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MCID: MTG001
MIFTS: 30

Metagonimiasis

Categories: Rare diseases, Infectious diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Metagonimiasis

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MalaCards integrated aliases for Metagonimiasis:

Name: Metagonimiasis 12 53 15 73
Trematode Infections 44 73
Infection by Metagonimus Yokogawai 12
Metagonimus Yokogawai Infection 53

Classifications:

MalaCards categories:
Global: Rare diseases Infectious diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:884
ICD10 33 B66.8
ICD9CM 35 121.5
MeSH 44 D014201
SNOMED-CT 68 37832003
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Summaries for Metagonimiasis

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Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine by Metagonimus yokogawai. The symptoms are diarrhea and colicky abdominal pain. The heart and brain can also be infected.

MalaCards based summary : Metagonimiasis, also known as trematode infections, is related to distomatosis and clonorchiasis. An important gene associated with Metagonimiasis is SLC2A1 (Solute Carrier Family 2 Member 1). The drugs Praziquantel and Albendazole have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and testes.

Wikipedia : 76 Metagonimiasis is a disease caused by an intestinal trematode, most commonly Metagonimus yokagawai, but... more...

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Related Diseases for Metagonimiasis

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Diseases related to Metagonimiasis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 distomatosis 11.5
2 clonorchiasis 10.2
3 fascioliasis 10.0
4 diabetes mellitus 9.9
5 mastitis 9.8
6 paragonimiasis 9.8
7 opisthorchiasis 9.8
8 schistosomiasis 9.8

Graphical network of the top 20 diseases related to Metagonimiasis:



Diseases related to Metagonimiasis
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Symptoms & Phenotypes for Metagonimiasis

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Drugs & Therapeutics for Metagonimiasis

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Drugs for Metagonimiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 54)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Praziquantel Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 55268-74-1 4891
2
Albendazole Approved, Vet_approved Phase 4,Not Applicable 54965-21-8 2082
3
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
4
Lumefantrine Approved Phase 4 82186-77-4 6437380
5
Artemether Approved Phase 4 71963-77-4 119380 68911
6 Anthelmintics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
7 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
8 Antifungal Agents Phase 4
9 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
10 Antiprotozoal Agents Phase 4,Phase 2,Not Applicable
11 Antimalarials Phase 4,Phase 2
12 Artemether-lumefantrine combination Phase 4
13 Artemisinine Phase 4
14 Artemisinins Phase 4
15 Antimitotic Agents Phase 4,Not Applicable
16
Myrrh Approved, Nutraceutical Phase 3 9000-45-7
17 Vaccines Phase 3,Phase 2,Phase 1
18
Mefloquine Approved, Investigational Phase 2 53230-10-7 4046
19
Sulfadoxine Approved, Investigational Phase 2 2447-57-6 17134
20
Pyrimethamine Approved, Investigational, Vet_approved Phase 2 58-14-0 4993
21 Pharmaceutical Solutions Phase 2
22 Fanasil, pyrimethamine drug combination Phase 2
23
Aluminum hydroxide Approved, Investigational Phase 1 21645-51-2
24
Aluminum sulfate Approved Phase 1 10043-01-3
25 Adjuvants, Immunologic Phase 1
26 Gastrointestinal Agents Phase 1
27 Antacids Phase 1
28 Antibodies Phase 1
29 Immunoglobulins Phase 1
30 Anti-Ulcer Agents Phase 1
31
Ciprofloxacin Approved, Investigational Not Applicable 85721-33-1 2764
32
Doxycycline Approved, Investigational, Vet_approved Not Applicable 564-25-0 54671203
33
Iron Approved Not Applicable 7439-89-6 23925
34
Azithromycin Approved Not Applicable 83905-01-5 55185 447043
35
Formaldehyde Approved, Vet_approved 50-00-0 712
36
Metronidazole Approved Not Applicable 443-48-1 4173
37
Cefuroxime Approved Not Applicable 55268-75-2 5361202 5479529
38
Vitamin C Approved, Nutraceutical Not Applicable 50-81-7 5785 54670067
39
Citric Acid Approved, Nutraceutical, Vet_approved Not Applicable 77-92-9 311
40 Mango Approved, Nutraceutical Not Applicable
41 Trichostatin A Not Applicable
42 Micronutrients Not Applicable
43 Trace Elements Not Applicable
44 Vitamins Not Applicable
45 Antioxidants Not Applicable
46 Protective Agents Not Applicable
47 Liver Extracts Not Applicable
48 Ether
49 cefuroxime axetil Not Applicable
50 Disinfectants

Interventional clinical trials:

(show all 48)
# Name Status NCT ID Phase Drugs
1 Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren in Kassena-Nankana, Ghana Unknown status NCT01459146 Phase 4 Artemether-lumefantrine combination plus albendazole;Artemether-lumefantrine plus Praziquantel plus Albendazole;Albendazole plus Praziquantel
2 Evaluation of Praziquantel Dosage for Treatment of Schistosomiasis in Brazil Completed NCT00403611 Phase 4 Praziquantel 60 mg/kg;Praziquantel 40 mg/kg
3 Effect of Schistosomiasis Mansoni on HIV Susceptibility and Female Genital Immunology Completed NCT02878564 Phase 4 Praziquantel
4 Clinical Trial of Efficacy and Safety of Ergoferon in the Treatment of Viral Intestinal Infections in Children Recruiting NCT03039699 Phase 4 Ergoferon;Placebo
5 Repeated Doses of Praziquantel in Schistosomiasis Treatment (RePST) Not yet recruiting NCT02868385 Phase 4 4x Praziquantel;1x Praziquantel
6 Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis Not yet recruiting NCT02734186 Phase 4 Praziquantel
7 Schistosoma Haematobium Infections and Praziquantel Completed NCT01558336 Phase 3 praziquantel
8 Safety and Efficacy of Mirazid for Schistosomiasis Treatment Completed NCT01529710 Phase 3 Myrrh
9 Efficacy of Bilhvax in Association With Praziquantel for Prevention of Clinical Recurrences of Schistosoma Haematobium Completed NCT00870649 Phase 3
10 The Chinese-made Praziquantel for Treatment of Schistosoma Haematobium Recruiting NCT03133832 Phase 3 Companion Tablet
11 Study of Safety and Immune Response of the Sm14 Vaccine in Adults of Endemic Regions Completed NCT03041766 Phase 2 GLA-SE solution
12 Schistosoma Mansoni Morbidity in Children Aged 1-5 Years Completed NCT01901484 Phase 2 Praziquantel
13 S. Japonicum and Pregnancy Outcomes Completed NCT00486863 Phase 2 Praziquantel
14 Activity of Mefloquine Against Urinary Schistosomiasis Completed NCT01132248 Phase 2 Mefloquine;S/P
15 An Open Label Dose Finding Safety and Efficacy in Children and Infants Infected With Schistosomiasis (S.Mansoni) Recruiting NCT02806232 Phase 2 Biltricide (racemate praziquantel) oral tablets;Racemate Praziquantel ODT;Levo Praziquantel ODT
16 A Phase I Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel® With or Without GLA-AF for Intestinal Schistosomiasis in Healthy Adults Completed NCT02337855 Phase 1
17 Praziquantel-Pharmacokinetic Study Completed NCT01288872 Phase 1 Praziquantel
18 Study to Evaluate the Safety of the Vaccine Prepared sm14 Against Schistosomiasis Completed NCT01154049 Phase 1
19 Clinical Trial of Bilhvax,a Vaccine Candidate Against Schistosomiasis Completed NCT01512277 Phase 1
20 A Phase Ib Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel)(R) With or Without AP 10-701 for Intestinal Schistosomiasis in Healthy Exposed Adults Recruiting NCT03110757 Phase 1
21 Evaluation of Strategies for Improved Uptake of Preventive Treatment for Intestinal Schistosomiasis Unknown status NCT01869465 Not Applicable
22 Antioxidant Supplements in the Reversal of Schistosomal Peri-portal Fibrosis Unknown status NCT01260012 Not Applicable
23 A Study of Co-infections of HIV-1 and Schistosoma Mansoni and Its Impact on Praziquantel Treatment Outcomes Unknown status NCT01541631 Not Applicable Praziquantel and Albendazole;Praziquantel and Albendazole;Praziquantel and Albendazole
24 Using Community-Based Volunteers to Reach Non-Enrolled School Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana Completed NCT00463931
25 Schistosomiasis in Formal and Non-Formal Schools in Uganda: Implications for Control Programmes Completed NCT00463593
26 Iron Supplementation in Schistosomiasis and Soil Transmitted Helminths Control Programmes in Zambia Completed NCT00276224 Not Applicable ferrous sulphate (drug)
27 Arachidonic Acid Treatment Against Schistosomiasis Infection in Children Completed NCT02144389 Not Applicable Praziquantel (PZQ)
28 Health Benefits of Repeated Treatment in Pediatric Schistosomiasis Completed NCT01424410
29 Schistosomiasis in Women of Reproductive Age in Burkina Faso: Implications for Control Completed NCT00463632
30 Women and Children as the Focus for Control of Schistosomiasis Infections in the Irrigations Area of Burkina Faso Completed NCT00463528
31 Evaluation of the Use of a Urin Test Strip to Determine the Spread of Schistosoma Infections in Areas Where Schistosomiasis Infections Are Low in Kenya Completed NCT00463307
32 Effect of Starter Formula on Infection Prevention Completed NCT01880970 Not Applicable
33 The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda Completed NCT00215267 Not Applicable praziquantel
34 Urinary Schistosomiasis Infection Completed NCT00138450
35 Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders Completed NCT02105714
36 Schistosomiasis Effect on Response to Vaccines, Anaemia and Nutritional Status of Children of Northern Senegal Completed NCT01553552
37 Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa Completed NCT03458338
38 Urogenital Schistosomiasis and Sexually Transmitted Infections in Madagascar Completed NCT00713999 Not Applicable Treatment with anti-STI and anti-schistosoma regimens
39 Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery Completed NCT01931826 Not Applicable
40 Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires Completed NCT01214876
41 Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment Completed NCT00414479 praziquantl, iron, ACT
42 Influence of Transmission Season on Outcome of Treatment of Schistosoma Haematobium Infection in Mozambique Completed NCT00231322 Not Applicable praziquantel
43 Schistosomiasis in Senegal Recruiting NCT03187366 Not Applicable
44 Seropositivity and Adverse Birth Events in Migrants From Bilharzia-endemic Areas Recruiting NCT03158298
45 Single-sex Controlled Human Schistosomiasis Infection: Safety and Dose Finding Recruiting NCT02755324 Not Applicable
46 Detection of Schistosomiasis CAA in Travellers After High-risk Water Contact Recruiting NCT02194712
47 Prevention of Female Genital Schistosomiasis (FGS) in Rural High-endemic South Africa Recruiting NCT01154907 Praziquantel
48 Childhood Schistosomiasis: a Novel Strategy Extending the Benefits/Reach of Antihelminthic Treatment Active, not recruiting NCT02495909

Search NIH Clinical Center for Metagonimiasis

Cochrane evidence based reviews: trematode infections

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Genetic Tests for Metagonimiasis

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Anatomical Context for Metagonimiasis

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MalaCards organs/tissues related to Metagonimiasis:

41
Brain, Heart, Testes, Kidney, Liver
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Publications for Metagonimiasis

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Articles related to Metagonimiasis:

(show all 23)
# Title Authors Year
1
Fascioliasis: An Ongoing Zoonotic Trematode Infection. ( 26417603 )
2015
2
Trematode infections in pregnant ewes can predispose to mastitis during the subsequent lactation period. ( 24331730 )
2013
3
Case of metagonimiasis complicated with multiple intracerebral hemorrhages and diabetes mellitus. ( 18360077 )
2008
4
Epidemiological study of clonorchiasis and metagonimiasis along the Geum-gang (River) in Okcheon-gun (county), Korea. ( 11949215 )
2002
5
Clonorchiasis and metagonimiasis in the inhabitants along Talchongang (River), Chungwon-gun. ( 7834244 )
1994
6
Trematode infections. Opisthorchiasis, clonorchiasis, fascioliasis, and paragonimiasis. ( 8254167 )
1993
7
An epidemiological study of metagonimiasis along the upper reaches of the Namhan River. ( 8343462 )
1993
8
Intestinal pathology in human metagonimiasis with ultrastructural observations of parasites. ( 3267367 )
1988
9
Specific IgG antibody responses in experimental cat metagonimiasis. ( 12886065 )
1987
10
Metagonimiasis in Korea. ( 6542397 )
1984
11
Study On The Pathology Of Metagonimiasis In Experimentally Infected Cat Intestine. ( 12902706 )
1981
12
An Epidemiologic Study On Clonorchiasis And Metagonimiasis In Riverside Areas In Korea. ( 12902708 )
1981
13
IX. Helminthiasis. Trematode infections and cestode infections. ( 4614512 )
1974
14
Helminthiasis. Trematode infections. Schistosomiasis: general. ( 4612915 )
1974
15
Summary of recent abstracts. IX. Helminthiasis. Trematode infections (continued) and cestode infections. ( 4594831 )
1973
16
Summary of recent abstracts. IX. Helminthiasis. Trematode infections and Cestode infections. ( 4573395 )
1972
17
Summary of recent abstracts. IX. Helminthiasis. Trematode infections. ( 4562258 )
1972
18
Summary of recent abstracts. IX. Helminthiasis. Trematode infections and cestode infections. ( 4943803 )
1971
19
Summary of recent abstracts. IX. Helminthiasis. Trematode infections. ( 4945419 )
1971
20
Summary of recent abstracts. IX. Helminthiasis. Trematode infections and cestode infections. ( 4944786 )
1971
21
Summary of recent abstracts. IX. Helminthiasis. Trematode infections. ( 4992548 )
1970
22
Helminthiasis. Trematode infections. ( 4899280 )
1969
23
IX. Helminthiasis. Trematode infections. ( 4879273 )
1968
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Variations for Metagonimiasis

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Expression for Metagonimiasis

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Search GEO for disease gene expression data for Metagonimiasis.
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Pathways for Metagonimiasis

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GO Terms for Metagonimiasis

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Cellular components related to Metagonimiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Z disc GO:0030018 8.62 PARVA SLC2A1
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Sources for Metagonimiasis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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