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MCID: MNN009
MIFTS: 49

Meningoencephalitis

Categories: Neuronal diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Meningoencephalitis

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MalaCards integrated aliases for Meningoencephalitis:

Name: Meningoencephalitis 12 55 44 15 73

Classifications:

MalaCards categories:
Anatomical: Neuronal diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:10554
ICD10 33 A69.22 G04
MeSH 44 D008590
NCIt 50 C34813
SNOMED-CT 68 7125002
UMLS 73 C0025309
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Summaries for Meningoencephalitis

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Disease Ontology : 12 A central nervous system disease that involves encephalitis which occurs along with meningitis.

MalaCards based summary : Meningoencephalitis is related to parotitis and coccidioidomycosis. An important gene associated with Meningoencephalitis is CD40LG (CD40 Ligand), and among its related pathways/superpathways are Neuroscience and NF-KappaB Family Pathway. The drugs Fluconazole and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include brain, pituitary and bone, and related phenotypes are homeostasis/metabolism and cellular

Wikipedia : 76 Meningoencephalitis (/mɪˌnɪŋɡoʊɛnˌsɛfəˈlaɪtɪs, -ˌnɪndʒoʊ-, -ən-, -ˌkɛ-/; from Greek μῆνιγξ meninx,... more...

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Related Diseases for Meningoencephalitis

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Diseases related to Meningoencephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 406)
# Related Disease Score Top Affiliating Genes
1 parotitis 30.8 ALB CD79A
2 coccidioidomycosis 30.3 CARD9 CD40LG
3 syphilis 30.2 B2M CD40LG CD79A
4 chlamydia 30.2 CD40LG CD79A IL6
5 meningitis 30.1 ALB CD40LG IL6 TLR9
6 otitis media 30.0 ALB CD40LG CD79A IL6
7 peritonitis 30.0 ALB B2M IL6
8 acquired immunodeficiency syndrome 29.9 ALB B2M CD40LG CD79A IL6
9 progressive multifocal leukoencephalopathy 29.6 CD40LG MBP MECP2
10 guillain-barre syndrome 29.4 ALB CD40LG CD79A MBP
11 rabies 29.2 ALB CCL5 CD40LG
12 disease of mental health 29.2 APP BDNF MECP2
13 exanthem 29.2 CD40LG CD79A IL6 TLR9
14 chikungunya 29.2 CCL5 CD40LG IL6
15 toxoplasmosis 29.1 CD40LG CD79A IL6 TLR9
16 pneumonia 29.1 CCL5 CD40LG IL6 TLR9
17 common variable immunodeficiency 29.1 CD40LG CD79A IL6 TLR9
18 relapsing-remitting multiple sclerosis 28.4 BDNF CCL5 MBP
19 human immunodeficiency virus type 1 28.2 B2M CCL5 GDNF IL6
20 rhinitis 28.0 CCL5 NGF TLR9
21 systemic lupus erythematosus 27.9 ALB CCL5 CD40LG CD79A IL6 TLR9
22 multiple sclerosis 26.5 BDNF CCL5 IL6 MBP NGF TLR9
23 asthma 26.1 BDNF CCL5 CD40LG CD79A IL6 NGF
24 primary amebic meningoencephalitis 12.2
25 lymphocytic choriomeningitis 11.7
26 tick-borne encephalitis 11.2
27 trichinosis 11.2
28 selective igg deficiency disease 11.0 CD40LG CD79A
29 c1q nephropathy 11.0 CD40LG CD79A
30 ostertagiasis 11.0 ALB CD79A
31 alpha chain disease 11.0 CD40LG CD79A
32 brill-zinsser disease 11.0 CD40LG CD79A
33 colorado tick fever 11.0 ALB CD40LG
34 exudative glomerulonephritis 11.0 CD40LG CD79A
35 dermatitis, atopic, 3 11.0 ALB CD79A
36 salpingo-oophoritis 11.0 CD40LG CD79A
37 early yaws 11.0 CD40LG CD79A
38 ventilation pneumonitis 11.0 CD40LG CD79A
39 chronic interstitial cystitis 11.0 CD40LG CD79A
40 axillary adenitis 11.0 CD40LG CD79A
41 cryofibrinogenemia 11.0 CD40LG CD79A
42 trichostrongyloidiasis 10.9 CD40LG CD79A
43 subacute bacterial endocarditis 10.9 CD40LG CD79A
44 heterophyiasis 10.9 CD40LG CD79A
45 immunoglobulin g deficiency 10.9 CD40LG CD79A
46 plasmodium malariae malaria 10.9 ALB CD40LG
47 orbital granuloma 10.9 CD40LG CD79A
48 transient hypogammaglobulinemia of infancy 10.9 CD40LG CD79A
49 hyperglobulinemic purpura 10.9 CD40LG CD79A
50 gastroduodenitis 10.9 CD40LG CD79A

