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MCID: MCR011
MIFTS: 43

Microinvasive Gastric Cancer

Categories: Cancer diseases, Gastrointestinal diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Microinvasive Gastric Cancer

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MalaCards integrated aliases for Microinvasive Gastric Cancer:

Name: Microinvasive Gastric Cancer 12 15
Early Gastric Cancer 12 54 15 71
Surface Gastric Cancer 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:10541
NCIt 49 C27131
UMLS 71 C0349530
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Summaries for Microinvasive Gastric Cancer

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MalaCards based summary : Microinvasive Gastric Cancer, also known as early gastric cancer, is related to helicobacter pylori infection and tubular adenocarcinoma, and has symptoms including abdominal pain and dyspepsia. An important gene associated with Microinvasive Gastric Cancer is TDRG1 (Testis Development Related 1), and among its related pathways/superpathways are Gastric acid production and Secretion of Hydrochloric Acid in Parietal Cells. The drugs Clarithromycin and Amoxicillin have been mentioned in the context of this disorder. Affiliated tissues include lymph node, colon and liver, and related phenotype is digestive/alimentary.

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Related Diseases for Microinvasive Gastric Cancer

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Diseases related to Microinvasive Gastric Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 439)
# Related Disease Score Top Affiliating Genes
1 helicobacter pylori infection 31.2 S100A8 MUC6 GAST
2 tubular adenocarcinoma 31.1 MUC5AC CEACAM5 CDX2 CDH1
3 appendix adenocarcinoma 31.1 CEACAM5 CDX2
4 linitis plastica 31.0 CEACAM5 CDX2 CDH1
5 krukenberg carcinoma 30.9 CEACAM5 CDX2
6 gastrointestinal ulceration, recurrent, with dysfunctional platelets 30.9 S100A8 GAST
7 papillary adenocarcinoma 30.9 TP53 CEACAM5 CDH1
8 peptic esophagitis 30.8 S100A8 GAST CDX2 ATP4A ATP12A
9 adenocarcinoma 30.7 VEGFC TP53 MLH1 CEACAM5 CDX2 CDH1
10 small cell carcinoma 30.4 TP53 GAST CDX2
