MCID: MSN003
MIFTS: 33

Mesenteric Vascular Occlusion

Categories: Cardiovascular diseases

Aliases & Classifications for Mesenteric Vascular Occlusion

MalaCards integrated aliases for Mesenteric Vascular Occlusion:

Name: Mesenteric Vascular Occlusion 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:13252
MeSH 44 D008641
UMLS 73 C0025472

Summaries for Mesenteric Vascular Occlusion

MalaCards based summary : Mesenteric Vascular Occlusion is related to spinal cord infarction and thrombophlebitis. An important gene associated with Mesenteric Vascular Occlusion is FGF10 (Fibroblast Growth Factor 10), and among its related pathways/superpathways are Folate Metabolism and Gamma carboxylation, hypusine formation and arylsulfatase activation. The drugs Dalteparin and Heparin have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and spinal cord, and related phenotypes are growth/size/body region and mortality/aging

Related Diseases for Mesenteric Vascular Occlusion

Diseases related to Mesenteric Vascular Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Related Disease Score Top Affiliating Genes
1 spinal cord infarction 29.5 F2 MTHFR
2 thrombophlebitis 29.4 F2 MTHFR
3 thrombophilia due to thrombin defect 29.1 F2 MTHFR
4 thrombosis 28.6 F2 MTHFR
5 pleuropulmonary blastoma 10.4 FGF10 MB
6 subendocardial myocardial infarction 10.3 F2 MB
7 compartment syndrome 10.2 F2 MB
8 cavernous hemangioma 10.2 F2 MB
9 anterior cranial fossa meningioma 10.1 F2 F7
10 visual agnosia 10.1 F7 MB
11 inherited blood coagulation disease 10.1 F2 F7
12 prothrombin deficiency 10.1 F2 F7
13 ischemic heart disease 10.1 F2 F7
14 hemophilia 10.1 F2 F7
15 factor vii deficiency 10.0 F2 F7
16 hemophilia b 10.0 F2 F7
17 factor x deficiency 10.0 F2 F7
18 factor v deficiency 10.0 F2 F7
19 livedoid vasculopathy 9.9 F2 MTHFR
20 sudden sensorineural hearing loss 9.9 F2 MTHFR
21 blood protein disease 9.9 F2 MTHFR
22 ischemic neuropathy 9.9 F2 MTHFR
23 cryptogenic cirrhosis 9.9 F2 MTHFR
24 porencephaly 9.9 F2 MTHFR
25 retinal artery occlusion 9.9 F2 MTHFR
26 marantic endocarditis 9.9 F2 MTHFR
27 intestinal obstruction 9.9
28 intestinal benign neoplasm 9.9 MTHFR ODC1
29 buerger disease 9.9 F2 MTHFR
30 hepatic infarction 9.9 F2 MTHFR
31 retinal vascular occlusion 9.9 F2 MTHFR
32 antithrombin iii deficiency 9.9 F2 MTHFR
33 hemorrhagic disease 9.9 F2 F7
34 central retinal vein occlusion 9.9 F2 MTHFR
35 cervical intraepithelial neoplasia 9.9 MTHFR ODC1
36 branch retinal artery occlusion 9.8 F2 MTHFR
37 patent foramen ovale 9.8 F2 MTHFR
38 arteritic anterior ischemic optic neuropathy 9.8 F2 MTHFR
39 hepatic vascular disease 9.8 F2 MTHFR
40 protein s deficiency 9.8 F2 MTHFR
41 vein disease 9.8 F2 MTHFR
42 placental abruption 9.8 F2 MTHFR
43 thrombasthenia 9.8 F2 MTHFR
44 protein c deficiency 9.8 F2 MTHFR
45 ischemic optic neuropathy 9.8 F2 MTHFR
46 intracranial hypertension 9.8 F2 MTHFR
47 retinal vein occlusion 9.8 F2 MTHFR
48 thrombophilia due to activated protein c resistance 9.8 F2 MTHFR
49 nutritional deficiency disease 9.8 F2 MTHFR
50 colorectal adenoma 9.7 MTHFR ODC1

Graphical network of the top 20 diseases related to Mesenteric Vascular Occlusion:



Diseases related to Mesenteric Vascular Occlusion

Symptoms & Phenotypes for Mesenteric Vascular Occlusion

MGI Mouse Phenotypes related to Mesenteric Vascular Occlusion:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.43 F7 FGF10 MB MTHFR ODC1 F2
2 mortality/aging MP:0010768 9.1 F2 F7 FGF10 MB MTHFR ODC1

Drugs & Therapeutics for Mesenteric Vascular Occlusion

Drugs for Mesenteric Vascular Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dalteparin Approved Phase 4 9005-49-6
2
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
3 Anticoagulants Phase 4
4 calcium heparin Phase 4
5 Calcium, Dietary Phase 4
6 Fibrinolytic Agents Phase 4
7 Heparin, Low-Molecular-Weight Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Predictive Factors of Intestinal Infraction in Acute Mesenteric Ischemia Completed NCT02645240 Phase 4 Heparin injection
2 Risk Factors and Outcomes of Acute Venous Thromboembolism in Cirrhotic Not yet recruiting NCT03580577

Search NIH Clinical Center for Mesenteric Vascular Occlusion

Cochrane evidence based reviews: mesenteric vascular occlusion

Genetic Tests for Mesenteric Vascular Occlusion

Anatomical Context for Mesenteric Vascular Occlusion

MalaCards organs/tissues related to Mesenteric Vascular Occlusion:

41
Colon, Small Intestine, Spinal Cord

Publications for Mesenteric Vascular Occlusion

Articles related to Mesenteric Vascular Occlusion:

(show top 50) (show all 116)
# Title Authors Year
1
Rectus sheath block for postoperative analgesia in patients with mesenteric vascular occlusion undergoing laparotomy: A randomized single-blinded study. ( 27746544 )
2016
2
Mesenteric vascular occlusion: comparison of ancillary CT findings between arterial and venous occlusions and independent CT findings suggesting life-threatening events. ( 23323029 )
2013
3
Intestinal gangrene due to mesenteric vascular occlusion masquerading as strangulated inguinal hernia. ( 17687510 )
2008
4
Management of mesenteric vascular occlusion. ( 18418524 )
2008
5
Spinal cord infarction following surgery for mesenteric vascular occlusion. ( 18046296 )
2007
6
Colonic atresia without mesenteric vascular occlusion. The role of the fibroblast growth factor 10 signaling pathway. ( 15750935 )
2005
7
Effect of prolonged selective intramesenteric arterial vasodilator therapy on intestinal viability after acute segmental mesenteric vascular occlusion. ( 11420490 )
2001
8
Mesenteric vascular occlusion resulting in intestinal necrosis in children. ( 10945686 )
2000
9
Acute mesenteric vascular occlusion: analysis of 39 patients. ( 9562280 )
1998
10
Mesenteric vascular occlusion: a new diagnostic method using a radiolabeled monoclonal antibody reactive with platelets. ( 2717735 )
1989
11
Laser Doppler flowmetry in experimental mesenteric vascular occlusion. ( 2659544 )
1989
12
Use of trans-serosal PO2 to determine intestinal viability in acute mesenteric vascular occlusion. ( 3595206 )
1987
13
Problems in acute mesenteric vascular occlusion. ( 3731831 )
1986
14
Acute superior mesenteric vascular occlusion following internal herniation of redundant sigmoid colon. ( 3830400 )
1985
15
Phaeochromocytoma presenting as a case of mesenteric vascular occlusion. ( 4086256 )
1985
16
Survival after portal venous gas due to mesenteric vascular occlusion. ( 6831162 )
1983
17
Mesenteric vascular occlusion. ( 7143293 )
1982
18
Scintiangiographic diagnosis of acute mesenteric vascular occlusion. ( 7371338 )
1980
19
Acute mesenteric vascular occlusion: a review of 40 cases. ( 7228544 )
1980
20
Mesenteric vascular occlusion and varices complicating midgut malrotation. ( 313354 )
1979
21
Bradycardia in acute mesenteric vascular occlusion. ( 728332 )
1978
22
Mesenteric vascular occlusion associated with oral contraceptive use. ( 907467 )
1977
23
Mesenteric vascular occlusion in infants and children: report of two cases and review of the literature. ( 194456 )
1976
24
Acute mesenteric vascular occlusion: A review of thirty-two patients. ( 1188604 )
1975
25
Combined surgical and nutritional management of patients with acute mesenteric vascular occlusion. ( 4813481 )
1974
26
Acute mesenteric vascular occlusion occurring on top of chronic localized occlusion. ( 4717050 )
1973
27
Reversible mesenteric vascular occlusion associated with oral contraceptives. ( 4701037 )
1973
28
Intestinal obstruction due to mesenteric vascular occlusion. ( 5037886 )
1972
29
Intestinal obstruction due to mesenteric vascular occlusion. ( 5096306 )
1971
30
A case of acute inferior mesenteric vascular occlusion. ( 5558179 )
1971
31
Mesenteric vascular occlusion. ( 5254147 )
1969
32
Mesenteric vascular occlusion in pregnancy: suspected ergot poisoning. ( 5373215 )
1969
33
Mesenteric vascular occlusion. Recovery following extensive resection of small and large intestines. ( 5636980 )
1968
34
Intestinal infarction without mesenteric vascular occlusion. A report of 31 cses. ( 5848628 )
1965
35
INFERIOR MESENTERIC VASCULAR OCCLUSION. ( 14252140 )
1965
36
MESENTERIC VASCULAR OCCLUSION IN LATE PREGNANCY. ( 14114366 )
1964
37
PRIMARY MACROGLOBULINEMIA: DEATH DUE TO MESENTERIC VASCULAR OCCLUSION WITH GAS IN THE PORTAL VENOUS SYSTEM. ( 14226112 )
1964
38
SURVIVAL AFTER MESENTERIC RESECTION FOR BOWEL INFARCTION FROM MESENTERIC VASCULAR OCCLUSION. ( 14044590 )
1963
39
ACUTE MESENTERIC VASCULAR OCCLUSION TREATED WITH EMBOLECTOMY. ( 14062922 )
1963
40
Portal gas embolism: a prognostic sign in mesenteric vascular occlusion. ( 13984101 )
1963
41
Mesenteric vascular occlusion: analysis of a series of cases and report of a successful embolectomy. ( 13985248 )
1963
42
MESENTERIC VASCULAR OCCLUSION--REPORT OF TWO CASES. ( 14059589 )
1963
43
ACUTE INTESTINAL INFARCTION: ACUTE MESENTERIC VASCULAR OCCLUSION. ( 14059860 )
1963
44
Mesenteric vascular occlusion in children. ( 13885373 )
1962
45
Primary mesenteric vascular occlusion. ( 13757086 )
1961
46
Mesenteric vascular occlusion: a diagnostic and therapeutic challege. ( 13788505 )
1961
47
Mesenteric vascular occlusion in infancy and childhood. Review of the literature and report of an additional case. ( 14474118 )
1961
48
Mesenteric vascular occlusion. ( 13717181 )
1960
49
Findings on plain roentgenograms of the abdomen associated with mesenteric vascular occlusion with a possible new sign of mesenteric venous thrombosis. ( 14426487 )
1960
50
Mesenteric vascular occlusion in infancy and childhood. ( 13739753 )
1960

Variations for Mesenteric Vascular Occlusion

Expression for Mesenteric Vascular Occlusion

Search GEO for disease gene expression data for Mesenteric Vascular Occlusion.

Pathways for Mesenteric Vascular Occlusion

GO Terms for Mesenteric Vascular Occlusion

Cellular components related to Mesenteric Vascular Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Golgi lumen GO:0005796 8.62 F2 F7

Biological processes related to Mesenteric Vascular Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.58 F2 FGF10 ODC1
2 response to estradiol GO:0032355 9.43 F7 FGF10
3 response to hormone GO:0009725 9.37 F7 MB
4 response to hypoxia GO:0001666 9.33 F7 MB MTHFR
5 hemostasis GO:0007599 9.32 F2 F7
6 signal peptide processing GO:0006465 9.26 F2 F7
7 positive regulation of blood coagulation GO:0030194 8.96 F2 F7
8 peptidyl-glutamic acid carboxylation GO:0017187 8.62 F2 F7

Sources for Mesenteric Vascular Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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