MCID: MNN022
MIFTS: 22

Meningoencephalocele

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Meningoencephalocele

MalaCards integrated aliases for Meningoencephalocele:

Name: Meningoencephalocele 53
Meningo-Encephalocele 72
Encephalomeningocele 53

Classifications:



External Ids:

UMLS 72 C3825985

Summaries for Meningoencephalocele

NIH Rare Diseases : 53 Meningoencephalocele is a type of encephalocele, which is an abnormal sac of fluid, brain tissue, and meninges (membranes that cover the brain and spinal cord) that extends through a defect in the skull. There are two main types of meningoencephalocele, which are named according to the location of the sac. The frontoethmoidal type is located at the frontal and ethmoid bones while the occipital type is located at the occipital bone. Hydrocephalus, abnormalities of the eyeball and tear duct, and other findings have been associated with the condition. Some affected individuals have intellectual or physical disabilities while others have normal development and abilities. The condition is typically congenital (present at birth) but has been reported to develop by chance in older individuals in rare cases. The underlying cause of the condition is uncertain, but environmental factors are thought to play a role. Treatment depends on the size, location and severity of the defect but mainly includes magnetic resonance imaging (MRI) to determine the severity of the defect, followed by surgery to repair it.

MalaCards based summary : Meningoencephalocele, also known as meningo-encephalocele, is related to podder-tolmie syndrome and meckel syndrome, type 2. An important gene associated with Meningoencephalocele is RMND5A (Required For Meiotic Nuclear Division 5 Homolog A). Affiliated tissues include brain, bone and spinal cord.

Wikipedia : 75 Encephalocele, is a neural tube defect characterized by sac-like protrusions of the brain and the... more...

Related Diseases for Meningoencephalocele

Diseases related to Meningoencephalocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 146)
# Related Disease Score Top Affiliating Genes
1 podder-tolmie syndrome 11.6
2 meckel syndrome, type 2 11.3
3 encephalocele 10.5
4 meningocele 10.5
5 meningitis 10.5
6 hydrocephalus 10.4
7 intracranial hypertension 10.4
8 congenital hydrocephalus 10.4
9 mollaret meningitis 10.4
10 cerebrospinal fluid leak 10.3
11 hypertelorism 10.3
12 exophthalmos 10.3
13 rare surgical neurologic disease 10.3
14 cleft palate, isolated 10.2
15 telecanthus 10.2
16 cleft lip 10.2
17 bacterial meningitis 10.2
18 neurofibromatosis, type iv, of riccardi 10.2
19 craniosynostosis 10.2
20 glioma 10.2
21 cleft lip/palate 10.2
22 glial tumor 10.2
23 frontal encephalocele 10.1
24 basal encephalocele 10.1
25 otitis media 10.1
26 neural tube defects 10.1
27 strabismus 10.1
28 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.1
29 temporal lobe epilepsy 10.1
30 mechanical strabismus 10.1
31 head injury 10.1
32 crouzon syndrome 10.0
33 frontonasal dysplasia 1 10.0
34 corpus callosum, agenesis of, with facial anomalies and cerebellar ataxia 10.0
35 ptosis 10.0
36 myelomeningocele 10.0
37 superior semicircular canal dehiscence 10.0
38 ventricular septal defect 10.0
39 heart septal defect 10.0
40 dermoid cyst 10.0
41 cystic teratoma 10.0
42 empty sella syndrome 10.0
43 rhinitis 10.0
44 holoprosencephaly 10.0
45 plexiform neurofibroma 10.0
46 pituitary gland disease 10.0
47 mature teratoma 10.0
48 eye disease 10.0
49 neurofibroma 10.0
50 microcephaly 10.0

Graphical network of the top 20 diseases related to Meningoencephalocele:



Diseases related to Meningoencephalocele

Symptoms & Phenotypes for Meningoencephalocele

Drugs & Therapeutics for Meningoencephalocele

Search Clinical Trials , NIH Clinical Center for Meningoencephalocele

Genetic Tests for Meningoencephalocele

Anatomical Context for Meningoencephalocele

MalaCards organs/tissues related to Meningoencephalocele:

41
Brain, Bone, Spinal Cord, Kidney, Eye, Pituitary, Skin

Publications for Meningoencephalocele

Articles related to Meningoencephalocele:

(show top 50) (show all 472)
# Title Authors PMID Year
1
Incidental spontaneous CSF fistula with pterygoid process meningoencephalocele. 38
31380824 2019
2
Nasal Framework Osteotomy: An Innovative Approach to Manage an Extremely Long Nose With Meningoencephalocele. 38
30851254 2019
3
Clinical, radiological features and surgical strategies for 23 NF1 patients with intraorbital meningoencephalocele. 38
30868483 2019
4
Surgical Implications of the Anteriorly Displaced Segments of the Anterior Cerebral Artery in the Management of Frontoethmoidal Meningoencephalocele. 38
31048610 2019
5
Endonasal endoscopic skullbase surgery in children. 38
31079184 2019
6
Surgical correction of a meningoencephalocele in a thoroughbred filly. 38
31135063 2019
7
Delayed presentation of morning glory disc anomaly and transsphenoidal encephalocele: A management dilemma. 38
31312233 2019
8
Surgical management of meningoencephalocele in temporal bone associated with pharmacoresistant epilepsy: report of two cases. 38
29179608 2019
9
Giant meningoencephalocele with Arnold-Chiari type III malformation and anaesthetic challenges: A rare case report. 38
31007660 2019
10
The reconstruction of skull base defects in infants using pedicled nasoseptal flap-a review of four cases. 38
30968177 2019
11
Outcome of Endoscopic Cerebrospinal Fluid Rhinorrhoea Repair: An Institutional Study. 38
30906718 2019
12
Vascular malformation of the sphenoid and temporal bone: A diagnostic dilemma. 38
30482404 2019
13
Iatrogenic meningoencephalocele after traumatic perforation of the cribriform plate during nasal intubation of a preterm infant. 38
30611097 2019
14
Temporal bone meningoencephaloceles and cerebrospinal fluid leaks: experience in a tertiary care hospital. 38
30777139 2019
15
Endoscopic Endonasal Repair of a Persistent Craniopharyngeal Canal and Sphenoid Meningoencephalocele: Case Report and Review of Literature. 38
30391602 2019
16
[The application of cartilage in middle ear surgery]. 38
30550140 2018
17
Endoscopic management of paediatric meningoencephaloceles: a case series. 38
30218386 2018
18
Normative Data of the Interorbital Distance in Thai Population. 38
30234716 2018
19
Masses of developmental and genetic origin affecting the paediatric craniofacial skeleton. 38
29766474 2018
20
Orbital and nasal meningoencephaloceles secondary to chronic hydrocephalus: A rare cause of bilateral proptosis. 38
29882488 2018
21
Dermoid cyst with cerebellar meningoencephalocele at different locations accompanied by posterior fossa abnormalities: case report. 38
30156600 2018
22
Ethmoid Meningoencephalocele in a Patient with Cerebrofacial Arteriovenous Metameric Syndrome. 38
29510289 2018
23
Meningoencephalocele and Cerebrospinal Fluid Leak Complicating Orbital Decompression. 38
29342033 2018
24
Meningoencephalocele causing recurrent meningitis. 38
29744093 2018
25
Transcranial and Epidural Approach for Spontaneous Cerebrospinal Fluid Leakage Due to Meningoencephalocele of the Lateral Sphenoid Sinus. 38
29682061 2018
26
Multimaterial 3D printing preoperative planning for frontoethmoidal meningoencephalocele surgery. 38
29067504 2018
27
[Clinical experience of resection for nasal skull-base tumors by microsurgical-assisted technique]. 38
29737743 2018
28
Collagen matrix as an inlay in endoscopic skull base reconstruction. 38
28716164 2018
29
Transdural Propagation of Glioblastoma Through Foramen Rotundum. 38
29277589 2018
30
Frontoethmoidal meningoencephalocele: appraisal of a craniofacial surgical teaching program in Cambodia. 38
29192866 2018
31
55 Year-old Patient with Intranasal Mass. 38
29314773 2018
32
Pediatric Meningoencephaloceles Endoscopic Endonasal Repair: Our Experience. 38
30288336 2018
33
[Experience of treating patients with lateral sphenoid sinus recess CSF leak]. 38
30721219 2018
34
[Lateral extended transsphenoidal endoscopic approach through the pterygopalatine fossa in surgery for meningoencephalocele of the lateral sphenoid recess]. 38
30412162 2018
35
A novel fetal sequence patogenesis resulting in oral meningoencephalocele. 38
29749239 2018
36
"Five-layer gasket seal" watertight closure for reconstruction of the skull base in complex bilateral traumatic intraorbital meningoencephaloceles: a case report and literature review. 38
29485295 2018
37
Orbital Meningoencephalocele and Pulsatile Proptosis: A Rare Entity. 38
29552427 2018
38
Frontoethmoidal encephalocele presenting in concert with schizencephaly. 38
30603230 2018
39
Acrania-exencephaly-anencephaly sequence phenotypic characterization using two- and three-dimensional ultrasound between 11 and 13 weeks and 6 days of gestation. 38
30451407 2018
40
Meningocele and Meningoencephalocele of the Lateral Wall of Sphenoidal Sinus. 38
29059790 2017
41
Safe and sustainable: the extracranial approach toward frontoethmoidal meningoencephalocele repair. 38
28731403 2017
42
The First Reported Case of Meckel-Gruber Syndrome Associated With Abnormal Karyotype Mosaic Trisomy 17. 38
28812468 2017
43
True Transsphenoidal Meningoencephalocele. 38
28508543 2017
44
Fetal Pathology of Neural Tube Defects - An Overview of 68 Cases. 38
28579621 2017
45
Coexistence of meningoencephalocele and hippocampal sclerosis: a new type of dual pathology. 38
28353003 2017
46
Clinical Features, Imaging Characteristics, and Long-term Outcome of Dogs with Cranial Meningocele or Meningoencephalocele. 38
28247440 2017
47
Excavating meningoencephaloceles: A newly recognized entity. 38
28452710 2017
48
Surgery of Anterior Skull Base Lesions in Children. 38
28092970 2017
49
Nontraumatic orbital roof encephalocele. 38
27993731 2017
50
[Endoscopic endonasal diagnosis and treatment of skull base meningoencephalocele]. 38
28524124 2017

Variations for Meningoencephalocele

Expression for Meningoencephalocele

Search GEO for disease gene expression data for Meningoencephalocele.

Pathways for Meningoencephalocele

GO Terms for Meningoencephalocele

Sources for Meningoencephalocele

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
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30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
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36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
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44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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