MCID: MCR001
MIFTS: 34

Microcystic Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Microcystic Meningioma

MalaCards integrated aliases for Microcystic Meningioma:

Name: Microcystic Meningioma 12 15 17 72

Classifications:



External Ids:

Disease Ontology 12 DOID:4594
MeSH 44 D008579
NCIt 50 C4721
SNOMED-CT 68 19453003
UMLS 72 C1384408

Summaries for Microcystic Meningioma

MalaCards based summary : Microcystic Meningioma is related to meningioma, familial and intraventricular meningioma. An important gene associated with Microcystic Meningioma is RCC1 (Regulator Of Chromosome Condensation 1), and among its related pathways/superpathways are Nanog in Mammalian ESC Pluripotency and Degradation of the extracellular matrix. Affiliated tissues include brain, ovary and testis, and related phenotypes are Reduced mammosphere formation and Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation

Related Diseases for Microcystic Meningioma

Diseases related to Microcystic Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 113, show less)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 31.5 VEGFA GFAP ENO2
2 intraventricular meningioma 30.8 GFAP F8
3 hemangioblastoma 30.6 VEGFA GFAP ENO2
4 renal cell carcinoma, nonpapillary 27.8 VEGFA PAX8 MMP2 FLT1 FGF2 CA9
5 meningioma, radiation-induced 10.8
6 spinal meningioma 10.8
7 secretory meningioma 10.8
8 lymphoplasmacyte-rich meningioma 10.8
9 preretinal fibrosis 10.6 VEGFA GFAP
10 angiokeratoma circumscriptum 10.6 VEGFA FLT1
11 glomeruloid hemangioma 10.6 VEGFA FLT1
12 pediatric angiosarcoma 10.6 VEGFA F8
13 intracranial cysts 10.5 GFAP ENO2
14 primitive neuroectodermal tumor of the cervix uteri 10.5 GFAP ENO2
15 melanotic medulloblastoma 10.5 GFAP ENO2
16 large cell carcinoma with rhabdoid phenotype 10.4 VEGFA ENO2
17 cerebellar medulloblastoma 10.4 GFAP ENO2
18 clear cell ependymoma 10.4 GFAP ENO2
19 central nervous system primitive neuroectodermal neoplasm 10.4 GFAP ENO2
20 cerebral neuroblastoma 10.4 GFAP ENO2
21 plexiform schwannoma 10.4 GFAP ENO2
22 subependymal glioma 10.4 GFAP ENO2
23 sensory organ benign neoplasm 10.4 PAX8 ENO2
24 lipodermatosclerosis 10.4 VEGFA TIMP2 FLT1
25 skin hemangioma 10.4 VEGFA FLT1
26 pineal gland cancer 10.4 GFAP ENO2
27 cornea cancer 10.4 GFAP FGF2
28 cerebral ventricle cancer 10.4 GFAP ENO2
29 benign ependymoma 10.3 GFAP ENO2
30 melanotic neuroectodermal tumor 10.3 GFAP ENO2
31 fungal keratitis 10.3 TIMP2 TIMP1
32 pineocytoma 10.3 GFAP ENO2
33 astroblastoma 10.3 GJB2 GFAP ENO2
34 cancer-associated retinopathy 10.3 VEGFA FLT1 ENO2
35 brain edema 10.3
36 acute mountain sickness 10.3 VEGFA FLT1 ENO2
37 central nervous system cancer 10.2 VEGFA GFAP ENO2
38 nervous system cancer 10.2 VEGFA GFAP ENO2
39 epithelioid hemangioendothelioma 10.2 VEGFA FLT1
40 subependymoma 10.2 GFAP ENO2
41 vitreous disease 10.2 VEGFA GFAP FGF2
42 rare tumor 10.2
43 vascular cancer 10.2 VEGFA FLT1 FGF2
44 breast carcinoma in situ 10.2 VEGFA FLT1 FGF2
45 radiation proctitis 10.2 VEGFA FGF2
