MCID: MSN003
MIFTS: 35

Mesenteric Vascular Occlusion

Categories: Cardiovascular diseases

Aliases & Classifications for Mesenteric Vascular Occlusion

MalaCards integrated aliases for Mesenteric Vascular Occlusion:

Name: Mesenteric Vascular Occlusion 12 45 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:13252
MeSH 45 D008641
UMLS 74 C0025472

Summaries for Mesenteric Vascular Occlusion

MalaCards based summary : Mesenteric Vascular Occlusion is related to spinal cord infarction and thrombophlebitis. An important gene associated with Mesenteric Vascular Occlusion is FGF10 (Fibroblast Growth Factor 10), and among its related pathways/superpathways are Selenium Micronutrient Network and Warfarin Pathway, Pharmacodynamics. The drugs Dalteparin and Heparin have been mentioned in the context of this disorder. Affiliated tissues include colon, spinal cord and small intestine, and related phenotypes are growth/size/body region and embryo

Related Diseases for Mesenteric Vascular Occlusion

Diseases related to Mesenteric Vascular Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 74)
# Related Disease Score Top Affiliating Genes
1 spinal cord infarction 29.6 F2 MTHFR
2 thrombophlebitis 29.6 F2 MTHFR
3 thrombophilia due to thrombin defect 29.4 F2 MTHFR
4 thrombosis 29.2 F2 F7 MTHFR
5 pleuropulmonary blastoma 10.2 FGF10 MB
6 visual agnosia 10.1 F7 MB
7 cervical intraepithelial neoplasia 10.0 MTHFR ODC1
8 ischemic heart disease 10.0 F7 MTHFR
9 intestinal obstruction 10.0
10 colorectal adenoma 10.0 MTHFR ODC1
11 subendocardial myocardial infarction 10.0 F2 MB
12 compartment syndrome 10.0 F2 MB
13 carotid stenosis 10.0 F7 MTHFR
14 prothrombin deficiency 9.9 F2 F7
15 anterior cranial fossa meningioma 9.9 F2 F7
16 inherited blood coagulation disease 9.9 F2 F7
17 intestinal benign neoplasm 9.9 LGR5 MTHFR ODC1
18 hemophilia 9.9 F2 F7
19 sudden sensorineural hearing loss 9.9 F2 MTHFR
20 cavernous hemangioma 9.9 F2 MB
21 ischemic neuropathy 9.9 F2 MTHFR
22 cryptogenic cirrhosis 9.9 F2 MTHFR
23 porencephaly 9.9 F2 MTHFR
24 factor vii deficiency 9.9 F2 F7
25 marantic endocarditis 9.9 F2 MTHFR
26 hemophilia b 9.9 F2 F7
27 livedoid vasculitis 9.9 F2 MTHFR
28 hepatic infarction 9.9 F2 MTHFR
29 retinal vascular occlusion 9.9 F2 MTHFR
30 antithrombin iii deficiency 9.9 F2 MTHFR
31 colonic atresia 9.9
32 pain agnosia 9.9
33 inguinal hernia 9.9
34 mumps 9.9
35 macroglobulinemia 9.9
36 buerger disease 9.9 F2 MTHFR
37 central retinal vein occlusion 9.9 F2 MTHFR
38 retinal vein occlusion 9.9 F2 MTHFR
39 factor x deficiency 9.9 F2 F7
40 large intestine cancer 9.9 LGR5 MTHFR ODC1
41 blood protein disease 9.9 F2 MTHFR
42 branch retinal artery occlusion 9.9 F2 MTHFR
43 retinal artery occlusion 9.9 F2 MTHFR
44 hepatic vascular disease 9.8 F2 MTHFR
45 pulmonary artery disease 9.8 F2 MTHFR
46 arteritic anterior ischemic optic neuropathy 9.8 F2 MTHFR
47 factor v deficiency 9.8 F2 F7
48 ischemic optic neuropathy 9.8 F2 MTHFR
49 protein s deficiency 9.8 F2 MTHFR
50 placental abruption 9.8 F2 MTHFR

Graphical network of the top 20 diseases related to Mesenteric Vascular Occlusion:



Diseases related to Mesenteric Vascular Occlusion

Symptoms & Phenotypes for Mesenteric Vascular Occlusion

MGI Mouse Phenotypes related to Mesenteric Vascular Occlusion:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.8 F2 F7 FGF10 LGR5 MB MTHFR
2 embryo MP:0005380 9.72 F2 FGF10 HOPX MB ODC1
3 homeostasis/metabolism MP:0005376 9.7 F2 F7 FGF10 HOPX LGR5 MB
4 mortality/aging MP:0010768 9.56 F2 F7 FGF10 HOPX LGR5 MB
5 respiratory system MP:0005388 9.02 F2 FGF10 HOPX LGR5 MB

Drugs & Therapeutics for Mesenteric Vascular Occlusion

Drugs for Mesenteric Vascular Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 23)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dalteparin Approved Phase 4 9005-49-6
2
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
3
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
4 Anticoagulants Phase 4
5 Calcium, Dietary Phase 4
6 Fibrinolytic Agents Phase 4
7 calcium heparin Phase 4
8 Heparin, Low-Molecular-Weight Phase 4
9 Menaquinone Approved, Investigational 1182-68-9
10
Phylloquinone Approved, Investigational 84-80-0
11
Protein C Approved
12
Menadione Approved, Nutraceutical 58-27-5 4055
13 Kava Approved, Investigational, Nutraceutical 9000-38-8
14
Serine Approved, Nutraceutical 56-45-1 5951
15 Antithrombins
16 naphthoquinone
17
protease inhibitors
18 Vitamins
19 protein S
20 Antithrombin III
21 Vitamin K
22 HIV Protease Inhibitors
23 Serine Proteinase Inhibitors

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Predictive Factors of Intestinal Infraction in Acute Mesenteric Ischemia Completed NCT02645240 Phase 4 Heparin injection
2 Risk Factors and Outcomes of Acute Venous Thromboembolism in Cirrhotic Not yet recruiting NCT03580577

Search NIH Clinical Center for Mesenteric Vascular Occlusion

Cochrane evidence based reviews: mesenteric vascular occlusion

Genetic Tests for Mesenteric Vascular Occlusion

Anatomical Context for Mesenteric Vascular Occlusion

MalaCards organs/tissues related to Mesenteric Vascular Occlusion:

42
Colon, Spinal Cord, Small Intestine, Heart

Publications for Mesenteric Vascular Occlusion

Articles related to Mesenteric Vascular Occlusion:

(show top 50) (show all 117)
# Title Authors Year
1
Rectus sheath block for postoperative analgesia in patients with mesenteric vascular occlusion undergoing laparotomy: A randomized single-blinded study. ( 27746544 )
2016
2
Mesenteric vascular occlusion: comparison of ancillary CT findings between arterial and venous occlusions and independent CT findings suggesting life-threatening events. ( 23323029 )
2013
3
Intestinal gangrene due to mesenteric vascular occlusion masquerading as strangulated inguinal hernia. ( 17687510 )
2008
4
Management of mesenteric vascular occlusion. ( 18418524 )
2008
5
Spinal cord infarction following surgery for mesenteric vascular occlusion. ( 18046296 )
2007
6
Colonic atresia without mesenteric vascular occlusion. The role of the fibroblast growth factor 10 signaling pathway. ( 15750935 )
2005
7
Effect of prolonged selective intramesenteric arterial vasodilator therapy on intestinal viability after acute segmental mesenteric vascular occlusion. ( 11420490 )
2001
8
Mesenteric vascular occlusion resulting in intestinal necrosis in children. ( 10945686 )
2000
9
Acute mesenteric vascular occlusion: analysis of 39 patients. ( 9562280 )
1998
10
Laser Doppler flowmetry in experimental mesenteric vascular occlusion. ( 2659544 )
1989
11
Mesenteric vascular occlusion: a new diagnostic method using a radiolabeled monoclonal antibody reactive with platelets. ( 2717735 )
1989
12
Use of trans-serosal PO2 to determine intestinal viability in acute mesenteric vascular occlusion. ( 3595206 )
1987
13
Problems in acute mesenteric vascular occlusion. ( 3731831 )
1986
14
Acute superior mesenteric vascular occlusion following internal herniation of redundant sigmoid colon. ( 3830400 )
1985
15
Phaeochromocytoma presenting as a case of mesenteric vascular occlusion. ( 4086256 )
1985
16
Survival after portal venous gas due to mesenteric vascular occlusion. ( 6831162 )
1983
17
Mesenteric vascular occlusion. ( 7143293 )
1982
18
Acute mesenteric vascular occlusion: a review of 40 cases. ( 7228544 )
1980
19
Scintiangiographic diagnosis of acute mesenteric vascular occlusion. ( 7371338 )
1980
20
Mesenteric vascular occlusion and varices complicating midgut malrotation. ( 313354 )
1979
21
Bradycardia in acute mesenteric vascular occlusion. ( 728332 )
1978
22
Mesenteric vascular occlusion associated with oral contraceptive use. ( 907467 )
1977
23
Mesenteric vascular occlusion in infants and children: report of two cases and review of the literature. ( 194456 )
1976
24
Acute mesenteric vascular occlusion: A review of thirty-two patients. ( 1188604 )
1975
25
Combined surgical and nutritional management of patients with acute mesenteric vascular occlusion. ( 4813481 )
1974
26
Reversible mesenteric vascular occlusion associated with oral contraceptives. ( 4701037 )
1973
27
Acute mesenteric vascular occlusion occurring on top of chronic localized occlusion. ( 4717050 )
1973
28
Intestinal obstruction due to mesenteric vascular occlusion. ( 5037886 )
1972
29
Intestinal obstruction due to mesenteric vascular occlusion. ( 5096306 )
1971
30
A case of acute inferior mesenteric vascular occlusion. ( 5558179 )
1971
31
Mesenteric vascular occlusion. ( 5254147 )
1969
32
Mesenteric vascular occlusion in pregnancy: suspected ergot poisoning. ( 5373215 )
1969
33
Mesenteric vascular occlusion. Recovery following extensive resection of small and large intestines. ( 5636980 )
1968
34
Intestinal infarction without mesenteric vascular occlusion. A report of 31 cses. ( 5848628 )
1965
35
INFERIOR MESENTERIC VASCULAR OCCLUSION. ( 14252140 )
1965
36
PRIMARY MACROGLOBULINEMIA: DEATH DUE TO MESENTERIC VASCULAR OCCLUSION WITH GAS IN THE PORTAL VENOUS SYSTEM. ( 14226112 )
1964
37
MESENTERIC VASCULAR OCCLUSION IN LATE PREGNANCY. ( 14114366 )
1964
38
Portal gas embolism: a prognostic sign in mesenteric vascular occlusion. ( 13984101 )
1963
39
Mesenteric vascular occlusion: analysis of a series of cases and report of a successful embolectomy. ( 13985248 )
1963
40
SURVIVAL AFTER MESENTERIC RESECTION FOR BOWEL INFARCTION FROM MESENTERIC VASCULAR OCCLUSION. ( 14044590 )
1963
41
MESENTERIC VASCULAR OCCLUSION--REPORT OF TWO CASES. ( 14059589 )
1963
42
ACUTE INTESTINAL INFARCTION: ACUTE MESENTERIC VASCULAR OCCLUSION. ( 14059860 )
1963
43
ACUTE MESENTERIC VASCULAR OCCLUSION TREATED WITH EMBOLECTOMY. ( 14062922 )
1963
44
Mesenteric vascular occlusion in children. ( 13885373 )
1962
45
Primary mesenteric vascular occlusion. ( 13757086 )
1961
46
Mesenteric vascular occlusion: a diagnostic and therapeutic challege. ( 13788505 )
1961
47
Mesenteric vascular occlusion in infancy and childhood. Review of the literature and report of an additional case. ( 14474118 )
1961
48
Mesenteric vascular occlusion. ( 13717181 )
1960
49
Antibiotic therapy in acute mesenteric vascular occlusion. ( 13737480 )
1960
50
Mesenteric vascular occlusion in infancy and childhood. ( 13739753 )
1960

Variations for Mesenteric Vascular Occlusion

Expression for Mesenteric Vascular Occlusion

Search GEO for disease gene expression data for Mesenteric Vascular Occlusion.

Pathways for Mesenteric Vascular Occlusion

Pathways related to Mesenteric Vascular Occlusion according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.47 F2 F7 MTHFR
2 9.8 F2 F7

GO Terms for Mesenteric Vascular Occlusion

Biological processes related to Mesenteric Vascular Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell differentiation GO:0045596 9.32 FGF10 HOPX
2 response to hormone GO:0009725 9.26 F7 MB
3 hemostasis GO:0007599 9.16 F2 F7
4 response to hypoxia GO:0001666 9.13 F7 MB MTHFR
5 positive regulation of blood coagulation GO:0030194 8.62 F2 F7

Sources for Mesenteric Vascular Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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