Meningoencephalocele disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: MNN022 MIFTS: 22	Meningoencephalocele Categories: Neuronal diseases, Rare diseases
Genes Tissues Related diseases Publications Expand all tables

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Aliases & Classifications for Meningoencephalocele

MalaCards integrated aliases for Meningoencephalocele:

Name: Meningoencephalocele ⁵³

Meningo-Encephalocele ⁷²

Encephalomeningocele ⁵³

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

UMLS ⁷² C3825985

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Summaries for Meningoencephalocele

NIH Rare Diseases : ⁵³ Meningoencephalocele is a type of encephalocele, which is an abnormal sac of fluid, brain tissue, and meninges (membranes that cover the brain and spinal cord) that extends through a defect in the skull. There are two main types of meningoencephalocele, which are named according to the location of the sac. The frontoethmoidal type is located at the frontal and ethmoid bones while the occipital type is located at the occipital bone. Hydrocephalus, abnormalities of the eyeball and tear duct, and other findings have been associated with the condition. Some affected individuals have intellectual or physical disabilities while others have normal development and abilities. The condition is typically congenital (present at birth) but has been reported to develop by chance in older individuals in rare cases. The underlying cause of the condition is uncertain, but environmental factors are thought to play a role. Treatment depends on the size, location and severity of the defect but mainly includes magnetic resonance imaging (MRI) to determine the severity of the defect, followed by surgery to repair it.

MalaCards based summary : Meningoencephalocele, also known as meningo-encephalocele, is related to podder-tolmie syndrome and meckel syndrome, type 2. An important gene associated with Meningoencephalocele is RMND5A (Required For Meiotic Nuclear Division 5 Homolog A). Affiliated tissues include brain, bone and spinal cord.

Wikipedia : ⁷⁵ Encephalocele, is a neural tube defect characterized by sac-like protrusions of the brain and the... more...

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Related Diseases for Meningoencephalocele

Diseases related to Meningoencephalocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 146)

#	Related Disease	Score
1	podder-tolmie syndrome	11.6
2	meckel syndrome, type 2	11.3
3	encephalocele	10.5
4	meningocele	10.5
5	meningitis	10.5
6	hydrocephalus	10.4
7	intracranial hypertension	10.4
8	congenital hydrocephalus	10.4
9	mollaret meningitis	10.4
10	cerebrospinal fluid leak	10.3
11	hypertelorism	10.3
12	exophthalmos	10.3
13	rare surgical neurologic disease	10.3
14	cleft palate, isolated	10.2
15	telecanthus	10.2
16	cleft lip	10.2
17	bacterial meningitis	10.2
18	neurofibromatosis, type iv, of riccardi	10.2
19	craniosynostosis	10.2
20	glioma	10.2
21	cleft lip/palate	10.2
22	glial tumor	10.2
23	frontal encephalocele	10.1
24	basal encephalocele	10.1
25	otitis media	10.1
26	neural tube defects	10.1
27	strabismus	10.1
28	ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus	10.1
29	temporal lobe epilepsy	10.1
30	mechanical strabismus	10.1
31	head injury	10.1
32	crouzon syndrome	10.0
33	frontonasal dysplasia 1	10.0
34	corpus callosum, agenesis of, with facial anomalies and cerebellar ataxia	10.0
35	ptosis	10.0
36	myelomeningocele	10.0
37	superior semicircular canal dehiscence	10.0
38	ventricular septal defect	10.0
39	heart septal defect	10.0
40	dermoid cyst	10.0
41	cystic teratoma	10.0
42	empty sella syndrome	10.0
43	rhinitis	10.0
44	holoprosencephaly	10.0
45	plexiform neurofibroma	10.0
46	pituitary gland disease	10.0
47	mature teratoma	10.0
48	eye disease	10.0
49	neurofibroma	10.0
50	microcephaly	10.0

Graphical network of the top 20 diseases related to Meningoencephalocele:

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Symptoms & Phenotypes for Meningoencephalocele

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Drugs & Therapeutics for Meningoencephalocele

Search Clinical Trials , NIH Clinical Center for Meningoencephalocele

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Genetic Tests for Meningoencephalocele

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Anatomical Context for Meningoencephalocele

MalaCards organs/tissues related to Meningoencephalocele:

⁴¹

Brain, Bone, Spinal Cord, Kidney, Eye, Pituitary, Skin

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Publications for Meningoencephalocele

Articles related to Meningoencephalocele:

(show top 50) (show all 472)

#	Title	Authors	PMID	Year
1	Incidental spontaneous CSF fistula with pterygoid process meningoencephalocele. ³⁸	Alhusain M...Aladwani N	31380824	2019
2	Nasal Framework Osteotomy: An Innovative Approach to Manage an Extremely Long Nose With Meningoencephalocele. ³⁸	Bohluli B...Abdolhoseinpour H	30851254	2019
3	Clinical, radiological features and surgical strategies for 23 NF1 patients with intraorbital meningoencephalocele. ³⁸	Niu J...Jia W	30868483	2019
4	Surgical Implications of the Anteriorly Displaced Segments of the Anterior Cerebral Artery in the Management of Frontoethmoidal Meningoencephalocele. ³⁸	Prasad V...Moore MH	31048610	2019
5	Endonasal endoscopic skullbase surgery in children. ³⁸	Deopujari CE...Mohanty CB	31079184	2019
6	Surgical correction of a meningoencephalocele in a thoroughbred filly. ³⁸	Buck AM...Hunt RJ	31135063	2019
7	Delayed presentation of morning glory disc anomaly and transsphenoidal encephalocele: A management dilemma. ³⁸	Koerner JC...Kenning TJ	31312233	2019
8	Surgical management of meningoencephalocele in temporal bone associated with pharmacoresistant epilepsy: report of two cases. ³⁸	Pejovic AT...Sokic D	29179608	2019
9	Giant meningoencephalocele with Arnold-Chiari type III malformation and anaesthetic challenges: A rare case report. ³⁸	Ganeriwal V...Gore B	31007660	2019
10	The reconstruction of skull base defects in infants using pedicled nasoseptal flap-a review of four cases. ³⁸	Shah N...Bommakanti V	30968177	2019
11	Outcome of Endoscopic Cerebrospinal Fluid Rhinorrhoea Repair: An Institutional Study. ³⁸	Majhi S...Sharma A	30906718	2019
12	Vascular malformation of the sphenoid and temporal bone: A diagnostic dilemma. ³⁸	Nagy CZ...Arturo Solares C	30482404	2019
13	Iatrogenic meningoencephalocele after traumatic perforation of the cribriform plate during nasal intubation of a preterm infant. ³⁸	Renaud M...Djennaoui I	30611097	2019
14	Temporal bone meningoencephaloceles and cerebrospinal fluid leaks: experience in a tertiary care hospital. ³⁸	Gupta A...Thakar A	30777139	2019
15	Endoscopic Endonasal Repair of a Persistent Craniopharyngeal Canal and Sphenoid Meningoencephalocele: Case Report and Review of Literature. ³⁸	Rajasekar G...Deepti A N	30391602	2019
16	[The application of cartilage in middle ear surgery]. ³⁸	Zhao YX...Yu LS	30550140	2018
17	Endoscopic management of paediatric meningoencephaloceles: a case series. ³⁸	Stavrakas M...Constantinidis J	30218386	2018
18	Normative Data of the Interorbital Distance in Thai Population. ³⁸	Chatdokmaiprai C...Taeshineetanakul P	30234716	2018
19	Masses of developmental and genetic origin affecting the paediatric craniofacial skeleton. ³⁸	Stefanelli S...Becker M	29766474	2018
20	Orbital and nasal meningoencephaloceles secondary to chronic hydrocephalus: A rare cause of bilateral proptosis. ³⁸	Jenner ZB...Esquenazi Y	29882488	2018
21	Dermoid cyst with cerebellar meningoencephalocele at different locations accompanied by posterior fossa abnormalities: case report. ³⁸	Tokmak TT...Gureli M	30156600	2018
22	Ethmoid Meningoencephalocele in a Patient with Cerebrofacial Arteriovenous Metameric Syndrome. ³⁸	Fernandez-Gajardo R...Zadeh G	29510289	2018
23	Meningoencephalocele and Cerebrospinal Fluid Leak Complicating Orbital Decompression. ³⁸	Cohen LM...Yoon MK	29342033	2018
24	Meningoencephalocele causing recurrent meningitis. ³⁸	Ruas R...Ribeiro N	29744093	2018
25	Transcranial and Epidural Approach for Spontaneous Cerebrospinal Fluid Leakage Due to Meningoencephalocele of the Lateral Sphenoid Sinus. ³⁸	Shintoku R...Yoshimoto Y	29682061	2018
26	Multimaterial 3D printing preoperative planning for frontoethmoidal meningoencephalocele surgery. ³⁸	Coelho G...Yoshida M	29067504	2018
27	[Clinical experience of resection for nasal skull-base tumors by microsurgical-assisted technique]. ³⁸	Zhu XJ...Chen ZB	29737743	2018
28	Collagen matrix as an inlay in endoscopic skull base reconstruction. ³⁸	Oakley GM...Harvey RJ	28716164	2018
29	Transdural Propagation of Glioblastoma Through Foramen Rotundum. ³⁸	Imataka S...Mikuni N	29277589	2018
30	Frontoethmoidal meningoencephalocele: appraisal of a craniofacial surgical teaching program in Cambodia. ³⁸	Roux FE...Lauwers F	29192866	2018
31	55 Year-old Patient with Intranasal Mass. ³⁸	Kennedy DW...Brody R	29314773	2018
32	Pediatric Meningoencephaloceles Endoscopic Endonasal Repair: Our Experience. ³⁸	Marfatia HK...Mishra S	30288336	2018
33	[Experience of treating patients with lateral sphenoid sinus recess CSF leak]. ³⁸	Shelesko EV...Tsukanova TV	30721219	2018
34	[Lateral extended transsphenoidal endoscopic approach through the pterygopalatine fossa in surgery for meningoencephalocele of the lateral sphenoid recess]. ³⁸	Sharipov OI...Kalinin PL	30412162	2018
35	A novel fetal sequence patogenesis resulting in oral meningoencephalocele. ³⁸	Gabor M...Ferianec V	29749239	2018
36	"Five-layer gasket seal" watertight closure for reconstruction of the skull base in complex bilateral traumatic intraorbital meningoencephaloceles: a case report and literature review. ³⁸	Zhao D...Wu A	29485295	2018
37	Orbital Meningoencephalocele and Pulsatile Proptosis: A Rare Entity. ³⁸	Umerani MS...Ghaziani MH	29552427	2018
38	Frontoethmoidal encephalocele presenting in concert with schizencephaly. ³⁸	Tanwir A...Shamim MS	30603230	2018
39	Acrania-exencephaly-anencephaly sequence phenotypic characterization using two- and three-dimensional ultrasound between 11 and 13 weeks and 6 days of gestation. ³⁸	Martins Santana EF...Meagher S	30451407	2018
40	Meningocele and Meningoencephalocele of the Lateral Wall of Sphenoidal Sinus. ³⁸	Zoli M...Pasquini E	29059790	2017
41	Safe and sustainable: the extracranial approach toward frontoethmoidal meningoencephalocele repair. ³⁸	Heidekrueger PI...Broer PN	28731403	2017
42	The First Reported Case of Meckel-Gruber Syndrome Associated With Abnormal Karyotype Mosaic Trisomy 17. ³⁸	Cierna Z...Szemes T	28812468	2017
43	True Transsphenoidal Meningoencephalocele. ³⁸	Das S...Collins T	28508543	2017
44	Fetal Pathology of Neural Tube Defects - An Overview of 68 Cases. ³⁸	Schoner K...Rehder H	28579621	2017
45	Coexistence of meningoencephalocele and hippocampal sclerosis: a new type of dual pathology. ³⁸	Martinoni M...Giulioni M	28353003	2017
46	Clinical Features, Imaging Characteristics, and Long-term Outcome of Dogs with Cranial Meningocele or Meningoencephalocele. ³⁸	Lazzerini K...Guevar J	28247440	2017
47	Excavating meningoencephaloceles: A newly recognized entity. ³⁸	Loftus PA...DelGaudio JM	28452710	2017
48	Surgery of Anterior Skull Base Lesions in Children. ³⁸	Hoffmann TK...Theodoraki MN	28092970	2017
49	Nontraumatic orbital roof encephalocele. ³⁸	Hoang A...Ikeda J	27993731	2017
50	[Endoscopic endonasal diagnosis and treatment of skull base meningoencephalocele]. ³⁸	Kapitanov DN...Danilov GV	28524124	2017

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Genes for Meningoencephalocele

Genes related to Meningoencephalocele (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	RMND5A	Required For Meiotic Nuclear Division 5 Homolog A	Protein Coding	6.87	GeneCards inferred via : Publications (show sections)

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Variations for Meningoencephalocele

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Expression for Meningoencephalocele

Search GEO for disease gene expression data for Meningoencephalocele.

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Pathways for Meningoencephalocele

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GO Terms for Meningoencephalocele

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