11 pernicious anemia 30.4 GAST ATP4A ATP12A
12 gastrointestinal carcinoma 30.4 TP53 GAST CEACAM5 CDX2
13 vitamin b12 deficiency 30.4 GAST ATP4A ATP12A
14 hernia, hiatus 30.3 GAST ATP4A ATP12A
15 ascending colon cancer 30.3 MLH1 CEACAM5 CDX2
16 marginal zone b-cell lymphoma 30.3 S100A8 ATP4A ATP12A
17 adenoma 30.2 TP53 MUC6 MUC5AC MLH1 CDX2 CDH1
18 gastroesophageal reflux 30.2 TP53 S100A8 GAST CDX2
19 mucinous adenocarcinoma 30.1 TP53 MUC5AC MLH1 CEACAM5 CDX2
20 lymphocytic gastritis 30.1 ATP4A ATP12A
21 in situ carcinoma 30.1 TP53 PDPN CDH1
22 transverse colon cancer 30.1 SERPINB3 MLH1 CEACAM5
23 duodenogastric reflux 30.1 GAST ATP4A ATP12A
24 gastric adenocarcinoma 30.1 VEGFC TP53 S100A8 MLH1 GAST CEACAM5
25 autoimmune gastritis 30.1 GAST ATP4A ATP12A
26 atrophic gastritis 30.1 TP53 TFF2 S100A8 MUC6 GAST CDX2
27 lymphoma, mucosa-associated lymphoid type 30.1 TP53 S100A8 ATP4A ATP12A
28 oropharynx cancer 30.0 TP53 SERPINB3 CDH1
29 gastric tubular adenocarcinoma 30.0 MUC6 MUC5AC CDX2
30 gastric lymphoma 29.9 TP53 S100A8 ATP4A ATP12A
31 intrahepatic cholangiocarcinoma 29.9 TP53 MUC5AC CDX2 CDH1
32 gastritis 29.9 TP53 TFF2 S100A8 MUC6 GAST CDX2
33 bile reflux 29.9 S100A8 MUC5AC GAST CDX2 ATP4A ATP12A
34 intestinal obstruction 29.9 CEACAM5 CDX2 ATP4A ATP12A
35 peptic ulcer disease 29.9 TP53 S100A8 MUC5AC GAST ATP4A ATP12A
36 colorectal adenoma 29.8 TP53 MLH1 CDH1
37 rectum adenocarcinoma 29.8 TP53 MLH1 CEACAM5 CDX2
38 villous adenoma 29.6 MUC6 MUC5AC MLH1 CEACAM5 CDX2
39 cholecystitis 29.5 TP53 S100A8 MUC6 MUC5AC CDH1
40 larynx cancer 29.5 VEGFC TP53 SERPINB3 MIR196A1
41 signet ring cell adenocarcinoma 29.4 TP53 SERPINB3 PDPN MUC6 MUC5AC MLH1
42 cholangiocarcinoma 29.4 VEGFC TP53 MUC5AC CEACAM5 CDX2 CDH1
43 gastric cancer 29.4 XIST VEGFC TP53 TFF2 TDRG1 S100A8
44 pseudomyxoma peritonei 29.1 TP53 MUC6 MUC5AC CEACAM5 CDX2 CDH1
45 esophageal cancer 28.9 XIST VEGFC TP53 SERPINB3 MLH1 MIR196A1
46 colorectal cancer 28.0 XIST VEGFC TP53 PDPN MUC6 MUC5AC
47 pancreatic cancer 27.8 XIST VEGFC TP53 MUC6 MUC5AC MLH1
48 ureter adenocarcinoma 10.6 CEACAM5 CDX2
49 breast cystic hypersecretory carcinoma 10.6 CEACAM5 CDH1
50 mucinous adenofibroma 10.6 CEACAM5 CDX2