Graphical network of the top 20 diseases related to Meningoencephalitis:



Diseases related to Meningoencephalitis
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Symptoms & Phenotypes for Meningoencephalitis

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MGI Mouse Phenotypes related to Meningoencephalitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.22 MECP2 NGF TLR9 MBP CD79A B2M
2 cellular MP:0005384 10.2 MBP MECP2 TLR9 IL6 CD79A B2M
3 hematopoietic system MP:0005397 10.13 MBP TLR9 IL6 CD79A B2M GDNF
4 immune system MP:0005387 10.11 MBP MECP2 TLR9 IL6 CD79A B2M
5 mortality/aging MP:0010768 10 MBP MECP2 NGF TLR9 IL6 APP
6 nervous system MP:0003631 9.9 MBP MECP2 NGF IL6 CD79A B2M
7 integument MP:0010771 9.87 MECP2 NGF IL6 CD40LG APP B2M
8 renal/urinary system MP:0005367 9.43 TLR9 IL6 CD40LG CD79A GDNF ALB
9 reproductive system MP:0005389 9.23 MBP MECP2 IL6 CD40LG APP B2M
Sources

Drugs & Therapeutics for Meningoencephalitis

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Drugs for Meningoencephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 59)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluconazole Approved, Investigational Phase 3,Phase 2,Not Applicable 86386-73-4 3365
2
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 22916-47-8 4189
3
Sertraline Approved Phase 3 79617-96-2 68617
4 Antibodies Phase 3,Phase 1,Phase 2
5 Immunoglobulins Phase 3,Phase 1,Phase 2
6 Antifungal Agents Phase 3,Phase 2,Not Applicable
7 Anti-Infective Agents Phase 3,Phase 2,Not Applicable
8 Cytochrome P-450 CYP2C9 Inhibitors Phase 3,Phase 2,Not Applicable
9 Cytochrome P-450 Enzyme Inhibitors Phase 3,Phase 2,Not Applicable
10 Hormone Antagonists Phase 3,Phase 2,Not Applicable
11 Hormones Phase 3,Phase 2,Not Applicable
12 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Not Applicable
13 Neurotransmitter Agents Phase 3
14 Steroid Synthesis Inhibitors Phase 3,Phase 2,Not Applicable
15 gamma-Globulins Phase 3
16 Immunoglobulins, Intravenous Phase 3
17 Rho(D) Immune Globulin Phase 3
18 Antidepressive Agents Phase 3
19 Neurotransmitter Uptake Inhibitors Phase 3
20 Psychotropic Drugs Phase 3
21 Serotonin Agents Phase 3
22 Serotonin Uptake Inhibitors Phase 3
23
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
24
Aluminum hydroxide Approved, Investigational Phase 2 21645-51-2
25
Aluminum sulfate Approved Phase 2 10043-01-3
26
Amphotericin B Approved, Investigational Phase 2 1397-89-3 14956 5280965
27
Tamoxifen Approved Phase 2 10540-29-1 2733526
28 Antibodies, Monoclonal Phase 1, Phase 2
29 Vaccines Phase 2,Phase 1
30 Adjuvants, Immunologic Phase 2
31 Antacids Phase 2
32 Anti-Ulcer Agents Phase 2
33 Gastrointestinal Agents Phase 2
34 Anti-Bacterial Agents Phase 2
35 Antineoplastic Agents, Hormonal Phase 2
36 Antiparasitic Agents Phase 2
37 Antiprotozoal Agents Phase 2
38 Bone Density Conservation Agents Phase 2
39 Cytochrome P-450 CYP3A Inhibitors Phase 2
40 Estrogen Antagonists Phase 2
41 Estrogen Receptor Modulators Phase 2
42 Estrogens Phase 2
43 Liposomal amphotericin B Phase 2
44 Selective Estrogen Receptor Modulators Phase 2
45
Acyclovir Approved 59277-89-3 2022
46
Ceftriaxone Approved 73384-59-5 5479530 5361919
47
Dopamine Approved 51-61-6, 62-31-7 681
48
Doxycycline Approved, Investigational, Vet_approved 564-25-0 54671203
49
Glutamic Acid Approved, Nutraceutical 56-86-0 33032
50 Antibiotics, Antitubercular

Interventional clinical trials:

(show all 25)
# Name Status NCT ID Phase Drugs
1 Investigating the Role of Early Intravenous Immunoglobulin Treatment for Children With Encephalitis Active, not recruiting NCT02308982 Phase 3 Immunoglobulins, Intravenous (Privigen);Placebo
2 Cryptococcal Antigen Screening Plus Sertraline Terminated NCT03002012 Phase 3 Sertraline;Placebo Oral Tablet;Fluconazole
3 Phase Ib Study of SC Milatuzumab in SLE Unknown status NCT01845740 Phase 1, Phase 2 milatuzumab;Placebo
4 A Phase II Clinical Trial for Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children and Infants Completed NCT01399853 Phase 2
5 A Booster Dose of Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children Completed NCT01734408 Phase 2
6 Treatment With Tamoxifen in Cryptococcal Meningitis Recruiting NCT03112031 Phase 2 Tamoxifen;Amphotericin B;Fluconazole
7 A Clinical Trial for Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children and Infants Completed NCT01313715 Phase 1
8 A Clinical Trial for Inactivated Vaccine(Vero Cell) Against EV71 in Chinese Healthy Young Adults and Children Completed NCT01267903 Phase 1
9 Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020 Completed NCT00387283 Phase 1 AVI-4020 Injection
10 Study Assessing Tolerability and Safety of AFFITOPE® PD03A in Patients With Early Parkinson's Disease Completed NCT02267434 Phase 1
11 Study Assessing Safety and Therapeutic Activity of AFFITOPE® PD01A and PD03A in Patients With Early MSA Completed NCT02270489 Phase 1
12 An Exploratory Study of AVI-4020 in Patients With Possible Acute Neuroinvasive West Nile Virus (WNV) Disease Terminated NCT00091845 Phase 1 AVI-4020 Injection
13 Rijavithi Viral and Mycobacterium PCR Arrays in CNS Infection Study Completed NCT00807378
14 Libman-Sacks Endocarditis as a Cause of Neuropsychiatric Systemic Lupus Erythematosus Completed NCT00858884 Not Applicable
15 Magnetic Resonance Spectroscopy, Perfusion, and Diffusion Tensor Imaging in Neuropsychiatric Lupus Completed NCT00730002 Not Applicable
16 Magnetic Resonance Spectroscopy, Perfusion and Diffusion Tensor Imaging in Neuropsychiatric Lupus Completed NCT00723671 Not Applicable
17 Etiology of Orphan Community-based Meningitis and Meningo-encephalitis. Recruiting NCT02868593 Not Applicable
18 Aseptic Meningoencephalitis in Slovenia Recruiting NCT02328469 symptomatic therapy;Ceftriaxone or Doxycycline;Acyclovir
19 Driving Reduced AIDS-associated Meningo-encephalitis Mortality Recruiting NCT03226379
20 EURopean Study on Encephalitis in Intensive CAre Recruiting NCT03144570
21 Research for Angiostrongylus Cantonensis and Costaricensis in French West Indies and French Guiana Recruiting NCT03378882
22 Identification and Quantification of HIV CNS Latency Biomarkers Recruiting NCT02989285
23 Development of a Novel Glutamate Receptor Ligand for PET Scans in Neuropsychiatric Systemic Lupus Erythematosus Recruiting NCT02456168
24 Prevalence of Pathogens in Cerebrospinal Fluid Obtained From Emergency Department Patients Active, not recruiting NCT02207647
25 Pre-Antiretroviral Therapy (ART) Cryptococcal Antigen Screening in AIDS Active, not recruiting NCT02624453 Not Applicable Fluconazole;Antiretroviral therapy

Search NIH Clinical Center for Meningoencephalitis

Cochrane evidence based reviews: meningoencephalitis

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Genetic Tests for Meningoencephalitis

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Anatomical Context for Meningoencephalitis

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MalaCards organs/tissues related to Meningoencephalitis:

41
Brain, Pituitary, Bone, Skin, T Cells, Kidney, B Cells
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Publications for Meningoencephalitis

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Articles related to Meningoencephalitis:

(show top 50) (show all 815)
# Title Authors Year
1
Neospora caninum and Ehrlichia canis co-infection in a dog with meningoencephalitis. ( 29406569 )
2018
2
Pharmacodynamics of Flubendazole for Cryptococcal Meningoencephalitis: Repurposing and Reformulation of an Anti-Parasitic Agent for a Neglected Fungal Disease. ( 29311092 )
2018
3
Streptococcus agalactiae meningoencephalitis associated with gastroesophageal reflux disease and chronic proton pump inhibitors use, in a 9A month-old infant: a case report. ( 29390957 )
2018
4
Influenza B-related meningoencephalitis in adults. ( 29930187 )
2018
5
Cerebrospinal fluid changes in cattle with rabies or with BoHV-5 meningoencephalitis and its correlation with the severity of CNS inflammatory process. ( 29684815 )
2018
6
Sonographic Diagnosis of Meningoencephalitis in Newborns and Infants. ( 29534259 )
2018
7
Chronic meningoencephalitis caused by Echo virusA 6 in aA patient with common variable immunodeficiency : Successful treatment with pleconaril. ( 29116409 )
2018
8
Estimation of Undiagnosed Naegleria fowleri Primary Amebic Meningoencephalitis, United States<sup>1</sup>. ( 29260676 )
2018
9
Systemic Staphylococcus pseudintermedius infection in an arctic fox (Vulpes lagopus) with severe multifocal suppurative meningoencephalitis and nephritis. ( 29887579 )
2018
10
A four-year survey (2011-2014) of West Nile virus infection in humans, mosquitoes and birds, including the 2012 meningoencephalitis outbreak in Tunisia. ( 29535295 )
2018
11
Rheumatoid disease: an unusual cause of relapsing meningoencephalitis. ( 29330273 )
2018
12
Clinical presentation and magnetic resonance imaging findings in 11 dogs with eosinophilic meningoencephalitis of unknown aetiology. ( 29603737 )
2018
13
Lyme Meningoencephalitis Masquerading as Normal Pressure Hydrocephalus. ( 29872598 )
2018
14
Nurse's guide to primary amebic meningoencephalitis. ( 29561369 )
2018
15
An uncommon complication of <i>Listeria monocytogenes</i> infection: Polyradiculoneuritis following Listeria meningoencephalitis. ( 29942763 )
2018
16
Emergency Foramen Magnum Decompression for Tonsillar Herniation Secondary to Meningoencephalitis. ( 29681828 )
2018
17
Primary Amebic Meningoencephalitis Associated With Rafting on an Artificial Whitewater River: Case Report and Environmental Investigation. ( 29401275 )
2018
18
Parasitic and zoonotic meningoencephalitis in humans and equids: Current knowledge and the role of <i>Halicephalobus gingivalis</i>. ( 29774297 )
2018
19
Identification and molecular typing of Naegleria fowleri from a patient with primary amebic meningoencephalitis in China. ( 29751112 )
2018
20
Pleocytosis in a patient with relapsing polychondritis accompanied by meningoencephalitis: a case report. ( 29699514 )
2018
21
Acute Disseminated Encephalomyelitis After Herpes Simplex Virus Meningoencephalitis in Adult. ( 29581077 )
2018
22
Cryptococcal meningoencephalitis in patients with mantle cell lymphoma on ibrutinib. ( 29910833 )
2018
23
Co-infection ZIKV and HSV-1 associated with meningoencephalitis: Case report and literature review. ( 29703710 )
2018
24
Clinical Images: A Rare Case of Cryptococcal Meningoencephalitis in an Immunocompetent Patient. ( 29559862 )
2018
25
Mortality from Listeria monocytogenes meningoencephalitis following escalation to alemtuzumab therapy for relapsing-remitting Multiple Sclerosis. ( 29885597 )
2018
26
Report of two cases of tocilizumab induced recurrent meningitis or meningoencephalitis. ( 29366968 )
2018
27
<i>Mycoplasma pneumoniae</i> infection presenting as stroke and meningoencephalitis with aortic and subclavian aneurysms without pulmonary involvement. ( 29326371 )
2018
28
Meningoencephalitis caused by Lactobacillus plantarum - case report. ( 29813007 )
2018
29
Jamestown Canyon virus meningoencephalitis mimicking migraine with aura in a resident of Manitoba. ( 29507158 )
2018
30
Septic Shock, Meningoencephalitis and Multiple Pulmonary Emboli: Case Report of an Uncommon Clinical Presentation of Ventricular Septal Defect Acute Infective Endocarditis. ( 29762935 )
2017
31
CD4<sup>+</sup>T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during<i>Cryptococcus neoformans</i>Meningoencephalitis. ( 29162707 )
2017
32
A rare case of fatal meningoencephalitis with septic thromboembolism due to otitis media: a forensic case and review of literature. ( 28739620 )
2017
33
Meningoencephalitis in a Royal Marine after skinning reindeer in Norway. ( 29151040 )
2017
34
Snowshoe Hare Virus Causing Meningoencephalitis in a Young Adult From Northern Manitoba, Canada. ( 28948178 )
2017
35
Naturally Acquired Canine Herpesvirus-Associated Meningoencephalitis. ( 28655291 )
2017
36
Case Report: Zika Virus Meningoencephalitis and Myelitis and Associated Magnetic Resonance Imaging Findings. ( 28829736 )
2017
37
A novel cause of chronic viral meningoencephalitis: Cache Valley virus. ( 28628941 )
2017
38
SARCOCYSTIS NEURONA-ASSOCIATED MENINGOENCEPHALITIS IN A PACIFIC WALRUS ( ODOBENDUS ROSMARUS DIVERGENS). ( 29297810 )
2017
39
Predisposing Factors Responsible for the Occurrence of Bacterial Purulent Meningoencephalitis ( 29120154 )
2017
40
Cryptococcal antigen negative meningoencephalitis in HIV/AIDS. ( 28784461 )
2017
41
Magnetic Resonance Imaging Findings of Mumps Meningoencephalitis with Bilateral Hippocampal Lesions without Preceding Acute Parotitis: A Case Report. ( 28246518 )
2017
42
Cryptococcal Meningoencephalitis Complicated by Subdural Empyema in an 8-Year-Old Girl With Neonatal-Onset Multisystem Inflammatory Disease Syndrome: A Rare Sequela. ( 28992083 )
2017
43
Biofilm is associated with chronic streptococcal meningoencephalitis in fish. ( 27890651 )
2017
44
Henry II of France (1519-1559) and his death from meningoencephalitis following a cranial trauma. ( 28712901 )
2017
45
A Case Report of Nonvasculitic Autoimmune Inflammatory Meningoencephalitis with Sensory Ganglionopathy: A Rare Presentation of SjAPgren Syndrome. ( 28182102 )
2017
46
CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). ( 29284029 )
2017
47
Relapsing polychondritis with meningoencephalitis. ( 28207003 )
2017
48
RETROSPECTIVE STUDY EVALUATING ASSOCIATIONS BETWEEN MIDLINE BRAIN SHIFT ON MAGNETIC RESONANCE IMAGING AND SURVIVAL IN DOGS DIAGNOSED WITH MENINGOENCEPHALITIS OF UNKNOWN ETIOLOGY. ( 27774741 )
2017
49
Zika Virus Meningoencephalitis. ( 28778266 )
2017
50
Septicemia and meningoencephalitis caused by Listeria monocytogenes in two neonatal llamas. ( 28677403 )
2017
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Variations for Meningoencephalitis

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Expression for Meningoencephalitis

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Search GEO for disease gene expression data for Meningoencephalitis.
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Pathways for Meningoencephalitis

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Pathways related to Meningoencephalitis according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Neuroscience 4
12.31 APP MBP MECP2 NGF
2
NF-KappaB Family Pathway 64
Show member pathways
 12.27 BDNF CD40LG IL6 NGF TLR9
3
Immune response IFN gamma signaling pathway 22
Show member pathways
 11.81 BDNF CCL5 IL6 NGF
4
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 1
11.67 BDNF IL6 MECP2 NGF
5
NF-kappaB Signaling 4
11.61 B2M CARD9 CCL5 CD40LG CD79A TLR9
6
Neural Stem Cell Differentiation Pathways and Lineage-specific Markers 65
11.53 BDNF GDNF NGF
7
p75(NTR)-mediated signaling 1
Show member pathways
 11.43 APP BDNF NGF
8
Lung fibrosis 1
11.38 CCL5 IL6 MECP2
9
MECP2 and Associated Rett Syndrome 1
11.34 BDNF MBP MECP2
10
Spinal Cord Injury 1
11.34 BDNF GDNF IL6 MBP
11
Malaria 37
11.19 CD40LG IL6 TLR9
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GO Terms for Meningoencephalitis

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Cellular components related to Meningoencephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 ALB APP B2M BDNF CCL5 CD40LG
2 endoplasmic reticulum lumen GO:0005788 9.46 ALB APP B2M IL6
3 extracellular space GO:0005615 9.32 ALB APP B2M BDNF CCL5 CD40LG

Biological processes related to Meningoencephalitis according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.97 ALB CD40LG GDNF IL6 NGF
2 immune response GO:0006955 9.92 B2M CCL5 CD40LG IL6 MBP
3 cellular protein metabolic process GO:0044267 9.8 ALB APP B2M IL6
4 memory GO:0007613 9.72 BDNF MECP2 NGF
5 positive regulation of JNK cascade GO:0046330 9.71 APP CARD9 TLR9
6 positive regulation of T cell proliferation GO:0042102 9.65 CCL5 CD40LG IL6
7 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.62 APP CD40LG IL6 TLR9
8 positive regulation of chemokine production GO:0032722 9.61 IL6 TLR9
9 nerve development GO:0021675 9.61 BDNF NGF
10 adult locomotory behavior GO:0008344 9.61 APP GDNF MECP2
11 positive regulation of T cell migration GO:2000406 9.6 APP CCL5
12 locomotion GO:0040011 9.59 BDNF NGF
13 response to molecule of bacterial origin GO:0002237 9.58 B2M TLR9
14 nerve growth factor signaling pathway GO:0038180 9.58 BDNF NGF
15 positive regulation of interleukin-6 production GO:0032755 9.58 CARD9 IL6 TLR9
16 positive regulation of collateral sprouting GO:0048672 9.56 BDNF NGF
17 neuron projection development GO:0031175 9.56 APP GDNF IL6 MECP2
18 response to peptidoglycan GO:0032494 9.51 CARD9 IL6
19 positive regulation of receptor binding GO:1900122 9.46 B2M BDNF
20 negative regulation of neuron apoptotic process GO:0043524 9.46 BDNF GDNF MECP2 NGF
21 tumor necrosis factor production GO:0032640 9.37 APP TLR9
22 peripheral nervous system development GO:0007422 9.13 BDNF GDNF NGF
23 regulation of signaling receptor activity GO:0010469 9.1 BDNF CCL5 CD40LG GDNF IL6 NGF

Molecular functions related to Meningoencephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 siRNA binding GO:0035197 8.96 MECP2 TLR9
2 growth factor activity GO:0008083 8.92 BDNF GDNF IL6 NGF
Sources

Sources for Meningoencephalitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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