MCID: MCR001
MIFTS: 36

Microcystic Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Microcystic Meningioma

MalaCards integrated aliases for Microcystic Meningioma:

Name: Microcystic Meningioma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4594
MeSH 44 D008579
NCIt 50 C4721
SNOMED-CT 68 19453003 253084001
UMLS 73 C1384408

Summaries for Microcystic Meningioma

MalaCards based summary : Microcystic Meningioma is related to intraventricular meningioma and preretinal fibrosis. An important gene associated with Microcystic Meningioma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Nanog in Mammalian ESC Pluripotency and Pathways in cancer. Affiliated tissues include endothelial and testis, and related phenotypes are cardiovascular system and immune system

Related Diseases for Microcystic Meningioma

Diseases related to Microcystic Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 147)
# Related Disease Score Top Affiliating Genes
1 intraventricular meningioma 10.8 F8 GFAP
2 preretinal fibrosis 10.7 GFAP VEGFA
3 pediatric angiosarcoma 10.7 F8 VEGFA
4 intracranial cysts 10.7 ENO2 GFAP
5 primitive neuroectodermal tumor of the cervix uteri 10.7 ENO2 GFAP
6 melanotic medulloblastoma 10.7 ENO2 GFAP
7 cerebellar medulloblastoma 10.6 ENO2 GFAP
8 central nervous system primitive neuroectodermal neoplasm 10.6 ENO2 GFAP
9 subependymal glioma 10.6 ENO2 GFAP
10 cerebral neuroblastoma 10.6 ENO2 GFAP
11 benign ependymoma 10.6 ENO2 GFAP
12 plexiform schwannoma 10.6 ENO2 GFAP
13 cerebral ventricle cancer 10.6 ENO2 GFAP
14 glomeruloid hemangioma 10.6 FLT1 VEGFA
15 cerebrum cancer 10.6 ENO2 GFAP
16 pineal gland cancer 10.6 ENO2 GFAP
17 melanotic neuroectodermal tumor 10.6 ENO2 GFAP
18 supratentorial cancer 10.6 ENO2 GFAP
19 pineocytoma 10.6 ENO2 GFAP
20 subependymoma 10.6 ENO2 GFAP
21 papillary ependymoma 10.5 ENO2 GFAP
22 epithelioid hemangioendothelioma 10.5 FLT1 VEGFA
23 angiomatous meningioma 10.5 GFAP VEGFA
24 subependymal giant cell astrocytoma 10.5 ENO2 GFAP
25 large cell carcinoma with rhabdoid phenotype 10.5 ENO2 VEGFA
26 central neurocytoma 10.5 ENO2 GFAP
27 granular cell tumor 10.5 ENO2 GFAP
28 cerebral convexity meningioma 10.5 CDH1 GFAP
29 deafness, autosomal recessive 23 10.5 CDH17 GJB2
30 acute hemorrhagic leukoencephalitis 10.5 FLT1 VEGFA
31 lymphangiosarcoma 10.4 F8 VEGFA
32 astroblastoma 10.4 ENO2 GFAP GJB2
33 nervous system disease 10.4 GFAP GJB2 VEGFA
34 dupuytren contracture 10.4 TIMP2 VEGFA
35 hypertrophic scars 10.3 MMP2 TIMP1
36 cystic teratoma 10.3 ENO2 GFAP
37 vitreous disease 10.3 GFAP VEGFA
38 peripartum cardiomyopathy 10.3 FLT1 VEGFA
39 lipodermatosclerosis 10.3 FLT1 TIMP2 VEGFA
40 carcinoid syndrome 10.3 ENO2 VEGFA
41 corneal neovascularization 10.3 FLT1 TIMP2 VEGFA
42 extrahepatic bile duct adenocarcinoma 10.2 CDH1 ENO2
43 goblet cell carcinoid 10.2 CDH1 ENO2
44 hemangioblastoma 10.2 ENO2 GFAP VEGFA
45 cerebellar liponeurocytoma 10.2 ENO2 GFAP
46 diffuse pulmonary fibrosis 10.2 ENO2 TIMP1
47 vulvar intraepithelial neoplasia 10.2 CDH1 MMP2
48 gingival hypertrophy 10.2 MMP9 TIMP2
49 hypotrichosis, congenital, with juvenile macular dystrophy 10.1 CDH1 CDH17
50 cancer-associated retinopathy 10.1 ENO2 FLT1 VEGFA

Graphical network of the top 20 diseases related to Microcystic Meningioma:



Diseases related to Microcystic Meningioma

Symptoms & Phenotypes for Microcystic Meningioma

MGI Mouse Phenotypes related to Microcystic Meningioma:

46 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.15 MMP9 GFAP CDH1 GJB2 MMP2 FLT1
2 immune system MP:0005387 10.14 MMP9 GFAP CDH1 GJB2 CDH17 F8
3 growth/size/body region MP:0005378 10.13 GFAP CDH1 ENO2 GJB2 MMP2 FLT1
4 homeostasis/metabolism MP:0005376 10.13 GFAP CDH1 GJB2 F8 MMP2 FLT1
5 hematopoietic system MP:0005397 10.06 CDH17 F8 MMP2 FLT1 VEGFA MMP9
6 mortality/aging MP:0010768 10.02 FLT1 GFAP CDH1 GJB2 F8 MMP2
7 nervous system MP:0003631 9.86 GFAP ENO2 GJB2 MMP2 FLT1 VEGFA
8 neoplasm MP:0002006 9.72 CDH1 MMP2 VEGFA MMP9 TIMP1
9 normal MP:0002873 9.7 GFAP CDH1 GJB2 MMP2 FLT1 TIMP2
10 reproductive system MP:0005389 9.5 CDH1 GJB2 F8 FLT1 VEGFA MMP9
11 vision/eye MP:0005391 9.1 FLT1 GFAP GJB2 MMP2 VEGFA MMP9

Drugs & Therapeutics for Microcystic Meningioma

Search Clinical Trials , NIH Clinical Center for Microcystic Meningioma

Genetic Tests for Microcystic Meningioma

Anatomical Context for Microcystic Meningioma

MalaCards organs/tissues related to Microcystic Meningioma:

41
Endothelial, Testis

Publications for Microcystic Meningioma

Articles related to Microcystic Meningioma:

(show all 33)
# Title Authors Year
1
Spontaneous subdural hematoma associated with microcystic meningioma: first case report in the literature. ( 28660808 )
2017
2
Microcystic meningioma: difficulties in diagnosis and magnetic resonance imaging findings. ( 28197976 )
2017
3
Reticular Appearance on Gadolinium-enhanced T1- and Diffusion-weighted MRI, and Low Apparent Diffusion Coefficient Values in Microcystic Meningioma Cysts. ( 27405819 )
2016
4
Microcystic meningioma of the calvarium: a series of 9 cases and review of the literature. ( 25517950 )
2015
5
Crush cytology of microcystic meningioma with extensive sclerosis. ( 24627702 )
2014
6
Microcystic Meningioma with Late-phase Accumulation on Thallium-201 single-photon emission computed tomography: Case Report. ( 24418788 )
2014
7
A case of intraosseous microcystic meningioma without a mass lesion. ( 24064568 )
2013
8
Pediatric microcystic meningioma: a clinical, histological, and radiographic case-based review. ( 23250249 )
2013
9
Microcystic meningioma of the fourth ventricle in a dog. ( 20962461 )
2011
10
Microcystic meningioma presenting as a cystic lesion with an enhancing mural nodule in elderly women: report of three cases. ( 21863303 )
2011
11
Ultrastructural profile of microcystic meningioma. ( 19886545 )
2009
12
Microcystic meningioma: importance of obvious hypointensity on T1-weighted magnetic resonance images. ( 18303301 )
2008
13
The role of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in microcystic meningiomas. ( 16786122 )
2006
14
Microcystic meningioma in a dolphin (Delphinus delphis): immunohistochemical and ultrastructural study. ( 17101337 )
2006
15
Acute haemorrhage into a microcystic meningioma leading to cerebral herniation. ( 16455530 )
2005
16
Rapidly growing microcystic meningioma of the middle fossa floor. Case report. ( 15973065 )
2005
17
An ultrastructural and immunohistochemical study of microcystic meningioma with emphasis on matrix proteins and connexin 26 type gap junctions. ( 15693636 )
2004
18
Case report: microcystic meningioma in a 58-year-old man with multicystic meningioangiomatosis. ( 12662324 )
2003
19
Cytology of microcystic meningioma in crush preparation. ( 11002371 )
2000
20
Intraosseous microcystic meningioma. ( 10929419 )
2000
21
Unique radiological appearance of a microcystic meningioma. ( 10550660 )
1999
22
Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptor flt-1 in microcystic meningiomas. ( 10502048 )
1999
23
Microcystic meningioma arising in a mixed germ cell tumor of the testis: a case report. ( 10478675 )
1999
24
Microcystic meningioma without enhancement on neuroimaging--case report. ( 9184440 )
1997
25
Microcystic meningioma. A case report. ( 9008106 )
1996
26
CT appearance of microcystic meningioma. ( 8708058 )
1996
27
Detachment of desmosomes in a microcystic meningioma. ( 8867687 )
1995
28
Microcystic meningioma: clinicopathological features of 6 cases. ( 7984255 )
1994
29
Microcystic meningioma--a rarely occurring morphological variant of meningioma. ( 7889343 )
1994
30
Microcystic meningioma: tumors of arachnoid cap vs trabecular cells. ( 7955665 )
1994
31
Mucin-producing microcystic meningioma: a case report with histochemical and ultrastructural findings. ( 3249185 )
1988
32
Microcystic meningioma of the falx cerebri with numerous palisaded structures: an unusual histological pattern mimicking schwannoma. ( 4082928 )
1985
33
Microcystic meningioma. Clinicopathologic report of eight cases. ( 6687423 )
1983

Variations for Microcystic Meningioma

Expression for Microcystic Meningioma

Search GEO for disease gene expression data for Microcystic Meningioma.

Pathways for Microcystic Meningioma

Pathways related to Microcystic Meningioma according to GeneCards Suite gene sharing:

(show all 27)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.06 CDH1 CDH17 FLT1 TIMP1 TIMP2 VEGFA
2 12.64 CDH1 MMP2 MMP9 VEGFA
3
Show member pathways
12.56 CDH1 MMP2 MMP9 VEGFA
4
Show member pathways
12.55 CDH1 MMP2 MMP9 TIMP1 TIMP2
5 12 CDH1 MMP2 MMP9 VEGFA
6 11.89 MMP2 MMP9 VEGFA
7 11.88 FLT1 MMP2 VEGFA
8
Show member pathways
11.87 CDH1 FLT1 TIMP1 TIMP2
9 11.85 CDH1 CDH17 MMP2 MMP9
10 11.76 MMP2 MMP9 TIMP1 VEGFA
11 11.67 ENO2 FLT1 TIMP1 VEGFA
12 11.62 CDH1 MMP2 MMP9
13
Show member pathways
11.62 MMP2 MMP9 TIMP1 TIMP2
14 11.5 MMP2 MMP9 TIMP1
15
Show member pathways
11.49 MMP2 MMP9 VEGFA
16 11.42 CDH1 MMP2 MMP9 VEGFA
17 11.3 FLT1 MMP2 MMP9 TIMP1 TIMP2
18 11.24 MMP2 MMP9 TIMP1 TIMP2
19 11.14 MMP2 MMP9
20
Show member pathways
11.1 TIMP1 VEGFA
21 11.03 FLT1 VEGFA
22 11.02 MMP2 MMP9
23 11.01 MMP9 TIMP1 TIMP2
24 10.96 MMP2 MMP9
25 10.86 TIMP1 VEGFA
26
Show member pathways
10.77 FLT1 VEGFA
27 10.3 FLT1 MMP9 TIMP2 VEGFA

GO Terms for Microcystic Meningioma

Cellular components related to Microcystic Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 9.56 MMP2 MMP9 TIMP1 TIMP2
2 extracellular region GO:0005576 9.56 CDH1 F8 FLT1 MMP2 MMP9 TIMP1
3 platelet alpha granule lumen GO:0031093 9.33 F8 TIMP1 VEGFA
4 astrocyte projection GO:0097449 9.32 GFAP GJB2
5 extracellular space GO:0005615 9.23 ENO2 F8 FLT1 MMP2 MMP9 TIMP1

Biological processes related to Microcystic Meningioma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.63 GJB2 TIMP1 TIMP2
2 cytokine-mediated signaling pathway GO:0019221 9.56 MMP2 MMP9 TIMP1 VEGFA
3 platelet degranulation GO:0002576 9.54 F8 TIMP1 VEGFA
4 response to organic substance GO:0010033 9.5 CDH1 TIMP1 TIMP2
5 endodermal cell differentiation GO:0035987 9.49 MMP2 MMP9
6 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.48 FLT1 VEGFA
7 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.43 FLT1 VEGFA
8 macrophage differentiation GO:0030225 9.4 MMP9 VEGFA
9 negative regulation of membrane protein ectodomain proteolysis GO:0051045 9.16 TIMP1 TIMP2
10 extracellular matrix disassembly GO:0022617 9.02 CDH1 MMP2 MMP9 TIMP1 TIMP2
11 negative regulation of metallopeptidase activity GO:1905049 8.96 TIMP1 TIMP2

Molecular functions related to Microcystic Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.76 CDH1 CDH17 ENO2 F8 MMP2 MMP9
2 identical protein binding GO:0042802 9.65 CDH1 GFAP GJB2 MMP9 VEGFA
3 metalloendopeptidase inhibitor activity GO:0008191 8.96 TIMP1 TIMP2
4 integrin binding GO:0005178 8.8 CDH17 GFAP TIMP2

Sources for Microcystic Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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