Microscopic Colitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: MCR191 MIFTS: 47	Microscopic Colitis Categories: Gastrointestinal diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

Sources

Aliases & Classifications for Microscopic Colitis

MalaCards integrated aliases for Microscopic Colitis:

Name: Microscopic Colitis ¹² ¹⁵

Colitis, Microscopic ⁴⁴ ⁷³

Classifications:

MalaCards categories:
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0060182

ICD10 ³³ K52.83

MeSH ⁴⁴ D046728

NCIt ⁵⁰ C38504

UMLS ⁷³ C0400821

Sources

Summaries for Microscopic Colitis

Disease Ontology : ¹² A colitis that can only be diagnosed_by the examination of colon tissue under a microscope.

MalaCards based summary : Microscopic Colitis, also known as colitis, microscopic, is related to lymphocytic colitis and inflammatory bowel disease. An important gene associated with Microscopic Colitis is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are IL-2 Pathway and Allograft rejection. The drugs Budesonide and Rifaximin have been mentioned in the context of this disorder. Affiliated tissues include colon, bone and lung, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : ⁷⁶ Microscopic colitis refers to two related medical conditions which cause diarrhea: collagenous colitis... more...

Sources

Related Diseases for Microscopic Colitis

Diseases related to Microscopic Colitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 189)

#	Related Disease	Score	Top Affiliating Genes
1	lymphocytic colitis	32.4	ATP12A ATP4A
2	inflammatory bowel disease	29.8	HLA-DQB1 HLA-DRB1 IL2 TNF
3	celiac disease 1	29.2	ATP12A ATP4A CD79A HLA-DQB1 IL2 TNF
4	collagenous colitis	12.1
5	colitis	10.9
6	diarrhea	10.4
7	microscopic polyangiitis	10.3	HLA-DRB1 TNF
8	anca-associated vasculitis	10.3	HLA-DRB1 TNF
9	limbic encephalitis with lgi1 antibodies	10.3	HLA-DQB1 HLA-DRB1
10	actinic prurigo	10.3	HLA-DRB1 TNF
11	narcolepsy 2	10.3	HLA-DQB1 HLA-DRB1
12	sympathetic ophthalmia	10.2	HLA-DRB1 TNF
13	autoimmune polyglandular syndrome type 3	10.2	HLA-DQB1 HLA-DRB1
14	nontuberculous mycobacterial lung disease	10.2	HLA-DRB1 TNF
15	hypersomnia	10.2	HLA-DQB1 HLA-DRB1
16	metal allergy	10.2	HLA-DQB1 HLA-DRB1
17	lichen planopilaris	10.2	HLA-DQB1 HLA-DRB1
18	central nervous system vasculitis	10.2	HLA-DRB1 TNF
19	type ii mixed cryoglobulinemia	10.2	HLA-DQB1 HLA-DRB1
20	rheumatoid vasculitis	10.2	HLA-DRB1 TNF
21	narcolepsy 1	10.2	HLA-DQB1 HLA-DRB1
22	irritable bowel syndrome	10.2
23	chronic pulmonary heart disease	10.2	SLC6A4 TNF
24	lichen sclerosus	10.2	HLA-DQB1 HLA-DRB1
25	whipple disease	10.2	HLA-DQB1 HLA-DRB1
26	pityriasis rosea	10.2	HLA-DQB1 HLA-DRB1
27	pediatric multiple sclerosis	10.2	HLA-DQB1 HLA-DRB1
28	idiopathic achalasia	10.2	HLA-DQB1 TNF
29	cardiac sarcoidosis	10.2	HLA-DQB1 TNF
30	osteonecrosis of the jaw	10.2	HLA-DQB1 HLA-DRB1
31	cow milk allergy	10.2	CD79A TNF
32	chronic graft versus host disease	10.2	CD79A TNF
33	idiopathic bronchiectasis	10.2	HLA-DQB1 HLA-DRB1
34	osteosclerotic myeloma	10.2	CD79A TNF
35	peanut allergy	10.2	HLA-DQB1 HLA-DRB1
36	hemorrhagic fever	10.2	HLA-DRB1 TNF
37	sialadenitis	10.2	HLA-DQB1 TNF
38	alveolar echinococcosis	10.2	HLA-DRB1 TNF
39	uveoparotid fever	10.2	LYZ TNF
40	cytomegalovirus retinitis	10.2	HLA-DQB1 TNF
41	hypersensitivity vasculitis	10.2	CD79A HLA-DRB1
42	congenital toxoplasmosis	10.2	CD79A HLA-DQB1
43	periodic fever, familial, autosomal dominant	10.2	LYZ TNF
44	orofacial granulomatosis	10.2	CD79A TNF
45	acute disseminated encephalomyelitis	10.2	HLA-DQB1 HLA-DRB1
46	oral tuberculosis	10.2	IL2 TNF
47	immunoglobulin alpha deficiency	10.1	CD79A HLA-DQB1
48	hypersensitivity reaction type iii disease	10.1	CD79A TNF
49	berylliosis	10.1	HLA-DRB1 IL2
50	beryllium disease	10.1	HLA-DQB1 HLA-DRB1 TNF

Graphical network of the top 20 diseases related to Microscopic Colitis:

Sources

Symptoms & Phenotypes for Microscopic Colitis

GenomeRNAi Phenotypes related to Microscopic Colitis according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased viability	GR00381-A-1	9.28	CD79A HLA-DQB1 SLC6A4
2	Decreased viability	GR00381-A-3	9.28	CD79A HLA-DQB1 SLC6A4
3	Decreased viability	GR00402-S-2	9.28	CD79A HLA-DQB1 SLC6A4

MGI Mouse Phenotypes related to Microscopic Colitis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	digestive/alimentary	MP:0005381	9.87	ATP12A ATP4A HLA-DQB1 IL2 LYZ PTEN
2	homeostasis/metabolism	MP:0005376	9.81	ATP12A ATP4A CD79A HLA-DQB1 IL2 LYZ
3	endocrine/exocrine gland	MP:0005379	9.8	ATP4A HLA-DQB1 IL2 LYZ PTEN SLC6A4
4	liver/biliary system	MP:0005370	9.43	CD79A HLA-DQB1 IL2 LYZ PTEN TNF
5	neoplasm	MP:0002006	9.1	ATP4A CD79A IL2 LYZ PTEN TNF

Sources

Drugs & Therapeutics for Microscopic Colitis

Drugs for Microscopic Colitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Budesonide

Approved

Phase 3,Not Applicable

51333-22-3

63006 5281004

Synonyms:

(11b,16a)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione

(11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione

(11-beta,16-alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione

(11β,16α)-16,17-(butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione

(4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one

(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one

(R,S)-11b,16a,17,21,tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with buty raldehyde

(RS)-(11beta,16alpha)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

(RS)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde

(S)-16alpha,17-(Butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione

11beta,21-dihydroxy-16alpha,17alpha-(butane-1,1-diyldioxy)pregna-1,4-diene-3,20-dione

16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione

16,17-Butylidenebis(oxy)-11-,21-dihydroxypregna-1,4-diene-3,20-dione

16alpha(R),17-(Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione

16-alpha,17-alpha-Butylidenedioxy-11-beta,21-dihydroxy-1,4-pregnadiene-3,20-dione

16alpha-,17alpha--butylidenedioxypregna-1,4-diene-11beta-,21-diol-3,20-dione

51333-22-3

AC1L1DQE

AC1L1Y6Y

AC1L22VC

AC1MHWI7

AC-4697

B 7777

B7777_SIGMA

Bidien

Bio-0010

BPBio1_000523

BRD-A34299591-001-03-4

BRD-A82238138-001-01-7

BSPBio_000475

BSPBio_002160

Budecort Inhaler

Budenofalk

Budeson

budesonide

Budesonide (JAN/USAN/INN)

Budesonide [USAN:INN:BAN:JAN]

Budesonide Easyhaler

Budesonide MMX

Budesonide, (R)-isomer

Budesonide, (S)-isomer

Budesonido

Budesonido [INN-Spanish]

Budesonidum

Budesonidum [INN-Latin]

Budiair

Budicort

C25H34O6

CCRIS 5230

CHEBI:3207

CHEBI:656601

CHEMBL1370

CID2462

CID3033890

CID40000

CID5281004

CID63006

Cortivent

CPD000058337

D00246

DB01222

Desowen

Dexbudesonide

Dexbudesonide [INN]

DivK1c_000475

EINECS 257-139-7

EINECS 257-160-1

EINECS 257-161-7

Entocort

Entocort EC

Entocort EC (TN)

EU-0100174

Giona Easyhaler

HMS1569H17

HMS1921I22

HMS2094I13

HMS501H17

Horacort

IDI1_000475

Inflammide

KBio1_000475

KBio3_001660

KBioGR_001361

Lopac0_000174

LS-187734

LS-7235

MAP-0010

Micronyl

Miflonide

MLS000028507

MLS001077323

MLS002207112

MolPort-002-529-265

MolPort-003-666-332

MolPort-003-986-909

NCGC00015165-03

NCGC00021318-03

NCGC00021318-06

NCGC00089747-02

NCGC00089747-03

NCGC00089747-04

NCGC00178789-01

NINDS_000475

Noex

Preferid

Pregna-1,4-diene-3,20-dione, 16,17-butylidenebis(oxy)-11,21-dihydroxy-, (11beta,16alpha(R))-, and 16alpha,17-((S)-Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione

Prestwick_840

Prestwick0_000518

Prestwick1_000518

Prestwick2_000518

Prestwick3_000518

Pulmaxan

Pulmaxan turbohaler

Pulmicort

Pulmicort (TN)

Pulmicort Flexhaler

Pulmicort Nebuamp

Pulmicort Respules

Pulmicort Topinasal

Pulmicort turbuhaler

Pulmicort Turbuhaler

Respules

Rhinocort

Rhinocort alpha

Rhinocort Aqua

Rhinocort Turbuhaler

Rhinocort, Pulmicort , Entocort, Symbicort, Noex. Entocort EC, Budesonide

Rhinosol

S 1320

S1286_Selleck

S-1320

SAM002699898

SMR000058337

SPBio_000586

SPBio_002396

SPECTRUM1500813

Spectrum2_000623

Spectrum3_000620

Spectrum4_000821

Spectrum5_001738

Spirocort

ST51039033

TL8003397

Tridesilon

UDB

UNII-168L5HT37P

UNII-2HI1006KPH

UNII-Q3OKS62Q6X

Unit dose budesonide

ZINC03938751

ZINC04097286

Rifaximin

Approved, Investigational

Phase 3

80621-81-4

6436173

Synonyms:

(2S,16Z,18E,20S,21S,22R,23R,24R,25S,26S,27S,28E)-5,6,21,23,25 Pentahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)benzofuro(4,5-e)pyrido(1,2-a)benzimidazole-1,15(2H)-dione, 25-acetate

4-deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4C)rifamycin

4-Deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4C)rifamycin

4-Deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4-c)rifamycin SV

80621-81-4

88747-56-2

AC-19112

alpha-0817185

Bio-0556

BRN 3584528

C43H51N3O11

CHEMBL1617

D02554

DB01220

Fatroximin

Flonorm

L 105

L 105 (Ansamacrolide antibiotic)

L 105SV

Lormyx

LS-178059

LS-64147

Lumenax

MLS000759430

Normix

Redactiv

RedActiv

Rifacol

Rifamixin

Rifamycin L 105

Rifamycin L 105SV

Rifaxidin

Rifaximin

Rifaximin (USAN/INN)

Rifaximin [USAN:INN]

Rifaximina

Rifaximina [Spanish]

Rifaximine

Rifaximine [French]

Rifaximinum

Rifaximinum [Latin]

Rifaximinun

Rifaxin

Ritacol

S1790_Selleck

SMR000466324

Spiraxin

UNII-L36O5T016N

Xifaxan

Xifaxan, Rifacol, Fatroximin, Rifaximin

Xifaxsan

Xifaxsan (TN)

Peripheral Nervous System Agents

Phase 2, Phase 3,Phase 3,Not Applicable

Analgesics

Phase 2, Phase 3

Antirheumatic Agents

Phase 2, Phase 3

Anti-Inflammatory Agents, Non-Steroidal

Phase 2, Phase 3

Anti-Inflammatory Agents

Phase 2, Phase 3,Phase 3,Not Applicable

Mesalamine

Phase 2, Phase 3

89-57-6

Analgesics, Non-Narcotic

Phase 2, Phase 3

Hormone Antagonists

Phase 3,Not Applicable

Hormones

Phase 3,Not Applicable

Bronchodilator Agents

Phase 3,Not Applicable

Autonomic Agents

Phase 3,Not Applicable

Respiratory System Agents

Phase 3,Not Applicable

Anti-Asthmatic Agents

Phase 3,Not Applicable

glucocorticoids

Phase 3,Not Applicable

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 3,Not Applicable

Rifamycins

Phase 3

Anti-Bacterial Agents

Phase 3

Nucleic Acid Synthesis Inhibitors

Phase 3

rifamycin SV

Phase 3

Anti-Infective Agents

Phase 3

Gastrointestinal Agents

Phase 3,Not Applicable

Pharmaceutical Solutions

Not Applicable

Cola

Not Applicable

Anti-Ulcer Agents

Not Applicable

Antacids

Not Applicable

Bismuth

Not Applicable

7440-69-9

16682734 105143

Synonyms:

17034_FLUKA

24267-48-9

25243-76-9

264008_ALDRICH

265462_ALDRICH

265470_ALDRICH

452386_ALDRICH

556130_ALDRICH

7440-69-9

83Bi

95372_ALDRICH

95372_FLUKA

95375_FLUKA

AC1NSDYX

AC1O4PN8

AR-1I0647

Bi(3+)

Bismut

bismuth

Bismuth standard for AAS

Bismuth standard for ICP

Bismuth(III) cation

Bismuth(III) nitrate solution

BISMUTH, 99.95%

BISMUTH, 99.999%

Bismuth, elemental

Bismuth-209

bismuto

Bisumth(3+) ion

C15471

CHEBI:33301

CID5359367

EINECS 231-177-4

HSDB 2078

LS-44708

LTBB002773

MolPort-003-925-759

Wismut

Interventional clinical trials:

(show all 17)

#	Name	Status	NCT ID	Phase	Drugs
1	Trial of Mesalamine for the Treatment of Active Microscopic Colitis	Completed	NCT00952952	Phase 2, Phase 3	Mesalamine
2	Budesonide Treatment for Lymphocytic Colitis	Completed	NCT00180050	Phase 3	Budesonide
3	Budesonide for Maintenance Treatment of Collagenous Colitis	Completed	NCT00180076	Phase 3	Budesonide
4	Budesonide for Induction of Remission in Incomplete Microscopic Colitis	Recruiting	NCT02142634	Phase 3	Budesonide granules 9 mg;Placebo granules
5	Rifaximin-treatment of Collagenous Colitis	Not yet recruiting	NCT03658993	Phase 3	Rifaximin 550 MG
6	Usefulness of Chromoendoscopy in Diagnosing Microscopic Colitis	Unknown status	NCT01504048	Not Applicable
7	Microbe-Gut Interaction in Microscopic Colitis and Post-Infectious Irritable Bowel Syndrome (IBS)	Unknown status	NCT01787253
8	Case-Control Study to Identify Risk Factors for Microscopic Colitis	Completed	NCT01928667
9	Ussing Experiments to Evaluate the Role of Medication-induced Microscopic Colitis	Completed	NCT02303132	Not Applicable
10	Risk Factors for Microscopic Colitis	Recruiting	NCT02699333
11	Identification/Characterization of Changes in Microscopic Colitis	Recruiting	NCT03063957
12	Interest of Pan-capsule in Symptomatic Patients Suspected of Irritable Bowel Syndrome Requiring Colonoscopy	Recruiting	NCT03806959	Not Applicable
13	Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy	Recruiting	NCT02284802	Not Applicable
14	Fecal Microbiota Transplantation for C Diff Infection	Recruiting	NCT01905709	Not Applicable
15	Faecal Microbiota Transplantation in Patients With Microscopic Colitis	Enrolling by invitation	NCT03275467	Not Applicable
16	FMT in Inflammatory Bowel Disease	Not yet recruiting	NCT03477032
17	Treatment of Microscopic Colitis	Terminated	NCT00184171	Not Applicable	Budesonide;Bismuth;Fiber

Search NIH Clinical Center for Microscopic Colitis

Cochrane evidence based reviews: colitis, microscopic

Sources

Genetic Tests for Microscopic Colitis

Sources

Anatomical Context for Microscopic Colitis

MalaCards organs/tissues related to Microscopic Colitis:

⁴¹

Colon, Bone, Lung, Heart, Lymph Node, Eye, Spinal Cord

Sources

Publications for Microscopic Colitis

Articles related to Microscopic Colitis:

(show top 50) (show all 373)

#	Title	Authors	Year
1	Decreased risk for microscopic colitis and inflammatory bowel disease among patients with reflux disease. ( 29603881 )	Sonnenberg A....Genta R.M.	2018
2	Microscopic colitis-microbiome, barrier function and associated diseases. ( 29610731 )	van Hemert S....Marlicz W.	2018
3	Microscopic colitis in Denmark and Sweden: incidence, putative risk factors, histological assessment and endoscopic activity. ( 29852792 )	Davidson S....Munck L.K.	2018
4	Smoking is Associated with an Increased Risk of Microscopic Colitis: Results From Two Large Prospective Cohort Studies of US Women. ( 29370359 )	Burke K.E....Khalili H.	2018
5	The subtypes of microscopic colitis from a pathologist's perspective: past, present and future. ( 29610757 )	Engel P.J.H....Kristensson M.	2018
6	Microscopic colitis: a population-based case series over a 9-year period in Northern Ireland. ( 29742325 )	Moore M....Loughrey M.B.	2018
7	Pembrolizumab-Induced Microscopic Colitis. ( 29610496 )	Ahmed M....Francis G.	2018
8	Clozapine Associated With Microscopic Colitis in the Setting of Biopsy-Proven Celiac Disease. ( 29424803 )	Holz K....Margolis R.L.	2018
9	High prevalence of irritable bowel syndrome-type symptoms in microscopic colitis: implications for treatment. ( 29977339 )		2018
10	Risk of osteoporosis in microscopic colitis. ( 29460653 )		2018
11	Genetic Variation and Gene Expression Levels of Tight Junction Genes Indicates Relationships Between PTEN as well as MAGI1 and Microscopic Colitis. ( 29204743 )		2018
12	Associations of Microscopic Colitis With Other Lymphocytic Disorders of the Gastrointestinal Tract. ( 29535059 )		2018
13	Microscopic colitis in patients with ulcerative colitis or Crohn's disease: a retrospective observational study and review of the literature. ( 29546806 )		2018
14	Microscopic Colitis: A Rare Cause of Pseudomembranes. ( 29981436 )		2018
15	Farnesoid X Receptor Expression in Microscopic Colitis: A Potential Role in Disease Etiopathogenesis. ( 29457048 )		2018
16	Obesity and Weight Gain Since Early Adulthood are Associated With a Lower Risk of Microscopic Colitis. ( 30529732 )	Liu PH...Khalili H	2018
17	Do Sex Hormones Cause, or Are They Only Associated With, Microscopic Colitis? ( 30419213 )	Pabla B...Ness RM	2018
18	Microscopic colitis: a narrative review with clinical approach. ( 30486642 )	Mosso E...Pellicano R	2018
19	Letter: the association between the use of different proton pump inhibitors and microscopic colitis should be re-evaluated-author's reply. ( 30318693 )	Bonderup OK	2018
20	Microscopic colitis: Diarrhoea or constipation. ( 30323375 )	Iqbal U...Anwar H	2018
21	Proinflammatory Sulfur-Reducing Bacteria Are More Abundant in Colonic Biopsies of Patients with Microscopic Colitis Compared to Healthy Controls. ( 30324555 )	Millien V...Shah R	2018
22	Vedolizumab in refractory microscopic colitis: an international case series. ( 30329034 )	Rivi?re P...Van Assche G	2018
23	Antidepressants and its relationship with microscopic colitis. ( 30338777 )	Hern?ndez-Huerta D...Mesonero-Gismero F	2018
24	Editorial: proton pump inhibitors (PPIs) and microscopic colitis. ( 30281829 )	Krol R...van Oijen MGH	2018
25	Letter: the association between the use of different proton pump inhibitors and microscopic colitis should be re-evaluated. ( 30318685 )	Tao P...Wang S	2018
26	Identification of Menopausal and Reproductive Risk Factors for Microscopic Colitis-Results From the Nurses' Health Study. ( 30144433 )	Burke KE...Khalili H	2018
27	Can Immune Checkpoint Inhibitors Induce Microscopic Colitis or a Brand New Entity? ( 30169584 )	Choi K...Wang Y	2018
28	Dietary Gluten Intake and Risk of Microscopic Colitis Among US Women without Celiac Disease: A Prospective Cohort Study. ( 30181535 )	Liu PH...Khalili H	2018
29	Fatigue and its associated factors in microscopic colitis. ( 30228831 )	Kane JS...Ford AC	2018
30	Significant association between the use of different proton pump inhibitors and microscopic colitis: a nationwide Danish case-control study. ( 30039564 )	Bonderup OK...Hallas J	2018
31	Prevalence, Pathogenesis, Diagnosis, and Management of Microscopic Colitis. ( 28669150 )	Gentile N....Yen E.F.	2017
32	Microscopic Colitis: A Review of Collagenous and Lymphocytic Colitis. ( 29230146 )	Boland K....Nguyen G.C.	2017
33	Letter: the definition of budesonide dependence in microscopic colitis-authors' reply. ( 28805323 )	Cotter T.G....Pardi D.S.	2017
34	Are the anti-CdtB and anti-vinculin antibodies really ready for use in patients with diarrhea in Mexico? Regarding microscopic colitis. ( 28318707 )	Carmona-SA!nchez R.	2017
35	Endoscopic features of microscopic colitis: The &quot;grid-like&quot; pattern detected with HD+ colonoscopy plus i-scan. ( 28174001 )	Grassia R....Buffoli F.	2017
36	Continuing Medical Education: January 2017: Diagnosis and Management of Microscopic Colitis. ( 28050030 )		2017
37	Endoscopic findings and colonic perforation in microscopic colitis: A systematic review. ( 28847471 )	Marlicz W....Koulaouzidis A.	2017
38	Th1 Pathway: The Missing Link Between Inflammatory Bowel Disease and Microscopic Colitis? ( 28776143 )	Carrasco A....FernA!ndez-BaA+ares F.	2017
39	Macroscopic findings, incidence and characteristics of microscopic colitis in a large cohort of patients from the United Kingdom. ( 28562114 )	Kane J.S....Ford A.C.	2017
40	Is Epstein-Barr virus infection associated with the pathogenesis of microscopic colitis? ( 29078077 )	Rizzo A.G....Cottone M.	2017
41	Continuing Medical Education Questions: January 2017: Diagnosis and Management of Microscopic Colitis. ( 28050038 )	Carpenter S.L.	2017
42	Extended-release Multimatrix Budesonide for Microscopic Colitis. ( 28328627 )	Kamboj A.K....Pardi D.S.	2017
43	Early Life Exposure, Lifestyle, and Comorbidity as Risk Factors for Microscopic Colitis: A Case-Control Study. ( 28471835 )	Verhaegh B.P.M....Jonkers D.M.A.E.	2017
44	Symptomatic Microscopic Colitis Atop Quiescent Inflammatory Bowel Disease: A Case Series. ( 29299484 )	Megna B....Caldera F.	2017
45	Antidepressant-Associated Microscopic Colitis: A Case Report and Literature Review. ( 28347506 )	Salter T.G....Williams M.D.	2017
46	Case report: Pentoxifylline treatment in microscopic colitis. ( 29145246 )		2017
47	Diagnosis and Management of Microscopic Colitis. ( 27897155 )		2017
48	Microscopic Colitis After Fecal Microbiota Transplant. ( 28761890 )		2017
49	Letter: the definition of budesonide dependence in microscopic colitis. ( 28805319 )		2017
50	Over 90% of cases of Microscopic Colitis can be diagnosed by performing a short colonoscopy. ( 28215538 )		2017

Sources

Genes for Microscopic Colitis

Genes related to Microscopic Colitis (0 elite genes):

(show all 11)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TNF	Tumor Necrosis Factor	Protein Coding	21.03	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	SLC6A4	Solute Carrier Family 6 Member 4	Protein Coding	19.93	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	16.93	GeneCards inferred via : Publications (show sections)
4	ATP12A	ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit	Protein Coding	16.79	DISEASES inferred ¹⁵
5	ATP4A	ATPase H+/K+ Transporting Subunit Alpha	Protein Coding	16.79	DISEASES inferred ¹⁵
6	MAGI1	Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 1	Protein Coding	16.58	GeneCards inferred via : Publications (show sections)
7	HLA-DQB1	Major Histocompatibility Complex, Class II, DQ Beta 1	Protein Coding	16.58	GeneCards inferred via : Publications (show sections)
8	CD79A	CD79a Molecule	Protein Coding	16.58	GeneCards inferred via : Publications (show sections)
9	PTEN	Phosphatase And Tensin Homolog	Protein Coding	16.58	GeneCards inferred via : Publications (show sections)
10	LYZ	Lysozyme	Protein Coding	16.58	GeneCards inferred via : Publications (show sections)
11	IL2	Interleukin 2	Protein Coding	16.58	GeneCards inferred via : Publications (show sections)

Sources

Variations for Microscopic Colitis

Sources

Expression for Microscopic Colitis

Search GEO for disease gene expression data for Microscopic Colitis.

Sources

Pathways for Microscopic Colitis

Pathways related to Microscopic Colitis according to GeneCards Suite gene sharing:

(show all 16)

#	Super pathways	Score	Top Affiliating Genes
1	IL-2 Pathway ⁶⁴ Show member pathways ErbB Family Pathway ⁶⁴ ErbB2-ErbB3 Heterodimers ⁶⁴ ErbB4 Pathway ⁶⁴ Growth Hormone Signaling ⁶⁴ HMGB1 Pathway ⁶⁴ IL-4 Pathway ⁶⁴ LPS Stimulated MAPK Signaling ⁶⁴ PACAP Signaling ⁶⁴ PI3K Signaling in B-Lymphocyte ⁶⁴ Prolactin Signaling ⁶⁴ Thrombopoietin Pathway ⁶⁴ TREM1 Pathway ⁶⁴ UVC-Induced MAPK Signaling ⁶⁴	12.62	CD79A HLA-DQB1 HLA-DRB1 IL2 PTEN TNF
2	Allograft rejection ¹ ³⁷ Show member pathways Antigen processing and presentation ³⁷ Asthma ³⁷ Autoimmune thyroid disease ³⁷ CTL Mediated Apoptosis ⁶⁴ Graft-versus-host disease ³⁷ Intestinal immune network for IgA production ³⁷ THC Differentiation Pathway ⁶⁴ Type I diabetes mellitus ³⁷ Viral myocarditis ³⁷	12.6	HLA-DQB1 HLA-DRB1 IL2 TNF
3	Influenza A ³⁷ Show member pathways Herpes simplex infection ³⁷ Measles ³⁷	12.47	HLA-DQB1 HLA-DRB1 IL2 TNF
4	Th17 cell differentiation ³⁷ Show member pathways IL-22 Pathway ⁶⁴ Immune response IL-22 signaling pathway ²² Inflammatory bowel disease (IBD) ³⁷ Th1 and Th2 cell differentiation ³⁷	12.27	HLA-DQB1 HLA-DRB1 IL2 TNF
5	Human T-cell leukemia virus 1 infection ³⁷	12.03	HLA-DQB1 HLA-DRB1 IL2 TNF
6	Epstein-Barr virus infection ³⁷	12.02	HLA-DQB1 HLA-DRB1 TNF
7	Toxoplasmosis ³⁷ Show member pathways Leishmaniasis ³⁷	11.96	HLA-DQB1 HLA-DRB1 TNF
8	ICos-ICosL Pathway in T-Helper Cell ⁶⁴ Show member pathways Calcium Mediated T-Cell Apoptosis ⁶⁴ CD28 Signaling in T-Helper Cell ⁶⁴	11.94	HLA-DQB1 HLA-DRB1 IL2 PTEN
9	Tuberculosis ³⁷	11.92	HLA-DQB1 HLA-DRB1 TNF
10	Immune response NFAT in immune response ²² Show member pathways Immune response CD28 signaling ²² Immune response ICOS pathway in T-helper cell ²² Immune response T cell receptor signaling pathway ²²	11.91	CD79A HLA-DQB1 HLA-DRB1 IL2 TNF
11	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	11.7	CD79A IL2 TNF
12	Hematopoietic cell lineage ³⁷	11.57	HLA-DQB1 HLA-DRB1 TNF
13	Rheumatoid arthritis ³⁷	11.5	HLA-DQB1 HLA-DRB1 TNF
14	T-Cell Receptor and Co-stimulatory Signaling ¹	11.04	IL2 PTEN
15	IL12 signaling mediated by STAT4 ¹	10.97	HLA-DRB1 IL2
16	Cytokines and Inflammatory Response ¹	10.26	HLA-DRB1 IL2 TNF

Sources

GO Terms for Microscopic Colitis

Cellular components related to Microscopic Colitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	plasma membrane	GO:0005886	9.28	ATP12A ATP4A CD79A HLA-DQB1 HLA-DRB1 MAGI1
2	clathrin-coated endocytic vesicle membrane	GO:0030669	9.26	HLA-DQB1 HLA-DRB1
3	integral component of lumenal side of endoplasmic reticulum membrane	GO:0071556	9.16	HLA-DQB1 HLA-DRB1
4	MHC class II protein complex	GO:0042613	8.96	HLA-DQB1 HLA-DRB1

Biological processes related to Microscopic Colitis according to GeneCards Suite gene sharing:

(show all 12)

#	Name	GO ID	Score	Top Affiliating Genes
1	immune response	GO:0006955	9.8	HLA-DQB1 HLA-DRB1 IL2 TNF
2	ATP hydrolysis coupled proton transport	GO:0015991	9.51	ATP12A ATP4A
3	brain morphogenesis	GO:0048854	9.48	PTEN SLC6A4
4	cellular sodium ion homeostasis	GO:0006883	9.46	ATP12A ATP4A
5	establishment or maintenance of transmembrane electrochemical gradient	GO:0010248	9.43	ATP12A ATP4A
6	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	GO:0002504	9.4	HLA-DQB1 HLA-DRB1
7	cellular potassium ion homeostasis	GO:0030007	9.37	ATP12A ATP4A
8	response to organic substance	GO:0010033	9.33	PTEN SLC6A4 TNF
9	sodium ion export across plasma membrane	GO:0036376	9.32	ATP12A ATP4A
10	negative regulation of organ growth	GO:0046621	9.26	PTEN SLC6A4
11	humoral immune response mediated by circulating immunoglobulin	GO:0002455	8.96	HLA-DQB1 HLA-DRB1
12	immunoglobulin production involved in immunoglobulin mediated immune response	GO:0002381	8.62	HLA-DQB1 HLA-DRB1

Molecular functions related to Microscopic Colitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	peptide antigen binding	GO:0042605	9.26	HLA-DQB1 HLA-DRB1
2	sodium:potassium-exchanging ATPase activity	GO:0005391	9.16	ATP12A ATP4A
3	MHC class II receptor activity	GO:0032395	8.96	HLA-DQB1 HLA-DRB1
4	potassium:proton exchanging ATPase activity	GO:0008900	8.62	ATP12A ATP4A

Sources

Sources for Microscopic Colitis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia