002

UMLS ⁷³ C0025309

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Summaries for Meningoencephalitis

Disease Ontology : ¹² A central nervous system disease that involves encephalitis which occurs along with meningitis.

MalaCards based summary : Meningoencephalitis is related to meningitis and acquired immunodeficiency syndrome. An important gene associated with Meningoencephalitis is CARD9 (Caspase Recruitment Domain Family Member 9), and among its related pathways/superpathways are Tuberculosis and C-type lectin receptor signaling pathway. The drugs Fluconazole and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include brain, pituitary and t cells, and related phenotypes are cellular and homeostasis/metabolism

Wikipedia : ⁷⁶ Meningoencephalitis (/mɪ�?nɪ�?ɡo�?�?n�?s�?f�?�?laɪtɪs, -�?nɪnd�?o�?-, -�?n-, -�?k�?-/; from Greek... more...

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Related Diseases for Meningoencephalitis

Diseases related to Meningoencephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 354)

#	Related Disease	Score	Top Affiliating Genes
1	meningitis	30.6	ALB IL6 TLR9
2	acquired immunodeficiency syndrome	30.3	ALB B2M IL6
3	parotitis	30.2	ALB CD79A
4	otitis media	30.0	ALB CD79A IL6
5	peritonitis	29.9	ALB B2M IL6
6	human immunodeficiency virus infectious disease	29.7	B2M CCL5 IL6 TLR9
7	toxoplasmosis	29.7	CD40LG CD79A IL6 TLR9
8	viral infectious disease	29.7	CCL5 CD40LG IL6 TLR9
9	syphilis	29.7	B2M CD40LG CD79A
10	pneumonia	29.6	CCL5 CD40LG IL6 TLR9
11	guillain-barre syndrome	29.6	ALB CD79A MBP
12	endometritis	29.5	CHKB IL6 SLC17A5
13	common variable immunodeficiency	29.3	CD40LG CD79A IL6 TLR9
14	systemic lupus erythematosus	29.3	ALB CCL5 CD40LG CD79A IL6 MECP2
15	multiple sclerosis	29.2	CCL5 IL6 MBP TLR9
16	yellow fever	29.2	CCL5 IL6 TLR9
17	inflammatory bowel disease	28.8	ALB CCL5 IL6 TAC1 TLR9
18	asthma	28.7	CCL5 CD40LG IL6 TAC1 TLR9
19	primary amebic meningoencephalitis	12.6
20	lymphocytic choriomeningitis	11.9
21	tick-borne encephalitis	11.3
22	trichinosis	11.3
23	pulmonary alveolar microlithiasis	11.0
24	parenchymatous neurosyphilis	11.0
25	tick infestation	11.0
26	amoebiasis due to free-living amoebae	11.0
27	listeriosis	10.6
28	west nile virus	10.3
29	tinea profunda	10.3	ALB CARD9
30	c1q nephropathy	10.3	CD40LG CD79A
31	immunoglobulin g deficiency	10.3	CD40LG CD79A
32	cryofibrinogenemia	10.3	CD40LG CD79A
33	fournier gangrene	10.3	ALB CD40LG
34	immunodeficiency 43	10.3	ALB B2M
35	heparin-induced thrombocytopenia	10.3	CD40LG CD79A
36	root caries	10.2	ALB CD79A
37	immunoglobulin a deficiency 1	10.2	CD40LG CD79A
38	sporotrichosis	10.2	CD40LG CD79A
39	congenital syphilis	10.2	CD40LG CD79A
40	extramedullary plasmacytoma	10.2	B2M IL6
41	mumps	10.2
42	secondary syphilis	10.2	CD40LG CD79A
43	orthostatic proteinuria	10.2	ALB B2M
44	diffuse glomerulonephritis	10.2	ALB B2M
45	herpes simplex	10.2
46	meningovascular neurosyphilis	10.2	ALB MBP
47	hemorrhagic fever with renal syndrome	10.2	ALB B2M IL6
48	plasma cell neoplasm	10.2	B2M CD79A IL6
49	vasomotor rhinitis	10.2	CD40LG TAC1
50	hydrocephalus	10.2

Graphical network of the top 20 diseases related to Meningoencephalitis:

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Symptoms & Phenotypes for Meningoencephalitis

