Aliases & Classifications for Methane Production

MalaCards integrated aliases for Methane Production:

Name: Methane Production 56

Characteristics:

OMIM:

56
Inheritance:
unclear
? autosomal recessive


HPO:

31
methane production:
Inheritance autosomal recessive inheritance


External Ids:

OMIM 56 250650
MedGen 41 C1855163
SNOMED-CT via HPO 68 258211005 363406005

Summaries for Methane Production

MalaCards based summary : Methane Production is related to constipation and rapidly involuting congenital hemangioma. An important gene associated with Methane Production is ALB (Albumin). The drugs Lovastatin and Hypolipidemic Agents have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and bone, and related phenotypes are colon cancer and abnormality of abdomen morphology

More information from OMIM: 250650

Related Diseases for Methane Production

Diseases related to Methane Production via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
# Related Disease Score Top Affiliating Genes
1 constipation 10.4
2 rapidly involuting congenital hemangioma 10.3
3 irritable bowel syndrome 10.3
4 overgrowth syndrome 10.3
5 diarrhea 10.2
6 colorectal cancer 10.2
7 triiodothyronine receptor auxiliary protein 10.1
8 48,xyyy 10.1
9 ulcerative colitis 10.0
10 anoxia 10.0
11 fibrosis of extraocular muscles, congenital, 1 9.9
12 cystic fibrosis 9.9
13 helicobacter pylori infection 9.9
14 body mass index quantitative trait locus 1 9.9
15 myelomeningocele 9.9
16 mastitis 9.9
17 methemoglobinemia 9.9
18 neurogenic bowel 9.9
19 gastrointestinal system disease 9.9
20 crohn's disease 9.9
21 47,xyy 9.9
22 heavy metal poisoning 9.9
23 acute sensory ataxic neuropathy 9.9

Graphical network of the top 20 diseases related to Methane Production:



Diseases related to Methane Production

Symptoms & Phenotypes for Methane Production

Human phenotypes related to Methane Production:

31
# Description HPO Frequency HPO Source Accession
1 colon cancer 31 HP:0003003
2 abnormality of abdomen morphology 31 HP:0001438

Symptoms via clinical synopsis from OMIM:

56
G I:
methane production by colonic flora

Respiratory:
methane excretion
increased methane excretion with colon cancer

Clinical features from OMIM:

250650

Drugs & Therapeutics for Methane Production

Drugs for Methane Production (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lovastatin Approved, Investigational Phase 2 75330-75-5 53232
2 Hypolipidemic Agents Phase 2
3 Anticholesteremic Agents Phase 2
4 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
5 Dihydromevinolin Phase 2
6 Lipid Regulating Agents Phase 2
7 L 647318 Phase 2
8 Antimetabolites Phase 2
9
Lubiprostone Approved, Investigational Phase 1 136790-76-6 656719
10
tannic acid Approved Phase 1 1401-55-4
11
Benzocaine Approved, Investigational Phase 1 1994-09-7, 94-09-7 2337
12
Lactulose Approved Phase 1 4618-18-2 11333
13 Cola Phase 1
14
Neomycin Approved, Vet_approved Early Phase 1 1404-04-2 8378
15
Rifaximin Approved, Investigational Early Phase 1 80621-81-4 6436173 46783403
16 Gastrointestinal Agents Early Phase 1
17 Anti-Infective Agents Early Phase 1
18 Anti-Bacterial Agents Early Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multi-Dose Study of the Effect of Two Dosage Strengths of SYN-010 Compared With Placebo on Breath Methane Production in Breath Methane-Positive Subjects With IBS-C Completed NCT02495623 Phase 2 SYN-010 21 mg;SYN-010 42 mg;Placebo
2 Evaluation of the Efficacy and Safety of Single, Daily Oral Doses of SYN-010 Compared to Placebo in Adult Patients With Irritable Bowel Syndrome With Constipation (EASE-DO) Recruiting NCT03763175 Phase 2 SYN-010 21 mg;SYN-010 42 mg;Placebo
3 Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation Completed NCT01190020 Phase 1 Lubiprostone;Lubiprostone Control
4 Methane Production and Glycemic Regulation in Pre-diabetic Subjects: Role of Methane in Glycemic Control Completed NCT01638429 Early Phase 1 Neomycin;Rifaximin

