MCID: MTH053
MIFTS: 10

Methotrexate Dose Selection

Categories: Rare diseases

Aliases & Classifications for Methotrexate Dose Selection

MalaCards integrated aliases for Methotrexate Dose Selection:

Name: Methotrexate Dose Selection 58

Classifications:



External Ids:

Orphanet 58 ORPHA565785

Summaries for Methotrexate Dose Selection

MalaCards based summary : Methotrexate Dose Selection is related to obsolete: methotrexate dose selection and methotrexate toxicity. An important gene associated with Methotrexate Dose Selection is GGH (Gamma-Glutamyl Hydrolase), and among its related pathways/superpathways are Metabolism of water-soluble vitamins and cofactors and Folate Metabolism.

Related Diseases for Methotrexate Dose Selection

Diseases related to Methotrexate Dose Selection via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 obsolete: methotrexate dose selection 12.6
2 methotrexate toxicity 9.7 SLC19A1 MTHFR
3 pediatric osteosarcoma 9.7 SLC19A1 MTHFR
4 myelomeningocele 9.6 SLC19A1 MTHFR
5 placental abruption 9.6 SLC19A1 MTHFR
6 childhood leukemia 9.6 SLC19A1 MTHFR
7 omphalocele 9.6 SLC19A1 MTHFR
8 homocysteinemia 9.6 SLC19A1 MTHFR
9 cleft lip 9.5 SLC19A1 MTHFR
10 down syndrome 9.5 SLC19A1 MTHFR
11 cleft palate, isolated 9.4 SLC19A1 MTHFR
12 neural tube defects 9.2 SLC19A1 MTHFR
13 leukemia, acute lymphoblastic 9.2 SLC19A1 MTHFR GGH

Graphical network of the top 20 diseases related to Methotrexate Dose Selection:



Diseases related to Methotrexate Dose Selection

Symptoms & Phenotypes for Methotrexate Dose Selection

Drugs & Therapeutics for Methotrexate Dose Selection

Search Clinical Trials , NIH Clinical Center for Methotrexate Dose Selection

Genetic Tests for Methotrexate Dose Selection

Anatomical Context for Methotrexate Dose Selection

Publications for Methotrexate Dose Selection

Variations for Methotrexate Dose Selection

Expression for Methotrexate Dose Selection

Search GEO for disease gene expression data for Methotrexate Dose Selection.

Pathways for Methotrexate Dose Selection

Pathways related to Methotrexate Dose Selection according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.93 SLC19A1 MTHFR
2
Show member pathways
11.59 SLC19A1 MTHFR
3
Show member pathways
11.31 MTHFR GGH
4
Show member pathways
10.83 MTHFR GGH
5 10.29 SLC19A1 MTHFR GGH

GO Terms for Methotrexate Dose Selection

Biological processes related to Methotrexate Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 8.96 MTHFR GGH
2 folic acid metabolic process GO:0046655 8.62 SLC19A1 MTHFR

Sources for Methotrexate Dose Selection

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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