MGI Mouse Phenotypes related to Meningoencephalitis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cellular	MP:0005384	10.11	ALB APP B2M CD40LG CD79A CREBBP
2	homeostasis/metabolism	MP:0005376	10.1	ALB APP B2M CARD9 CD40LG CD79A
3	behavior/neurological	MP:0005386	10.06	APP CHKB CREBBP IL6 MBP MECP2
4	hematopoietic system	MP:0005397	10.02	APP B2M CARD9 CCL5 CD40LG CD79A
5	immune system	MP:0005387	9.9	APP B2M CARD9 CCL5 CD40LG CD79A
6	integument	MP:0010771	9.5	APP B2M CD40LG CREBBP IL6 MECP2
7	nervous system	MP:0003631	9.32	APP B2M CD40LG CD79A CHKB CREBBP

Sources

Drugs & Therapeutics for Meningoencephalitis

Drugs for Meningoencephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 62)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Fluconazole

Approved, Investigational

Phase 3,Phase 2,Not Applicable

86386-73-4

3365

Miconazole

Approved, Investigational, Vet_approved

Phase 3,Phase 2,Not Applicable

22916-47-8

4189

Sertraline

Approved

Phase 3

79617-96-2

68617

Immunoglobulins

Phase 3,Phase 1,Phase 2

Antibodies

Phase 3,Phase 1,Phase 2

Immunologic Factors

Phase 3,Phase 2,Phase 1

Cytochrome P-450 Enzyme Inhibitors

Phase 3,Phase 2,Not Applicable

Cytochrome P-450 CYP2C19 Inhibitors

Phase 3,Phase 2,Not Applicable

Steroid Synthesis Inhibitors

Phase 3,Phase 2,Not Applicable

Cytochrome P-450 CYP2C9 Inhibitors

Phase 3,Phase 2,Not Applicable

Hormones

Phase 3,Phase 2,Not Applicable

Anti-Infective Agents

Phase 3,Phase 2,Not Applicable

Hormone Antagonists

Phase 3,Phase 2,Not Applicable

Antifungal Agents

Phase 3,Phase 2,Not Applicable

Neurotransmitter Agents

Phase 3

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 3,Phase 2,Not Applicable

Immunoglobulins, Intravenous

Phase 3

gamma-Globulins

Phase 3

Rho(D) Immune Globulin

Phase 3

Neurotransmitter Uptake Inhibitors

Phase 3

Psychotropic Drugs

Phase 3

Serotonin Agents

Phase 3

Serotonin Uptake Inhibitors

Phase 3

Antidepressive Agents

Phase 3

Serotonin

Investigational, Nutraceutical

Phase 3

50-67-9

5202

Aluminum hydroxide

Approved, Investigational

Phase 2

21645-51-2

Aluminum sulfate

Approved

Phase 2

10043-01-3

Tamoxifen

Approved

Phase 2

10540-29-1

2733526

Amphotericin B

Approved, Investigational

Phase 2

1397-89-3

5280965 14956

Antibodies, Monoclonal

Phase 1, Phase 2

Vaccines

Phase 2,Phase 1

Adjuvants, Immunologic

Phase 2

Gastrointestinal Agents

Phase 2

Anti-Ulcer Agents

Phase 2

Antacids

Phase 2

Estrogen Antagonists

Phase 2

Anti-Bacterial Agents

Phase 2

Liposomal amphotericin B

Phase 2

Antiprotozoal Agents

Phase 2

Cytochrome P-450 CYP3A Inhibitors

Phase 2

Estrogens

Phase 2

Selective Estrogen Receptor Modulators

Phase 2

Estrogen Receptor Modulators

Phase 2

Antineoplastic Agents, Hormonal

Phase 2

Bone Density Conservation Agents

Phase 2

Antiparasitic Agents

Phase 2

Estrogen Receptor Antagonists

Phase 2

Doxycycline

Approved, Investigational, Vet_approved

564-25-0

54671203

Acyclovir

Approved

59277-89-3

2022

Ceftriaxone

Approved

73384-59-5

5479530 5361919

Interventional clinical trials:

(show all 25)