Search NIH Clinical Center for Methane Production

Genetic Tests for Methane Production

Anatomical Context for Methane Production

MalaCards organs/tissues related to Methane Production:

40
Colon, Testes, Bone, Small Intestine, Bone Marrow

Publications for Methane Production

Articles related to Methane Production:

(show top 50) (show all 4050)
# Title Authors PMID Year
1
Flatulence. 56
6772089 1980
2
Breath-methane in patients with cancer of the large bowel. 56
70691 1977
3
Floating stools--flatus versus fat. 56
5015442 1972
4
Factors influencing pulmonary methane excretion in man. An indirect method of studying the in situ metabolism of the methane-producing colonic bacteria. 56
5111441 1971
5
Volume, composition, and source of intestinal gas. 56
5486278 1970
6
Factors influencing volatile fatty acids production from food wastes via anaerobic digestion. 61
31880192 2020
7
Anaerobic co-digestion of food waste and sewage sludge under mesophilic and thermophilic conditions: Focusing on synergistic effects on methane production. 61
31978701 2020
8
Construction of novel microbial consortia CS-5 and BC-4 valued for the degradation of catalpa sawdust and chlorophenols simultaneously with enhancing methane production. 61
31945685 2020
9
Effect of ceftiofur on mesophilic anaerobic digestion of dairy manure and the reduction of the cephalosporin-resistance gene cmy-2. 61
31931335 2020
10
Enrichment of specific microbial communities by optimum applied voltages for enhanced methane production by microbial electrosynthesis in anaerobic digestion. 61
31918296 2020
11
Enhanced solubilization of solid organics and methane production by anaerobic digestion of swine manure under nano-bubble water addition. 61
31855661 2020
12
Mild microwaves, ultrasonic and alkaline pretreatments for improving methane production: Impact on biochemical and structural properties of olive pomace. 61
31918150 2020
13
Effects of temperature and inoculation ratio on methane production and nutrient solubility of swine manure anaerobic digestion. 61
31923812 2020
14
Review: Comparative methane production in mammalian herbivores. 61
32024568 2020
15
Methane production by co-digestion of poultry manure and lignocellulosic biomass: Kinetic and energy assessment. 61
31887579 2020
16
Insights into the toxicity of troclocarban to anaerobic digestion: Sludge characteristics and methane production. 61
31740317 2020
17
Cohesive strategy and energy conversion efficiency analysis of bio-hythane production from corncob powder by two-stage anaerobic digestion process. 61
31956057 2020
18
Biomethanation at 45 °C offers high process efficiency and supports hygienisation. 61
31901776 2020
19
Combined simultaneous enzymatic saccharification and comminution (SESC) and anaerobic digestion for sustainable biomethane generation from wood lignocellulose and the biochemical characterization of residual sludge solid. 61
31891856 2020
20
Effects of copper salts on performance, antibiotic resistance genes, and microbial community during thermophilic anaerobic digestion of swine manure. 61
31926471 2020
21
Coupling ammonia nitrogen adsorption and regeneration unit with a high-load anoxic/aerobic process to achieve rapid and efficient pollutants removal for wastewater treatment. 61
31759237 2020
22
Circadian misalignment imposed by nocturnal feeding tends to increase fat deposition in pigs. 61
31771673 2020
23
Exploring the feasibility of sewage treatment by algal-bacterial consortia. 61
31906713 2020
24
Development of an alkaline/acid pre-treatment and anaerobic digestion (APAD) process for methane generation from waste activated sludge. 61
31784169 2020
25
Anaerobic digestion of sludge filtrate using anaerobic baffled reactor assisted by symbionts of short chain fatty acid-oxidation syntrophs and exoelectrogens: Pilot-scale verification. 61
31785560 2020
26
Effects of humic matter on the anaerobic digestion of sewage sludge: New insights from sludge structure. 61
31995876 2020