Graphical network of the top 20 diseases related to Microinvasive Gastric Cancer:



Diseases related to Microinvasive Gastric Cancer
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Symptoms & Phenotypes for Microinvasive Gastric Cancer

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UMLS symptoms related to Microinvasive Gastric Cancer:


abdominal pain, dyspepsia

MGI Mouse Phenotypes related to Microinvasive Gastric Cancer:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.32 ATP12A ATP4A CDH1 CDX2 GAST MLH1
Sources

Drugs & Therapeutics for Microinvasive Gastric Cancer

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Drugs for Microinvasive Gastric Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 132)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clarithromycin Approved Phase 4 81103-11-9 84029
2
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
3
Pantoprazole Approved Phase 4 102625-70-7 4679
4
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
5
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
6
Metronidazole Approved Phase 4 443-48-1 4173
7
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
8
Dexlansoprazole Approved, Investigational Phase 4 138530-94-6, 103577-45-3 9578005
9
Rabeprazole Approved, Investigational Phase 4 117976-89-3 5029
10
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 4 7487-88-9 24083
11
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
12
Ecabet Investigational Phase 4 33159-27-2, 86408-72-2 65781
13 Analgesics, Non-Narcotic Phase 4
14 Fibrinolytic Agents Phase 4
15 Anti-Inflammatory Agents Phase 4
16 Anti-Inflammatory Agents, Non-Steroidal Phase 4
17 Platelet Aggregation Inhibitors Phase 4
18 Antipyretics Phase 4
19 Cyclooxygenase Inhibitors Phase 4
20 Antirheumatic Agents Phase 4
21 Purinergic P2Y Receptor Antagonists Phase 4
22 Anti-Infective Agents Phase 4
23 Cytochrome P-450 CYP3A Inhibitors Phase 4
24 Cytochrome P-450 Enzyme Inhibitors Phase 4
25 Antiparasitic Agents Phase 4
26 Antiprotozoal Agents Phase 4
27 Anti-Bacterial Agents Phase 4
28 HIV Protease Inhibitors Phase 4
29
protease inhibitors Phase 4
30 Protective Agents Phase 4
31 Gastrointestinal Agents Phase 4
32 Anti-Ulcer Agents Phase 4
33 Proton Pump Inhibitors Phase 4
34 Antacids Phase 4
35 Anesthetics Phase 4
36 Central Nervous System Depressants Phase 4
37 Analgesics Phase 4
38 Hormones Phase 4
39 Tocolytic Agents Phase 4
40 Anti-Arrhythmia Agents Phase 4
41 Anticonvulsants Phase 4
42 Calcium, Dietary Phase 4
43 calcium channel blockers Phase 4
44
Meperidine Approved Phase 3 57-42-1 4058
45
Omeprazole Approved, Investigational, Vet_approved Phase 3 73590-58-6 4594
46
Menthol Approved Phase 3 2216-51-5 16666
47
Epinephrine Approved, Vet_approved Phase 3 51-43-4 5816
48
Racepinephrine Approved Phase 3 329-65-7 838
49 Hemostatics Phase 3
50 Dermatologic Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 110)
# Name Status NCT ID Phase Drugs
1 Effects of Ilaprazole 20mg on Ulcer Healing Rate and Prevention of Gastrointestinal Bleeding in the Patients Undergone Endoscopic Submucosal Dissection(ESD) for Gastric Adenoma or Early Gastric Cancer. Unknown status NCT02638584 Phase 4 Ilaprazole;Rabeprazole
2 Does Early Re-administration of Aspirin/Clopidogrel Increase the Risk of Bleeding From Artificial Ulcer After EMR or ESD? Unknown status NCT01621451 Phase 4 aspirin and/or clopidogrel;aspirin and/or clopidogrel
3 Efficacy of an Ecabet Sodium and Proton Pump Inhibitor (PPI) Combination Therapy in the Treatment of Iatrogenic Ulcer After Endoscopic Submucosal Dissection: A Prospective Randomized Controlled Trial Unknown status NCT01308177 Phase 4 Ecabet
4 Helicobacter Pylori Eradication Rates of Concomitant Therapy and Tailored Therapy Based on 23S Ribosomal RNA Point Mutations Associated With Clarithromycin Resistance: A Multicenter Prospective Randomized Study Unknown status NCT03130452 Phase 4 Lansoprazole 30mg;Amoxicillin 1.0g Tab;Clarithromycin 500mg;Metronidazole 500 mg
5 The Effect of Perioperative Intravenous Magnesium on Pain After Endoscopic Submucosal Dissection for Gastric Neoplasm: Prospective Randomized Double-blind Placebo Controlled Study Completed NCT02235246 Phase 4 Magnesium Sulfate;Normal saline
6 Effects of Preoperative Administration of Oral Rabeprazole on the Prevention of Ulcer Bleeding Following Endoscopic Mucosal Resection(EMR): Prospective, Randomized, Placebo-controlled, Comparative Study Completed NCT00844675 Phase 4 rabeprazole;placebo
7 Efficacy of Bispectral Index Monitoring for Midazolam and Meperidine Induced Sedation During Endoscopic Submucosal Dissection Unknown status NCT01157598 Phase 3
8 Morbidity and Mortality of Laparoscopy-assisted and Open Distal Gastrectomy for Gastric Cancer in the Elderly Patients: A Randomized Controlled Trial Unknown status NCT02246153 Phase 3
9 Multicenter Study on Comparison of Long-term Outcome Between Laparoscopic and Open Distal Subtotal Gastrectomy With D2 Lymphadenectomy for Locally Advanced Gastric Cancer Unknown status NCT01609309 Phase 3
10 Effect of Helicobacter Pylori Eradication on the New Tumor Development After Endoscopic Resection of Gastric Tumors Completed NCT01510730 Phase 3 eradication treatment of Helicobacter pylori infection
11 Phase III Placebo-controlled Study of NPO-11 in Patients Undergoing Therapeutic Upper Gastrointestinal Endoscopy (Randomized, Double-blind, Parallel-assignment, Placebo-controlled Study) Completed NCT01411176 Phase 3 Menthol;Placebo
12 Prospective Randomized Trial of Laparoscopy-assisted Distal Gastrectomy (LADG) Versus Open Distal Gastrectomy (ODG) in Patients With Early Gastric Cancer (EGC) Completed NCT00546468 Phase 3
13 Multicenter Randomized Controlled Trial Comparing Laparoscopic Pylorus Preserving Gastrectomy Versus Laparoscopic Distal Gastrectomy for the Middle Third Early Gastric Cancer (KLASS-04) Recruiting NCT02595086 Phase 3
14 Prospective Multicenter Study on Laparoscopic Gastric Cancer Surgery Compared With Open Surgery for Locally Advanced Gastric Cancer Recruiting NCT02748551 Phase 3
15 Multicenter Randomized Controlled Trial of Gastric Endoscopic Submucosal Dissection With or Without Epineprhine Added Solution Recruiting NCT04032119 Phase 3 Epinephrine
16 Multicenter Phase III Trial of Laparoscopic Sentinel Node Biopsy and Stomach Preserving Surgery in Early Gastric Cancer Active, not recruiting NCT01804998 Phase 3
17 Phase III Study on Comparison for Bile Reflux and Gastric Stasis in Patients With Gastric Cancer After Distal Gastrectomy Withdrawn NCT00622804 Phase 3
18 A Phase II Study of Robot Assisted Distal Gastrectomy With Nodal Dissection for Clinical Stage Ia Gastric Cancer Unknown status NCT01504997 Phase 2
19 The Effect of Uncut Roux-en-Y Gastrojejunostomy on Quality of Life After Laparoscopic Distal Gastrectomy for Early Gastric Cancer Patients Unknown status NCT02644148 Phase 2
20 Prospective Multi-center Study of Laparoscopy-assisted Total Gastrectomy for Clinical Stage I Gastric Cancer (KLASS-03) Unknown status NCT01584336 Phase 2
21 Laparoscopic Gastrectomy for Advanced Gastric Cancer Completed NCT01441336 Phase 2
22 Laparoscopic Sentinel Node Navigation Surgery for Gastric Cancer Completed NCT01441310 Phase 2
23 The Safety and Feasibility of Reduced Port Robotic Distal Gastrectomy Using Single-site for Surgical Treatment of Early Gastric Cancer Completed NCT02347956 Phase 1, Phase 2
24 A Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Laparoscopic-assisted Gastrectomy in Early Gastric Cancer Patients Completed NCT02522598 Phase 2 VVZ-149 injections;Placebo
25 A Phase-II Clinical Trial of Laparoscopy-Assisted Distal Gastrectomy With D2 Lymph Node Dissection for Gastric Cancer Completed NCT01163812 Phase 2
26 Randomized Phase II Study of FOLFOX Followed by FOLFIRI or Reverse Sequence Treatment in Patients With Advanced or Relapsed Gastric Cancer Completed NCT01138904 Phase 2 irinotecan, oxaliplatin;oxaliplatin, irinotecan
27 A Study to Assess Near Infrared Laparoscopy With Indocyanine Green (ICG) for Intraoperative Lymphatic Imaging and Sentinel Lymph Node Identification During Standard Surgical Resection for Colonic Cancer Completed NCT01662752 Phase 2 Indocyanine green
28 Non-exposure Simple Suturing Endoscopic Full-Thickness Resection (NESS-EFTR) With Laparoscopic Sentinel Lymph Node Navigation for EGC (Senorita3-phase 2) Recruiting NCT03837301 Phase 2
29 Preoperative S-1 Plus Cisplatin-based Chemoradiotherapy for Locally Advanced Resectable Gastric Adenocarcinoma : Randomized, Phase II Trial Recruiting NCT03814759 Phase 2 TS-1 + cisplatin
30 Laparoscopic Versus Open Gastrectomy for Elderly Local Advanced Gastric Cancer Patients: a Phase II Randomized Parallel Controlled Trial Recruiting NCT03564834 Phase 2
31 Prospective Study of Endoscopic Ultrasonographic Staging and Conventional Endoscopic Staging for Depth of Invasion and Endoscopic Tumor Size Estimation for Early Gastric Cancer Unknown status NCT01832246
32 Pilot Study of Non-exposure Simple Suturing EFTR (NESS-EFTR) With Sentinel Lymph Node Navigation for Early Gastric Cancer (Senorita3-pilot) Unknown status NCT03216174
33 Endoscopic Submucosal Dissection Combine With Laparoscopic Regional Lymph Node Dissection:a New Therapy for Early Gastric Cancer Unknown status NCT02325999 Early Phase 1
34 Gastric Cancer Screening and Alarm Symptoms in Early Gastric Cancer Unknown status NCT01659632
35 The Feasible Research of Infrared Endoscope to Diagnose Early Gastric Cancer and Evaluate the Invasive Depth of Tumors Unknown status NCT02710838
36 Long-term Follow-up After Endoscopic Submucosal Dissection for Early Gastric Cancer Unknown status NCT01132469
37 Difference in H. Pylori Infection Rate of EGC Patients Before and After Endoscopic Resection Unknown status NCT02090062
38 Standardization of D2 Lymphadenectomy and Surgical Quality Control for KLASS-02 Trial: KLASS-02-QC Unknown status NCT01283893
39 Clinical Study for the Impact of Bio-absorbable Felt (NEOVEIL®) With Fibrin Sealant on Removal of Drainage Tube After Minimally Invasive Gastrectomy for Gastric Cancer: Multicenter Prospective Randomized Comparison Study Unknown status NCT01742806
40 Probe-based Confocal Laser Endomicroscopy for the Diagnosis of Gastric Intestinal Metaplasia,Intraepithelial Neoplasia,and Carcinoma:A Multicenter,Randomized,Controlled Trial Unknown status NCT02515721
41 Comparison of Proton Pump Inhibitor and H2 Receptor Blocker on Prevention of Bleeding From Iatrogenic Ulcer After Endoscopic Submucosal Dissection for Gastric Neoplasms: A Prospective Randomized Controlled Trial Unknown status NCT01179724 high dose proton pump inhibitor;H2RB
42 An Educational Intervention, the First Step of the Train the Trainer (TTT) Plan, to Improve the Young Endoscopist's Ability to Find the Early Gastric Cancer:Prospective Study With Historical Control Unknown status NCT02385578
43 The Learning Curve of Probe-based Confocal Laser Endomicroscopy (pCLE) Images Interpretation in Gastric Intestinal Metaplasia(GIM) Unknown status NCT01491724
44 Comparisons Between Isoperistaltic and Antiperistaltic Gastrojejunostomy in Laparoscopic Distal Gastrectomy, Randomized Prospective Pilot Study Unknown status NCT02837874
45 Development and Validation of a Predictive Model for Early Gastric Cancerous Lesions Under Endoscopic Observation Unknown status NCT02968069
46 Pilot Trial on Efficacy of Single Dose Perioperative Intravenous Dexamethasone for Pain Relief After Endoscopic Submucosal Dissection Unknown status NCT02037399 intravenous dexamethasone;intravenous normal saline
47 Laparoscopic Reinforcement Suture (LARS) on Staple-line of Duodenal Stump Using Barbed Suture in Laparoscopic Gastrectomy for Gastric Cancer: A Prospective Single Arm Phase II Study Unknown status NCT03085199
48 The Effect and Mechanism of Improving Diabetes by Reconstruction Methods in Gastric Cancer Patients With DM Who Receive Surgical Treatment Unknown status NCT01375738
49 Serum Cholesterol and Gastric Neoplasm: Nested Case-control Study Unknown status NCT02041312
50 Screening and Triage Test for Early Detection of Gastric Cancer Unknown status NCT01774266

Search NIH Clinical Center for Microinvasive Gastric Cancer

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Genetic Tests for Microinvasive Gastric Cancer

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Anatomical Context for Microinvasive Gastric Cancer

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MalaCards organs/tissues related to Microinvasive Gastric Cancer:

40
Lymph Node, Colon, Liver, Bone, Breast, Thyroid, Testes
Sources

Publications for Microinvasive Gastric Cancer

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Articles related to Microinvasive Gastric Cancer:

(show top 50) (show all 4524)
# Title Authors PMID Year
1
Vascular endothelial growth factor-C and -D expression correlates with lymph node micrometastasis in pN0 early gastric cancer. 54 61
19117016 2009
2
Histopathological predictor for regional lymph node metastasis in gastric cancer. 54 61
19104832 2009
3
Comparison of the validity of three biomarkers for gastric cancer screening: carcinoembryonic antigen, pepsinogens, and high sensitive C-reactive protein. 54 61
18648315 2009
4
Cyclooxygenase-2 mediated regulation of E-cadherin occurs in conventional but not early-onset gastric cancer cell lines. 54 61
19940363 2009
5
[Expression of epithelial cadherin in early gastric cancer and its correlation to lymph node micrometastasis and clinicopathologic features]. 54 61
17672949 2007
6
[Clinicopathological and biological features of micrometastasis in early gastric cancers]. 54 61
17571311 2007
7
[Effect of surgical manipulation on the dissemination of cancer cells into peripheral blood in patients with gastric cancer and its risk factor analysis]. 54 61
17520381 2007
8
Screening of atrophic gastritis and gastric cancer by serum pepsinogen, gastrin-17 and Helicobacter pylori immunoglobulin G antibodies. 54 61
17261130 2007
9
Detection of lymph node micrometastasis in pN0 early gastric cancer: efficacy of duplex RT-PCR with MUC2 and TFF1 in mucosal cancer. 54 61
16820924 2006
10
Histologic and serum risk markers for noncardia early gastric cancer. 54 61
15688378 2005
11
Syndecan-1 and E-cadherin expression in differentiated type of early gastric cancer. 54 61
15902740 2005
12
Circulating level of hepatocyte growth factor as a useful tumor marker in patients with early-stage gastric carcinoma. 54 61
15513361 2004
13
[Expression of beta-catenin and E-cadherin in early gastric cancer: correlation with clinicopathologic parameters]. 54 61
14978364 2004
14
[Studies of promoter methylation status and protein expression of E-cadherin gene in associated progression stages of gastric cancer]. 54 61
12776596 2003
15
Relationship between gastric disease and deletion of cag pathogenicity island genes of Helicobacter pylori in gastric juice. 54 61
12645789 2003
16
The CagA protein of Helicobacter pylori is translocated into epithelial cells and binds to SHP-2 in human gastric mucosa. 54 61
12552462 2003
17
Evaluation of carcinoembryonic antigen mRNA in living, necrotic, and apoptotic gastric cancer cells by reverse transcriptase-polymerase chain reaction. 54 61
14605956 2003
18
Abnormal expression of E-cadherin and beta-catenin may be a molecular marker of submucosal invasion and lymph node metastasis in early gastric cancer. 54 61
11856141 2002
19
BGP expression in gastric biopsies may predict the development of new lesions after local treatment for early gastric cancer. 54 61
12378338 2002
20
BGP expression in gastric epithelium and early gastric cancer. 54 61
12378336 2002
21
Significant correlation between micrometastasis in the lymph nodes and reduced expression of E-cadherin in early gastric cancer. 54 61
11706763 2001
22
[A case of radiologically negative small-cell lung carcinoma successfully detected early by whole-body FDG-PET]. 54 61
11296386 2001
23
Changes in the E-cadherin-catenin complex expression in early and advanced gastric cancers. 54 61
11684825 2001
24
Expression of the E-cadherin/catenin (alpha-, beta-, and gamma-) complex correlates with the macroscopic appearance of early gastric cancer. 54 61
11113859 2000
25
Detection of tumor cell contamination in peripheral blood by RT-PCR in gastrointestinal cancer patients. 54 61
10642939 1999
26
Loss of E-cadherin expression in early gastric cancer. 54 61
10231415 1999
27
[The expression of thymidylate synthase and thymidine phosphorylase in the early-stage of gastric cancer]. 54 61
10065095 1999
28
Cooccurrence of reduced expression of alpha-catenin and overexpression of p53 is a predictor of lymph node metastasis in early gastric cancer. 54 61
10461060 1999
29
The expression of cadherin-catenin complex in association with the clinicopathologic features of early gastric cancer. 54 61
9681606 1998
30
High prevalence of the CagA-positive Helicobacter pylori strains in Japanese asymptomatic patients and gastric cancer patients. 54 61
9175208 1997
31
Single-cell mutation analysis of tumors from stained histologic slides. 54 61
8973475 1996
32
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas. 54 61
8641546 1996
33
Does Helicobacter pylori Eradication Reduce the Incidence of Metachronous Gastric Cancer After Curative Endoscopic Resection of Early Gastric Cancer: A Systematic Review and Meta-Analysis. 61
30829904 2020
34
The Suggestion of Revised Criteria for Endoscopic Resection of Differentiated-Type Submucosal Gastric Cancer. 61
31828690 2020
35
Indocyanine green fluorescence lymphography during gastrectomy after initial endoscopic submucosal dissection for early gastric cancer. 61
32031248 2020
36
Plasma proteomics-based identification of novel biomarkers in early gastric cancer. 61
31765635 2020
37
Risk Factors for Post-gastric Endoscopic Submucosal Dissection Bleeding with a Special Emphasis on Anticoagulant Therapy. 61
31392471 2020
38
DERL3 functions as a tumor suppressor in gastric cancer. 61
31862624 2020
39
Endoscopic acanthosis nigricans appearance: a novel specific marker for diagnosis of low-grade intraepithelial neoplasia. 61
32020670 2020
40
Statins and metachronous recurrence after endoscopic resection of early gastric cancer: a nationwide Korean cohort study. 61
31980964 2020
41
Convolutional neural network for the diagnosis of early gastric cancer based on magnifying narrow band imaging. 61
31332619 2020
42
Numerous lymph node metastases in early gastric cancer without preoperatively enlarged lymph nodes: a case report. 61
32002705 2020
43
Endoscopic Submucosal Dissection of Early Gastric Cancer with Mixed-Type Histology: A Systematic Review. 61
31367880 2020
44
Early Gastric Cancer with Mixed-Type Histology: A Mixed Bag or Pure Evil? 61
31732906 2020
45
Community-Based Pilot Study of a Screening Program for Gastric Cancer in a Chinese Population. 61
31796467 2020
46
Margin diagnosis for endoscopic submucosal dissection of early gastric cancer using multiphoton microscopy. 61
30972623 2020
47
The Color Difference between Differentiated Early Gastric Cancer and Suspicious Mucosal Areas on Linked Color Imaging. 61
31722352 2020
48
Endoscopic selective muscular dissection for clinical submucosal invasive early gastric cancer. 61
31732984 2020
49
Poor survival after resection of early gastric cancer: extremes of survivorship analysis reveal distinct genomic profile. 61
31763684 2020
50
History and future perspectives in Japanese guidelines for endoscopic resection of early gastric cancer. 61
31529716 2020
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Variations for Microinvasive Gastric Cancer

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Expression for Microinvasive Gastric Cancer

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Search GEO for disease gene expression data for Microinvasive Gastric Cancer.
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Pathways for Microinvasive Gastric Cancer

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Pathways related to Microinvasive Gastric Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Gastric acid production 1
9.8 MUC6 GAST
2
Secretion of Hydrochloric Acid in Parietal Cells 1
9.32 GAST ATP4A
Sources

GO Terms for Microinvasive Gastric Cancer

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Cellular components related to Microinvasive Gastric Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.28 VEGFC TFF2 SERPINB3 S100A8 MUC6 MUC5AC

Biological processes related to Microinvasive Gastric Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 maintenance of gastrointestinal epithelium GO:0030277 9.32 TFF2 MUC6
2 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.26 ATP4A ATP12A
3 sodium ion export across plasma membrane GO:0036376 9.16 ATP4A ATP12A
4 cellular potassium ion homeostasis GO:0030007 8.96 ATP4A ATP12A
5 autocrine signaling GO:0035425 8.62 SERPINB3 S100A8

Molecular functions related to Microinvasive Gastric Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A
Sources

Sources for Microinvasive Gastric Cancer

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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