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MCID: MSN002
MIFTS: 35

Mesenteric Lymphadenitis

Categories: Immune diseases
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Aliases & Classifications for Mesenteric Lymphadenitis

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MalaCards integrated aliases for Mesenteric Lymphadenitis:

Name: Mesenteric Lymphadenitis 11 43 14 71 75
Mesenteric Adenitis 11

Classifications:

MalaCards categories:
Anatomical: Immune diseases
See all MalaCards categories (disease lists)
ICD10: 31


External Ids:

Disease Ontology 11 DOID:10782
ICD9CM 34 289.2
MeSH 43 D008640
NCIt 49 C26830
SNOMED-CT 68 191376006
ICD10 31 I88.0
UMLS 71 C0025469
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Summaries for Mesenteric Lymphadenitis

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MalaCards based summary: Mesenteric Lymphadenitis, also known as mesenteric adenitis, is related to lymphadenitis and intussusception. An important gene associated with Mesenteric Lymphadenitis is CRP (C-Reactive Protein), and among its related pathways/superpathways are Neuroinflammation and glutamatergic signaling and Spinal cord injury. Affiliated tissues include lymph node, appendix and small intestine, and related phenotype is cardiovascular system.
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Related Diseases for Mesenteric Lymphadenitis

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Diseases related to Mesenteric Lymphadenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 809)
# Related Disease Score Top Affiliating Genes
1 lymphadenitis 31.2 TNF IL6 IL1B CRP
2 intussusception 30.4 IL6 CRP ALB
3 tuberculous peritonitis 30.3 CRP ALB
4 appendicitis 30.3 TNF IL6 IL1B CRP ALB
5 whipple disease 30.2 TNF CRP ALB
6 cholecystitis 30.2 GPT CRP ALB
7 ascaris lumbricoides infection 30.1 GPT ALB
8 portal vein thrombosis 30.1 GPT CRP ALB
9 active peptic ulcer disease 30.1 GPT CRP ALB
10 diabetes mellitus, ketosis-prone 29.9 GPT CRP ALB ACE2
11 gallbladder disease 29.8 IL6 GPT CRP ALB
12 peritonitis 29.7 TNF IL6 IL1B CRP ALB
13 toxoplasmosis 29.7 TNF IL6 IL1B
14 beta-thalassemia 29.7 NPPB IL6 GPT CRP
15 granulomatous hepatitis 29.7 TNF GPT CRP ALB
16 abdominal tuberculosis 29.7 TNF GPT CRP ALB
17 ileus 29.6 TNF IL6 IL1B CRP
18 erythema nodosum 29.6 TNF IL6 IL1B CRP
19 intestinal obstruction 29.6 TNF IL6 GPT CRP ALB
20 listeriosis 29.5 TNF IL6 IL1B
21 inflammatory bowel disease 1 29.5 TNF IL6 IL1B
22 salmonellosis 29.5 TNF IL6 IL1B
23 colitis 29.4 TNF IL6 IL1B CRP
24 crohn's disease 29.4 TNF IL6 IL1B CRP ALB
25 acquired immunodeficiency syndrome 29.4 TNF IL6 IL1B CRP ALB
26 ulcerative colitis 29.3 TNF IL6 IL1B CRP
27 pharyngitis 29.3 TNF IL6 IL1B GPT CRP
28 sarcoidosis 1 29.2 TNF IL6 IL1B CRP ALB
29 pulmonary tuberculosis 29.2 TNF IL6 IL1B CRP ALB
30 gastroenteritis 29.2 TNF IL6 IL1B CRP ALB
31 glomerulonephritis 29.2 TNF IL6 IL1B CRP ALB
32 immune deficiency disease 29.1 TNF IL6 IL1B GPT CRP ACE2
33 diarrhea 29.0 TNF IL6 IL1B GPT ALB
34 plague 29.0 TNF IL6 IL1B ARPP21 ALB ACE2
35 septic arthritis 28.9 TNF IL6 IL1B GPT CRP ALB
36 covid-19 28.9 TNF NPPB IL6 IL1B CRP ACE2
37 peptic ulcer disease 28.9 TNF IL6 IL1B GPT CRP ALB
38 typhoid fever 28.9 TNF IL6 IL1B GPT CRP ALB
39 bowel dysfunction 28.9 TNF IL6 IL1B GPT CRP ALB
40 otitis media 28.9 TNF IL6 IL1B GPT CRP ALB
41 thrombocytopenia 28.8 TNF IL6 IL1B GPT CRP ALB
42 malaria 28.7 TNF IL6 IL1B GPT CRP ALB
43 inflammatory bowel disease 28.6 TNF ITGAE IL6 IL1B CRP ALB
44 bronchopneumonia 28.5 VAPA TNF IL6 IL1B GPT CRP
45 celiac disease 1 28.4 TNF ITGAE IL6 IL1B GPT CRP
46 cavernous sinus thrombosis 10.3 CRP ACE2
47 chronic duodenal ileus 10.3 CRP ALB
48 intracranial sinus thrombosis 10.3 CRP ACE2
49 acute necrotizing encephalitis 10.3 IL6 ACE2
50 ankylosing spondylitis 3 10.3 CRP ALB