27
Liquid and solids separation for target resource recovery from thermal hydrolyzed sludge. 61
31927095 2020
28
Effects of different barley and oat varieties on methane production, digestibility, and fermentation pattern in vitro. 61
31785868 2020
29
High Spatiotemporal Dynamics of Methane Production and Emission in Oxic Surface Water. 61
31909604 2020
30
Evaluation of squeezing pretreatment for improving methane production from fresh banana pseudo-stems. 61
31838410 2020
31
Sulfate in anaerobic co-digester accelerates methane production from food waste and waste activated sludge. 61
31835199 2020
32
Impact of goethite dosed continuous stirred tank reactor on continuous methane production at different organic loading rates. 61
31529657 2020
33
Effects of agroindustrial by-product supplementation on dairy goat milk characteristics, nutrient utilization, ruminal fermentation, and methane production. 61
31759599 2020
34
Methane production from food waste via mesophilic anaerobic digestion with ethanol pre-fermentation: Methanogenic pathway and microbial community analyses. 61
31796377 2020
35
Disperser coupled rhamnolipid disintegration of pulp and paper mill waste biosolid: Characterisation, methane production, energy assessment and cost analysis. 61
31830717 2020
36
Enhancement of methane production and antibiotic resistance genes reduction by ferrous chloride during anaerobic digestion of swine manure. 61
31855663 2020
37
Impact of roxithromycin on waste activated sludge anaerobic digestion: Methane production, carbon transformation and antibiotic resistance genes. 61
31757536 2020
38
Kinetics of methane production during anaerobic fermentation of chicken manure with sawdust and fungi pre-treated wheat straw. 61
31678803 2020
39
Acclimation Improves Methane Production from Molasses Wastewater with High Salinity in an Upflow Anaerobic Filter Reactor: Performance and Microbial Community Dynamics. 61
32016903 2020
40
Bio-hydrogen and methane production from two-phase anaerobic digestion of food waste under the scheme of acidogenic off-gas reuse. 61
31767429 2020
41
Effect of biochar and wood ash amendment on biochemical methane production of wastewater sludge from a temperature phase anaerobic digestion process. 61
31787514 2020
42
Enhanced hydrolysis and acidification of cellulose at high loading for methane production via anaerobic digestion supplemented with high mobility nanobubble water. 61
31835146 2020
43
The effects of thiosulfinates on methane production from anaerobic co-digestion of waste activated sludge and food waste and mitigate method. 61
31610350 2020
44
Impact of salinity on anaerobic microbial community structure in high organic loading purified terephthalic acid wastewater treatment system. 61
31518813 2020
45
Enhancement of methanogenic activity in anaerobic digestion of high solids sludge by nano zero-valent iron. 61
31759718 2020
46
Methanogenic biodegradation of C9 to C12n-alkanes initiated by Smithella via fumarate addition mechanism. 61
32008120 2020
47
Sugarcane scum as a novel substrate for rapid biogas production from the non-centrifugal cane sugar agribusiness sector in developing countries. 61
31732416 2020
48
A single microbial electrochemical system for CO2 reduction and simultaneous biogas purification, upgrading and sulfur recovery. 61
31771810 2020
49
Additional function of pasteurisation pretreatment in combination with anaerobic digestion on antibiotic removal. 61
31787508 2020
50
Prediction of anaerobic digestion performance and identification of critical operational parameters using machine learning algorithms. 61
31830658 2020

Variations for Methane Production

Expression for Methane Production

Search GEO for disease gene expression data for Methane Production.

Pathways for Methane Production

GO Terms for Methane Production

Sources for Methane Production

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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