MCID: MDD009
MIFTS: 29

Middle Ear Carcinoma

Categories: Cancer diseases, Ear diseases, Neuronal diseases

Aliases & Classifications for Middle Ear Carcinoma

MalaCards integrated aliases for Middle Ear Carcinoma:

Name: Middle Ear Carcinoma 12 15 73
Carcinoma of the Middle Ear 12
Neoplasm of the Middle Ear 29
Carcinoma of Middle Ear 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4893
NCIt 50 C6089
ICD10 33 C30.1
UMLS 73 C1334760

Summaries for Middle Ear Carcinoma

Disease Ontology : 12 A middle ear cancer that has material basis in abnormally proliferating cells derives from epithelial cells.

MalaCards based summary : Middle Ear Carcinoma, also known as carcinoma of the middle ear, is related to middle ear squamous cell carcinoma and middle ear adenocarcinoma. An important gene associated with Middle Ear Carcinoma is MMP9 (Matrix Metallopeptidase 9), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Matrix Metalloproteinases. Affiliated tissues include bone and pancreas.

Related Diseases for Middle Ear Carcinoma

Graphical network of the top 20 diseases related to Middle Ear Carcinoma:



Diseases related to Middle Ear Carcinoma

Symptoms & Phenotypes for Middle Ear Carcinoma

Drugs & Therapeutics for Middle Ear Carcinoma

Search Clinical Trials , NIH Clinical Center for Middle Ear Carcinoma

Genetic Tests for Middle Ear Carcinoma

Genetic tests related to Middle Ear Carcinoma:

# Genetic test Affiliating Genes
1 Neoplasm of the Middle Ear 29

Anatomical Context for Middle Ear Carcinoma

MalaCards organs/tissues related to Middle Ear Carcinoma:

41
Bone, Pancreas

Publications for Middle Ear Carcinoma

Articles related to Middle Ear Carcinoma:

(show top 50) (show all 54)
# Title Authors Year
1
Poorly Differentiated Primary Carcinoma of the Middle Ear on 18F-FDG PET/CT. ( 30371599 )
2018
2
Carcinoma of the Middle Ear: A Review of the National Cancer Database. ( 28692593 )
2017
3
Tumor Stage-Related Role of Radiotherapy in Patients with an External Auditory Canal and Middle Ear Carcinoma. ( 27384159 )
2016
4
Intramastoid solitary neurofibroma mimicking middle ear carcinoma. ( 26788355 )
2015
5
Squamous cell carcinoma of the middle ear: report of three cases. ( 25932267 )
2015
6
Computed tomography and magnetic resonance imaging findings for primary middle-ear carcinoma. ( 23635547 )
2013
7
Squamous cell carcinoma of the middle ear. ( 22278861 )
2012
8
Primary radical radiotherapy for squamous cell carcinoma of the middle ear and external auditory cana--an historical series. ( 16817330 )
2006
9
Middle ear carcinoma originating from a primary acquired cholesteatoma: a case report. ( 15699729 )
2005
10
Primary basal cell carcinoma of the middle ear presenting as recurrent cholesteatoma. ( 10503590 )
1999
11
En bloc resection of the temporal bone by the lateral approach in carcinoma of the middle ear associated with skull base infiltration with reference to the resection of the petrous apex. ( 17171066 )
1998
12
Significance of tubal resection in surgical treatment of middle ear carcinoma. ( 9151022 )
1997
13
Prevalence of human papillomavirus in middle ear carcinoma associated with chronic otitis media. ( 9094989 )
1997
14
Mucoepidermoid carcinoma of the middle ear-a case report. ( 8730361 )
1996
15
Synchronous bilateral middle ear carcinoma. ( 8172837 )
1994
16
Primary adenoid cystic carcinoma of the middle ear and mastoid. ( 8385874 )
1993
17
Temporal bone resections for carcinoma of the middle ear and the external ear canal. ( 1463116 )
1992
18
MR and CT of squamous cell carcinoma of the middle ear and mastoid complex. ( 1950914 )
1991
19
Unusual presentation of squamous cell carcinoma of the middle ear and mastoid. ( 1999665 )
1991
20
Bilateral squamous cell carcinoma of the middle ear. ( 2394631 )
1990
21
Carcinoma of the middle ear and temporal bone. ( 3059809 )
1988
22
Basal cell carcinoma of the middle ear--a natural history. ( 3199014 )
1988
23
Bilateral carcinoma of the middle ear. ( 3625025 )
1987
24
Carcinoma of the middle ear. A case report. ( 3090293 )
1986
25
Squamous cell carcinoma of the middle ear. A 25-year retrospective study. ( 4014949 )
1985
26
Long-term observation of total temporal bone resection in carcinoma of the middle ear and temporal bone. ( 6432484 )
1984
27
Adenoid cystic carcinoma of the middle ear and temporal bone. ( 6302622 )
1983
28
Carcinoma of the middle ear and external auditory canal. ( 6305893 )
1983
29
Primary squamous cell carcinoma of the middle ear invading the cochlea. A histopathological case report. ( 6859747 )
1983
30
Radiation induced carcinoma of the middle ear. ( 6881310 )
1983
31
Middle-ear carcinoma in a girl of eighteen. ( 7391668 )
1980
32
Primary carcinoma of the middle ear and mastoid. ( 7398552 )
1980
33
Squamous cell carcinoma of the middle ear. ( 7408224 )
1980
34
Treatment of carcinoma of the middle ear. ( 414305 )
1978
35
[Middle ear carcinoma]. ( 967743 )
1976
36
Radiotherapy in carcinoma of the middle ear and auditory canal. ( 182892 )
1976
37
Radical surgery for carcinoma of the middle ear. ( 5053991 )
1972
38
Carcinoma of the middle ear. ( 5559389 )
1971
39
A case of Garcin's syndrome associated with carcinoma of the middle ear. ( 5453995 )
1970
40
Adenoid cystic carcinoma of the middle ear and mastoid cavity with a case report. ( 5231837 )
1967
41
A case of carcinoma of the middle ear presenting with facial palsy. ( 5919258 )
1966
42
Carcinoma of the middle ear. ( 4158518 )
1965
43
Metastatic mammary carcinoma of the middle ear and mastoid. ( 5842398 )
1965
44
The management of carcinoma of the middle ear. ( 13968583 )
1963
45
Carcinoma of the middle ear and mastoid: a report of 3 cases. ( 13869900 )
1962
46
The treatment of carcinoma of the middle ear by the 4 MV linear accelerator. ( 14402790 )
1960
47
Carcinoma of the middle ear with extensive spread along the eustachian tube. ( 13631356 )
1959
48
Carcinoma of the middle ear and meatus. ( 13242970 )
1955
49
On primary carcinoma of the middle ear and mastoid; its incidence, etiological factors and clinical course, with the results of treatment by surgery and radiotherapy. ( 14354343 )
1955
50
Carcinoma of the middle ear. ( 13160486 )
1954

Variations for Middle Ear Carcinoma

Expression for Middle Ear Carcinoma

Search GEO for disease gene expression data for Middle Ear Carcinoma.

Pathways for Middle Ear Carcinoma

Pathways related to Middle Ear Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.65 CSF3 MMP9
2
Show member pathways
11.25 MMP9 RECK
3 11.14 CD1A CSF3
4 10.91 MMP9 RECK
5 10.42 CSF3 MMP9

GO Terms for Middle Ear Carcinoma

Biological processes related to Middle Ear Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 8.96 MMP9 RECK
2 embryo implantation GO:0007566 8.62 MMP9 RECK

Sources for Middle Ear Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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