Aliases & Classifications for Methane Production

MalaCards integrated aliases for Methane Production:

Name: Methane Production 57

Characteristics:

OMIM:

57
Inheritance:
unclear
? autosomal recessive


HPO:

32
methane production:
Inheritance autosomal recessive inheritance


External Ids:

OMIM 57 250650
MedGen 42 C1855163

Summaries for Methane Production

MalaCards based summary : Methane Production is related to constipation and rapidly involuting congenital hemangioma. An important gene associated with Methane Production is ALB (Albumin). The drugs Lovastatin and Lipid Regulating Agents have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and small intestine, and related phenotypes are colon cancer and abnormality of abdomen morphology

More information from OMIM: 250650

Related Diseases for Methane Production

Graphical network of the top 20 diseases related to Methane Production:



Diseases related to Methane Production

Symptoms & Phenotypes for Methane Production

Human phenotypes related to Methane Production:

32
# Description HPO Frequency HPO Source Accession
1 colon cancer 32 HP:0003003
2 abnormality of abdomen morphology 32 HP:0001438

Symptoms via clinical synopsis from OMIM:

57
G I:
methane production by colonic flora

Respiratory:
methane excretion
increased methane excretion with colon cancer

Clinical features from OMIM:

250650

Drugs & Therapeutics for Methane Production

Drugs for Methane Production (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lovastatin Approved, Investigational Phase 2 75330-75-5 53232
2 Lipid Regulating Agents Phase 2
3 Dihydromevinolin Phase 2
4 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
5 L 647318 Phase 2
6 Hypolipidemic Agents Phase 2
7 Anticholesteremic Agents Phase 2
8 Antimetabolites Phase 2
9
tannic acid Approved Phase 1 1401-55-4
10
Lubiprostone Approved, Investigational Phase 1 136790-76-6 656719
11
Lactulose Approved Phase 1 4618-18-2 11333
12
Benzocaine Approved, Investigational Phase 1 94-09-7, 1994-09-7 2337
13 Cola Phase 1
14
Neomycin Approved, Vet_approved Early Phase 1 1404-04-2 8378
15
Rifaximin Approved, Investigational Early Phase 1 80621-81-4 46783403 6436173
16 Gastrointestinal Agents Early Phase 1
17 Anti-Bacterial Agents Early Phase 1
18 Anti-Infective Agents Early Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multi-Dose Study of the Effect of Two Dosage Strengths of SYN-010 Compared With Placebo on Breath Methane Production in Breath Methane-Positive Subjects With IBS-C Completed NCT02495623 Phase 2 SYN-010 21 mg;SYN-010 42 mg;Placebo
2 Evaluation of the Efficacy and Safety of Single, Daily Oral Doses of SYN-010 Compared to Placebo in Adult Patients With Irritable Bowel Syndrome With Constipation (EASE-DO) Recruiting NCT03763175 Phase 2 SYN-010 21 mg;SYN-010 42 mg;Placebo
3 Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation Completed NCT01190020 Phase 1 Lubiprostone;Lubiprostone Control
4 Methane Production and Glycemic Regulation in Pre-diabetic Subjects: Role of Methane in Glycemic Control Completed NCT01638429 Early Phase 1 Neomycin;Rifaximin

Search NIH Clinical Center for Methane Production

Genetic Tests for Methane Production

Anatomical Context for Methane Production

MalaCards organs/tissues related to Methane Production:

41
Colon, Testes, Small Intestine, Bone, Bone Marrow

Publications for Methane Production

Articles related to Methane Production:

