MCID: MCR001
MIFTS: 35

Microcystic Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Microcystic Meningioma

MalaCards integrated aliases for Microcystic Meningioma:

Name: Microcystic Meningioma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4594
MeSH 44 D008579
NCIt 50 C4721
SNOMED-CT 68 19453003
UMLS 73 C1384408

Summaries for Microcystic Meningioma

MalaCards based summary : Microcystic Meningioma is related to intraventricular meningioma and cogan syndrome. An important gene associated with Microcystic Meningioma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Nanog in Mammalian ESC Pluripotency and SMAD Signaling Network. Affiliated tissues include lung, brain and kidney, and related phenotypes are cardiovascular system and hematopoietic system

Related Diseases for Microcystic Meningioma

Diseases related to Microcystic Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 115)
# Related Disease Score Top Affiliating Genes
1 intraventricular meningioma 10.2 F8 GFAP
2 cogan syndrome 10.2 GFAP GJB2
3 preretinal fibrosis 10.2 GFAP VEGFA
4 fungal keratitis 10.2 TIMP1 TIMP2
5 pediatric angiosarcoma 10.2 F8 VEGFA
6 deafness, autosomal recessive 23 10.2 CDH17 GJB2
7 angiomatous meningioma 10.1 GFAP VEGFA
8 vitreous disease 10.1 GFAP VEGFA
9 intracranial cysts 10.1 ENO2 GFAP
10 primitive neuroectodermal tumor of the cervix uteri 10.1 ENO2 GFAP
11 melanotic medulloblastoma 10.1 ENO2 GFAP
12 cerebellar medulloblastoma 10.1 ENO2 GFAP
13 central nervous system primitive neuroectodermal neoplasm 10.1 ENO2 GFAP
14 angiokeratoma circumscriptum 10.1 FLT1 VEGFA
15 clear cell ependymoma 10.1 ENO2 GFAP
16 glomeruloid hemangioma 10.1 FLT1 VEGFA
17 plexiform schwannoma 10.1 ENO2 GFAP
18 cerebral neuroblastoma 10.1 ENO2 GFAP
19 subependymal glioma 10.1 ENO2 GFAP
20 cerebral ventricle cancer 10.1 ENO2 GFAP
21 pineal gland cancer 10.1 ENO2 GFAP
22 melanotic neuroectodermal tumor 10.1 ENO2 GFAP
23 benign ependymoma 10.1 ENO2 GFAP
24 pineocytoma 10.1 ENO2 GFAP
25 subependymoma 10.1 ENO2 GFAP
26 benign glioma 10.1 ENO2 GFAP
27 skin hemangioma 10.1 FLT1 VEGFA
28 epithelioid hemangioendothelioma 10.1 FLT1 VEGFA
29 papillary ependymoma 10.1 ENO2 GFAP
30 capillary hemangioma 10.1 FLT1 VEGFA
31 central neurocytoma 10.1 ENO2 GFAP
32 dupuytren contracture 10.1 TIMP2 VEGFA
33 granular cell tumor 10.1 ENO2 GFAP
34 retinal artery occlusion 10.1 F8 VEGFA
35 cystic teratoma 10.1 ENO2 GFAP
36 subependymal giant cell astrocytoma 10.1 ENO2 GFAP
37 central nervous system benign neoplasm 10.1 ENO2 GFAP
38 nervous system benign neoplasm 10.1 ENO2 GFAP
39 cerebellar liponeurocytoma 10.1 ENO2 GFAP
40 traumatic brain injury 10.1 ENO2 GFAP
41 brain injury 10.1 ENO2 GFAP
42 horseshoe kidney 10.1 ENO2 GJB2
43 lymphangiosarcoma 10.1 F8 VEGFA
44 medullomyoblastoma 10.1 ENO2 GFAP
45 spinal stenosis 10.1 TIMP1 TIMP2
46 juvenile pilocytic astrocytoma 10.1 ENO2 GFAP
47 ileum cancer 10.1 ENO2 GFAP
48 pericardium cancer 10.1 ENO2 F8
49 adult medulloblastoma 10.1 ENO2 GFAP
50 vitreoretinopathy, neovascular inflammatory 10.1 GFAP TIMP1 TIMP2

Graphical network of the top 20 diseases related to Microcystic Meningioma:



Diseases related to Microcystic Meningioma

Symptoms & Phenotypes for Microcystic Meningioma

MGI Mouse Phenotypes related to Microcystic Meningioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 FLT1 GFAP GJB2 MMP2 TIMP1 TIMP2
2 hematopoietic system MP:0005397 9.87 CDH17 F8 FLT1 MMP2 TIMP1 TIMP2
3 homeostasis/metabolism MP:0005376 9.86 F8 FLT1 GFAP GJB2 MMP2 TIMP1
4 immune system MP:0005387 9.81 CDH17 F8 FLT1 GFAP GJB2 MMP2
5 nervous system MP:0003631 9.5 ENO2 FLT1 GFAP GJB2 MMP2 TIMP2
6 normal MP:0002873 9.1 FLT1 GFAP GJB2 MMP2 TIMP2 VEGFA

Drugs & Therapeutics for Microcystic Meningioma

Search Clinical Trials , NIH Clinical Center for Microcystic Meningioma

Genetic Tests for Microcystic Meningioma

Anatomical Context for Microcystic Meningioma

MalaCards organs/tissues related to Microcystic Meningioma:

41
Lung, Brain, Kidney, Bone, Ovary, Spinal Cord, Cervix

Publications for Microcystic Meningioma

Articles related to Microcystic Meningioma:

(show all 31)
# Title Authors Year
1
Spontaneous subdural hematoma associated with microcystic meningioma: first case report in the literature. ( 28660808 )
2017
2
Microcystic meningioma: difficulties in diagnosis and magnetic resonance imaging findings. ( 28197976 )
2017
3
Reticular Appearance on Gadolinium-enhanced T1- and Diffusion-weighted MRI, and Low Apparent Diffusion Coefficient Values in Microcystic Meningioma Cysts. ( 27405819 )
2016
4
Microcystic meningioma of the calvarium: a series of 9 cases and review of the literature. ( 25517950 )
2015
5
Crush cytology of microcystic meningioma with extensive sclerosis. ( 24627702 )
2014
6
Microcystic Meningioma with Late-phase Accumulation on Thallium-201 single-photon emission computed tomography: Case Report. ( 24418788 )
2014
7
A case of intraosseous microcystic meningioma without a mass lesion. ( 24064568 )
2013
8
Pediatric microcystic meningioma: a clinical, histological, and radiographic case-based review. ( 23250249 )
2013
9
Microcystic meningioma of the fourth ventricle in a dog. ( 20962461 )
2011
10
Microcystic meningioma presenting as a cystic lesion with an enhancing mural nodule in elderly women: report of three cases. ( 21863303 )
2011
11
Ultrastructural profile of microcystic meningioma. ( 19886545 )
2009
12
Microcystic meningioma: importance of obvious hypointensity on T1-weighted magnetic resonance images. ( 18303301 )
2008
13
Microcystic meningioma in a dolphin (Delphinus delphis): immunohistochemical and ultrastructural study. ( 17101337 )
2006
14
Acute haemorrhage into a microcystic meningioma leading to cerebral herniation. ( 16455530 )
2005
15
Rapidly growing microcystic meningioma of the middle fossa floor. Case report. ( 15973065 )
2005
16
An ultrastructural and immunohistochemical study of microcystic meningioma with emphasis on matrix proteins and connexin 26 type gap junctions. ( 15693636 )
2004
17
Case report: microcystic meningioma in a 58-year-old man with multicystic meningioangiomatosis. ( 12662324 )
2003
18
Cytology of microcystic meningioma in crush preparation. ( 11002371 )
2000
19
Intraosseous microcystic meningioma. ( 10929419 )
2000
20
Unique radiological appearance of a microcystic meningioma. ( 10550660 )
1999
21
Microcystic meningioma arising in a mixed germ cell tumor of the testis: a case report. ( 10478675 )
1999
22
Microcystic meningioma without enhancement on neuroimaging--case report. ( 9184440 )
1997
23
Microcystic meningioma. A case report. ( 9008106 )
1996
24
CT appearance of microcystic meningioma. ( 8708058 )
1996
25
Detachment of desmosomes in a microcystic meningioma. ( 8867687 )
1995
26
Microcystic meningioma: clinicopathological features of 6 cases. ( 7984255 )
1994
27
Microcystic meningioma--a rarely occurring morphological variant of meningioma. ( 7889343 )
1994
28
Microcystic meningioma: tumors of arachnoid cap vs trabecular cells. ( 7955665 )
1994
29
Mucin-producing microcystic meningioma: a case report with histochemical and ultrastructural findings. ( 3249185 )
1988
30
Microcystic meningioma of the falx cerebri with numerous palisaded structures: an unusual histological pattern mimicking schwannoma. ( 4082928 )
1985
31
Microcystic meningioma. Clinicopathologic report of eight cases. ( 6687423 )
1983

Variations for Microcystic Meningioma

Expression for Microcystic Meningioma

Search GEO for disease gene expression data for Microcystic Meningioma.

Pathways for Microcystic Meningioma

Pathways related to Microcystic Meningioma according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.92 CDH17 FLT1 TIMP1 TIMP2 VEGFA
2 11.77 FLT1 MMP2 VEGFA
3 11.64 MMP2 TIMP1 VEGFA
4
Show member pathways
11.54 MMP2 TIMP1 TIMP2
5 11.4 FLT1 MMP2 VEGFA
6 11.28 MMP2 TIMP1 TIMP2
7 11.26 ENO2 FLT1 TIMP1 VEGFA
8 11.19 FLT1 VEGFA
9 11.09 FLT1 VEGFA
10
Show member pathways
11.02 TIMP1 VEGFA
11 10.95 FLT1 VEGFA
12 10.92 TIMP1 TIMP2
13 10.87 FLT1 MMP2 TIMP1 TIMP2
14 10.74 TIMP1 VEGFA
15 10.71 FLT1 TIMP2 VEGFA
16
Show member pathways
10.64 FLT1 VEGFA
17 10.56 CDH17 FLT1 GFAP TIMP1 TIMP2

GO Terms for Microcystic Meningioma

Cellular components related to Microcystic Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.8 F8 FLT1 MMP2 TIMP1 TIMP2 VEGFA
2 extracellular matrix GO:0031012 9.46 MMP2 TIMP1 TIMP2 VEGFA
3 astrocyte projection GO:0097449 9.26 GFAP GJB2
4 extracellular space GO:0005615 9.17 ENO2 F8 FLT1 MMP2 TIMP1 TIMP2
5 platelet alpha granule lumen GO:0031093 9.13 F8 TIMP1 VEGFA

Biological processes related to Microcystic Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 angiogenesis GO:0001525 9.63 FLT1 MMP2 VEGFA
2 aging GO:0007568 9.58 GJB2 TIMP1 TIMP2
3 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.43 FLT1 VEGFA
4 platelet degranulation GO:0002576 9.43 F8 TIMP1 VEGFA
5 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.37 FLT1 VEGFA
6 vascular endothelial growth factor signaling pathway GO:0038084 9.32 FLT1 VEGFA
7 negative regulation of membrane protein ectodomain proteolysis GO:0051045 9.16 TIMP1 TIMP2
8 extracellular matrix disassembly GO:0022617 9.13 MMP2 TIMP1 TIMP2
9 negative regulation of metallopeptidase activity GO:1905049 8.62 TIMP1 TIMP2

Molecular functions related to Microcystic Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme inhibitor activity GO:0004857 9.16 TIMP1 TIMP2
2 metalloendopeptidase inhibitor activity GO:0008191 8.96 TIMP1 TIMP2
3 integrin binding GO:0005178 8.8 CDH17 GFAP TIMP2

Sources for Microcystic Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....