46 microvascular complications of diabetes 5 10.2 VEGFA FLT1 FGF2
47 keratitis, hereditary 10.2 VEGFA GJB2 FGF2
48 capillary hemangioma 10.1 VEGFA FLT1
49 ischemic colitis 10.1 VEGFA MMP2
50 dupuytren contracture 10.1 VEGFA TIMP2 FGF2
51 hydrops, lactic acidosis, and sideroblastic anemia 10.1
52 astrocytoma 10.1
53 cerebrum cancer 10.1 VEGFA MMP2 GFAP
54 supratentorial cancer 10.1 VEGFA MMP2 GFAP
55 angiodysplasia 10.1 VEGFA FGF2
56 grade iii astrocytoma 10.1 VEGFA MMP2 GFAP
57 ovary epithelial cancer 10.1 VEGFA PAX8 MMP2
58 malignant ovarian surface epithelial-stromal neoplasm 10.1 VEGFA PAX8 MMP2
59 ovarian cancer 1 10.1 VEGFA PAX8 MMP2
60 juvenile pilocytic astrocytoma 10.0 GFAP FGF2 ENO2
61 deafness, autosomal recessive 23 10.0 GJB2 CDH17
62 nervous system disease 10.0 VEGFA GJB2 GFAP ENO2
63 neuroma 10.0 GFAP FGF2 ENO2
64 adenomyosis 10.0 VEGFA TIMP2 MMP2
65 connective tissue cancer 10.0 VEGFA FGF2 ENO2
66 endocrine gland cancer 10.0 VEGFA PAX8 MMP2
67 conjunctival nevus 10.0 TIMP1 MMP2
68 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.0
69 carotid stenosis 10.0
70 hypothyroidism 10.0
71 hyperostosis 10.0
72 glioblastoma multiforme 10.0
73 neurilemmoma 10.0
74 teratoma 10.0
75 embryonal carcinoma 10.0
76 seminoma 10.0
77 meningothelial meningioma 10.0
78 transitional meningioma 10.0
79 frontal convexity meningioma 10.0
80 germ cells tumors 10.0
81 glioblastoma 10.0
82 mixed germ cell tumor 10.0
83 low-grade astrocytoma 10.0
84 specific language disorder 10.0
85 conjunctivochalasis 9.9 TIMP2 TIMP1 MMP2
86 corneal neovascularization 9.9 VEGFA TIMP2 FLT1 FGF2
87 nasal cavity squamous cell carcinoma 9.9 TIMP2 TIMP1 MMP2
88 renal pelvis carcinoma 9.9 VEGFA PAX8 CA9
89 sorsby fundus dystrophy 9.9 TIMP2 TIMP1 MMP2
90 gliosarcoma 9.9 MMP2 GFAP ENO2
91 aortic aneurysm, familial abdominal, 1 9.9 TIMP2 TIMP1 MMP2
92 respiratory system cancer 9.9 VEGFA MMP2 ENO2
93 inguinal hernia 9.9 TIMP2 TIMP1 MMP2
94 refractive error 9.8 TIMP2 TIMP1 MMP2
95 nodular prostate 9.8 ENO2 CA9
96 hemangioma 9.8 VEGFA FLT1 FGF2 ENO2
97 vitreoretinopathy, neovascular inflammatory 9.8 TIMP2 TIMP1 GFAP FGF2
98 poems syndrome 9.7 VEGFA FGF2
99 gingival overgrowth 9.7 TIMP1 MMP2 FGF2
100 angiomatous meningioma 9.7 VEGFA TFRC MMP11 GFAP FGF2
101 varicose veins 9.7 VEGFA TIMP2 TIMP1 MMP2
102 adamantinoma of long bones 9.5 VEGFA TIMP2 MMP2 FGF2
103 retinal hemangioblastoma 9.5 VEGFA PAX8 ENO2 CA9
104 brain cancer 9.4 VEGFA TFRC GFAP FGF2 ENO2
105 gastric adenocarcinoma 9.4 VEGFA TIMP2 MMP2 CDH17
106 fibrosarcoma 9.4 TIMP2 TIMP1 MMP2 FGF2
107 microvascular complications of diabetes 1 9.3 VEGFA TIMP2 TIMP1 GFAP FLT1 FGF2
108 large intestine cancer 9.2 VEGFA TIMP1 MMP2 FLT1 CDH17
109 esophageal cancer 9.2 VEGFA TIMP1 MMP2 FLT1 FGF2
110 ewing sarcoma 9.0 VEGFA MMP2 GFAP FLT1 FGF2 ENO2
111 squamous cell carcinoma, head and neck 8.8 VEGFA TIMP2 MMP2 FGF2 CA9
112 lung cancer 8.1 VEGFA TIMP2 TIMP1 MMP2 FLT1 ENO2
113 breast cancer 7.7 VEGFA TIMP2 TIMP1 MMP2 MMP11 FLT1

Graphical network of the top 20 diseases related to Microcystic Meningioma:



Diseases related to Microcystic Meningioma

Symptoms & Phenotypes for Microcystic Meningioma

GenomeRNAi Phenotypes related to Microcystic Meningioma according to GeneCards Suite gene sharing:

26 (showing 2, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.43 CA9 MMP2 PAX8 TFRC TIMP1 TIMP2
2 Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation GR00016-A 8.92 CA9 ENO2 TFRC TIMP2

MGI Mouse Phenotypes related to Microcystic Meningioma:

46 (showing 8, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.17 FGF2 FLT1 GFAP GJB2 MMP11 MMP2
2 homeostasis/metabolism MP:0005376 10.15 F8 FGF2 FLT1 GFAP GJB2 MMP11
3 hematopoietic system MP:0005397 10.1 CA9 CDH17 F8 FGF2 FLT1 MMP2
4 immune system MP:0005387 10.06 CA9 CDH17 F8 FLT1 GFAP GJB2
5 mortality/aging MP:0010768 10 CA9 F8 FGF2 FLT1 GFAP GJB2
6 nervous system MP:0003631 9.85 ENO2 FGF2 FLT1 GFAP GJB2 MMP2
7 normal MP:0002873 9.56 FLT1 GFAP GJB2 MMP2 PAX8 TFRC
8 vision/eye MP:0005391 9.17 FGF2 FLT1 GFAP GJB2 MMP2 PAX8

Drugs & Therapeutics for Microcystic Meningioma

Search Clinical Trials , NIH Clinical Center for Microcystic Meningioma

Genetic Tests for Microcystic Meningioma

Anatomical Context for Microcystic Meningioma

MalaCards organs/tissues related to Microcystic Meningioma:

41
Brain, Ovary, Testis

Publications for Microcystic Meningioma

Articles related to Microcystic Meningioma:

(showing 59, show less)
# Title Authors PMID Year
1
Spontaneous subdural hematoma associated with microcystic meningioma: first case report in the literature. 38
28660808 2019
2
Characteristic features and proposed classification in 69 cases of intracranial microcystic meningiomas. 38
29721630 2019
3
Metastatic Renal Cell Carcinoma to the Brain: A Contemporary Clinicopathologic Analysis With Comparison of Immunohistochemical Profiles to Selected Primary Brain Tumors With Clear Cell Features. 38
30882396 2019
4
Combined 68Ga-NOTA-PRGD2 and 18F-FDG PET/CT Can Discriminate Uncommon Meningioma Mimicking High-Grade Glioma. 38
30052597 2018
5
Meningioma mimicking an intraparenchymal cystic tumor. 38
30214093 2018
6
Reticular Appearance on Gadolinium-enhanced T1- and Diffusion-weighted MRI, and Low Apparent Diffusion Coefficient Values in Microcystic Meningioma Cysts. 38
27405819 2018
7
Microcystic meningioma: difficulties in diagnosis and magnetic resonance imaging findings. 38
28197976 2017
8
Dynamic susceptibility contrast and dynamic contrast-enhanced MRI characteristics to distinguish microcystic meningiomas from traditional Grade I meningiomas and high-grade gliomas. 38
27285539 2017
9
Long-term follow-up of surgical resection of microcystic meningiomas. 38
25677877 2015
10
Microcystic meningioma of the calvarium: a series of 9 cases and review of the literature. 38
25517950 2015
11
Crush cytology of microcystic meningioma with extensive sclerosis. 38
24627702 2014
12
Microcystic variant of an intraosseous meningioma in the frontal area: a case report. 38
25031877 2014
13
Microcystic meningioma with late-phase accumulation on thallium-201 single-photon emission computed tomography: case report. 38
24418788 2014
14
Benign spinal meningioma without dural attachment presenting delayed CSF dissemination and malignant transformation. 38
22915133 2013
15
Low-grade meningioma showing nearly equal density with spinal fluid on radiographic images. 38
23813510 2013
16
Pediatric microcystic meningioma: a clinical, histological, and radiographic case-based review. 38
23250249 2013
17
A case of intraosseous microcystic meningioma without a mass lesion. 38
24064568 2013
18
Microcystic meningioma presenting as a cystic lesion with an enhancing mural nodule in elderly women: report of three cases. 38
21863303 2011
19
Parotid carcinoma metastasis to parietal meningioma: case report and molecular biologic considerations. 38
21159422 2011
20
Microcystic meningioma of the fourth ventricle in a dog. 38
20962461 2011
21
Ultrastructural profile of microcystic meningioma. 38
19886545 2009
22
Tumor-to-tumor metastasis to the central nervous system. 38
18647266 2009
23
Microcystic meningioma: importance of obvious hypointensity on T1-weighted magnetic resonance images. 38
18303301 2008
24
Microcystic meningioma in a dolphin (Delphinus delphis): immunohistochemical and ultrastructural study. 38
17101337 2006
25
The role of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in microcystic meningiomas. 38
16786122 2006
26
Enhancing gliotic cyst wall with microvascular proliferation adjacent to a meningioma. 38
16410217 2006
27
Rapidly growing microcystic meningioma of the middle fossa floor. Case report. 38
15973065 2005
28
Acute haemorrhage into a microcystic meningioma leading to cerebral herniation. 38
16455530 2005
29
Clear cell meningioma: case report and review of the literature. 38
16010490 2005
30
Meningioma in mature cystic teratoma of the ovary. 38
15189511 2004
31
An ultrastructural and immunohistochemical study of microcystic meningioma with emphasis on matrix proteins and connexin 26 type gap junctions. 38
15693636 2004
32
Case report: microcystic meningioma in a 58-year-old man with multicystic meningioangiomatosis. 38
12662324 2003
33
[Microcystic meningiomas: comparison of histology and computed tomography]. 38
12618653 2003
34
[Microcystic meningioma associated with a seizure attack]. 38
12187723 2002
35
[A case of microcystic meningioma with characteristic findings on neuroimaging]. 38
11993166 2002
36
Cytology of microcystic meningioma in crush preparation. 38
11002371 2000
37
Intraosseous microcystic meningioma. 38
10929419 2000
38
Intracerebral cyst associated with meningioma. 38
10622460 1999
39
Microcystic meningioma arising in a mixed germ cell tumor of the testis: a case report. 38
10478675 1999
40
[Atypical neuroradiological features of microcystic meningioma: case report]. 38
10396741 1999
41
Unique radiological appearance of a microcystic meningioma. 38
10550660 1999
42
Pericellular deposition of basement membrane material in myxoid meningioma: immunohistochemical evidence for unbalanced production of type IV collagen and laminin. 38
9589465 1998
43
Microcystic meningioma without enhancement on neuroimaging--case report. 38
9184440 1997
44
Microcystic meningioma. A case report. 38
9008106 1996
45
CT appearance of microcystic meningioma. 38
8708058 1996
46
Clear cell meningioma: report of a spinal case. 38
8705792 1996
47
Detachment of desmosomes in a microcystic meningioma. 38
8867687 1995
48
Microcystic meningioma: clinicopathological features of 6 cases. 38
7984255 1994
49
Microcystic meningioma: tumors of arachnoid cap vs trabecular cells. 38
7955665 1994
50
Microcystic meningioma--a rarely occurring morphological variant of meningioma. 38
7889343 1994
51
Meningiomas differentiating to arachnoid trabecular cells: a proposal for histological subtype "arachnoid trabecular cell meningioma". 38
1722606 1991
52
Myxoid meningioma. 38
2382312 1990
53
[An immunohistochemical and ultrastructural study on 76 cases of meningioma]. 38
2636960 1989
54
Mucin-producing microcystic meningioma: a case report with histochemical and ultrastructural findings. 38
3249185 1988
55
[Vacuolated (microcystic) meningioma. Report of two cases]. 38
2457847 1988
56
[Light and electron microscopy of microcystic meningioma. Case report]. 38
2450299 1987
57
Microcystic meningiomas. 38
3308265 1987
58
Microcystic meningioma of the falx cerebri with numerous palisaded structures: an unusual histological pattern mimicking schwannoma. 38
4082928 1985
59
Microcystic meningioma. Clinicopathologic report of eight cases. 38
6687423 1983

Variations for Microcystic Meningioma

Expression for Microcystic Meningioma

Search GEO for disease gene expression data for Microcystic Meningioma.

Pathways for Microcystic Meningioma

Pathways related to Microcystic Meningioma according to GeneCards Suite gene sharing:

(showing 19, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.06 VEGFA TIMP2 TIMP1 FLT1 FGF2 CDH17
2
Show member pathways
12.51 TIMP2 TIMP1 MMP2 MMP11 FGF2
3
Show member pathways
12.5 TIMP2 TIMP1 FLT1 FGF2
4
Show member pathways
12.06 TIMP2 TIMP1 FLT1 FGF2
5
Show member pathways
11.87 TIMP2 TIMP1 FLT1 FGF2
6 11.76 VEGFA TIMP1 MMP2 FGF2
7 11.6 VEGFA GFAP FGF2
8 11.59 VEGFA TIMP1 TFRC FLT1 ENO2
9
Show member pathways
11.55 TIMP2 TIMP1 MMP2 MMP11
10 11.5 VEGFA TFRC CA9
11 11.47 TIMP1 MMP2 FGF2
12 11.44 TIMP2 TIMP1 MMP2
13 11.24 VEGFA FLT1 FGF2
14 11.05 TIMP2 TIMP1 MMP2 FLT1 FGF2 CA9
15 10.91 VEGFA FLT1 FGF2
16 10.91 VEGFA FLT1 FGF2
17 10.85 VEGFA TIMP1
18 10.75 TIMP2 TIMP1 GFAP FLT1 FGF2 CDH17
19 10.64 VEGFA TIMP2 FLT1 FGF2

GO Terms for Microcystic Meningioma

Cellular components related to Microcystic Meningioma according to GeneCards Suite gene sharing:

(showing 5, show less)
# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.81 VEGFA TIMP2 TIMP1 TFRC MMP2 MMP11
2 platelet alpha granule lumen GO:0031093 9.43 VEGFA TIMP1 F8
3 extracellular matrix GO:0031012 9.35 VEGFA TIMP2 TIMP1 MMP2 MMP11
4 astrocyte projection GO:0097449 9.32 GJB2 GFAP
5 extracellular space GO:0005615 9.28 VEGFA TIMP2 TIMP1 TFRC MMP2 FLT1

Biological processes related to Microcystic Meningioma according to GeneCards Suite gene sharing:

(showing 14, show less)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of angiogenesis GO:0045766 9.71 VEGFA FLT1 FGF2
2 cytokine-mediated signaling pathway GO:0019221 9.67 VEGFA TIMP1 MMP2 FGF2
3 platelet degranulation GO:0002576 9.65 VEGFA TIMP1 F8
4 angiogenesis GO:0001525 9.62 VEGFA MMP2 FLT1 FGF2
5 cell migration involved in sprouting angiogenesis GO:0002042 9.52 VEGFA FGF2
6 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.51 VEGFA FLT1
7 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.49 VEGFA PAX8
8 vascular endothelial growth factor signaling pathway GO:0038084 9.46 VEGFA FLT1
9 embryonic morphogenesis GO:0048598 9.43 FLT1 FGF2
10 positive regulation of phospholipase C activity GO:0010863 9.4 FLT1 FGF2
11 positive regulation of MAP kinase activity GO:0043406 9.33 VEGFA FLT1 FGF2
12 negative regulation of membrane protein ectodomain proteolysis GO:0051045 9.26 TIMP2 TIMP1
13 negative regulation of metallopeptidase activity GO:1905049 8.96 TIMP2 TIMP1
14 extracellular matrix disassembly GO:0022617 8.92 TIMP2 TIMP1 MMP2 MMP11

Molecular functions related to Microcystic Meningioma according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 zinc ion binding GO:0008270 9.55 TIMP2 TIMP1 MMP2 MMP11 CA9
2 metalloendopeptidase inhibitor activity GO:0008191 8.96 TIMP2 TIMP1
3 integrin binding GO:0005178 8.8 TIMP2 FGF2 CDH17

Sources for Microcystic Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....