#	Name	Status	NCT ID	Phase	Drugs
1	Investigating the Role of Early Intravenous Immunoglobulin Treatment for Children With Encephalitis	Active, not recruiting	NCT02308982	Phase 3	Immunoglobulins, Intravenous (Privigen);Placebo
2	Cryptococcal Antigen Screening Plus Sertraline	Terminated	NCT03002012	Phase 3	Sertraline;Placebo Oral Tablet;Fluconazole
3	Phase Ib Study of SC Milatuzumab in SLE	Unknown status	NCT01845740	Phase 1, Phase 2	milatuzumab;Placebo
4	A Phase II Clinical Trial for Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children and Infants	Completed	NCT01399853	Phase 2
5	A Booster Dose of Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children	Completed	NCT01734408	Phase 2
6	Treatment With Tamoxifen in Cryptococcal Meningitis	Recruiting	NCT03112031	Phase 2	Tamoxifen;Amphotericin B;Fluconazole
7	A Clinical Trial for Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children and Infants	Completed	NCT01313715	Phase 1
8	A Clinical Trial for Inactivated Vaccine(Vero Cell) Against EV71 in Chinese Healthy Young Adults and Children	Completed	NCT01267903	Phase 1
9	Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020	Completed	NCT00387283	Phase 1	AVI-4020 Injection
10	Study Assessing Tolerability and Safety of AFFITOPE® PD03A in Patients With Early Parkinson's Disease	Completed	NCT02267434	Phase 1
11	Study Assessing Safety and Therapeutic Activity of AFFITOPE® PD01A and PD03A in Patients With Early MSA	Completed	NCT02270489	Phase 1
12	An Exploratory Study of AVI-4020 in Patients With Possible Acute Neuroinvasive West Nile Virus (WNV) Disease	Terminated	NCT00091845	Phase 1	AVI-4020 Injection
13	Etiology of Orphan Community-based Meningitis and Meningo-encephalitis.	Unknown status	NCT02868593	Not Applicable
14	Rijavithi Viral and Mycobacterium PCR Arrays in CNS Infection Study	Completed	NCT00807378
15	Libman-Sacks Endocarditis as a Cause of Neuropsychiatric Systemic Lupus Erythematosus	Completed	NCT00858884	Not Applicable
16	Magnetic Resonance Spectroscopy, Perfusion, and Diffusion Tensor Imaging in Neuropsychiatric Lupus	Completed	NCT00730002	Not Applicable
17	Magnetic Resonance Spectroscopy, Perfusion and Diffusion Tensor Imaging in Neuropsychiatric Lupus	Completed	NCT00723671	Not Applicable
18	Aseptic Meningoencephalitis in Slovenia	Recruiting	NCT02328469		symptomatic therapy;Ceftriaxone or Doxycycline;Acyclovir
19	Driving Reduced AIDS-associated Meningo-encephalitis Mortality	Recruiting	NCT03226379
20	EURopean Study on Encephalitis in Intensive CAre	Recruiting	NCT03144570
21	Research for Angiostrongylus Cantonensis and Costaricensis in French West Indies and French Guiana	Recruiting	NCT03378882
22	Identification and Quantification of HIV CNS Latency Biomarkers	Recruiting	NCT02989285
23	Development of a Novel Glutamate Receptor Ligand for PET Scans in Neuropsychiatric Systemic Lupus Erythematosus	Recruiting	NCT02456168
24	Prevalence of Pathogens in Cerebrospinal Fluid Obtained From Emergency Department Patients	Active, not recruiting	NCT02207647
25	Pre-Antiretroviral Therapy (ART) Cryptococcal Antigen Screening in AIDS	Active, not recruiting	NCT02624453	Not Applicable	Fluconazole;Antiretroviral therapy

Search NIH Clinical Center for Meningoencephalitis

Cochrane evidence based reviews: meningoencephalitis

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Genetic Tests for Meningoencephalitis

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Anatomical Context for Meningoencephalitis

MalaCards organs/tissues related to Meningoencephalitis:

⁴¹

Brain, Pituitary, T Cells, B Cells, Kidney, Liver, Skin

Sources

Publications for Meningoencephalitis

Articles related to Meningoencephalitis:

(show top 50) (show all 1138)

