Aliases & Classifications for Methane Production

MalaCards integrated aliases for Methane Production:

Name: Methane Production 57

Characteristics:

OMIM:

57
Inheritance:
unclear
? autosomal recessive


External Ids:

OMIM 57 250650
MedGen 42 C1855163
SNOMED-CT via HPO 69 363406005

Summaries for Methane Production

MalaCards based summary : Methane Production is related to constipation and fish-eye disease. An important gene associated with Methane Production is ALB (Albumin). The drugs Lactulose and Lubiprostone have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and small intestine, and related phenotypes are colon cancer and abnormality of abdomen morphology

Description from OMIM: 250650

Related Diseases for Methane Production

Diseases related to Methane Production via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 constipation 10.3
2 fish-eye disease 10.2
3 irritable bowel syndrome 10.2
4 colorectal cancer 9.9
5 ichthyosis bullosa of siemens 9.9
6 cystic fibrosis 9.9
7 helicobacter pylori infection 9.9
8 body mass index quantitative trait locus 1 9.9
9 myelomeningocele 9.9
10 gastrointestinal system disease 9.9
11 rapidly involuting congenital hemangioma 9.9

Graphical network of the top 20 diseases related to Methane Production:



Diseases related to Methane Production

Symptoms & Phenotypes for Methane Production

Symptoms via clinical synopsis from OMIM:

57
G I:
methane production by colonic flora

Respiratory:
methane excretion
increased methane excretion with colon cancer


Clinical features from OMIM:

250650

Human phenotypes related to Methane Production:

32
# Description HPO Frequency HPO Source Accession
1 colon cancer 32 HP:0003003
2 abnormality of abdomen morphology 32 HP:0001438

Drugs & Therapeutics for Methane Production

Drugs for Methane Production (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lactulose Approved Phase 1 4618-18-2 11333
2
Lubiprostone Approved, Investigational Phase 1 136790-76-6 656719
3 tannic acid Approved Phase 1
4
Benzocaine Approved, Investigational Phase 1 94-09-7, 1994-09-7 2337
5 Cola Phase 1
6
Rifaximin Approved, Investigational Not Applicable 80621-81-4 6436173
7
Neomycin Approved, Vet_approved Not Applicable 1404-04-2 8378
8 Gastrointestinal Agents Not Applicable
9 Anti-Infective Agents Not Applicable
10 Anti-Bacterial Agents Not Applicable
11 Nucleic Acid Synthesis Inhibitors Not Applicable
12 alanine Not Applicable
13
Levan Not Applicable 9013-95-0 22833608

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Study of the Effect of SYN-010 on Subjects With IBS-C Completed NCT02495623 Phase 2 SYN-010 21 mg;SYN-010 42 mg;Placebo
2 Efficacy and Safety of SYN-010 in IBS-C Not yet recruiting NCT03763175 Phase 2 SYN-010 21 mg;SYN-010 42 mg;Placebo
3 Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation. Completed NCT01190020 Phase 1 Lubiprostone;Lubiprostone Control
4 Role of Methane in Glycemic Control Completed NCT01638429 Not Applicable Neomycin and Rifaximin
5 Pilot Study Using a Dietary Intervention for Children With Irritable Bowel Syndrome Completed NCT01018498 Not Applicable
6 Investigation of Alanine in Fructose Intolerance: A Dose Ranging Study Recruiting NCT01185210 Not Applicable
7 Microbiome Fructan Metabolism and Symptoms in Childhood IBS Recruiting NCT02842281 Not Applicable

Search NIH Clinical Center for Methane Production

Genetic Tests for Methane Production

Anatomical Context for Methane Production

MalaCards organs/tissues related to Methane Production:

41
Colon, Testes, Small Intestine

Publications for Methane Production

Articles related to Methane Production:

(show top 50) (show all 861)
# Title Authors Year
1
Comparison of five methods for the estimation of methane production from vented in vitro systems. ( 29797341 )
2019
2
Compositional and structural dynamics of the ruminal microbiota in dairy heifers and its relationship to methane production. ( 29851082 )
2019
3
Improved methane production and energy recovery of post-hydrothermal liquefaction waste water via integration of zeolite adsorption and anaerobic digestion. ( 30227293 )
2019
4
The inhibitory impacts of nano-graphene oxide on methane production from waste activated sludge in anaerobic digestion. ( 30235623 )
2019
5
Modified Anaerobic Digestion Model No. 1 for modeling methane production from food waste in batch and semi-continuous anaerobic digestions. ( 30265950 )
2019
6
Carbon dioxide sequestration and methane production promotion by wollastonite in sludge anaerobic digestion. ( 30340185 )
2019
7
Potential methane production and molecular characterization of bacterial and archaeal communities in a horizontal subsurface flow constructed wetland under cold and warm seasons. ( 30340252 )
2019
8
Effect of manganese oxide-modified biochar addition on methane production and heavy metal speciation during the anaerobic digestion of sewage sludge. ( 30528018 )
2019
9
Co-digestion of solid waste: Towards a simple model to predict methane production. ( 29413937 )
2018
10
An explanation of the methanogenic pathway for methane production in anaerobic digestion of nitrogen-rich materials under mesophilic and thermophilic conditions. ( 29783130 )
2018
11
Co-digestion of food waste and sewage sludge for methane production: Current status and perspective. ( 29861300 )
2018
12
Electrohydrolysis pretreatment for enhanced methane production from lignocellulose waste pulp and paper mill sludge and its kinetics. ( 29306129 )
2018
13
Effects of fumaric acid supplementation on methane production and rumen fermentation in goats fed diets varying in forage and concentrate particle size. ( 29449940 )
2018
14
Thermophilic alkaline fermentation followed by mesophilic anaerobic digestion for efficient hydrogen and methane production from waste activated sludge: Focusing on dynamics of bacterial pathogens as revealed by the combination of metagenomic and qPCR analysis. ( 29330191 )
2018
15
Effect of engineered biocarbon on rumen fermentation, microbial protein synthesis, and methane production in an artificial rumen (RUSITEC) fed a high forage diet. ( 29912357 )
2018
16
Methane production and characteristics of the microbial community in the co-digestion of spent mushroom substrate with dairy manure. ( 29216574 )
2018
17
Differential effects of oilseed supplements on methane production and milk fatty acid concentrations in dairy cows. ( 29914588 )
2018
18
The influence of fat and hemicellulose on methane production and energy utilization in lactating Jersey cattle. ( 29908813 )
2018
19
Two-stage anaerobic fermentation process for bio-hydrogen and bio-methane production from pre-treated organic wastes. ( 29933187 )
2018
20
Real-time recovery strategies for volatile fatty acid-inhibited anaerobic digestion of food waste for methane production. ( 29883850 )
2018
21
Kinetic modelling of methane production during bio-electrolysis from anaerobic co-digestion of sewage sludge and food waste. ( 29775905 )
2018
22
Response of methane production via propionate oxidation to carboxylated multiwalled carbon nanotubes in paddy soil enrichments. ( 29340254 )
2018
23
Influence of Added Nutrients and Substrate Concentration in Biohydrogen Production from Winery Wastewaters Coupled to Methane Production. ( 29911268 )
2018
24
Prediction of enteric methane production, yield and intensity in dairy cattle using an intercontinental database. ( 29450980 )
2018
25
Modeling methane production in anaerobic forward osmosis bioreactor using a modified anaerobic digestion model No. 1. ( 29807328 )
2018
26
Two-step heating mode with the same energy consumption as conventional heating for enhancing methane production during anaerobic digestion of swine wastewater. ( 29306839 )
2018
27
How does free ammonia-based sludge pretreatment improve methane production from anaerobic digestion of waste activated sludge. ( 29778074 )
2018
28
Sunflower Oil and Nannochloropsis oculata Microalgae as Sources of Unsaturated Fatty Acids for Mitigation of Methane Production and Enhancing Diets' Nutritive Value. ( 29397713 )
2018
29
Bioelectrochemically assisted anaerobic digestion system for biogas upgrading and enhanced methane production. ( 29758854 )
2018
30
Flammulina velutipes treatment of non-sterile tall wheat grass for enhancing biodegradability and methane production. ( 29776722 )
2018
31
A pathway for biological methane production using bacterial iron-only nitrogenase. ( 29335552 )
2018
32
Changes in the microbial consortium during dark hydrogen fermentation in a bioelectrochemical system increases methane production during a two-stage process. ( 29977334 )
2018
33
Geochemical and Microbiological Evidence for Microbial Methane Production in Deep Aquifers of the Cretaceous Accretionary Prism. ( 29899169 )
2018
34
Anaerobic digestion of 30-100-year-old boreal lake sedimented fibre from the pulp industry: Extrapolating methane production potential to a practical scale. ( 29407702 )
2018
35
Retraction: Response of methane production via propionate oxidation to carboxylated multiwalled carbon nanotubes in paddy soil enrichments. ( 29377018 )
2018
36
Deep-biosphere methane production stimulated by geofluids in the Nankai accretionary complex. ( 29928689 )
2018
37
Methane Production by Co-Digesting Vinasse and Whey in an AnSBBR: Effect of Mixture Ratio and Feed Strategy. ( 29882192 )
2018
38
Enhancing methane production from lignocellulosic biomass by combined steam-explosion pretreatment and bioaugmentation with cellulolytic bacterium<i>Caldicellulosiruptor bescii</i>. ( 29422947 )
2018
39
A randomized double-blind placebo-controlled trial showing rifaximin to improve constipation by reducing methane production and accelerating colon transit: A pilot study. ( 30406392 )
2018
40
Seeking key microorganisms for enhancing methane production in anaerobic digestion of waste sewage sludge. ( 29696331 )
2018
41
Effects of pure plant secondary metabolites on methane production, rumen fermentation and rumen bacteria populations in vitro. ( 29707819 )
2018
42
Climate-driven shifts in sediment chemistry enhance methane production in northern lakes. ( 29728566 )
2018
43
Enhanced methane production from wheat straw with the assistance of lignocellulolytic microbial consortium TC-5. ( 29729539 )
2018
44
Effects of the inclusion of Moringa oleifera seed on rumen fermentation and methane production in a beef cattle diet using the rumen simulation technique (Rusitec). ( 29954468 )
2018
45
Developing an anaerobic digester with external Zeolite filled column for enhancing methane production from swine manure - A feasibility study. ( 29995574 )
2018
46
Synergetic promotion of syntrophic methane production from anaerobic digestion of complex organic wastes by biochar: Performance and associated mechanisms. ( 30001588 )
2018
47
Aerobic deterioration of corn stalk silage and its effect on methane production and microbial community dynamics in anaerobic digestion. ( 30001590 )
2018
48
Effects of individual and complex ciprofloxacin, fullerene C60, and ZnO nanoparticles on sludge digestion: Methane production, metabolism, and microbial community. ( 30014997 )
2018
49
The influence of copper levels on in vitro ruminal fermentation, bacterial growth and methane production. ( 30033574 )
2018
50
Agave tequilana bagasse for methane production in batch and sequencing batch reactors: Acid catalyst effect, batch optimization and stability of the semi-continuous process. ( 30036810 )
2018

Variations for Methane Production

Expression for Methane Production

Search GEO for disease gene expression data for Methane Production.

Pathways for Methane Production

GO Terms for Methane Production

Sources for Methane Production

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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