(show top 50) (show all 3831)
# Title Authors PMID Year
1
Flatulence. 8
6772089 1980
2
Breath-methane in patients with cancer of the large bowel. 8
70691 1977
3
Floating stools--flatus versus fat. 8
5015442 1972
4
Factors influencing pulmonary methane excretion in man. An indirect method of studying the in situ metabolism of the methane-producing colonic bacteria. 8
5111441 1971
5
Volume, composition, and source of intestinal gas. 8
5486278 1970
6
Effects of magnetite on anaerobic digestion of swine manure: Attention to methane production and fate of antibiotic resistance genes. 38
31357044 2019
7
Metabolic analysis of efficient methane production from food waste with ethanol pre-fermentation using carbon isotope labeling. 38
31387051 2019
8
Enhanced food waste degradation in integrated two-phase anaerobic digestion: Effect of leachate recirculation ratio. 38
31376669 2019
9
Effect of inoculum concentration on methanogenesis by direct interspecies electron transfer: Performance and microbial community composition. 38
31394488 2019
10
Thermotolerant cellulolytic Clostridiaceae and Lachnospiraceae rich consortium enhanced biogas production from oil palm empty fruit bunches by solid-state anaerobic digestion. 38
31374416 2019
11
Synergistic effect of magnetite and zero-valent iron on anaerobic degradation and methanogenesis of phenol. 38
31377508 2019
12
Effects of steam explosion on lignocellulosic degradation of, and methane production from, corn stover by a co-cultured anaerobic fungus and methanogen. 38
31319215 2019
13
Accelerated bio-methane production rate in thermophilic digestion of cardboard with appropriate biochar: Dose-response kinetic assays, hybrid synergistic mechanism, and microbial networks analysis. 38
31326650 2019
14
Biological pretreatment enhances the activity of functional microorganisms and the ability of methanogenesis during anaerobic digestion. 38
31326651 2019
15
Biochar enabled syntrophic action: Solid state anaerobic digestion of agricultural stubble for enhanced methane production. 38
31272803 2019
16
Anaerobic treatment of oil-contaminated wastewater with methane production using anaerobic moving bed biofilm reactors. 38
31323501 2019
17
Enhancing methane production of anaerobic sludge digestion by microaeration: Enzyme activity stimulation, semi-continuous reactor validation and microbial community analysis. 38
31228743 2019
18
Exploiting the unwanted: Sulphate reduction enables phosphate recovery from energy-rich sludge during anaerobic digestion. 38
31330399 2019
19
Microwave pretreatment of polyacrylamide flocculated waste activated sludge: Effect on anaerobic digestion and polyacrylamide degradation. 38
31302462 2019
20
Effects of stepwise thermal hydrolysis and solid-liquid separation on three different sludge organic matter solubilization and biodegradability. 38
31323507 2019
21
Thermophilic anaerobic digestion: Effect of start-up strategies on performance and microbial community. 38
31203011 2019
22
Digestive performance of sludge with different crop straws in mesophilic anaerobic digestion. 38
31203179 2019
23
Nanoparticle induced biological disintegration: A new phase separated pretreatment strategy on microalgal biomass for profitable biomethane recovery. 38
31203180 2019
24
Microbial communities in co-digestion of food wastes and wastewater biosolids. 38
31207413 2019
25
Progress towards catalyzing electro-methanogenesis in anaerobic digestion process: Fundamentals, process optimization, design and scale-up considerations. 38
31300305 2019
26
Disposal of Fenton sludge with anaerobic digestion and the roles of humic acids involved in Fenton sludge. 38
31362207 2019
27
Anaerobic digestion of blackwater assisted by granular activated carbon: From digestion inhibition to methanogenesis enhancement. 38
31181493 2019
28
Continuous dynamics in anaerobic reactor during bioconversion of rice straw: Rate of substance utilization, biomethane production and changes in microbial community structure. 38
31412461 2019
29
Understanding synergies and trade-offs between water and energy production at landfill sites. 38
31207505 2019
30
Contribution of electrodes and electric current to process stability and methane production during the electro-fermentation of food waste. 38
31146076 2019
31
Improvement of Methane Production from Sugar Beet Wastes Using TiO2 and Fe3O4 Nanoparticles and Chitosan Micropowder Additives. 38
30854605 2019
32
Digestive anatomy, physiology, resting metabolism and methane production of captive maras (Dolichotis patagonum). 38
31146020 2019
33
Mesophilic and thermophilic anaerobic digestion of soybean curd residue for methane production: Characterizing bacterial and methanogen communities and their correlations with organic loading rate and operating temperature. 38
31176202 2019
34
Reutilization of high COD leachate via recirculation strategy for methane production in anaerobic digestion of municipal solid waste: Performance and dynamic of methanogen community. 38
31195363 2019
35
Innovative upflow anaerobic sludge osmotic membrane bioreactor for wastewater treatment. 38
31108413 2019
36
Effects of ferric oxide on the microbial community and functioning during anaerobic digestion of swine manure. 38
31100564 2019
37
Inhibition mitigation and ecological mechanism of mesophilic methanogenesis triggered by supplement of ferroferric oxide in sulfate-containing systems. 38
31152955 2019
38
Plant communities control long term carbon accumulation and biogeochemical gradients in a Patagonian bog. 38
31158628 2019
39
Response of the microbial community to the methanogenic performance of biologically hydrolyzed sewage sludge with variable hydraulic retention times. 38
31158775 2019
40
Adaptation of semi-continuous anaerobic sludge digestion to humic acids. 38
31203038 2019
41
Bioaugmentation strategy for overcoming ammonia inhibition during biomethanation of a protein-rich substrate. 38
31146133 2019
42
Methylamine-specific methyltransferase paralogs in Methanosarcina are functionally distinct despite frequent gene conversion. 38
31053830 2019
43
Direct current triggering enhanced anaerobic treatment of acetyl pyrimidine-containing wastewater in up-flow anaerobic sludge blanket coupled with bioelectrocatalytic system. 38
31151005 2019
44
Effects of replacing wheat starch with glycerol on methane emissions, milk production, and feed efficiency in dairy cows fed grass silage-based diets. 38
31255278 2019
45
Performance of a forward osmotic membrane bioreactor for anaerobic digestion of waste sludge with increasing solid concentration. 38
31176985 2019
46
Techno-economic feasibility of anaerobic digestion of cheese whey in small Italian dairies and effect of ultrasound pre-treatment on methane yield. 38
31202020 2019
47
Semi-continuous anaerobic co-digestion of flotation sludge from broiler chicken slaughter and sweet potato: Nutrients and energy recovery. 38
31150897 2019
48
Herbal feed additives containing essential oil: 1. Impact on the nutritional worth of complete feed in vitro. 38
30989448 2019
49
Effect of bamboo grass (Tiliacora triandra, Diels) pellet supplementation on rumen fermentation characteristics and methane production in Thai native beef cattle. 38
30744355 2019
50
Encapsulated nitrate replacing soybean meal changes in vitro ruminal fermentation and methane production in diets differing in concentrate to forage ratio. 38
31393669 2019

Variations for Methane Production

Expression for Methane Production

Search GEO for disease gene expression data for Methane Production.

Pathways for Methane Production

GO Terms for Methane Production

Sources for Methane Production

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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