MCID: MNT259
MIFTS: 17

Mental Retardation, Obesity, Mandibular Prognathism, and Eye and Skin Anomalies

Categories: Endocrine diseases, Fetal diseases, Mental diseases, Metabolic diseases, Neuronal diseases, Rare diseases, Skin diseases

Aliases & Classifications for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

MalaCards integrated aliases for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and Skin Anomalies:

Name: Mental Retardation, Obesity, Mandibular Prognathism, and Eye and Skin Anomalies 58
Momes Syndrome 58 60 74
Intellectual Disability-Obesity-Prognathism-Eye and Skin Anomalies Syndrome 60

Characteristics:

Orphanet epidemiological data:

60
intellectual disability-obesity-prognathism-eye and skin anomalies syndrome
Inheritance: Autosomal dominant; Prevalence: <1/1000000 (Worldwide); Age of onset: Neonatal;

OMIM:

58
Inheritance:
autosomal recessive


HPO:

33
mental retardation, obesity, mandibular prognathism, and eye and skin anomalies:
Inheritance autosomal recessive inheritance


Classifications:



Summaries for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

MalaCards based summary : Mental Retardation, Obesity, Mandibular Prognathism, and Eye and Skin Anomalies, is also known as momes syndrome. Affiliated tissues include skin and eye, and related phenotypes are macrocephaly and obesity

Description from OMIM: 606772

Related Diseases for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

Symptoms & Phenotypes for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

Human phenotypes related to Mental Retardation, Obesity, Mandibular Prognathism, and Eye and Skin Anomalies:

33 (show all 17)
# Description HPO Frequency HPO Source Accession
1 macrocephaly 33 HP:0000256
2 obesity 33 HP:0001513
3 ptosis 33 HP:0000508
4 intellectual disability 33 HP:0001249
5 mandibular prognathia 33 HP:0000303
6 delayed speech and language development 33 HP:0000750
7 visual impairment 33 HP:0000505
8 cone-shaped epiphysis 33 HP:0010579
9 reduced visual acuity 33 HP:0007663
10 telecanthus 33 HP:0000506
11 dental crowding 33 HP:0000678
12 blepharophimosis 33 HP:0000581
13 hallux valgus 33 HP:0001822
14 esotropia 33 HP:0000565
15 atopic dermatitis 33 HP:0001047
16 abducens palsy 33 HP:0011349
17 hyperopic astigmatism 33 HP:0000484

Symptoms via clinical synopsis from OMIM:

58
Head And Neck Head:
macrocephaly

Head And Neck Eyes:
telecanthus
blepharophimosis
esotropia
abducens palsy
hyperopic astigmatism
more
Head And Neck Face:
prognathism

Skeletal Feet:
lateral deviation of halluces
cone-shaped epiphyses (toes 2,3, and 4)

Growth Weight:
obesity
birth weight >90th percentile

Head And Neck Teeth:
dental crowding

Neurologic Central Nervous System:
mental retardation
speech delay

Skin Nails Hair Skin:
atopic dermatitis, chronic

Clinical features from OMIM:

606772

Drugs & Therapeutics for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

Search Clinical Trials , NIH Clinical Center for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and Skin Anomalies

Genetic Tests for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

Anatomical Context for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

MalaCards organs/tissues related to Mental Retardation, Obesity, Mandibular Prognathism, and Eye and Skin Anomalies:

42
Skin, Eye

Publications for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

Variations for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

Expression for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

Search GEO for disease gene expression data for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and Skin Anomalies.

Pathways for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

GO Terms for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

Sources for Mental Retardation, Obesity, Mandibular Prognathism, and Eye and...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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