MCID: MDD008
MIFTS: 25

Middle Ear Adenoma

Categories: Cancer diseases, Ear diseases, Neuronal diseases
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Aliases & Classifications for Middle Ear Adenoma

MalaCards integrated aliases for Middle Ear Adenoma:

Name: Middle Ear Adenoma 11 14 71
Adenoma of the Middle Ear 11
Adenoma of Middle Ear 11

Classifications:



External Ids:

Disease Ontology 11 DOID:5387
NCIt 49 C6834
SNOMED-CT 68 734078009
UMLS 71 C1334759

Summaries for Middle Ear Adenoma

Disease Ontology: 11 A sensory organ benign neoplasm that is located in the middle ear.

MalaCards based summary: Middle Ear Adenoma, also known as adenoma of the middle ear, is related to adenoma and carcinoid tumors, intestinal. An important gene associated with Middle Ear Adenoma is SYP (Synaptophysin), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include middle ear, salivary gland and bone.

Related Diseases for Middle Ear Adenoma

Diseases related to Middle Ear Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 401)
# Related Disease Score Top Affiliating Genes
1 adenoma 31.0 SYP KRT7 CHGA
2 carcinoid tumors, intestinal 30.5 SYP ENO2 CHGA
3 carcinoid syndrome 30.4 SYP ENO2 CHGA
4 glomus tumor 30.2 SYP ENO2
5 neuroendocrine tumor 29.9 SYP NCAM1 ENO2 CHGA
6 hidradenoma 29.8 KRT7 KRT5
7 eccrine acrospiroma 29.8 KRT7 KRT5
8 middle ear adenocarcinoma 29.7 PPY KRT7 KRT5
9 paraganglioma 29.6 SYP NCAM1 KRT7 ENO2 CHGA
10 ceruminoma 29.6 PPY KRT7 KRT5
11 meningioma, familial 29.5 SYP NCAM1 ENO2
12 basal cell carcinoma 28.9 SYP KRT7 KRT5 ENO2 CHGA
13 bell's palsy 10.4
14 rare tumor 10.4
15 facial paralysis 10.3
16 otorrhea 10.3
17 cholesteatoma of middle ear 10.3
18 pleomorphic adenoma 10.2
19 granular cell tumor 10.2 SYP ENO2
20 malignant melanocytic neoplasm of the peripheral nerve sheath 10.2 SYP ENO2
21 neuronal intestinal dysplasia, type b 10.2 SYP ENO2
22 optic nerve astrocytoma 10.2 SYP ENO2
23 pineal region teratoma 10.2 SYP ENO2
24 extraosseous ewings sarcoma-primitive neuroepithelial tumor 10.2 SYP ENO2
25 bile duct mucinous adenocarcinoma 10.2 SYP ENO2
26 partial cryptophthalmia 10.2 SYP ENO2
27 intracranial primitive neuroectodermal tumor 10.2 SYP ENO2
28 cerebellar liponeurocytoma 10.2 SYP ENO2
29 frontal lobe neoplasm 10.2 SYP ENO2
30 lipoma of spermatic cord 10.2 SYP ENO2
31 melanotic neuroectodermal tumor 10.2 SYP ENO2
32 paratesticular lipoma 10.2 SYP ENO2
33 mucinous cystadenofibroma 10.2 SYP KRT7
34 prostate small cell carcinoma 10.2 SYP ENO2
35 perivascular tumor 10.2 SYP ENO2
36 central nervous system mesenchymal non-meningothelial tumor 10.2 SYP ENO2
37 ectomesenchymoma 10.2 SYP ENO2
38 mature teratoma of the ovary 10.2 SYP ENO2
39 myoblastoma 10.2 SYP ENO2
40 spinal cord oligodendroglioma 10.2 SYP ENO2
41 ovary neuroendocrine neoplasm 10.2 SYP KRT7
42 cerebellar medulloblastoma 10.2 SYP ENO2
43 askin's tumor 10.2 SYP ENO2
44 endometrial transitional cell carcinoma 10.2 SYP KRT7
45 rectum neuroendocrine neoplasm 10.2 SYP KRT7
46 small cell osteogenic sarcoma 10.2 SYP ENO2
47 cystitis cystica 10.1 SYP KRT7
48 horner's syndrome 10.1 SYP ENO2
49 anal paget's disease 10.1 SYP KRT7
50 medulloepithelioma 10.1 SYP ENO2

Graphical network of the top 20 diseases related to Middle Ear Adenoma:



Diseases related to Middle Ear Adenoma

Symptoms & Phenotypes for Middle Ear Adenoma

Drugs & Therapeutics for Middle Ear Adenoma

Search Clinical Trials, NIH Clinical Center for Middle Ear Adenoma

Genetic Tests for Middle Ear Adenoma

Anatomical Context for Middle Ear Adenoma

Organs/tissues related to Middle Ear Adenoma:

FMA: Middle Ear
MalaCards : Salivary Gland, Bone

Publications for Middle Ear Adenoma

Articles related to Middle Ear Adenoma:

(show top 50) (show all 117)
# Title Authors PMID Year
1
Middle ear adenoma with facial palsy: A case report and a review of the literature. 62
33246746 2022
2
Middle Ear "Adenoma": a Neuroendocrine Tumor with Predominant L Cell Differentiation. 62
34041698 2021
3
Middle Ear Adenoma Imitating Late Postoperative Complication. 62
32579388 2021
4
Clinical and histopathological principles for the diagnosis of a recurrent paraganglioma of the jugular foramen initially diagnosed as a middle ear adenoma: illustrative case. 62
36131578 2021
5
Preoperative Diagnosis and Treatment of Middle Ear Adenoma: A Case Report and Literature Review. 62
33719615 2021
6
Treatment with somatostatin analogues and PRRT in metastatic middle ear adenoma with neuroendocrine features. 62
33982661 2021
7
Neuroendocrine adenoma of the middle ear-An intriguing entity. 62
33768844 2021
8
111In-Octreoscan SPECT/CT hybrid imaging and 68Ga-DOTANOC PET/CT in neuroendocrine adenoma of the middle ear (NAME). 62
33273780 2020
9
Middle ear adenoma with neuroendocrine differentiation: Report of a rare case. 62
32129301 2020
10
[A rare pathology of the petrous part of the temporal bone: adenoma of the middle ear]. 62
31531685 2020
11
Middle Ear Neuroendocrine Adenoma: A Case Report and Literature Review. 62
33425416 2020
12
[Clinicopathological characteristics and research progress of neuroendocrine adenoma of the middle ear]. 62
31495105 2019
13
Neuroendocrine Adenoma of Middle Ear Causing Acute Onset Facial Palsy- A Rare Case Report. 62
31598498 2019
14
Neuroendocrine neoplasms of the middle ear: report of 2 cases and review of the literature. 62
31934190 2019
15
Primary pleomorphic adenoma of the middle ear and mastoid. 62
30273440 2018
16
INSM1 is a Sensitive and Specific Marker of Neuroendocrine Differentiation in Head and Neck Tumors. 62
29438167 2018
17
The First Reported Case of Primary Intestinal-type Adenocarcinoma of the Middle Ear and Review of the Literature. 62
28796082 2017
18
Neuroendocrine adenoma of the middle ear presented as paragaglioma: a case report. 62
30944513 2017
19
Middle ear adenoma with uncommon presentation and literature review. 62
28611057 2017
20
Middle ear adenoma with neuroendocrine differentiation : A pediatric case report. 62
27761737 2017
21
[Violation with horizontal semicircular canal of the middle ear adenoma: a case report]. 62
28219173 2017
22
Neuroendocrine adenoma of middle ear with new bone formation and review of literature. 62
26954862 2016
23
Neuroendocrine Adenoma of the Middle Ear: A Rare Histopathological Diagnosis. 62
27429819 2016
24
[Middle ear adenoma: clinical and pathologic analysis]. 62
26888509 2015
25
Adenomatous tumors of the middle ear. 62
25769353 2015
26
'Neuroendocrine' middle ear adenomas: consistent expression of the transcription factor ISL1 further supports their neuroendocrine derivation. 62
24766278 2015
27
Recurrent neuroendocrine adenoma of the middle ear: a case report. 62
24986258 2014
28
"Neuroendocrine adenoma of the middle ear with the history of otitis media and carcinoma of the cheek: a case report". 62
25123111 2014
29
A rare case of middle ear adenoma. 62
25741045 2014
30
Neuroendocrine adenoma of the middle ear confused with congenital cholesteatoma. 62
24830979 2014
31
[Neuroendocrine adenoma of the middle ear]. 62
24610086 2014
32
Neuroendocrine neoplasms of the head and neck: some suggestions for the new WHO classification of head and neck tumors. 62
24595420 2014
33
Middle ear adenoma: case report and discussion. 62
25045567 2014
34
Middle ear adenoma with neuroendocrine differentiation: relate of two cases and literature review. 62
25992031 2013
35
[One case of invasive adenoma of the middle ear]. 62
22932248 2012
36
Huge middle ear adenoma with delayed facial nerve paralysis. 62
22711394 2012
37
A case of middle ear adenoma. 62
24653866 2012
38
Endolymphatic sac tumor: case report and review of the literature. 62
22472343 2012
39
Adenomatous tumors of the middle ear and temporal bone: clinical, morphological and tumor biological characteristics of challenging neoplastic lesions. 62
21863251 2012
40
Neuroendocrine adenoma of the middle ear. 62
21527867 2012
41
Neuroendocrine adenoma of the middle ear with extension into the external auditory canal. 62
22716008 2012
42
A white mass behind the tympanic membrane: adenoma of the middle ear with neuroendocrine differentiation. 62
21659937 2011
43
Neuroendocrine adenoma of the middle ear (NAME) mimicking as chronic otitis media with an episode of facial nerve palsy. 62
21838097 2011
44
[Middle ear adenoma]. 62
20436986 2009
45
Middle ear adenoma: a challenging diagnosis. 62
19369616 2009
46
Middle ear adenoma with neuroendocrine differentiation (MEA-ND) in the pediatric population. 62
19303146 2009
47
Primary extracranial meningiomas: an analysis of 146 cases. 62
19644540 2009
48
Neuroendocrine adenoma of the middle ear (NAME). 62
19358129 2009
49
Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series. 62
20111612 2009
50
[Middle ear adenoma/middle ear carcinoid--an unproblematic tumor?]. 62
19065497 2009

Variations for Middle Ear Adenoma

Expression for Middle Ear Adenoma

Search GEO for disease gene expression data for Middle Ear Adenoma.

Pathways for Middle Ear Adenoma

Pathways related to Middle Ear Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.33 SYP NCAM1 ENO2

GO Terms for Middle Ear Adenoma

Sources for Middle Ear Adenoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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