#	Title	Authors	Year
1	Neospora caninum and Ehrlichia canis co-infection in a dog with meningoencephalitis. ( 29406569 )	Aroch I....Chai O.	2018
2	Pharmacodynamics of Flubendazole for Cryptococcal Meningoencephalitis: Repurposing and Reformulation of an Anti-Parasitic Agent for a Neglected Fungal Disease. ( 29311092 )	Nixon G.L....Hope W.	2018
3	Streptococcus agalactiae meningoencephalitis associated with gastroesophageal reflux disease and chronic proton pump inhibitors use, in a 9A month-old infant: a case report. ( 29390957 )	BArrluALiu V....BArrluE9iu R.M.	2018
4	Influenza B-related meningoencephalitis in adults. ( 29930187 )	Yong C.H....Norton G.	2018
5	Cerebrospinal fluid changes in cattle with rabies or with BoHV-5 meningoencephalitis and its correlation with the severity of CNS inflammatory process. ( 29684815 )	Queiroz G.R....LisbA'a J.A.N.	2018
6	Sonographic Diagnosis of Meningoencephalitis in Newborns and Infants. ( 29534259 )	Deeg K.H.	2018
7	Chronic meningoencephalitis caused by Echo virusA 6 in aA patient with common variable immunodeficiency : Successful treatment with pleconaril. ( 29116409 )	RadanoviA8 I....BarA!iA8 B.	2018
8	Estimation of Undiagnosed Naegleria fowleri Primary Amebic Meningoencephalitis, United States<sup>1</sup>. ( 29260676 )	Matanock A....Cope J.R.	2018
9	Systemic Staphylococcus pseudintermedius infection in an arctic fox (Vulpes lagopus) with severe multifocal suppurative meningoencephalitis and nephritis. ( 29887579 )	Iwata K....Shibahara T.	2018
10	A four-year survey (2011-2014) of West Nile virus infection in humans, mosquitoes and birds, including the 2012 meningoencephalitis outbreak in Tunisia. ( 29535295 )	Monastiri A....Serra-Cobo J.	2018
11	Rheumatoid disease: an unusual cause of relapsing meningoencephalitis. ( 29330273 )	Alexander S.K....Cifelli A.	2018
12	Clinical presentation and magnetic resonance imaging findings in 11 dogs with eosinophilic meningoencephalitis of unknown aetiology. ( 29603737 )	Cardy T.J.A....Cornelis I.	2018
13	Lyme Meningoencephalitis Masquerading as Normal Pressure Hydrocephalus. ( 29872598 )	Desai A....Zaghloul A.	2018
14	Nurse's guide to primary amebic meningoencephalitis. ( 29561369 )	Peterson K....Heavey E.	2018
15	An uncommon complication of <i>Listeria monocytogenes</i> infection: Polyradiculoneuritis following Listeria meningoencephalitis. ( 29942763 )	Tebib N....Christin L.	2018
16	Emergency Foramen Magnum Decompression for Tonsillar Herniation Secondary to Meningoencephalitis. ( 29681828 )	Afshari F.T....White E.A.	2018
17	Primary Amebic Meningoencephalitis Associated With Rafting on an Artificial Whitewater River: Case Report and Environmental Investigation. ( 29401275 )	Cope J.R....Hill V.R.	2018
18	Parasitic and zoonotic meningoencephalitis in humans and equids: Current knowledge and the role of <i>Halicephalobus gingivalis</i>. ( 29774297 )		2018
19	Identification and molecular typing of Naegleria fowleri from a patient with primary amebic meningoencephalitis in China. ( 29751112 )		2018
20	Pleocytosis in a patient with relapsing polychondritis accompanied by meningoencephalitis: a case report. ( 29699514 )		2018
21	Acute Disseminated Encephalomyelitis After Herpes Simplex Virus Meningoencephalitis in Adult. ( 29581077 )		2018
22	Cryptococcal meningoencephalitis in patients with mantle cell lymphoma on ibrutinib. ( 29910833 )		2018
23	Co-infection ZIKV and HSV-1 associated with meningoencephalitis: Case report and literature review. ( 29703710 )		2018
24	Clinical Images: A Rare Case of Cryptococcal Meningoencephalitis in an Immunocompetent Patient. ( 29559862 )		2018
