Aliases & Classifications for Methane Production

MalaCards integrated aliases for Methane Production:

Name: Methane Production 56

Characteristics:

OMIM:

56
Inheritance:
unclear
? autosomal recessive


HPO:

31
methane production:
Inheritance autosomal recessive inheritance


External Ids:

OMIM 56 250650
MedGen 41 C1855163
SNOMED-CT via HPO 68 258211005 363406005

Summaries for Methane Production

MalaCards based summary : Methane Production is related to constipation and rapidly involuting congenital hemangioma. An important gene associated with Methane Production is ALB (Albumin). The drugs Lovastatin and Dihydromevinolin have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and small intestine, and related phenotypes are colon cancer and abnormality of abdomen morphology

More information from OMIM: 250650

Related Diseases for Methane Production

Diseases related to Methane Production via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 24)
# Related Disease Score Top Affiliating Genes
1 constipation 10.4
2 rapidly involuting congenital hemangioma 10.4
3 irritable bowel syndrome 10.3
4 overgrowth syndrome 10.3
5 diarrhea 10.2
6 colorectal cancer 10.2
7 triiodothyronine receptor auxiliary protein 10.1
8 48,xyyy 10.1
9 ulcerative colitis 10.0
10 anoxia 10.0
11 fibrosis of extraocular muscles, congenital, 1 9.9
12 hair whorl 9.9
13 cystic fibrosis 9.9
14 helicobacter pylori infection 9.9
15 body mass index quantitative trait locus 1 9.9
16 myelomeningocele 9.9
17 mastitis 9.9
18 methemoglobinemia 9.9
19 neurogenic bowel 9.9
20 gastrointestinal system disease 9.9
21 crohn's disease 9.9
22 47,xyy 9.9
23 heavy metal poisoning 9.9
24 acute sensory ataxic neuropathy 9.9

Graphical network of the top 20 diseases related to Methane Production:



Diseases related to Methane Production

Symptoms & Phenotypes for Methane Production

Human phenotypes related to Methane Production:

31
# Description HPO Frequency HPO Source Accession
1 colon cancer 31 HP:0003003
2 abnormality of abdomen morphology 31 HP:0001438

Symptoms via clinical synopsis from OMIM:

56
G I:
methane production by colonic flora

Respiratory:
methane excretion
increased methane excretion with colon cancer

Clinical features from OMIM:

250650

Drugs & Therapeutics for Methane Production

Drugs for Methane Production (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lovastatin Approved, Investigational Phase 2 75330-75-5 53232
2 Dihydromevinolin Phase 2
3 Hypolipidemic Agents Phase 2
4 Lipid Regulating Agents Phase 2
5 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
6 Anticholesteremic Agents Phase 2
7 Antimetabolites Phase 2
8 L 647318 Phase 2
9
Lubiprostone Approved, Investigational Phase 1 136790-76-6 656719
10
tannic acid Approved Phase 1 1401-55-4
11
Benzocaine Approved, Investigational Phase 1 94-09-7, 1994-09-7 2337
12
Lactulose Approved Phase 1 4618-18-2 11333
13 Cola Phase 1
14
Neomycin Approved, Vet_approved Early Phase 1 1404-04-2 8378
15
Rifaximin Approved, Investigational Early Phase 1 80621-81-4 6436173 46783403
16 Anti-Infective Agents Early Phase 1
17 Anti-Bacterial Agents Early Phase 1
18 Gastrointestinal Agents Early Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multi-Dose Study of the Effect of Two Dosage Strengths of SYN-010 Compared With Placebo on Breath Methane Production in Breath Methane-Positive Subjects With IBS-C Completed NCT02495623 Phase 2 SYN-010 21 mg;SYN-010 42 mg;Placebo
2 Evaluation of the Efficacy and Safety of Single, Daily Oral Doses of SYN-010 Compared to Placebo in Adult Patients With Irritable Bowel Syndrome With Constipation (EASE-DO) Recruiting NCT03763175 Phase 2 SYN-010 21 mg;SYN-010 42 mg;Placebo
3 Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation Completed NCT01190020 Phase 1 Lubiprostone;Lubiprostone Control
4 Methane Production and Glycemic Regulation in Pre-diabetic Subjects: Role of Methane in Glycemic Control Completed NCT01638429 Early Phase 1 Neomycin;Rifaximin

Search NIH Clinical Center for Methane Production

Genetic Tests for Methane Production

Anatomical Context for Methane Production

MalaCards organs/tissues related to Methane Production:

40
Colon, Testes, Small Intestine, Bone Marrow, Bone

Publications for Methane Production

Articles related to Methane Production:

(show top 50) (show all 4224)
# Title Authors PMID Year
1
Flatulence. 56
6772089 1980
2
Breath-methane in patients with cancer of the large bowel. 56
70691 1977
3
Floating stools--flatus versus fat. 56
5015442 1972
4
Factors influencing pulmonary methane excretion in man. An indirect method of studying the in situ metabolism of the methane-producing colonic bacteria. 56
5111441 1971
5
Volume, composition, and source of intestinal gas. 56
5486278 1970
6
Effect of organic compounds on dry anaerobic digestion of food and paper industry wastes. 61
32303143 2020
7
Factors influencing volatile fatty acids production from food wastes via anaerobic digestion. 61
31880192 2020
8
Assessment of substrate biodegradability improvement in anaerobic Co-digestion using a chemometrics-based metabolomic approach. 61
32335442 2020
9
Enhancing the production of biogas through anaerobic co-digestion of agricultural waste and chemical pre-treatments. 61
32387911 2020
10
Improved methane production from corn straw using anaerobically digested sludge pre-augmented by nanobubble water. 61
32413644 2020
11
Using an expended granular sludge bed reactor for advanced anaerobic digestion of food waste pretreated with enzyme: The feasibility and its performance. 61
32417658 2020
12
Effect of zero-valent iron combined with carbon-based materials on the mitigation of ammonia inhibition during anaerobic digestion. 61
32446234 2020
13
A new strategy to recover from volatile fatty acid inhibition in anaerobic digestion by photosynthetic bacteria. 61
32416492 2020
14
Recent progress in integrated fixed-film activated sludge process for wastewater treatment: A review. 61
32510449 2020
15
Establishing practical strategies to run high loading corn stover anaerobic digestion: Methane production performance and microbial responses. 61
32334357 2020
16
Innovative nanocomposite formulations for enhancing biogas and biofertilizers production from anaerobic digestion of organic waste. 61
32289660 2020
17
Fat, oil, and grease (FOG) deposits yield higher methane than FOG in anaerobic co-digestion with waste activated sludge. 61
32510442 2020
18
Coupling self-sustaining air flotation screening with conventional CSTR enhances anaerobic biodegradability of corn stover. 61
32335348 2020
19
Genome-centric microbiome analysis reveals solid retention time (SRT)-shaped species interactions and niche differentiation in food waste and sludge co-digesters. 61
32505886 2020
20
From waste to fuel: Energy recovery from household food waste via its bioconversion to energy carriers based on microbiological processes. 61
32438165 2020
21
Annual microbial community dynamics in a full-scale anaerobic sludge digester from a wastewater treatment plant in Colombia. 61
32305756 2020
22
Bioconversion of bamboo shoot shell to methane assisted by microwave irradiation and fungus metabolism. 61
32408456 2020
23
Stable and high-rate anaerobic co-digestion of food waste and cow manure: Optimisation of start-up conditions. 61
32217437 2020
24
Evolutions of antibiotic resistance genes (ARGs), class 1 integron-integrase (intI1) and potential hosts of ARGs during sludge anaerobic digestion with the iron nanoparticles addition. 61
32247117 2020
25
The removal of microplastics in the wastewater treatment process and their potential impact on anaerobic digestion due to pollutants association. 61
32155494 2020
26
Influence of roxithromycin as antibiotic residue on volatile fatty acids recovery in anaerobic fermentation of waste activated sludge. 61
32244145 2020
27
Influence of temperature on the δ13 C values and distribution of methanotroph-related hopanoids in Sphagnum-dominated peat bogs. 61
32180328 2020
28
Characteristics and mechanisms of H2S production in anaerobic digestion of food waste. 61
32247972 2020
29
Resveratrol affects in vitro rumen fermentation, methane production and prokaryotic community composition in a time- and diet-specific manner. 61
32297431 2020
30
Food selectivity of anaerobic protists and direct evidence for methane production using carbon from prey bacteria by endosymbiotic methanogen. 61
32341474 2020
31
Effects of 2 colostrum and subsequent milk replacer feeding intensities on methane production, rumen development, and performance in young calves. 61
32418697 2020
32
Enhanced volatile fatty acid degradation and methane production efficiency by biochar addition in food waste-sludge co-digestion: A step towards increased organic loading efficiency in co-digestion. 61
32244132 2020
33
Three-stage process for tequila vinasse valorization through sequential lactate, biohydrogen and methane production. 61
32222692 2020
34
The performance evaluation and kinetics response of advanced anaerobic digestion for sewage sludge under different SRT during semi-continuous operation. 61
32251856 2020
35
Modelization of anaerobic processes during co-digestion of slowly biodegradable substrates. 61
32105857 2020
36
Methane emission suppression in flooded soil from Amazonia. 61
32088616 2020
37
Methanogenesis in the Lake Elton saline aquatic system. 61
32533307 2020
38
Micron-sized silica particles in wastewater influenced the distribution of organic matters in sludge and their anaerobic degradation. 61
32213426 2020
39
Acidogenic and methanogenic properties of corn straw silage: Regulation and microbial analysis of two-phase anaerobic digestion. 61
32203869 2020
40
Polystyrene nanoplastics reshape the anaerobic granular sludge for recovering methane from wastewater. 61
32574821 2020
41
The use of non-adapted anaerobic consortium in batch reactors enable to couple polychlorinated biphenyl degradation and community adaptation. 61
30457445 2020
42
Cohesive strength changes of sewer sediments during and after ultrasonic treatment: The significance of bound extracellular polymeric substance and microbial community. 61
32217388 2020
43
Assessment of sonotrode and tube reactors for ultrasonic pre-treatment of two different sewage sludge types. 61
32045834 2020
44
Stimulation of methane production from benzoate with addition of carbon materials. 61
32220738 2020
45
Methane production by anaerobic co-digestion of mixed agricultural waste: cabbage and cauliflower. 61
32408797 2020
46
Methane production in a bioelectrochemistry integrated anaerobic reactor with layered nickel foam electrodes. 61
32574747 2020
47
Methane Production in Soil Environments-Anaerobic Biogeochemistry and Microbial Life between Flooding and Desiccation. 61
32545191 2020
48
Abatement of enteric methane production from lactating Murrah buffaloes (Bubalus bubalis) with improving production performance and immune status through dietary supplementation of composite feed additive. 61
32314293 2020
49
Frequency of diet delivery to dairy cows: Effect on nutrient digestion, rumen fermentation, methane production, nitrogen utilization, and milk production. 61
32534916 2020
50
Effect of quinoid redox mediators during azo dye decolorization by anaerobic sludge: Considering the catalyzing mechanism and the methane production. 61
32574861 2020

Variations for Methane Production

Expression for Methane Production

Search GEO for disease gene expression data for Methane Production.

Pathways for Methane Production

GO Terms for Methane Production

Sources for Methane Production

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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