Microinvasive Gastric Cancer disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: MCR011 MIFTS: 41	Microinvasive Gastric Cancer Categories: Cancer diseases, Gastrointestinal diseases	Data Licensing For inquiries, contact: [email protected]
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Aliases & Classifications for Microinvasive Gastric Cancer

MalaCards integrated aliases for Microinvasive Gastric Cancer:

Name: Microinvasive Gastric Cancer ¹¹ ¹⁴

Early Gastric Cancer ¹¹ ⁵³ ¹⁴ ⁷¹

Surface Gastric Cancer ¹¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:10541

NCIt ⁴⁹ C27131

SNOMED-CT ⁶⁸ 276809004

UMLS ⁷¹ C0349530

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Summaries for Microinvasive Gastric Cancer

MalaCards based summary: Microinvasive Gastric Cancer, also known as early gastric cancer, is related to adenocarcinoma and gastric ulcer, and has symptoms including abdominal pain and dyspepsia. An important gene associated with Microinvasive Gastric Cancer is TDRG1 (Testis Development Related 1), and among its related pathways/superpathways is E-cadherin signaling in keratinocytes. The drugs Pantoprazole and Acetylsalicylic acid have been mentioned in the context of this disorder. Affiliated tissues include lymph node, bone marrow and colon, and related phenotypes are neoplasm and digestive/alimentary

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Related Diseases for Microinvasive Gastric Cancer

Diseases related to Microinvasive Gastric Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 511)

#	Related Disease	Score	Top Affiliating Genes
1	adenocarcinoma	31.4	VEGFC MLH1 CEACAM5 CDX2 CDH1
2	gastric ulcer	31.3	S100A8 GAST ATP12A
3	diffuse gastric cancer	31.3	S100A8 PDPN MLH1 CTNNA1 CDH1
4	adenoma	31.2	MUC6 MLH1 CDX2 CDH1
5	gastric adenocarcinoma	31.2	S100A8 MLH1 GAST CEACAM5 CDX2 CDH1
6	gastritis	31.2	S100A8 MUC6 MIR196A1 GAST CDX2 CDH1
7	tubular adenocarcinoma	31.2	MUC6 CTNNA1 CEACAM5 CDX2 CDH1
8	signet ring cell adenocarcinoma	31.2	PDPN MUC6 MLH1 CEACAM5 CDX2 CDH1
9	peptic esophagitis	31.1	S100A8 GAST CDX2 ATP4A ATP12A
10	appendix adenocarcinoma	31.1	CEACAM5 CDX2
11	peptic ulcer disease	31.0	S100A8 GAST ATP4A ATP12A
12	postgastrectomy syndrome	30.9	ATP4A ATP12A
13	pernicious anemia	30.9	GAST ATP4A ATP12A
14	atrophic gastritis	30.8	S100A8 MIR20A MIR196A1 GAST CDX2 ATP4A
15	mucinous adenocarcinoma	30.8	MUC6 MLH1 CEACAM5 CDX2
16	colonic benign neoplasm	30.8	MLH1 GAST CEACAM5 CDX2 CDH1
17	krukenberg carcinoma	30.7	CEACAM5 CDX2
18	lymphoma, mucosa-associated lymphoid type	30.7	S100A8 GAST ATP4A ATP12A
19	linitis plastica	30.7	CTNNA1 CEACAM5 CDX2 CDH1
20	vitamin b12 deficiency	30.7	GAST ATP4A ATP12A
21	gastric cancer	30.6	XIST VEGFC TDRG1 S100A8 PSG2 PDPN
22	bile reflux	30.6	S100A8 GAST CDX2 ATP4A ATP12A
23	cholecystitis	30.5	S100A8 MUC6 CDH1
24	hernia, hiatus	30.5	GAST ATP4A ATP12A
25	gastric lymphoma	30.5	S100A8 ATP4A ATP12A
26	cardia cancer	30.5	S100A8 GAST ATP4A ATP12A
27	gastroesophageal reflux	30.5	S100A8 GAST CDX2 ATP4A ATP12A
28	gastric antral vascular ectasia	30.4	GAST ATP4A ATP12A
29	marginal zone b-cell lymphoma	30.4	S100A8 ATP4A ATP12A
30	adenoid squamous cell carcinoma	30.3	CEACAM5 CDH1
31	transverse colon cancer	30.3	MLH1 CEACAM5
32	ascending colon cancer	30.3	MLH1 CEACAM5 CDX2
33	adenocarcinoma in situ	30.3	PDPN MUC6 CEACAM5 CDX2
34	colorectal adenoma	30.2	MLH1 CEACAM5 CDH1
35	gastrointestinal system disease	30.2	S100A8 MIR20A MIR196A1 MIR15B GAST
36	splenic artery aneurysm	30.2	ATP4A ATP12A
37	squamous cell carcinoma	30.2	VEGFC PDPN CEACAM5 CDH1 BCYRN1
38	cholangiocarcinoma	30.2	VEGFC CTNNA1 CEACAM5 CDX2 CDH1
39	autoimmune gastritis	30.2	S100A8 MUC6 GAST ATP4A ATP12A
40	lymphocytic gastritis	30.2	GAST ATP4A ATP12A
41	mediastinitis	30.2	ATP4A ATP12A
42	gastric neuroendocrine neoplasm	30.2	GAST ATP4A ATP12A
43	duodenogastric reflux	30.2	GAST ATP4A ATP12A
44	choledocholithiasis	30.2	CEACAM5 ATP4A ATP12A
45	rectal benign neoplasm	30.1	MLH1 MIR20A CEACAM5 CDX2
46	pseudomyxoma peritonei	30.1	MUC6 CEACAM5 CDX2 CDH1
47	gallbladder disease	30.1	PDPN MIR196A1 CEACAM5 CDH1
48	nutritional deficiency disease	30.1	GAST ATP4A ATP12A
49	villous adenoma	30.1	MUC6 MLH1 CEACAM5 CDX2
50	intestinal obstruction	30.0	CEACAM5 CDX2 ATP4A ATP12A

Graphical network of the top 20 diseases related to Microinvasive Gastric Cancer:

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Symptoms & Phenotypes for Microinvasive Gastric Cancer

UMLS symptoms related to Microinvasive Gastric Cancer:

abdominal pain; dyspepsia

MGI Mouse Phenotypes related to Microinvasive Gastric Cancer:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	neoplasm	MP:0002006	9.5	ATP4A CDH1 CDX2 CEACAM5 CTNNA1 GAST
2	digestive/alimentary	MP:0005381	9.23	ATP12A ATP4A CDH1 CDX2 CEACAM5 GAST

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Drugs & Therapeutics for Microinvasive Gastric Cancer

Drugs for Microinvasive Gastric Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 89)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Pantoprazole

Approved

Phase 4

102625-70-7, 138786-67-1

4679

Acetylsalicylic acid

Approved, Vet_approved

Phase 4

50-78-2

2244

Clopidogrel

Approved

Phase 4

120202-66-6, 113665-84-2

60606

Rabeprazole

Approved, Investigational

Phase 4

117976-89-3, 117976-90-6

5029

Anti-Inflammatory Agents

Phase 4

Analgesics, Non-Narcotic

Phase 4

Antirheumatic Agents

Phase 4

Fibrinolytic Agents

Phase 4

Antipyretics

Phase 4

Purinergic P2Y Receptor Antagonists

Phase 4

Cyclooxygenase Inhibitors

Phase 4

Platelet Aggregation Inhibitors

Phase 4

Anti-Inflammatory Agents, Non-Steroidal

Phase 4

Proton Pump Inhibitors

Phase 4

Gastrointestinal Agents

Phase 4

Anti-Ulcer Agents

Phase 4

Antacids

Phase 4

Racepinephrine

Approved, Vet_approved

Phase 3

51-43-4, 329-65-7

838 5816

Amoxicillin

Approved, Vet_approved

Phase 3

26787-78-0

33613

Esomeprazole

Approved, Investigational, Vet_approved

Phase 3

73590-58-6, 119141-88-7

9568614 4594

Clarithromycin

Approved

Phase 3

81103-11-9

84029

Anesthetics

Phase 3

Hemostatics

Phase 3

Adrenergic alpha-Agonists

Phase 3

Adrenergic Agonists

Phase 3

Adrenergic Agents

Phase 3

Epinephryl borate

Phase 3

Bronchodilator Agents

Phase 3

Adrenergic beta-Agonists

Phase 3

Anti-Asthmatic Agents

Phase 3

Vasoconstrictor Agents

Phase 3

Respiratory System Agents

Phase 3

Mydriatics

Phase 3

Sympathomimetics

Phase 3

Anti-Bacterial Agents

Phase 3

Anti-Infective Agents

Phase 3

Antibiotics, Antitubercular

Phase 3

Cytochrome P-450 Enzyme Inhibitors

Phase 3

Cytochrome P-450 CYP3A Inhibitors

Phase 3

Analgesics

Phase 2

Dexlansoprazole

Approved, Investigational

138530-94-6

9578005

Dexamethasone acetate

Approved, Investigational, Vet_approved

1177-87-3

3680

Lansoprazole

Approved, Investigational

103577-45-3

3883

Dexamethasone

Approved, Investigational, Vet_approved

50-02-2

3003 5743

Sucralfate

Approved

54182-58-0

Methylene blue

Approved, Investigational

61-73-4

6099

Dexmedetomidine

Approved, Experimental, Vet_approved

86347-14-0, 113775-47-6

68602 5311068

Remifentanil

Approved

132875-61-7

60815

Propofol

Approved, Investigational, Vet_approved

2078-54-8

4943

Lidocaine

Approved, Vet_approved

137-58-6

3676

Interventional clinical trials:

(show top 50) (show all 76)

#	Name	Status	NCT ID	Phase	Drugs
1	Does Early Re-administration of Aspirin/Clopidogrel Increase the Risk of Bleeding From Artificial Ulcer After EMR or ESD?	Unknown status	NCT01621451	Phase 4	aspirin and/or clopidogrel
2	Effects of Ilaprazole 20mg on Ulcer Healing Rate and Prevention of Gastrointestinal Bleeding in the Patients Undergone Endoscopic Submucosal Dissection(ESD) for Gastric Adenoma or Early Gastric Cancer.	Completed	NCT02638584	Phase 4	Ilaprazole;Rabeprazole
3	Magnetic-controlled Capsule Endoscopy vs. Gastroscopy for Detection of Gastric Diseases: A Prospective Self-controlled Comparative Multicenter Trial	Completed	NCT02219529	Phase 3
4	Prospective Randomized Trial of Laparoscopy-assisted Distal Gastrectomy (LADG) Versus Open Distal Gastrectomy (ODG) in Patients With Early Gastric Cancer (EGC)	Completed	NCT00546468	Phase 3
5	Multicenter Randomized Controlled Trial of Gastric Endoscopic Submucosal Dissection With or Without Epineprhine Added Solution	Recruiting	NCT04032119	Phase 3	Epinephrine
6	Effect of Helicobacter Pylori Eradication on Glandular Atrophy and Metachronous Cancer in Patients Undergoing Endoscopic Mucosal Resection for Gastric Cancer	Active, not recruiting	NCT02407119	Phase 3	7 day H.pylori eradication Omeprazole or Rabeprazole, Clarithromycin, Amoxicillin;Placebo, Omeprazole or Rabeprazole, Clarithromycin
7	Non-exposure Simple Suturing Endoscopic Full-Thickness Resection (NESS-EFTR) With Laparoscopic Sentinel Lymph Node Navigation for EGC (Senorita3-phase 2)	Unknown status	NCT03837301	Phase 2
8	A Phase II Study of Robot Assisted Distal Gastrectomy With Nodal Dissection for Clinical Stage Ia Gastric Cancer	Unknown status	NCT01504997	Phase 2
9	The Effect of Uncut Roux-en-Y Gastrojejunostomy on Quality of Life After Laparoscopic Distal Gastrectomy for Early Gastric Cancer Patients	Unknown status	NCT02644148	Phase 2
10	A Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Laparoscopic-assisted Gastrectomy in Early Gastric Cancer Patients	Completed	NCT02522598	Phase 2	VVZ-149 injections;Placebo
11	The Safety and Feasibility of Reduced Port Robotic Distal Gastrectomy Using Single-site for Surgical Treatment of Early Gastric Cancer	Completed	NCT02347956	Phase 1, Phase 2
12	Prospective Clinical Trials on Clinical Outcomes of Indocyanine Green Tracer Using in Laparoscopic Distal Gastrectomy With Lymph Node Dissection for Early Gastric Cancer	Not yet recruiting	NCT04973475	Phase 2	Indocyanine Green
13	Difference in H. Pylori Infection Rate of EGC Patients Before and After Endoscopic Resection	Unknown status	NCT02090062
14	Comparison of Diagnostic Performance of Medical Monitor and Medical Augmented Reality Glasses in Endoscopy: Observation Study	Unknown status	NCT04083573
15	Pilot Trial on Efficacy of Single Dose Perioperative Intravenous Dexamethasone for Pain Relief After Endoscopic Submucosal Dissection	Unknown status	NCT02037399		intravenous dexamethasone;intravenous normal saline
16	Development and Validation of a Predictive Model for Early Gastric Cancerous Lesions Under Endoscopic Observation	Unknown status	NCT02968069
17	Prospective Study of Endoscopic Ultrasonographic Staging and Conventional Endoscopic Staging for Depth of Invasion and Endoscopic Tumor Size Estimation for Early Gastric Cancer	Unknown status	NCT01832246
18	The Feasible Research of Infrared Endoscope to Diagnose Early Gastric Cancer and Evaluate the Invasive Depth of Tumors	Unknown status	NCT02710838
19	Gastric Cancer Sentinel Lymph Node Sampling: Refining Patient Selection for Organ Sparing Resection of Early Gastric Cancer in a North American Context	Unknown status	NCT03049345		Radioactive Tracers;Methylene Blue 20 MG/ML
20	Endoscopic Submucosal Dissection Combine With Laparoscopic Regional Lymph Node Dissection:a New Therapy for Early Gastric Cancer	Unknown status	NCT02325999	Early Phase 1
21	Pilot Study of Non-exposure Simple Suturing EFTR (NESS-EFTR) With Sentinel Lymph Node Navigation for Early Gastric Cancer (Senorita3-pilot)	Unknown status	NCT03216174
22	A Prospective Randomized Study of Linked Color Imaging and Conventional White Light Imaging in Gastroscopy for the Detection of Gastric Cancer Precursors	Unknown status	NCT03990025
23	Gastric Cancer Screening and Alarm Symptoms in Early Gastric Cancer	Unknown status	NCT01659632
24	Verifying the Specificity of the Method Combining Nomogram and Sentinel Lymph Node in Predicting Lymph Node Metastasis in Early Gastric Cancer Patients: a Prospective, Single Arm, Observational Study	Unknown status	NCT03632746
25	Magnifying Endoscopy With Narrow Band Imaging Versus Endoscopic Ultrasonography for Prediction of Tumor Invasion Depth in Early Gastric Cancer: A Prospective Comparative Study	Unknown status	NCT03546257
26	An Educational Intervention, the First Step of the Train the Trainer (TTT) Plan, to Improve the Young Endoscopist's Ability to Find the Early Gastric Cancer:Prospective Study With Historical Control	Unknown status	NCT02385578
27	Application of Linked Color Imaging（LCI） in Diagnosis of Early Gastric Cancer(EGC): a Multicenter,Prospective, Randomized Controlled Study	Unknown status	NCT03661671
28	Long-term Follow-up After Endoscopic Submucosal Dissection for Early Gastric Cancer	Unknown status	NCT01132469
29	Evaluation of the Diagnostic Ability of White Light Endoscopy and Magnifying Endoscopy With Optical Enhancement System in Early Gastric Cancer and Intraepithelial Neoplasia: a Prospective Randomized Controlled Trial	Unknown status	NCT04411589
30	Laparoscopy-assisted Pylorus-vagus Nerve Preserving Gastrectomy in the Treatment of Early Gastric Cancer: Clinical Outcomes of a Randomised Controlled Trial	Unknown status	NCT02936193
31	Screening and Triage Test for Early Detection of Gastric Cancer	Unknown status	NCT01774266
32	Setting the Shortest Examination Time of Gastroscopy to Improve the Detection Rate of Upper Gastrointestinal Tumors: a Multi-center, Prospective, Controlled Study	Completed	NCT04602299
33	Necessity Assessment of Magnifying Endoscopy With Narrow Band Imaging Targeted Biopsy Compared With Endoscopic Forceps Biopsy From White Light Endoscopy	Completed	NCT02738294
34	A Comparison of Efficacy and Safety During Endoscopic Submucosal Dissection Between Dexmedetomidine-remifentanil and Propofol-remifentanil	Completed	NCT01920113		Dexmedetomidine - remifentanil group;Propofol - remifentanil group
35	Monitored Anesthesia Care With Propofol Plus Remifentanil During Endoscopic Submucosal Dissection: Evaluation of Bispectral Index Monitoring	Completed	NCT01921283		no- BIS sensor attachment
36	Postoperative Pain and Quality of Life After Single-incision Distal Gastrectomy Versus Totally Laparoscopic Distal Gastrectomy for Early Gastric Cancer - a Randomized Controlled Trial	Completed	NCT01938326
37	The Effect of Proton Pump Inhibitor and Polaprezinc Combination Therapy for Healing of Endoscopic Submucosal Dissection-induced Ulcer	Completed	NCT02243618		Polaprezinc;Rebamipide
38	OLGA Stage is More Appropriate in Predicting Early Gastric Cancer Than Endoscopic Gastric Atrophy Classification and OLGIM Stage: A Prospective Study	Completed	NCT02562976
39	The Accuracy of Probe-based Confocal Endomicroscopy Versus Conventional Biopsies for the Diagnosis of Superficial Gastric Neoplasias	Completed	NCT01688687
40	Effect of Gastrectomy and Anastomosis on Chronic Metabolic Disease Such as Diabetes and Hypertension in Early Gastric Cancer Patients	Completed	NCT01643811
41	Effect of Midazolam Premedication on the Satisfaction Levels of Patients After Endoscopic Submucosal Dissection	Completed	NCT02504164		midazolam 0.02mg/kg;No premedication
42	Prospective Randomized Trial Comparing Endoscopic Submucosal Dissection Against Laparoscopic Assisted Gastrectomy for Treatment of Early Gastric Cancer	Completed	NCT03136354
43	Nexium Capsules Specific Clinical Experience Investigation Concerning Helicobacter Pylori Eradication	Completed	NCT01435525
44	Absorption of Anti-tuberculosis Drugs and Its Effect to Treatment Response in Gastrectomized Patients	Completed	NCT01364324		standard first line anti-TB drugs
45	Performance of Endoscopic Submucosal Dissection According to the Sedation Method	Completed	NCT01806753
46	Quality Control Study for Multicenter Phase III Trial of Laparoscopic Sentinel Node Biopsy and Stomach Preserving Surgery in Early Gastric Cancer	Completed	NCT01544413
47	Role of Statin on the Gastric Inflammation in Patients at High Risk of Gastric Cancer	Completed	NCT01813994		Arm1: Statin;Arm2: Placebo
48	Multicenter Phase III Trial of Laparoscopic Sentinel Node Biopsy and Stomach Preserving Surgery in Early Gastric Cancer	Completed	NCT01804998
49	Long-term Outcomes of Endoscopic Submucosal Dissection Versus Gastrectomy for Early Gastric Cancer	Completed	NCT02216110
50	Usefulness of Probe-based Confocal Laser Endo-microscopy in Delineation of Margin of Early Gastric Cancer for Endoscopic Submucosal Dissection	Completed	NCT02189226

Search NIH Clinical Center for Microinvasive Gastric Cancer

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Genetic Tests for Microinvasive Gastric Cancer

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Anatomical Context for Microinvasive Gastric Cancer

Organs/tissues related to Microinvasive Gastric Cancer:

MalaCards : Lymph Node, Bone Marrow, Colon, Liver, Bone, Skeletal Muscle, Spleen

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Publications for Microinvasive Gastric Cancer

Articles related to Microinvasive Gastric Cancer:

(show top 50) (show all 5323)

#	Title	Authors	PMID	Year
1	Vascular endothelial growth factor-C and -D expression correlates with lymph node micrometastasis in pN0 early gastric cancer. ⁵³ ⁶²	Arigami T...Aikou T	19117016	2009
2	Histopathological predictor for regional lymph node metastasis in gastric cancer. ⁵³ ⁶²	Morita H...Ishii T	19104832	2009
3	Cyclooxygenase-2 mediated regulation of E-cadherin occurs in conventional but not early-onset gastric cancer cell lines. ⁵³ ⁶²	Sitarz R...Milne AN	19940363	2009
4	Comparison of the validity of three biomarkers for gastric cancer screening: carcinoembryonic antigen, pepsinogens, and high sensitive C-reactive protein. ⁵³ ⁶²	Chung HW...Lim JB	18648315	2009
5	[Expression of epithelial cadherin in early gastric cancer and its correlation to lymph node micrometastasis and clinicopathologic features]. ⁵³ ⁶²	Liu J...Masahide I	17672949	2007
6	[Clinicopathological and biological features of micrometastasis in early gastric cancers]. ⁵³ ⁶²	Pan WS...Ebihar Y	17571311	2007
7	[Effect of surgical manipulation on the dissemination of cancer cells into peripheral blood in patients with gastric cancer and its risk factor analysis]. ⁵³ ⁶²	Zhang JP...Wu WZ	17520381	2007
8	Screening of atrophic gastritis and gastric cancer by serum pepsinogen, gastrin-17 and Helicobacter pylori immunoglobulin G antibodies. ⁵³ ⁶²	Cao Q...Xiao SD	17261130	2007
9	Detection of lymph node micrometastasis in pN0 early gastric cancer: efficacy of duplex RT-PCR with MUC2 and TFF1 in mucosal cancer. ⁵³ ⁶²	Sonoda H...Tani T	16820924	2006
10	Histologic and serum risk markers for noncardia early gastric cancer. ⁵³ ⁶²	Shiotani A...Graham DY	15688378	2005
11	Syndecan-1 and E-cadherin expression in differentiated type of early gastric cancer. ⁵³ ⁶²	Huang MF...Yang GF	15902740	2005
12	Circulating level of hepatocyte growth factor as a useful tumor marker in patients with early-stage gastric carcinoma. ⁵³ ⁶²	Tanaka K...Kusunoki M	15513361	2004
13	[Expression of beta-catenin and E-cadherin in early gastric cancer: correlation with clinicopathologic parameters]. ⁵³ ⁶²	Song BJ...Chang SH	14978364	2004
14	[Studies of promoter methylation status and protein expression of E-cadherin gene in associated progression stages of gastric cancer]. ⁵³ ⁶²	Zheng ZH...Sun KL	12776596	2003
15	Relationship between gastric disease and deletion of cag pathogenicity island genes of Helicobacter pylori in gastric juice. ⁵³ ⁶²	Kawamura O...Mori M	12645789	2003
16	Evaluation of carcinoembryonic antigen mRNA in living, necrotic, and apoptotic gastric cancer cells by reverse transcriptase-polymerase chain reaction. ⁵³ ⁶²	Kojima N...Saji S	14605956	2003
17	The CagA protein of Helicobacter pylori is translocated into epithelial cells and binds to SHP-2 in human gastric mucosa. ⁵³ ⁶²	Yamazaki S...Azuma T	12552462	2003
18	Abnormal expression of E-cadherin and beta-catenin may be a molecular marker of submucosal invasion and lymph node metastasis in early gastric cancer. ⁵³ ⁶²	Tanaka M...Miyazaki K	11856141	2002
19	BGP expression in gastric biopsies may predict the development of new lesions after local treatment for early gastric cancer. ⁵³ ⁶²	Shimada S...Ogawa M	12378338	2002
20	BGP expression in gastric epithelium and early gastric cancer. ⁵³ ⁶²	Barbosa AJ...Castro LP	12378336	2002
21	Significant correlation between micrometastasis in the lymph nodes and reduced expression of E-cadherin in early gastric cancer. ⁵³ ⁶²	Cai J...Kaibara N	11706763	2001
22	[A case of radiologically negative small-cell lung carcinoma successfully detected early by whole-body FDG-PET]. ⁵³ ⁶²	Demura Y...Yonekura Y	11296386	2001
23	Changes in the E-cadherin-catenin complex expression in early and advanced gastric cancers. ⁵³ ⁶²	Joo YE...Kim SJ	11684825	2001
24	Expression of the E-cadherin/catenin (alpha-, beta-, and gamma-) complex correlates with the macroscopic appearance of early gastric cancer. ⁵³ ⁶²	Ohene-Abuakwa Y...Pignatelli M	11113859	2000
25	Detection of tumor cell contamination in peripheral blood by RT-PCR in gastrointestinal cancer patients. ⁵³ ⁶²	Noh YH...Ahn MJ	10642939	1999
26	Loss of E-cadherin expression in early gastric cancer. ⁵³ ⁶²	Blok P...Tytgat GN	10231415	1999
27	[The expression of thymidylate synthase and thymidine phosphorylase in the early-stage of gastric cancer]. ⁵³ ⁶²	Suda Y...Tanaka Y	10065095	1999
28	Cooccurrence of reduced expression of alpha-catenin and overexpression of p53 is a predictor of lymph node metastasis in early gastric cancer. ⁵³ ⁶²	Xiangming C...Aikou T	10461060	1999
29	The expression of cadherin-catenin complex in association with the clinicopathologic features of early gastric cancer. ⁵³ ⁶²	Xiangming C...Aikou T	9681606	1998
30	High prevalence of the CagA-positive Helicobacter pylori strains in Japanese asymptomatic patients and gastric cancer patients. ⁵³ ⁶²	Shimoyama T...Munakata A	9175208	1997
31	Single-cell mutation analysis of tumors from stained histologic slides. ⁵³ ⁶²	Becker I...Hofler H	8973475	1996
32	Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas. ⁵³ ⁶²	Anzai H...Fidler IJ	8641546	1996
33	Red blood cell distribution width as a novel marker for predicting bleeding after endoscopic resection for early gastric cancer. ⁶²	Yumemi T...Nakase H	36247311	2023
34	Usefulness of third-generation narrow band imaging and texture and color enhancement imaging in improving visibility of superficial early gastric cancer: A study using color difference. ⁶²	Kawasaki A...Doyama H	36439990	2023
35	Mixed Histologic Type is a Risk Factor for Lymph Node Metastasis in Submucosal Invasive Early Gastric Cancer. ⁶²	Sun F...Wang M	36306586	2023
36	Endoscopic Submucosal Dissection in the Stomach and Duodenum: Techniques, Indications, and Outcomes. ⁶²	Al Ghamdi SS...Ngamruengphong S	36375887	2023
37	Gastric Emptying is Accelerated in Patients With Gastric Tube Reconstruction Following Laparoscopic Proximal Gastrectomy. ⁶²	Toyomasu Y...Ishida H	36223321	2022
38	Artificial intelligence for diagnosing gastric lesions under white-light endoscopy. ⁶²	Yuan XL...Hu B	35879572	2022
39	The impact of sarcopenia on short- and long-term outcomes of endoscopic submucosal dissection for early gastric cancer. ⁶²	Hisada H...Fujishiro M	36129538	2022
40	Higher prevalence of LAP+ (Latency TGFβ-Associated Peptide) T cells at the tissue level in patients with early gastric cancer. ⁶²	Aguinaga-Barrilero A...Martin-Villa JM	36332356	2022
41	Automatic captioning of early gastric cancer using magnification endoscopy with narrow-band imaging. ⁶²	Gong L...Zhou P	35917877	2022
42	A case of early gastric cancer resembling a subepithelial lesion diagnosed by endoscopic ultrasound-guided fine needle aspiration. ⁶²	Imamura S...Nishida J	36198987	2022
43	Diagnostic accuracy of linked colour imaging versus white light imaging for early gastric cancers: a prospective, multicentre, randomized controlled trial study. ⁶²	Min M...Liu Y	36411585	2022
44	A rare helicobacter pylori infection-negative early gastric cancer in a young man with primary hypertrophic osteoarthropathy. ⁶²	Dong Z...Wan X	35081636	2022
45	Linked color imaging-based endoscopic grading of gastric intestinal metaplasia and histological gastritis staging in the assessment of gastric cancer risk. ⁶²	Zheng J...Wang W	35701150	2022
46	Gel immersion endoscopic mucosal resection for early gastric cancer near the pyloric ring. ⁶²	Miura K...Nakase H	35120390	2022
47	Applicability of endoscopic submucosal dissection for patients with early gastric cancer beyond the expanded indication for endoscopic submucosal dissection. ⁶²	Song JH...Hyung WJ	35546209	2022
48	Clinical significance of the number of retrieved lymph nodes in early gastric cancer with submucosal invasion. ⁶²	Kim DH...Lee TG	36401371	2022
49	Linked color imaging improves identification of early gastric cancer lesions by expert and non-expert endoscopists. ⁶²	Fockens K...Bergman J	35508665	2022
50	Epstein-Barr virus detection in endoscopic submucosal dissection-proven early gastric cancer with mixed-type histology. ⁶²	Yanai H...Nishikawa J	36421012	2022

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Genes for Microinvasive Gastric Cancer

Genes related to Microinvasive Gastric Cancer (0 elite genes):

(show all 29)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	TDRG1	Testis Development Related 1	RNA Gene	154.16	Experimental evidence: Expression ³⁷ DISEASES inferred ¹⁴	29039538
2	RRP1B	Ribosomal RNA Processing 1B	Protein Coding	153.76	Experimental evidence: Expression ³⁷ DISEASES inferred ¹⁴	29039538
3	BCYRN1	Brain Cytoplasmic RNA 1	RNA Gene	150	Experimental evidence: Expression ³⁷	29039538
4	XIST	X Inactive Specific Transcript	RNA Gene	150	Experimental evidence: Expression ³⁷	29039538
5	CDH1	Cadherin 1	Protein Coding	13.29	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	11113859 17672949 14978364 (more) 11706763 11856141 9681606 15141383 8973475 17571311 10231415 19940363 8641546 12776596 15902740 11684825
6	CDX2	Caudal Type Homeobox 2	Protein Coding	13.18	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	15144397 19820687 16803685
7	CEACAM5	CEA Cell Adhesion Molecule 5	Protein Coding	12.11	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	14605956 9660027 10642939
8	GAST	Gastrin	Protein Coding	11.43	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	15688378 17261130
9	S100A8	S100 Calcium Binding Protein A8	Protein Coding	11.02	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	9175208 12552462 12645789
10	MLH1	MutL Homolog 1	Protein Coding	9.96	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	11313962
11	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	8.69	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	19117016 12604720 19104832
12	MIR196A1	MicroRNA 196a-1	RNA Gene	8.31	DISEASES inferred ¹⁴ ¹⁴
13	MIR20A	MicroRNA 20a	RNA Gene	7.93	DISEASES inferred ¹⁴ ¹⁴
14	PDPN	Podoplanin	Protein Coding	7.44	DISEASES inferred ¹⁴
15	CTNNA1	Catenin Alpha 1	Protein Coding	7.33	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	10461060 9681606
16	ATP4A	ATPase H+/K+ Transporting Subunit Alpha	Protein Coding	7.29	DISEASES inferred ¹⁴
17	ATP12A	ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit	Protein Coding	7.28	DISEASES inferred ¹⁴
18	MIR15B	MicroRNA 15b	RNA Gene	6.99	DISEASES inferred ¹⁴ ¹⁴
19	MUC6	Mucin 6, Oligomeric Mucus/Gel-Forming	Protein Coding	6.64	DISEASES inferred ¹⁴
20	PSG2	Pregnancy Specific Beta-1-Glycoprotein 2	Protein Coding	6.35	Novoseek inferred ⁵³	15513361 11296386 17520381 (more) 18648315
21	MIR129-1	MicroRNA 129-1	RNA Gene	6.35	DISEASES inferred ¹⁴ ¹⁴
22	MUC5AC	Mucin 5AC, Oligomeric Mucus/Gel-Forming	Protein Coding	6.26	DISEASES inferred ¹⁴
23	MIR199A1	MicroRNA 199a-1	RNA Gene	6.15	DISEASES inferred ¹⁴ ¹⁴
24	TP53	Tumor Protein P53	Protein Coding	6.11	DISEASES inferred ¹⁴
25	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	6.07	DISEASES inferred ¹⁴
26	TFF2	Trefoil Factor 2	Protein Coding	5.99	DISEASES inferred ¹⁴
27	MIR125A	MicroRNA 125a	RNA Gene	5.99	DISEASES inferred ¹⁴ ¹⁴
28	CHKA	Choline Kinase Alpha	Protein Coding	5.89	Novoseek inferred ⁵³	17672949 11706763
29	AFP	Alpha Fetoprotein	Protein Coding	5.85	DISEASES inferred ¹⁴

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Variations for Microinvasive Gastric Cancer

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Expression for Microinvasive Gastric Cancer

Search GEO for disease gene expression data for Microinvasive Gastric Cancer.

Sources

Pathways for Microinvasive Gastric Cancer

Pathways related to Microinvasive Gastric Cancer according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	E-cadherin signaling in keratinocytes ⁶¹	9.88	CTNNA1 CDH1

Sources

GO Terms for Microinvasive Gastric Cancer

Cellular components related to Microinvasive Gastric Cancer according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	flotillin complex	GO:0016600	8.92	CTNNA1 CDH1

Biological processes related to Microinvasive Gastric Cancer according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cellular response to indole-3-methanol	GO:0071681	8.92	CTNNA1 CDH1

Molecular functions related to Microinvasive Gastric Cancer according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	P-type sodium:potassium-exchanging transporter activity	GO:0005391	9.46	ATP4A ATP12A
2	P-type potassium transmembrane transporter activity	GO:0008556	8.96	ATP4A ATP12A
3	P-type potassium:proton transporter activity	GO:0008900	8.92	ATP4A ATP12A