25	Mortality from Listeria monocytogenes meningoencephalitis following escalation to alemtuzumab therapy for relapsing-remitting Multiple Sclerosis. ( 29885597 )		2018
26	Report of two cases of tocilizumab induced recurrent meningitis or meningoencephalitis. ( 29366968 )		2018
27	<i>Mycoplasma pneumoniae</i> infection presenting as stroke and meningoencephalitis with aortic and subclavian aneurysms without pulmonary involvement. ( 29326371 )		2018
28	Meningoencephalitis caused by Lactobacillus plantarum - case report. ( 29813007 )		2018
29	Jamestown Canyon virus meningoencephalitis mimicking migraine with aura in a resident of Manitoba. ( 29507158 )		2018
30	Diabetes insipidus secondary to tuberculous meningoencephalitis with hypothalamic involvement extending to the hypophysis: a case report. ( 30517545 )	Santana MF...Ferreira LCL	2018
31	Ehrlichiosis presenting as severe sepsis and meningoencephalitis in an immunocompetent adult. ( 30425837 )	Buzzard SL...Thompson Bastin ML	2018
32	A Fatal Case of Atypical Disseminated Herpes Zoster in a Patient with Meningoencephalitis and Seizures Associated with Steroid Immunosuppression. ( 30270342 )	Fujisato S...Shinozaki T	2018
33	Three children of meningoencephalitis with Kikuchi necrotizing lymphadenitis. ( 29050838 )	Byun JH...Lee YJ	2018
34	Lymphocytic choriomeningitis virus meningoencephalitis in a renal transplant recipient following exposure to mice. ( 30325104 )	Tanveer F...Fishbain J	2018
35	Serological prevalence of toxoplasmosis and neosporosis in dogs diagnosed with suspected meningoencephalitis in the UK. ( 30371939 )	Coelho AM...Guevar J	2018
36	Magnetic resonance imaging features of gelatinous pseudocysts in cryptococcal meningoencephalitis. ( 30374842 )	Zhang P...Wang F	2018
37	Vibrio vulnificus meningoencephalitis in a patient with thalassemia and a splenectomy. ( 30397825 )	He R...Xie H	2018
38	Relapsing Polychondritis with Meningoencephalitis Refractory to Immunosuppressant Therapy. ( 30402308 )	Al-Tabbaa MM...Habal H	2018
39	Acute enteroviral meningoencephalitis as unusual cause of diplopia in pregnancy and puerperium. ( 30441959 )	?erm?kov? S...Fait T	2018
40	Cryptococcal meningoencephalitis in an elderly immunocompetent non-HIV-infected patient. ( 30472030 )	Vandroz E...Legout L	2018
41	Human Chronic Necrotizing Granulomatous Meningoencephalitis: A Novel Case Report. ( 30483106 )	Taddonio AP...Baldwin KJ	2018
42	Phenotypic screens reveal posaconazole as rapidly cidal combination partner for treatment of Primary Amoebic Meningoencephalitis. ( 30358879 )	Colon BL...Kyle DE	2018
43	Immunohistochemical studies on meningoencephalitis in feline infectious peritonitis (FIP). ( 30333381 )	Wang H...Nakayama H	2018
44	Atypical Anti-MOG syndrome with aseptic meningoencephalitis and pseudotumor cerebri-like presentations. ( 30300850 )	Narayan RN...Greenberg B	2018
45	A Predominant Clonal Thromboembolic Meningoencephalitis Group of Histophilus somni Assigned by Major Outer Membrane Protein Gene Sequencing and Pulsed-Field Gel Electrophoresis. ( 30283793 )	Ueno Y...Katsuda K	2018
46	An Autopsy Case of Edwardsiella tarda Meningoencephalitis. ( 30283323 )	Makino T...Kamitsukasa I	2018
47	Closing the Brief Case: A 10-Year-Old Girl with Meningoencephalitis. ( 30254111 )	Madigan T...Binnicker MJ	2018
48	The Brief Case: A 10-Year-Old Girl with Meningoencephalitis. ( 30254110 )	Madigan T...Binnicker MJ	2018
49	Clinical case report on treatment of Listeria monocytogenes meningoencephalitis: Intrathecal injection. ( 30214776 )	Pan XB...Fan HN	2018
50	Rapid Therapeutic Response of Eosinophilic Meningoencephalitis in a Toddler With Baylisascaris procyonis Infection. ( 30193023 )	Muganda GN...Nelson AM	2018

