MCID: MNN022
MIFTS: 21

Meningoencephalocele

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Meningoencephalocele

MalaCards integrated aliases for Meningoencephalocele:

Name: Meningoencephalocele 52
Meningo-Encephalocele 71
Encephalomeningocele 52

Classifications:



External Ids:

UMLS 71 C3825985

Summaries for Meningoencephalocele

NIH Rare Diseases : 52 Meningoencephalocele is a type of encephalocele , which is an abnormal sac of fluid, brain tissue , and meninges (membranes that cover the brain and spinal cord) that extends through a defect in the skull. There are two main types of meningoencephalocele, which are named according to the location of the sac. The frontoethmoidal type is located at the frontal and ethmoid bones while the occipital type is located at the occipital bone . Hydrocephalus , abnormalities of the eyeball and tear duct, and other findings have been associated with the condition. Some affected individuals have intellectual or physical disabilities while others have normal development and abilities. The condition is typically congenital (present at birth) but has been reported to develop by chance in older individuals in rare cases. The underlying cause of the condition is uncertain, but environmental factors are thought to play a role. Treatment depends on the size, location and severity of the defect but mainly includes magnetic resonance imaging (MRI) to determine the severity of the defect, followed by surgery to repair it.

MalaCards based summary : Meningoencephalocele, also known as meningo-encephalocele, is related to podder-tolmie syndrome and meckel syndrome, type 2. An important gene associated with Meningoencephalocele is RMND5A (Required For Meiotic Nuclear Division 5 Homolog A). Affiliated tissues include brain, bone and spinal cord.

Wikipedia : 74 Encephalocele is a neural tube defect characterized by sac-like protrusions of the brain and the... more...

Related Diseases for Meningoencephalocele

Diseases related to Meningoencephalocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 144)
# Related Disease Score Top Affiliating Genes
1 podder-tolmie syndrome 11.6
2 meckel syndrome, type 2 11.3
3 encephalocele 10.6
4 meningocele 10.5
5 meningitis 10.5
6 hydrocephalus 10.4
7 intracranial hypertension 10.4
8 cerebrospinal fluid leak 10.4
9 mollaret meningitis 10.4
10 hypertelorism 10.3
11 exophthalmos 10.3
12 cleft palate, isolated 10.2
13 telecanthus 10.2
14 neurofibromatosis 10.2
15 cleft lip 10.2
16 bacterial meningitis 10.2
17 craniosynostosis 10.2
18 glioma 10.2
19 cleft lip/palate 10.2
20 glial tumor 10.2
21 frontal encephalocele 10.1
22 basal encephalocele 10.1
23 otitis media 10.1
24 neural tube defects 10.1
25 strabismus 10.1
26 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.1
27 temporal lobe epilepsy 10.1
28 mechanical strabismus 10.1
29 neurofibroma 10.1
30 head injury 10.1
31 crouzon syndrome 10.0
32 frontonasal dysplasia 1 10.0
33 dandy-walker syndrome 10.0
34 corpus callosum, agenesis of, with facial anomalies and cerebellar ataxia 10.0
35 ptosis 10.0
36 myelomeningocele 10.0
37 superior semicircular canal dehiscence 10.0
38 benign teratoma 10.0
39 microcephaly 10.0
40 ventricular septal defect 10.0
41 heart septal defect 10.0
42 cystic teratoma 10.0
43 empty sella syndrome 10.0
44 rhinitis 10.0
45 holoprosencephaly 10.0
46 plexiform neurofibroma 10.0
47 pituitary gland disease 10.0
48 mature teratoma 10.0
49 eye disease 10.0
50 dwarfism 10.0

Graphical network of the top 20 diseases related to Meningoencephalocele:



Diseases related to Meningoencephalocele

Symptoms & Phenotypes for Meningoencephalocele

Drugs & Therapeutics for Meningoencephalocele

Search Clinical Trials , NIH Clinical Center for Meningoencephalocele

Genetic Tests for Meningoencephalocele

Anatomical Context for Meningoencephalocele

MalaCards organs/tissues related to Meningoencephalocele:

40
Brain, Bone, Spinal Cord, Eye, Kidney, Pituitary, Skin

Publications for Meningoencephalocele

Articles related to Meningoencephalocele:

(show top 50) (show all 484)
# Title Authors PMID Year
1
Spontaneous symptomatic orbital meningoencephalocele in an adult patient. Case report and review of the literature. 61
32409212 2020
2
Otogenic Pneumocephalus After Tegmen Bone Reconstruction: A Case Report. 61
32543228 2020
3
Spontaneous transethmoidal meningoencephalocele presenting in the form of recurrent unilateral nasal discharge: discussion of the diagnosis and endoscopic surgical management. 61
32404373 2020
4
Endoscopic management of congenital nasal meningoencephaloceles: a short series of 15 paediatric cases. 61
32382868 2020
5
Management of tegmen defects with mastoid and epitympanic obliteration using S53P4 bioactive glass. 61
32337361 2020
6
Endonasal endoscopic management of the craniopharyngeal canal meningoencephalocele using a nasoseptal flap in a 6-month-old infant. 61
32270272 2020
7
How long is the tail end of the learning curve? Results from 1000 consecutive endoscopic endonasal skull base cases following the initial 200 cases. 61
32032942 2020
8
Endoscopic Surgical Repair of a Giant, Postoperative, Neglected Meningoencephalocele. 61
32133261 2020
9
Whole exome sequencing identified a homozygous novel variant in CEP290 gene causes Meckel syndrome. 61
31840411 2020
10
Subventricular glial nodules in neurofibromatosis 1 with craniofacial dysmorphism and occipital meningoencephalocele. 61
31799455 2019
11
Endonasal endoscopic skullbase surgery in children. 61
31079184 2019
12
Streptococcus Oralis meningitis from right sphenoid Meningoencephalocele and cerebrospinal fluid leak. 61
31711423 2019
13
The reconstruction of skull base defects in infants using pedicled nasoseptal flap-a review of four cases. 61
30968177 2019
14
Surgical correction of a meningoencephalocele in a thoroughbred filly. 61
31135063 2019
15
Endoscopic endonasal resection of congenital trans-sphenoidal meningoencephalocele with extension to the epipharynx in early childhood: a case report. 61
32127849 2019
16
Incidental spontaneous CSF fistula with pterygoid process meningoencephalocele. 61
31380824 2019
17
Nasal Framework Osteotomy: An Innovative Approach to Manage an Extremely Long Nose With Meningoencephalocele. 61
30851254 2019
18
Clinical, radiological features and surgical strategies for 23 NF1 patients with intraorbital meningoencephalocele. 61
30868483 2019
19
Dermoid cyst with cerebellar meningoencephalocele at different locations accompanied by posterior fossa abnormalities: case report. 61
30156600 2019
20
Surgical Implications of the Anteriorly Displaced Segments of the Anterior Cerebral Artery in the Management of Frontoethmoidal Meningoencephalocele. 61
31048610 2019
21
Surgical management of meningoencephalocele in temporal bone associated with pharmacoresistant epilepsy: report of two cases. 61
29179608 2019
22
Delayed presentation of morning glory disc anomaly and transsphenoidal encephalocele: A management dilemma. 61
31312233 2019
23
Giant meningoencephalocele with Arnold-Chiari type III malformation and anaesthetic challenges: A rare case report. 61
31007660 2019
24
Iatrogenic meningoencephalocele after traumatic perforation of the cribriform plate during nasal intubation of a preterm infant. 61
30611097 2019
25
Temporal bone meningoencephaloceles and cerebrospinal fluid leaks: experience in a tertiary care hospital. 61
30777139 2019
26
Outcome of Endoscopic Cerebrospinal Fluid Rhinorrhoea Repair: An Institutional Study. 61
30906718 2019
27
Vascular malformation of the sphenoid and temporal bone: A diagnostic dilemma. 61
30482404 2019
28
Endoscopic Endonasal Repair of a Persistent Craniopharyngeal Canal and Sphenoid Meningoencephalocele: Case Report and Review of Literature. 61
30391602 2019
29
[The application of cartilage in middle ear surgery]. 61
30550140 2018
30
Endoscopic management of paediatric meningoencephaloceles: a case series. 61
30218386 2018
31
Normative Data of the Interorbital Distance in Thai Population. 61
30234716 2018
32
Masses of developmental and genetic origin affecting the paediatric craniofacial skeleton. 61
29766474 2018
33
Orbital and nasal meningoencephaloceles secondary to chronic hydrocephalus: A rare cause of bilateral proptosis. 61
29882488 2018
34
Ethmoid Meningoencephalocele in a Patient with Cerebrofacial Arteriovenous Metameric Syndrome. 61
29510289 2018
35
Meningoencephalocele causing recurrent meningitis. 61
29744093 2018
36
Meningoencephalocele and Cerebrospinal Fluid Leak Complicating Orbital Decompression. 61
29342033 2018
37
Transcranial and Epidural Approach for Spontaneous Cerebrospinal Fluid Leakage Due to Meningoencephalocele of the Lateral Sphenoid Sinus. 61
29682061 2018
38
Multimaterial 3D printing preoperative planning for frontoethmoidal meningoencephalocele surgery. 61
29067504 2018
39
[Clinical experience of resection for nasal skull-base tumors by microsurgical-assisted technique]. 61
29737743 2018
40
Collagen matrix as an inlay in endoscopic skull base reconstruction. 61
28716164 2018
41
Transdural Propagation of Glioblastoma Through Foramen Rotundum. 61
29277589 2018
42
Frontoethmoidal meningoencephalocele: appraisal of a craniofacial surgical teaching program in Cambodia. 61
29192866 2018
43
Pediatric Meningoencephaloceles Endoscopic Endonasal Repair: Our Experience. 61
30288336 2018
44
[Experience of treating patients with lateral sphenoid sinus recess CSF leak]. 61
30721219 2018
45
55 Year-old Patient with Intranasal Mass. 61
29314773 2018
46
[Lateral extended transsphenoidal endoscopic approach through the pterygopalatine fossa in surgery for meningoencephalocele of the lateral sphenoid recess]. 61
30412162 2018
47
"Five-layer gasket seal" watertight closure for reconstruction of the skull base in complex bilateral traumatic intraorbital meningoencephaloceles: a case report and literature review. 61
29485295 2018
48
Orbital Meningoencephalocele and Pulsatile Proptosis: A Rare Entity. 61
29552427 2018
49
A novel fetal sequence patogenesis resulting in oral meningoencephalocele. 61
29749239 2018
50
Frontoethmoidal encephalocele presenting in concert with schizencephaly. 61
30603230 2018

Variations for Meningoencephalocele

Expression for Meningoencephalocele

Search GEO for disease gene expression data for Meningoencephalocele.

Pathways for Meningoencephalocele

GO Terms for Meningoencephalocele

Sources for Meningoencephalocele

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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