MCID: MDD008
MIFTS: 24

Middle Ear Adenoma

Categories: Cancer diseases, Ear diseases, Neuronal diseases

Aliases & Classifications for Middle Ear Adenoma

MalaCards integrated aliases for Middle Ear Adenoma:

Name: Middle Ear Adenoma 12 15 70
Adenoma of the Middle Ear 12
Adenoma of Middle Ear 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5387
NCIt 50 C6834
SNOMED-CT 67 734078009
UMLS 70 C1334759

Summaries for Middle Ear Adenoma

Disease Ontology : 12 A sensory organ benign neoplasm that is located in the middle ear.

MalaCards based summary : Middle Ear Adenoma, also known as adenoma of the middle ear, is related to carcinoid syndrome and adenoma. An important gene associated with Middle Ear Adenoma is SYP (Synaptophysin). Affiliated tissues include middle ear, bone and salivary gland.

Related Diseases for Middle Ear Adenoma

Diseases related to Middle Ear Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 352)
# Related Disease Score Top Affiliating Genes
1 carcinoid syndrome 30.4 SYP ENO2 CHGA
2 adenoma 30.1 SYP MUC1 KRT7 CHGA
3 paraganglioma 30.0 SYP ENO2 CHGA
4 glomus tumor 30.0 SYP MUC1 ENO2
5 middle ear adenocarcinoma 29.9 PPY KRT7
6 neuroendocrine tumor 29.9 SYP ENO2 CHGA
7 ceruminoma 29.8 PPY KRT7
8 hidradenoma 29.8 MUC1 KRT7
9 basal cell carcinoma 29.7 SYP KRT7 CHGA
10 auditory system cancer 29.4 SYP PPY ENO2 CHGA
11 papillary carcinoma 29.1 SYP MUC1 KRT7 CHGA
12 facial paralysis 10.3
13 rare tumor 10.3
14 cholesteatoma of middle ear 10.3
15 malignant melanocytic neoplasm of the peripheral nerve sheath 10.2 SYP ENO2
16 anal neuroendocrine tumor 10.2 SYP ENO2
17 optic nerve astrocytoma 10.2 SYP ENO2
18 cerebral neuroblastoma 10.2 SYP ENO2
19 neuronal intestinal dysplasia, type b 10.2 SYP ENO2
20 lung meningioma 10.2 SYP ENO2
21 cloacogenic carcinoma 10.2 SYP ENO2
22 pineal region teratoma 10.2 SYP ENO2
23 extraosseous ewings sarcoma-primitive neuroepithelial tumor 10.2 SYP ENO2
24 intracranial primitive neuroectodermal tumor 10.2 SYP ENO2
25 nodular prostate 10.2 SYP ENO2
26 branchiootic syndrome 1 10.2
27 pleomorphic adenoma 10.2
28 cerebellar liponeurocytoma 10.2 SYP ENO2
29 ganglioneuroblastoma 10.2 SYP ENO2
30 cerebellopontine angle primitive neuroectodermal tumor 10.2 SYP ENO2
31 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.2
32 frontal lobe neoplasm 10.2 SYP ENO2
33 myoblastoma 10.2 SYP ENO2
34 pineal parenchymal tumor of intermediate differentiation 10.2 SYP ENO2
35 kidney rhabdoid cancer 10.2 SYP ENO2
36 spinal cord oligodendroglioma 10.2 SYP ENO2
37 endobronchial leiomyoma 10.2 SYP ENO2
38 orbital cancer 10.2 SYP ENO2
39 extraosseous ewing sarcoma 10.2 SYP ENO2
40 small cell osteogenic sarcoma 10.2 SYP ENO2
41 rhabdoid meningioma 10.2 SYP ENO2
42 cerebellum cancer 10.2 SYP ENO2
43 cerebellar medulloblastoma 10.2 SYP ENO2
44 askin's tumor 10.2 SYP ENO2
45 pineal gland cancer 10.2 SYP ENO2
46 primary hepatic neuroendocrine carcinoma 10.2 SYP CHGA
47 gangliocytoma 10.2 SYP ENO2
48 acinar cell cystadenocarcinoma 10.2 SYP CHGA
49 central nervous system primitive neuroectodermal neoplasm 10.2 SYP ENO2
50 gastrointestinal neuroendocrine benign tumor 10.2 SYP CHGA

Graphical network of the top 20 diseases related to Middle Ear Adenoma:



Diseases related to Middle Ear Adenoma

Symptoms & Phenotypes for Middle Ear Adenoma

Drugs & Therapeutics for Middle Ear Adenoma

Search Clinical Trials , NIH Clinical Center for Middle Ear Adenoma

Genetic Tests for Middle Ear Adenoma

Anatomical Context for Middle Ear Adenoma

The Foundational Model of Anatomy Ontology organs/tissues related to Middle Ear Adenoma:

19
Middle Ear

MalaCards organs/tissues related to Middle Ear Adenoma:

40
Bone, Salivary Gland

Publications for Middle Ear Adenoma

Articles related to Middle Ear Adenoma:

(show top 50) (show all 113)
# Title Authors PMID Year
1
Neuroendocrine adenoma of the middle ear-An intriguing entity. 61
33768844 2021
2
Preoperative Diagnosis and Treatment of Middle Ear Adenoma: A Case Report and Literature Review. 61
33719615 2021
3
Middle ear adenoma with facial palsy: A case report and a review of the literature: Middle ear adenoma with facial palsy. 61
33246746 2020
4
111In-Octreoscan SPECT/CT hybrid imaging and 68Ga-DOTANOC PET/CT in neuroendocrine adenoma of the middle ear (NAME). 61
33273780 2020
5
Middle Ear Adenoma Imitating Late Postoperative Complication. 61
32579388 2020
6
[A rare pathology of the petrous part of the temporal bone: adenoma of the middle ear]. 61
31531685 2020
7
Middle Ear Neuroendocrine Adenoma: A Case Report and Literature Review. 61
33425416 2020
8
Middle ear adenoma with neuroendocrine differentiation: Report of a rare case. 61
32129301 2020
9
Neuroendocrine Adenoma of Middle Ear Causing Acute Onset Facial Palsy- A Rare Case Report. 61
31598498 2019
10
[Clinicopathological characteristics and research progress of neuroendocrine adenoma of the middle ear]. 61
31495105 2019
11
Neuroendocrine neoplasms of the middle ear: report of 2 cases and review of the literature. 61
31934190 2019
12
Primary pleomorphic adenoma of the middle ear and mastoid. 61
30273440 2018
13
INSM1 is a Sensitive and Specific Marker of Neuroendocrine Differentiation in Head and Neck Tumors. 61
29438167 2018
14
Neuroendocrine adenoma of the middle ear presented as paragaglioma: a case report. 61
30944513 2017
15
The First Reported Case of Primary Intestinal-type Adenocarcinoma of the Middle Ear and Review of the Literature. 61
28796082 2017
16
Middle ear adenoma with uncommon presentation and literature review. 61
28611057 2017
17
Middle ear adenoma with neuroendocrine differentiation : A pediatric case report. 61
27761737 2017
18
[Violation with horizontal semicircular canal of the middle ear adenoma: a case report]. 61
28219173 2017
19
Neuroendocrine adenoma of middle ear with new bone formation and review of literature. 61
26954862 2016
20
Neuroendocrine Adenoma of the Middle Ear: A Rare Histopathological Diagnosis. 61
27429819 2016
21
[Middle ear adenoma: clinical and pathologic analysis]. 61
26888509 2015
22
Adenomatous tumors of the middle ear. 61
25769353 2015
23
'Neuroendocrine' middle ear adenomas: consistent expression of the transcription factor ISL1 further supports their neuroendocrine derivation. 61
24766278 2015
24
Recurrent neuroendocrine adenoma of the middle ear: a case report. 61
24986258 2014
25
"Neuroendocrine adenoma of the middle ear with the history of otitis media and carcinoma of the cheek: a case report". 61
25123111 2014
26
A rare case of middle ear adenoma. 61
25741045 2014
27
Neuroendocrine adenoma of the middle ear confused with congenital cholesteatoma. 61
24830979 2014
28
Neuroendocrine neoplasms of the head and neck: some suggestions for the new WHO classification of head and neck tumors. 61
24595420 2014
29
[Neuroendocrine adenoma of the middle ear]. 61
24610086 2014
30
Middle ear adenoma: case report and discussion. 61
25045567 2014
31
Middle ear adenoma with neuroendocrine differentiation: relate of two cases and literature review. 61
25992031 2013
32
[One case of invasive adenoma of the middle ear]. 61
22932248 2012
33
Huge middle ear adenoma with delayed facial nerve paralysis. 61
22711394 2012
34
A case of middle ear adenoma. 61
24653866 2012
35
Endolymphatic sac tumor: case report and review of the literature. 61
22472343 2012
36
Adenomatous tumors of the middle ear and temporal bone: clinical, morphological and tumor biological characteristics of challenging neoplastic lesions. 61
21863251 2012
37
Neuroendocrine adenoma of the middle ear with extension into the external auditory canal. 61
22716008 2012
38
Neuroendocrine adenoma of the middle ear. 61
21527867 2012
39
A white mass behind the tympanic membrane: adenoma of the middle ear with neuroendocrine differentiation. 61
21659937 2011
40
Neuroendocrine adenoma of the middle ear (NAME) mimicking as chronic otitis media with an episode of facial nerve palsy. 61
21838097 2011
41
[Middle ear adenoma]. 61
20436986 2009
42
Middle ear adenoma: a challenging diagnosis. 61
19369616 2009
43
Middle ear adenoma with neuroendocrine differentiation (MEA-ND) in the pediatric population. 61
19303146 2009
44
Primary extracranial meningiomas: an analysis of 146 cases. 61
19644540 2009
45
Neuroendocrine adenoma of the middle ear (NAME). 61
19358129 2009
46
Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series. 61
20111612 2009
47
[Middle ear adenoma/middle ear carcinoid--an unproblematic tumor?]. 61
19065497 2009
48
Middle ear adenoma diagnosed by recurrent facial paralysis. 61
18328653 2009
49
Middle ear adenoma/carcinoid tumour: a case report and review of the literature. 61
20345079 2009
50
[What is your diagnosis? Answer: middle ear adenoma]. 61
19402317 2009

Variations for Middle Ear Adenoma

Expression for Middle Ear Adenoma

Search GEO for disease gene expression data for Middle Ear Adenoma.

Pathways for Middle Ear Adenoma

GO Terms for Middle Ear Adenoma

Sources for Middle Ear Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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