Aliases & Classifications for Mercury Poisoning

MalaCards integrated aliases for Mercury Poisoning:

Name: Mercury Poisoning 53 59
Mercury Intoxication 59
Mercury Toxicity 53
Mercurialism 59
Hydrargyria 59

Characteristics:

Orphanet epidemiological data:

59
mercury poisoning
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:



Summaries for Mercury Poisoning

NIH Rare Diseases : 53 Mercury poisoning is a condition that occurs in people who are exposed to toxic levels of the element, mercury. There are three different forms of mercury that can cause health problems:Elemental mercury (also known as liquid mercury or quicksilver) can be found in glass thermometers, electrical switches, dental fillings and fluorescent light bulbs. This form of mercury is generally only harmful when small droplets become airborne and are inhaled. If this occurs, signs and symptoms of poisoning may include metallic taste, vomiting, difficulty breathing, coughing, and/or swollen, bleeding gums. In severe cases, long-term brain damage, permanent lung damage and even death may occur. Inorganic mercury is found in batteries, chemistry labs, and some disinfectants. This form of mercury is harmful when swallowed. Signs and symptoms of inorganic mercury poisoning vary based on the amount consumed, but may include burning in the stomach and throat; vomiting; and/or bloody diarrhea. Inorganic mercury can also affect the kidneys and brain if it enters the blood stream. Organic mercury can be found in fish. Some organisms convert fumes from burning coal into organic mercury. This form of mercury is harmful if inhaled, eaten, or placed on the skin for long periods of time. Long-term exposure to organic mercury may result in skin numbness or pain; tremor; inability to walk well; blindness; double vision; memory problems; seizures; or even death. Treatment is generally supportive and based on the signs and symptoms present in each person. Medications called chelators, which remove mercury and heavy metals from the body, are generally prescribed.

MalaCards based summary : Mercury Poisoning, also known as mercury intoxication, is related to infantile mercury poisoning and erythromelalgia. An important gene associated with Mercury Poisoning is B2M (Beta-2-Microglobulin), and among its related pathways/superpathways are Allograft rejection and Formation of Fibrin Clot (Clotting Cascade). The drug Chelating Agents has been mentioned in the context of this disorder. Affiliated tissues include kidney, skin and brain, and related phenotypes are hypertension and seizures

Wikipedia : 76 Mercury poisoning is a type of metal poisoning due to mercury exposure. Symptoms depend upon the type,... more...

Related Diseases for Mercury Poisoning

Diseases in the Mercury Poisoning family:

Infantile Mercury Poisoning

Diseases related to Mercury Poisoning via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 infantile mercury poisoning 12.3
2 erythromelalgia 11.1
3 fetal methylmercury syndrome 10.4
4 omphalocele 10.2
5 pleural tuberculosis 10.1 B2M IL18
6 nephrotic syndrome 10.1
7 peritonitis 10.1
8 hepatitis 10.1
9 acute kidney failure 10.0 B2M IL18
10 latex allergy 10.0 IL13 IL18
11 eosinophilic gastritis 10.0 IL13 IL18
12 neuronitis 10.0
13 hepatitis b 10.0
14 autoinflammation, lipodystrophy, and dermatosis syndrome 9.9 IL13 IL18
15 visceral leishmaniasis 9.8 IL13 IL18
16 renal tubular acidosis 9.8
17 periostitis 9.8
18 thrombocytopenia 9.8
19 heavy metal poisoning 9.8
20 brucellosis 9.8
21 depression 9.8
22 myoclonus 9.8
23 toxic shock syndrome 9.8
24 thrombocytopenia due to platelet alloimmunization 9.8
25 fixed drug eruption 9.8
26 vaginitis 9.8
27 creutzfeldt-jakob disease 9.8
28 anuria 9.8
29 pheochromocytoma 9.8
30 movement disease 9.8
31 autism 9.8
32 hyperthyroidism 9.8
33 aging 9.8
34 myocardial infarction 9.8
35 pemphigus 9.8
36 pemphigus foliaceus 9.8
37 intracranial hypertension 9.8
38 hemophagocytic lymphohistiocytosis 9.8 B2M IL18
39 postaxial acrofacial dysostosis 9.8 PLAT THBD
40 eisenmenger syndrome 9.8 PLAT THBD
41 marantic endocarditis 9.8 PLAT THBD
42 dysfibrinogenemia 9.7 PLAT THBD
43 hepatic veno-occlusive disease 9.7 PLAT THBD
44 thrombophilia due to activated protein c resistance 9.7 PLAT THBD
45 thrombophilia due to thrombin defect 9.7 PLAT THBD
46 disseminated intravascular coagulation 9.7 PLAT THBD
47 antiphospholipid syndrome 9.7 PLAT THBD
48 allergic rhinitis 9.7 IL13 IL18
49 peripheral vascular disease 9.6 PLAT THBD
50 thrombosis 9.6 PLAT THBD

Graphical network of the top 20 diseases related to Mercury Poisoning:



Diseases related to Mercury Poisoning

Symptoms & Phenotypes for Mercury Poisoning

Human phenotypes related to Mercury Poisoning:

59 32 (show all 21)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 hypertension 59 32 frequent (33%) Frequent (79-30%) HP:0000822
2 seizures 59 32 frequent (33%) Frequent (79-30%) HP:0001250
3 confusion 59 32 frequent (33%) Frequent (79-30%) HP:0001289
4 dystonia 59 32 frequent (33%) Frequent (79-30%) HP:0001332
5 tremor 59 32 frequent (33%) Frequent (79-30%) HP:0001337
6 tachycardia 59 32 frequent (33%) Frequent (79-30%) HP:0001649
7 acute kidney injury 59 32 frequent (33%) Frequent (79-30%) HP:0001919
8 nausea 59 32 frequent (33%) Frequent (79-30%) HP:0002018
9 anorexia 59 32 frequent (33%) Frequent (79-30%) HP:0002039
10 respiratory distress 59 32 frequent (33%) Frequent (79-30%) HP:0002098
11 abnormality of the cerebral white matter 59 32 frequent (33%) Frequent (79-30%) HP:0002500
12 episodic vomiting 59 32 frequent (33%) Frequent (79-30%) HP:0002572
13 episodic abdominal pain 59 32 frequent (33%) Frequent (79-30%) HP:0002574
14 hypotension 59 32 frequent (33%) Frequent (79-30%) HP:0002615
15 respiratory failure 59 32 frequent (33%) Frequent (79-30%) HP:0002878
16 hypokalemia 59 32 frequent (33%) Frequent (79-30%) HP:0002900
17 generalized muscle weakness 59 32 frequent (33%) Frequent (79-30%) HP:0003324
18 interstitial pneumonitis 59 32 frequent (33%) Frequent (79-30%) HP:0006515
19 loss of consciousness 59 32 frequent (33%) Frequent (79-30%) HP:0007185
20 insomnia 59 32 frequent (33%) Frequent (79-30%) HP:0100785
21 dyspnea 59 Frequent (79-30%)

GenomeRNAi Phenotypes related to Mercury Poisoning according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Negative genetic interaction between PTTG1-/- and PTTG1+/+ GR00255-A-4 8.8 B2M IL13 THBD

MGI Mouse Phenotypes related to Mercury Poisoning:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.85 IL13 IL18 PLAT B2M THBD
2 digestive/alimentary MP:0005381 9.83 IL18 PLAT B2M THBD IL13
3 growth/size/body region MP:0005378 9.8 THBD IL13 IL18 PLAT B2M
4 hematopoietic system MP:0005397 9.77 IL18 PLAT B2M THBD IL13
5 homeostasis/metabolism MP:0005376 9.72 THBD IL13 IL18 PLAT B2M
6 immune system MP:0005387 9.65 IL13 IL18 PLAT B2M THBD
7 integument MP:0010771 9.55 IL18 PLAT B2M THBD IL13
8 mortality/aging MP:0010768 9.35 THBD IL13 IL18 PLAT B2M
9 reproductive system MP:0005389 8.92 THBD IL13 PLAT B2M

Drugs & Therapeutics for Mercury Poisoning

Drugs for Mercury Poisoning (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Chelating Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Pilot Proof of Concept Study of NBMI Treatment of Mercury Intoxication Completed NCT02486289 Phase 2 Emeramide;Placebo
2 Environmental Contaminants and Infant Development Completed NCT00013858

Search NIH Clinical Center for Mercury Poisoning

Genetic Tests for Mercury Poisoning

Anatomical Context for Mercury Poisoning

MalaCards organs/tissues related to Mercury Poisoning:

41
Kidney, Skin, Brain, Lung, Liver, Skeletal Muscle, Cortex

Publications for Mercury Poisoning

Articles related to Mercury Poisoning:

(show top 50) (show all 347)
# Title Authors Year
1
Fixed drug eruption due To 2,3-dimercapto-1-propanesulfonic acid (DMPS) treatment for mercury poisoning: a rare adverse effect. ( 29912651 )
2018
2
Mercury poisoning in a fisherman working on a pelagic fishing vessel due to excessive tuna consumption. ( 29093364 )
2018
3
Mercury Poisoning in a Toddler from Home Contamination due to Skin-Lightening Cream. ( 29395180 )
2018
4
The interwoven history of mercury poisoning in Ontario and Japan. ( 28385869 )
2017
5
An Enigmatic Case of Acute Mercury Poisoning: Clinical, Immunological Findings and Platelet Function. ( 29033890 )
2017
6
Mercury poisoning through intravenous administration: Two case reports with literature review. ( 29145289 )
2017
7
Assessment and management of elemental mercury poisoning-a case report. ( 28174636 )
2017
8
Cases of acute mercury poisoning by mercury vapor exposure during the demolition of a fluorescent lamp factory. ( 28649389 )
2017
9
MiR-92a and miR-486 are potential diagnostic biomarkers for mercury poisoning and jointly sustain NF-I_B activity in mercury toxicity. ( 29167424 )
2017
10
Mercury Poisoning at a Home Day Care Center - Hillsborough County, Florida, 2015. ( 28472024 )
2017
11
Mercury poisoning in the Grassy Narrows First Nation: history not completed. ( 28584045 )
2017
12
Acute mercury poisoning from occult ritual use. ( 28913479 )
2016
13
Mercury poisoning caused by Chinese folk prescription (CFP): A case report and analysis of both CFP and quackery. ( 27858849 )
2016
14
Occupational Metallic Mercury Poisoning in Gilders. ( 27112720 )
2016
15
Mercury Poisoning in Operational Settings among Gilders. ( 27651086 )
2016
16
The interwoven history of mercury poisoning in Ontario and Japan. ( 27920011 )
2016
17
Saint Ioannis Lampadistis, the first possible case of blindness due to organic mercury poisoning in history. ( 27686425 )
2016
18
Acute Mercury Poisoning in a Group of School Children. ( 27977534 )
2016
19
Notes from the Field: Acute Mercury Poisoning After Home Gold and Silver Smelting--Iowa, 2014. ( 26678598 )
2015
20
Mercury poisoning in two 13-year-old twin sisters. ( 26109979 )
2015
21
Mercury poisoning presenting as sporadic creutzfeldt-jakob disease: a case report. ( 25775335 )
2015
22
Current approaches of the management of mercury poisoning: need of the hour. ( 24888360 )
2014
23
Mercury Poisoning as a Cause of Intracranial Hypertension. ( 25122110 )
2014
24
Subacute motor neuron hyperexcitability with mercury poisoning: a case series and literature review. ( 25227723 )
2014
25
Mercury poisoning: a case of a complex neuropsychiatric illness. ( 25756767 )
2014
26
Acute mercury poisoning presenting as fever of unknown origin in an adult woman: a case report. ( 25084829 )
2014
27
Mercury poisoning dentistry: high-level indoor air mercury contamination at selected dental sites. ( 24552960 )
2014
28
Ophthalmic findings in acute mercury poisoning in adults: A case series study. ( 23524881 )
2013
29
Mercury poisoning from home gold amalgam extraction. ( 23879513 )
2013
30
Acute mercury poisoning among children in two provinces of Turkey. ( 23411638 )
2013
31
The role of chelation in the treatment of arsenic and mercury poisoning. ( 24178900 )
2013
32
Public health department response to mercury poisoning: the importance of biomarkers and risks and benefits analysis for chelation therapy. ( 24197663 )
2013
33
Not all that glitters: mercury poisoning in Colombia. ( 22509527 )
2012
34
Elemental mercury poisoning presenting as hypertension in a young child. ( 22863825 )
2012
35
Chronic methyl mercury poisoning may trigger endemic pemphigus foliaceus "fogo selvagem". ( 22000710 )
2012
36
Mercury poisoning: a diagnostic challenge. ( 23128656 )
2012
37
Assessment and management of mercury poisoning with an unusual abdominal x-ray! ( 23087291 )
2012
38
Metal mercury poisoning in two boys initially treated for brucellosis in Mashhad, Iran. ( 21803782 )
2012
39
Pediatric mercury poisoning, brain MRI, and white matter hyperintensities. ( 21340488 )
2011
40
Inorganic mercury poisoning associated with skin-lightening cosmetic products. ( 22070559 )
2011
41
Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning. ( 20810785 )
2011
42
Re: Care of patients who are worried about mercury poisoning from dental fillings. ( 21737774 )
2011
43
Elemental mercury poisoning caused by subcutaneous and intravenous injection: An unusual self-injury. ( 20607031 )
2010
44
Fatal mercury poisoning and chelating agents. ( 20537473 )
2010
45
Acute mercury poisoning: a case report. ( 20302609 )
2010
46
Mercury poisoning in a free-living northern river otter (Lontra canadensis). ( 20688719 )
2010
47
Chronic mercury poisoning: Report of two siblings. ( 20808663 )
2010
48
Images in radiology. An element of surprise. Mercury poisoning. ( 20920692 )
2010
49
Care of patients who are worried about mercury poisoning from dental fillings. ( 21057078 )
2010
50
Mercury poisoning: a rare but treatable cause of failure to thrive and developmental regression in an infant. ( 19197099 )
2009

Variations for Mercury Poisoning

Expression for Mercury Poisoning

Search GEO for disease gene expression data for Mercury Poisoning.

Pathways for Mercury Poisoning

GO Terms for Mercury Poisoning

Cellular components related to Mercury Poisoning according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.46 B2M IL13 IL18 PLAT
2 cell surface GO:0009986 9.13 B2M PLAT THBD
3 extracellular space GO:0005615 9.02 B2M IL13 IL18 PLAT THBD

Biological processes related to Mercury Poisoning according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.33 B2M IL13 IL18
2 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 8.96 IL13 IL18
3 positive regulation of smooth muscle cell proliferation GO:0048661 8.62 IL13 IL18

Sources for Mercury Poisoning

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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