MCID: MTH049
MIFTS: 16

Methotrexate-Associated Lymphoproliferative Disorders

Categories: Blood diseases, Immune diseases, Rare diseases

Aliases & Classifications for Methotrexate-Associated Lymphoproliferative Disorders

MalaCards integrated aliases for Methotrexate-Associated Lymphoproliferative Disorders:

Name: Methotrexate-Associated Lymphoproliferative Disorders 58
Mtx-Associated Lymphoproliferative Disorders 58
Mtx-Lpd 58

Classifications:

Orphanet: 58  
Rare haematological diseases


External Ids:

ICD10 via Orphanet 33 D47.7
Orphanet 58 ORPHA86904

Summaries for Methotrexate-Associated Lymphoproliferative Disorders

MalaCards based summary : Methotrexate-Associated Lymphoproliferative Disorders, also known as mtx-associated lymphoproliferative disorders, is related to diffuse large b-cell lymphoma and b-cell lymphoma. An important gene associated with Methotrexate-Associated Lymphoproliferative Disorders is CD274 (CD274 Molecule). Affiliated tissues include lymph node and tongue.

Related Diseases for Methotrexate-Associated Lymphoproliferative Disorders

Diseases related to Methotrexate-Associated Lymphoproliferative Disorders via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 19)
# Related Disease Score Top Affiliating Genes
1 diffuse large b-cell lymphoma 10.5
2 b-cell lymphoma 10.5
3 rheumatoid arthritis 10.4
4 lymphoma, hodgkin, classic 10.4
5 lymphoproliferative syndrome 10.4
6 arthritis 10.4
7 lymphoma 10.3
8 angioimmunoblastic t-cell lymphoma 10.3
9 autoimmune disease 10.0
10 ataxia and polyneuropathy, adult-onset 10.0
11 granulomatosis with polyangiitis 10.0
12 peripheral t-cell lymphoma 10.0
13 heavy chain disease 10.0
14 gamma heavy chain disease 10.0
15 polymyositis 10.0
16 osteonecrosis 10.0
17 osteomyelitis 10.0
18 dermatomyositis 10.0
19 osteonecrosis of the jaw 10.0

Graphical network of the top 20 diseases related to Methotrexate-Associated Lymphoproliferative Disorders:



Diseases related to Methotrexate-Associated Lymphoproliferative Disorders

Symptoms & Phenotypes for Methotrexate-Associated Lymphoproliferative Disorders

Drugs & Therapeutics for Methotrexate-Associated Lymphoproliferative Disorders

Search Clinical Trials , NIH Clinical Center for Methotrexate-Associated Lymphoproliferative Disorders

Genetic Tests for Methotrexate-Associated Lymphoproliferative Disorders

Anatomical Context for Methotrexate-Associated Lymphoproliferative Disorders

MalaCards organs/tissues related to Methotrexate-Associated Lymphoproliferative Disorders:

40
Lymph Node, Tongue

Publications for Methotrexate-Associated Lymphoproliferative Disorders

Articles related to Methotrexate-Associated Lymphoproliferative Disorders:

(show top 50) (show all 90)
# Title Authors PMID Year
1
[EBV-positive MTX-associated lymphoproliferative disorder and Ig M myeloma in rheumatoid arthritis]. 61
33592662 2021
2
Methotrexate-associated lymphoproliferative disorder with histopathological features of histiocytic necrotizing lymphadenitis. 61
33269654 2021
3
Cessation of methotrexate and a small intestinal resection provide a good clinical course for a patient with a jejunum perforation induced by a methotrexate-associated lymphoproliferative disorder: a case report. 61
33388058 2021
4
Distinct decrease in peripheral lymphocytes in EBER-positive cases of MTX-LPD. 61
32075469 2021
5
Intraoral localized methotrexate-associated lymphoproliferative disorders concurrent with antiresorptive agent-related osteonecrosis of the jaw: A case report and literature review. 61
33363853 2020
6
Clinicopathological evaluation of methotrexate-associated lymphoproliferative disorders with special focus on Epstein-Barr virus-positive mucocutaneous lesions. 61
33148934 2020
7
Methotrexate-Associated Lymphoproliferative Disorders Mimicking Granulomatosis With Polyangiitis: A Radiological Diagnostic Challenge. 61
33155857 2020
8
A case of bilateral methotrexate-associated diffuse large B-cell lymphomas of the breasts with unique clinical presentation and outcome. 61
32361905 2020
9
Pathological assessment of the lymph node biopsies for lymphadenopathy in rheumatoid arthritis. 61
31571513 2020
10
Methotrexate-associated Lymphoproliferative Disorder in the Liver Resembling Hepatocellular Carcinoma Treated with Transarterial Chemoembolization. 61
32522926 2020
11
Primary Central Nervous System Methotrexate-associated Lymphoproliferative Disorder in a Patient with Rheumatoid Arthritis: Case Report and Review of Literature. 61
32695560 2020
12
The clinical impact of absolute lymphocyte count in peripheral blood among patients with methotrexate - associated lymphoproliferative disorders. 61
32404570 2020
13
Methotrexate-associated lymphoproliferative disorders in the central nervous system and stomach: A case report. 61
32282749 2020
14
Immunohistochemical Assessment of the Diagnostic Utility of PD-L1 (Clone SP142) for Methotrexate-Associated Lymphoproliferative Disorders With an Emphasis of Neoplastic PD-L1 (Clone SP142)-Positive Classic Hodgkin Lymphoma Type. 61
31977037 2020
15
Three different CT and FGD PET/CT findings of pulmonary involvement in methotrexate-associated lymphoproliferative disease. 61
31956414 2020
16
Methotrexate-associated lymphoproliferative disorder demonstrating composite lymphoma of EBV-negative diffuse large B-cell lymphoma and EBV-positive mucocutaneous ulcer. 61
32224560 2020
17
Methotrexate-Associated Lymphoproliferative Disorder Developed Ectopically in the Maxillary Gingiva and Bilateral Lungs. 61
32411253 2020
18
Rheumatoid Arthritis Complicated with Nasal Septum Perforation Due to Methotrexate-associated Lymphoproliferative Disorder. 61
31292392 2019
19
Vanishing Cardiac Tumor: Cardiac Involvement in Methotrexate-Associated Lymphoproliferative Disorders. 61
31623446 2019
20
Clinicopathological features of clinical methotrexate-related lymphoproliferative disorders. 61
30947579 2019
21
Methotrexate-associated lymphoproliferative disorder with hypopituitarism and central diabetes insipidus. 61
31610524 2019
22
Methotrexate-associated lymphoproliferative disorders of T-cell phenotype: clinicopathological analysis of 28 cases. 61
30952973 2019
23
Methotrexate-associated Lymphoproliferative Disorders in Patients With Rheumatoid Arthritis: Clinicopathologic Features and Prognostic Factors. 61
31116708 2019
24
Hepatic methotrexate-associated lymphoproliferative disorders identified by multiple liver tumors: a case report and review of the literature. 61
31242930 2019
25
Endobronchial Manifestation of Methotrexate-induced Lymphoproliferative Disorder. 61
30713318 2019
26
[A Case of Small Bowel Perforation Caused by Malignant Lymphoma after Methotrexate Therapy for Rheumatoid Arthritis]. 61
31164519 2019
27
Methotrexate-associated lymphoproliferative disorder in the stomach and duodenum: a case report. 61
31023238 2019
28
Highly aggressive plasmablastic neoplasms in patients with rheumatoid arthritis treated with methotrexate. 61
30658314 2019
29
Clinical management for other iatrogenic immunodeficiency-associated lymphoproliferative disorders. 61
31257348 2019
30
[Methotrexate-associated lymphoproliferative disorders: clinical aspects]. 61
31484893 2019
31
Immune response in LPD during methotrexate administration (MTX-LPD) in rheumatoid arthritis patients. 61
31866617 2019
32
The potential usefulness of sputum cytology in the conclusive diagnosis of methotrexate-associated lymphoproliferative disorders: A case report. 61
30886720 2019
33
Treatment of advanced stage methotrexate-associated lymphoproliferative disorders (MTX-LPDs) with methotrexate discontinuation. 61
30567235 2018
34
Methotrexate-related lymphoproliferative disorder of the lumbar spine origin presenting with severe low-back pain: case report. 61
30168781 2018
35
Spontaneous regression of a renal mass and multiple lung nodules after methotrexate cessation. 61
32743356 2018
36
The prognostic value of positron emission tomography/computed tomography in rheumatoid arthritis patients with methotrexate-associated lymphoproliferative disorders. 61
29713747 2018
37
Lymphoproliferative disorder in an elderly rheumatoid arthritis patient after longterm oral methotrexate administration: A case report. 61
30155252 2018
38
Lymphoproliferative disorder with pathological fracture of the femur in a patient with rheumatoid arthritis treated with methotrexate: A case report. 61
30101019 2018
39
[Primary central nervous system methotrexate associated lymphoproliferative disorders in a patient with rheumatoid arthritis]. 61
30068810 2018
40
Methotrexate-associated lymphoproliferative disorder complicated by severe acute respiratory failure and ileal perforation:a case report. 61
29925726 2018
41
Methotrexate-associated lymphoproliferative disorders with angioimmunoblastic T-cell lymphoma-like features accompanied by gamma-heavy chain disease in a patient with rheumatoid arthritis. 61
29987858 2018
42
A case of rheumatoid arthritis with methotrexate related lymphoproliferative diseases of the knee. 61
26558294 2018
43
Methotrexate-Associated Lymphoproliferative Disorder: Dermoscopic Features. 61
29928205 2018
44
Clinicopathologic investigation of methotrexate-induced lymphoproliferative disorders, with a focus on regression. 61
28877615 2018
45
Oral Methotrexate-related Lymphoproliferative Disease Presenting with Severe Osteonecrosis of the Jaw: A Case Report and Literature Review. 61
29225245 2018
46
18F-FDG PET-CT in a patient with methotrexate-associated lymphoproliferative disorder. 61
29340266 2018
47
Methotrexate-associated Lymphoproliferative Disorder of the Stomach Presumed to Be Mucosa-associated Lymphoid Tissue Lymphoma. 61
30429434 2018
48
Clinical characteristics of methotrexate-associated lymphoproliferative disorders: relationship between absolute lymphocyte count recovery and spontaneous regression. 61
28676912 2017
49
Prognostic factors of methotrexate-associated lymphoproliferative disorders associated with rheumatoid arthritis and plausible application of biological agents. 61
27846761 2017
50
Methotrexate-Related Lymphoproliferative Disorder Presenting with Severe Swelling of the Elbow Joint: A Case Report. 61
29252894 2017

Variations for Methotrexate-Associated Lymphoproliferative Disorders

Expression for Methotrexate-Associated Lymphoproliferative Disorders

Search GEO for disease gene expression data for Methotrexate-Associated Lymphoproliferative Disorders.

Pathways for Methotrexate-Associated Lymphoproliferative Disorders

GO Terms for Methotrexate-Associated Lymphoproliferative Disorders

Sources for Methotrexate-Associated Lymphoproliferative Disorders

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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