Graphical network of the top 20 diseases related to Mesenteric Lymphadenitis:



Diseases related to Mesenteric Lymphadenitis
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Symptoms & Phenotypes for Mesenteric Lymphadenitis

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MGI Mouse Phenotypes related to Mesenteric Lymphadenitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.28 ACE2 ALB ANGPTL4 CRP IL1B IL6
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Drugs & Therapeutics for Mesenteric Lymphadenitis

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Search Clinical Trials, NIH Clinical Center for Mesenteric Lymphadenitis

Cochrane evidence based reviews: mesenteric lymphadenitis

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Genetic Tests for Mesenteric Lymphadenitis

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Anatomical Context for Mesenteric Lymphadenitis

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Organs/tissues related to Mesenteric Lymphadenitis:

MalaCards : Lymph Node, Appendix, Small Intestine, Liver, Spleen, Neutrophil, Cortex
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Publications for Mesenteric Lymphadenitis

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Articles related to Mesenteric Lymphadenitis:

(show top 50) (show all 597)
# Title Authors PMID Year
1
Intussusception and COVID-19 in Children: A Systematic Review and Meta-Analysis. 62
36421194 2022
2
Ventricular septal defect with recurrent abdominal pain misdiagnosed as mesenteric lymphadenitis: A case report. 62
35589477 2022
3
Study on the mechanism of Ginseng-Gegen for mesenteric lymphadenitis based on network pharmacology. 62
36247894 2022
4
Chronic Leptin Deficiency Improves Tolerance of Physiological Damage and Host-Pathogen Cooperation during Yersinia pseudotuberculosis Infection. 62
35924898 2022
5
An Atypical Presentation of Crohn's Disease: A Case Report. 62
36299929 2022
6
Ileocolic Thrombophlebitis and Lymphadenitis Mimicking Acute Appendicitis as a Late Manifestation in a COVID-19 Patient: A Case Report. 62
36249632 2022
7
First Description of a Yersinia pseudotuberculosis Clonal Outbreak in France, Confirmed Using a New Core Genome Multilocus Sequence Typing Method. 62
35863020 2022
8
Nerve Identification Procedures Are Necessary for Complete Recovery From Recurrent Cases of Anterior Cutaneous Nerve Entrapment Syndrome: A Case Report. 62
35923491 2022
9
Extensively Drug-Resistant Salmonella typhi Infection: From Pill to Scalpel. 62
35832758 2022
10
Value of high frequency ultrasonography in differential diagnosis of mesenteric lymphadenitis and acute appendicitis in children. 62
35084151 2022
11
Mesenteric Lymphadenitis Presenting as Acute Abdomen in a Child with Multisystem Inflammatory Syndrome. 62
35735756 2022
12
Molecular detection, biotyping and serotyping of Yersinia enterocolitica isolated from chicken livers in Tabriz. 62
35228160 2022
13
Acute abdomen in multisystem inflammatory syndrome in children: A systematic review. 62
34751972 2022
14
Mesenteric Lymphadenitis and Terminal Ileitis is Associated With Yersinia Infection: A Meta-analysis. 62
34628159 2022
15
Emergency diagnostic laparoscopy for multisystem inflammatory syndrome in a child. 62
35004171 2022
16
Chilaiditi syndrome in a Nepalese girl - A potential mislead! 62
35151159 2022
17
A Rare Case of Typhoid Fever in the United States Associated With Travel to Mexico. 62
35350527 2022
18
[Far East scarlet-like fever in a Caucasian man with Yersinia pseudotuberculosis bacteriaemia]. 62
34983723 2022
19
COVID-19-Related Intestinal Ischemia in A 7-Year Old Boy. 62
35992308 2022
20
Abdominal pain in children with COVID-19. 62
36223151 2022
21
Efficacy of Prednisone in Children with Acute Nonspecific Mesenteric Lymphadenitis: A Pilot Study. 62
35793505 2022
22
Clinical Value of Abdominal Ultrasonography in the Diagnosis of Acute Abdomen in Children. 62
35833064 2022
23
Role of the Yersinia pseudotuberculosis Virulence Plasmid in Pathogen-Phagocyte Interactions in Mesenteric Lymph Nodes. 62
34910573 2021
24
Homozygous MEFV Gene Variant and Pyrin-Associated Autoinflammation With Neutrophilic Dermatosis: A Family With a Novel Autosomal Recessive Mode of Inheritance. 62
34643647 2021
25
[Upper gastrointestinal bleeding due to tuberculous mesenteric lymphadenitis that fistulizes the gastric wall]. 62
35613400 2021
26
Liver Involvement in Children with COVID-19 and Multisystem Inflammatory Syndrome: A Single-Center Bulgarian Observational Study. 62
34576853 2021
27
Severe acute liver injury associated with Yersinia enterocolitica. 62
34230045 2021
28
Mesenteric Lymphadenitis Due to COVID-19 in an Adult. 62
34336415 2021
29
Testicular Pain and Mesenteric Adenitis as an Atypical Presentation of COVID-19. 62
34211816 2021
30
Evidence for the medicinal value of Squama Manitis (pangolin scale): A systematic review. 62
32837905 2021
31
Serological investigation and genotyping of Mycobacterium avium subsp. paratuberculosis in sheep and goats in Inner Mongolia, China. 62
34492040 2021
32
Histiocytic Necrotizing Lymphadenitis Mimicking Acute Appendicitis in a Child: A Case Report. 62
34604132 2021
33
Childhood Mesenteric Adenitis -The Spectrum of Findings. 62
34812157 2021
34
Atypical and novel presentations of Coronavirus Disease 2019: a case series of three children. 62
32552415 2021
35
Incidental unilateral idiopathic maculopathy in children. 62
33248251 2020
36
Prevalence of Rotaviruses in the Etiology of Acute Diarrhea in Young Children, Clinical forms, Extraintestinal Manifestations and Complications. 62
33500370 2020
37
Paediatric abdominal pain in the time of COVID-19: a new diagnostic dilemma. 62
32994918 2020
38
Acute lameness in a cat with disseminated mycobacteriosis. 62
33543916 2020
39
Unilateral inguinal lymphadenitis caused by Yersinia pseudotuberculosis. A case report. 62
32386928 2020
40
Far Eastern Scarlet-Like Fever is a Special Clinical and Epidemic Manifestation of Yersinia pseudotuberculosis Infection in Russia. 62
32498317 2020
41
Salmonella Mesenteric Lymphadenitis Causing Septic Peritonitis in Two Dogs. 62
32161715 2020
42
Acute mesenteric lymphadenitis in children: findings related to differential diagnosis and hospitalization. 62
32190142 2020
43
[CME Sonography 91: Differential Diagnosis of Lower Abdominal Pain]. 62
32517594 2020
44
Reference intervals of mesenteric lymph node size according to lymphocyte counts in asymptomatic children. 62
32040486 2020
45
Characteristics and Epidemiological Investigation of Paratuberculosis in Dairy Cattle in Tai'an, China. 62
32258119 2020
46
A comprehensive review on the prevalence, pathogenesis and detection of Yersinia enterocolitica. 62
35540058 2019
47
Acute fulminant necrotizing mesenteric lymphadenitis causing bowel ischemia. 62
31723403 2019
48
Yersinia Phages and Food Safety. 62
31795231 2019
49
Selection of Pneumatic Reduction in Invagination Treatment and the Factors Affecting the Success of This Method. 62
31788385 2019
50
Ulcerative, granulomatous glossitis and enteritis caused by Rhodococcus equi in a heifer. 62
31347467 2019
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Variations for Mesenteric Lymphadenitis

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Expression for Mesenteric Lymphadenitis

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Search GEO for disease gene expression data for Mesenteric Lymphadenitis.
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Pathways for Mesenteric Lymphadenitis

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Pathways related to Mesenteric Lymphadenitis according to GeneCards Suite gene sharing:

(show all 26)
# Super pathways Score Top Affiliating Genes
1
Neuroinflammation and glutamatergic signaling 74
11.95 TNF IL6 IL1B
2
Spinal cord injury 74
11.84 TNF IL6 IL1B
3
Interleukin-4 and Interleukin-13 signaling 66
11.81 TNF IL6 IL1B
4
IL27-mediated signaling events 61
Show member pathways
 11.76 TNF IL6 IL1B
5
Innate Lymphoid Cells Differentiation 65
11.65 TNF ITGAE IL1B
6
Network map of SARS-CoV-2 signaling pathway 74
Show member pathways
 11.62 IL6 CRP ACE2
7
Burn wound healing 74
11.6 TNF IL6 IL1B
8
Extrafollicular B cell activation by SARS-CoV-2 74
11.56 TNF IL6 CRP
9
Lung fibrosis 74
11.5 IL1B IL6 TNF
10
Photodynamic therapy-induced NF-kB survival signaling 74
Show member pathways
 11.49 IL1B IL6 TNF
11
IL 10 signaling pathway 67
11.46 TNF IL6 IL1B
12
Interleukin-10 signaling 66
11.3 TNF IL6 IL1B
13
Transcription_Role of VDR in regulation of genes involved in osteoporosis 22
11.26 TNF IL6 IL1B
14
Dendritic Cells Developmental Lineage Pathway 65
11.13 TNF ITGAE IL6 IL1B
15
IL-10 Pathway 64
11.12 TNF IL6 IL1B
16
Development and heterogeneity of the ILC family 74
11.05 TNF IL6 IL1B
17
Cytokines and inflammatory response 74
10.96 TNF IL6 IL1B
18
Cellular roles of Anthrax toxin 61
10.9 TNF IL1B
19
Prostaglandin signaling 74
10.88 TNF IL6 IL1B
20
NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence 74
10.85 IL6 IL1B
21
LDL Oxidation in Atherogenesis 64
10.82 TNF IL1B
22
IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types 65
10.67 IL6 IL1B
23
Overview of nanoparticle effects 74
10.61 TNF IL6 CRP
24
COVID-19 adverse outcome pathway 74
10.58 IL6 ACE2
25
Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway 74
10.4 TNF IL6 IL1B ACE2
26
Cells and molecules involved in local acute inflammatory response 74
Show member pathways
 10.18 TNF IL6
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GO Terms for Mesenteric Lymphadenitis

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Cellular components related to Mesenteric Lymphadenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 TNF NPPB IL6 IL1B GPT CRP

Biological processes related to Mesenteric Lymphadenitis according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 defense response to Gram-positive bacterium GO:0050830 10.01 CRP IL1B IL6 TNF
2 positive regulation of interleukin-8 production GO:0032757 10 TNF IL6 IL1B
3 regulation of insulin secretion GO:0050796 9.99 TNF IL6 IL1B
4 positive regulation of chemokine production GO:0032722 9.88 TNF IL6 IL1B
5 regulation of establishment of endothelial barrier GO:1903140 9.85 TNF IL1B
6 positive regulation of fever generation GO:0031622 9.8 TNF IL1B
7 negative regulation of neurogenesis GO:0050768 9.8 TNF IL6 IL1B
8 COPII-coated vesicle budding GO:0090114 9.76 VAPB VAPA
9 sequestering of triglyceride GO:0030730 9.73 TNF IL1B
10 positive regulation of glial cell proliferation GO:0060252 9.73 TNF IL6 IL1B
11 negative regulation by host of viral genome replication GO:0044828 9.71 VAPB VAPA
12 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.67 TNF IL1B
13 positive regulation of neuroinflammatory response GO:0150078 9.63 TNF IL6 IL1B
14 negative regulation of lipid storage GO:0010888 9.43 TNF IL6 CRP
15 vascular endothelial growth factor production GO:0010573 9.1 TNF IL6 IL1B

Molecular functions related to Mesenteric Lymphadenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 FFAT motif binding GO:0033149 8.92 VAPB VAPA
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Sources for Mesenteric Lymphadenitis

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2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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