MCID: MTH061
MIFTS: 11

Methotrexate Toxicity or Dose Selection

Categories: Rare diseases

Aliases & Classifications for Methotrexate Toxicity or Dose Selection

MalaCards integrated aliases for Methotrexate Toxicity or Dose Selection:

Name: Methotrexate Toxicity or Dose Selection 59

Classifications:



External Ids:

Orphanet 59 ORPHA413690

Summaries for Methotrexate Toxicity or Dose Selection

MalaCards based summary : Methotrexate Toxicity or Dose Selection is related to pediatric osteosarcoma and acute lymphoblastic leukemia, childhood. Among its related pathways/superpathways are Metabolism of water-soluble vitamins and cofactors and Folate Metabolism.

Related Diseases for Methotrexate Toxicity or Dose Selection

Diseases related to Methotrexate Toxicity or Dose Selection via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 pediatric osteosarcoma 9.4 MTHFR SLC19A1
2 acute lymphoblastic leukemia, childhood 9.4 MTHFR SLC19A1
3 myelomeningocele 9.3 MTHFR SLC19A1
4 homocysteinemia 9.2 MTHFR SLC19A1
5 acute lymphocytic leukemia 9.1 MTHFR SLC19A1
6 neural tube defects 8.9 MTHFR SLC19A1

Graphical network of the top 20 diseases related to Methotrexate Toxicity or Dose Selection:



Diseases related to Methotrexate Toxicity or Dose Selection

Symptoms & Phenotypes for Methotrexate Toxicity or Dose Selection

Drugs & Therapeutics for Methotrexate Toxicity or Dose Selection

Search Clinical Trials , NIH Clinical Center for Methotrexate Toxicity or Dose Selection

Genetic Tests for Methotrexate Toxicity or Dose Selection

Anatomical Context for Methotrexate Toxicity or Dose Selection

Publications for Methotrexate Toxicity or Dose Selection

Variations for Methotrexate Toxicity or Dose Selection

Expression for Methotrexate Toxicity or Dose Selection

Search GEO for disease gene expression data for Methotrexate Toxicity or Dose Selection.

Pathways for Methotrexate Toxicity or Dose Selection

Pathways related to Methotrexate Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.93 MTHFR SLC19A1
2
Show member pathways
11.59 MTHFR SLC19A1
3
Show member pathways
11.3 GGH MTHFR
4
Show member pathways
11.09 GGH MTHFR
5 10.29 GGH MTHFR SLC19A1

GO Terms for Methotrexate Toxicity or Dose Selection

Biological processes related to Methotrexate Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 8.96 GGH MTHFR
2 folic acid metabolic process GO:0046655 8.62 MTHFR SLC19A1

Sources for Methotrexate Toxicity or Dose Selection

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....