MENOQ1
MCID: MNP013
MIFTS: 12

Menopause, Natural, Age at, Quantitative Trait Locus 1 (MENOQ1)

Aliases & Classifications for Menopause, Natural, Age at, Quantitative Trait Locus 1

MalaCards integrated aliases for Menopause, Natural, Age at, Quantitative Trait Locus 1:

Name: Menopause, Natural, Age at, Quantitative Trait Locus 1 57
Menopause, Natural, Age at, Qtl 1 13
Menopause, Natural, Age at, Qtl1 57
Menoq1 57

Characteristics:

OMIM:

57
Inheritance:
x-linked dominant


HPO:

32
menopause, natural, age at, quantitative trait locus 1:
Inheritance x-linked dominant inheritance


External Ids:

OMIM 57 300488
MedGen 42 C1970897

Summaries for Menopause, Natural, Age at, Quantitative Trait Locus 1

MalaCards based summary : Menopause, Natural, Age at, Quantitative Trait Locus 1, also known as menopause, natural, age at, qtl 1, is related to premature ovarian failure 10. An important gene associated with Menopause, Natural, Age at, Quantitative Trait Locus 1 is MENOQ1 (Menopause, Natural, Age At, QTL). Affiliated tissues include heart, and related phenotype is abnormality of the endocrine system.

More information from OMIM: 300488

Related Diseases for Menopause, Natural, Age at, Quantitative Trait Locus 1

Diseases in the Menopause, Natural, Age at, Quantitative Trait Locus 1 family:

Menopause, Natural, Age at, Quantitative Trait Locus 2 Menopause, Natural, Age at, Quantitative Trait Locus 4

Diseases related to Menopause, Natural, Age at, Quantitative Trait Locus 1 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 premature ovarian failure 10 11.3

Symptoms & Phenotypes for Menopause, Natural, Age at, Quantitative Trait Locus 1

Human phenotypes related to Menopause, Natural, Age at, Quantitative Trait Locus 1:

32
# Description HPO Frequency HPO Source Accession
1 abnormality of the endocrine system 32 HP:0000818

Symptoms via clinical synopsis from OMIM:

57
Endocrine Features:
age at natural menopause qtl

Clinical features from OMIM:

300488

Drugs & Therapeutics for Menopause, Natural, Age at, Quantitative Trait Locus 1

Search Clinical Trials , NIH Clinical Center for Menopause, Natural, Age at, Quantitative Trait Locus 1

Genetic Tests for Menopause, Natural, Age at, Quantitative Trait Locus 1

Anatomical Context for Menopause, Natural, Age at, Quantitative Trait Locus 1

MalaCards organs/tissues related to Menopause, Natural, Age at, Quantitative Trait Locus 1:

41
Heart

Publications for Menopause, Natural, Age at, Quantitative Trait Locus 1

Articles related to Menopause, Natural, Age at, Quantitative Trait Locus 1:

# Title Authors PMID Year
1
Loci at chromosomes 13, 19 and 20 influence age at natural menopause. 8
19448619 2009
2
Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. 8
19448621 2009
3
Heritability of age at natural menopause in the Framingham Heart Study. 8
15769979 2005
4
Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative trait loci influencing variation in human menopausal age. 8
14872408 2004
5
The role of genetic factors in age at natural menopause. 8
11527915 2001
6
Estrogen receptor polymorphism predicts the onset of natural and surgical menopause. 8
10487678 1999
7
Genetic influences on the age at menopause. 8
9798581 1998
8
Genes control the cessation of a woman's reproductive life: a twin study of hysterectomy and age at menopause. 8
9626112 1998
9
Mothers and daughters menopausal ages: is there a link? 8
9243205 1997
10
Family history as a predictor of early menopause. 8
7672145 1995

Variations for Menopause, Natural, Age at, Quantitative Trait Locus 1

Expression for Menopause, Natural, Age at, Quantitative Trait Locus 1

Search GEO for disease gene expression data for Menopause, Natural, Age at, Quantitative Trait Locus 1.

Pathways for Menopause, Natural, Age at, Quantitative Trait Locus 1

GO Terms for Menopause, Natural, Age at, Quantitative Trait Locus 1

Sources for Menopause, Natural, Age at, Quantitative Trait Locus 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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