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Genes for Meningoencephalitis

Genes related to Meningoencephalitis (0 elite genes):

(show all 16)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	CARD9	Caspase Recruitment Domain Family Member 9	Protein Coding	22.4	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	ALB	Albumin	Protein Coding	22.17	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	IL6	Interleukin 6	Protein Coding	21.52	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	APP	Amyloid Beta Precursor Protein	Protein Coding	21.44	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	14997933 19675171
5	CD79A	CD79a Molecule	Protein Coding	20.53	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	CD40LG	CD40 Ligand	Protein Coding	20.18	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	B2M	Beta-2-Microglobulin	Protein Coding	19.97	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	TLR9	Toll Like Receptor 9	Protein Coding	19.95	DISEASES inferred ¹⁵ ¹⁵
9	CCL5	C-C Motif Chemokine Ligand 5	Protein Coding	18.75	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	18239321 9846826
10	MBP	Myelin Basic Protein	Protein Coding	18.01	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	1690527 16549802
11	CREBBP	CREB Binding Protein	Protein Coding	16.54	GeneCards inferred via : Publications (show sections)
12	SLC17A5	Solute Carrier Family 17 Member 5	Protein Coding	16.54	GeneCards inferred via : Publications (show sections)
13	TAC1	Tachykinin Precursor 1	Protein Coding	16.54	GeneCards inferred via : Publications (show sections)
14	TACR3	Tachykinin Receptor 3	Protein Coding	16.54	GeneCards inferred via : Publications (show sections)
15	MECP2	Methyl-CpG Binding Protein 2	Protein Coding	16.54	GeneCards inferred via : Publications (show sections)
16	CHKB	Choline Kinase Beta	Protein Coding	16.54	GeneCards inferred via : Publications (show sections)

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Variations for Meningoencephalitis

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Expression for Meningoencephalitis

Search GEO for disease gene expression data for Meningoencephalitis.

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Pathways for Meningoencephalitis

Pathways related to Meningoencephalitis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Tuberculosis ³⁷	11.88	CARD9 CREBBP IL6 TLR9
2	C-type lectin receptor signaling pathway ³⁷ Show member pathways Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways ⁶⁵	11.69	CARD9 CREBBP IL6 TLR9
3	NF-kappaB Signaling ⁴	11.61	B2M CARD9 CCL5 CD40LG CD79A TLR9
4	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways ¹	11.47	CREBBP IL6 MECP2 TAC1
5	Lung fibrosis ¹	11.34	CCL5 IL6 MECP2
6	Malaria ³⁷	11.12	CD40LG IL6 TLR9

Sources

GO Terms for Meningoencephalitis

Cellular components related to Meningoencephalitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular region	GO:0005576	9.76	ALB APP B2M CCL5 CD40LG IL6
2	endoplasmic reticulum lumen	GO:0005788	9.26	ALB APP B2M IL6
3	extracellular space	GO:0005615	9.23	ALB APP B2M CCL5 CD40LG IL6

Biological processes related to Meningoencephalitis according to GeneCards Suite gene sharing:

(show all 15)

#	Name	GO ID	Score	Top Affiliating Genes
1	neuron projection development	GO:0031175	9.72	APP IL6 MECP2
2	cellular protein metabolic process	GO:0044267	9.71	ALB APP B2M IL6
3	positive regulation of JNK cascade	GO:0046330	9.65	APP CARD9 TLR9
4	inflammatory response	GO:0006954	9.55	CCL5 CD40LG IL6 TAC1 TLR9
5	positive regulation of chemokine production	GO:0032722	9.54	IL6 TLR9
6	positive regulation of T cell proliferation	GO:0042102	9.54	CCL5 CD40LG IL6
7	positive regulation of T cell migration	GO:2000406	9.52	APP CCL5
8	positive regulation of acute inflammatory response	GO:0002675	9.51	IL6 TAC1
9	positive regulation of interleukin-6 production	GO:0032755	9.5	CARD9 IL6 TLR9
10	response to molecule of bacterial origin	GO:0002237	9.49	B2M TLR9
11	tachykinin receptor signaling pathway	GO:0007217	9.46	TAC1 TACR3
12	response to peptidoglycan	GO:0032494	9.43	CARD9 IL6
13	tumor necrosis factor production	GO:0032640	9.26	APP TLR9
14	positive regulation of NF-kappaB transcription factor activity	GO:0051092	9.26	APP CD40LG IL6 TLR9
15	immune response	GO:0006955	9.1	B2M CCL5 CD40LG IL6 MBP TLR9

Molecular functions related to Meningoencephalitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	siRNA binding	GO:0035197	8.62	MECP2 TLR9

Sources

Sources for Meningoencephalitis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia