Migraine with Brainstem Aura disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Migraine with Brainstem Aura

MalaCards integrated aliases for Migraine with Brainstem Aura:

Name: Migraine with Brainstem Aura ⁵³

Basilar-Type Migraine ⁵³ ⁷³

Basilar Migraine ⁵³ ⁵⁵

Vertebrobasilar Migraine ⁵³

Basilar Artery Migraine ⁵³

Bickerstaff Migraine ⁵³

Brainstem Migraine ⁵³

Mba ⁵³

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

UMLS ⁷³ C0270860

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Summaries for Migraine with Brainstem Aura

NIH Rare Diseases : ⁵³ Migraine with brainstem aura (MBA) is a type of migraine headache with aura that is associated with pain at the back of the head on both sides. An aura is a group of symptoms that generally serve as a warning sign that a bad headache is coming. Auras may consist of dizziness and vertigo, slurred speech, ataxia, tinnitus, visual changes, and/or loss of balance. Although MBA can occur in men and women of all ages, they are most common in adolescent girls. The exact underlying cause of MBA is poorly understood. Migraines are likely complex disorders that are influenced by multiple genes, in combination with lifestyle and environmental factors. In rare cases, susceptibility to MBA may be caused by a change (mutation) in the ATP1A2 gene or CACNA1A gene. Treatment during an episode may include nonsteroidal anti-inflammatory drugs (NSAIDs) and antiemetic medications to help ease the symptoms.

MalaCards based summary : Migraine with Brainstem Aura, also known as basilar-type migraine, is related to migraine, familial hemiplegic, 2 and kleine-levin hibernation syndrome. An important gene associated with Migraine with Brainstem Aura is ATP1A2 (ATPase Na+/K+ Transporting Subunit Alpha 2). The drugs Topiramate and Neuroprotective Agents have been mentioned in the context of this disorder.

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Related Diseases for Migraine with Brainstem Aura

Diseases related to Migraine with Brainstem Aura via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)

#	Related Disease	Score
1	migraine, familial hemiplegic, 2	11.6
2	kleine-levin hibernation syndrome	10.1
3	recurrent hypersomnia	10.1
4	hypersomnia	10.1
5	arts syndrome	10.1
6	osteoarthritis	10.1
7	clubfoot	10.1
8	episodic ataxia, type 2	10.0
9	medulloblastoma	10.0
10	paraganglioma	10.0
11	episodic ataxia	10.0
12	headache	10.0
13	familial hemiplegic migraine	10.0
14	locked-in syndrome	10.0
15	hemiplegic migraine	10.0
16	cardiac arrhythmia	9.9
17	viral meningitis	9.9
18	transient global amnesia	9.9
19	lateral medullary syndrome	9.9
20	meningitis	9.9
21	encephalitis	9.9
22	chiari malformation	9.9

Graphical network of the top 20 diseases related to Migraine with Brainstem Aura:

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Symptoms & Phenotypes for Migraine with Brainstem Aura

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Drugs & Therapeutics for Migraine with Brainstem Aura

Drugs for Migraine with Brainstem Aura (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Topiramate

Approved

Phase 2, Phase 3

97240-79-4

5284627

Synonyms:

.beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate (9CI)

[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate

2,3:4,5-Bis-O-(1-methylethylidene) .beta.-D-fructopyranose sulfamate

2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate

2,3:4,5-Bis-O-(1-methylethylidene)-b-D-fructopyranose sulfamate

2,3:4,5-Bis-O-(1-methylethylidene)-b-D-fructopyranose sulfamic acid

2,3:4,5-Bis-O-(1-methylethylidene)-b-D-fructopyranose sulphamate

2,3:4,5-Bis-O-(1-methylethylidene)-b-D-fructopyranose sulphamic acid

2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate

2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamic acid

2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulphamate

2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulphamic acid

2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate

2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamic acid

2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulphamate

2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulphamic acid

2,3:4,5-Di- O -isopropylidene-(beta)-D-fructopyranose sulfamate

2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulfamate

2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulfamic acid

2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulphamate

2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulphamic acid

2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose sulfamate

2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose sulfamic acid

2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose sulphamate

2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose sulphamic acid

2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose sulfamate

2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose sulfamic acid

2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose sulphamate

2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose sulphamic acid

2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate

2,3-4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate

5H-Bis[1,3]dioxolo[4,5-b:4',5'-d]pyran, .beta.

97240-79-4

AKOS000424547

beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate

beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate

BIDD:GT0854

BIDD:PXR0127

BRN 5988957

BSPBio_002306

C052342

C07502

C12H21NO8S

CBChromo1_000352

CHEBI:129573

CHEMBL220492

CID5284627

Cilag brand of topiramate

CPD000466325

D00537

DB00273

-D-fructopyranose deriv.

Epitoma

Epitomax

HMS1922H06

HMS2051L09

HMS2093D20

HSDB 7531

Janssen brand of topiramate

KS-1122

KW-6485

LS-187392

LS-69764

McN 4853

McN-4853

MCN-4853

MLS000759431

MLS001424070

MolPort-001-615-062

MolPort-002-885-869

NCGC00178714-01

Ortho brand of topiramate

RWJ 17021

RWJ-17021

RWJ-17021-000

S1438_Selleck

SAM001246601

SMR000466325

SPBio_000995

SPECTRUM1505801

Spectrum2_001128

STOCK1N-71037

T0575_SIGMA

Tipiramate

Tipiramate [French]

Tipiramato

Tipiramato [Spanish]

Tipiramic acid

TL8006021

Topamac

Topamax

Topamax (TN)

Topamax sprinkle

Topamax Sprinkle

Topamax, Topiramate

Topimax

Topina

topiramate

Topiramate

Topiramate (JAN/USAN/INN)

Topiramate (TPM)

Topiramate / Placebo

Topiramate [USAN:BAN:INN]

topiramate tablet

Topiramato

Topiramato [INN-Spanish]

Topiramatum

Topiramatum [INN-Latin]

topiramatum [Latin]

Topiramic acid

Topomax

TOR

TPM

UNII-0H73WJJ391

USL-255

2

Neuroprotective Agents

Phase 2, Phase 3

3

Anticonvulsants

Phase 2, Phase 3

4

Anti-Obesity Agents

Phase 2, Phase 3

5

Protective Agents

Phase 2, Phase 3

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Dose Comparison Study of Topiramate in Pediatric Subjects With Basilar/Hemiplegic Migraine	Completed	NCT00131443	Phase 2, Phase 3	Topiramate
2	A Study of Topiramate in Pediatric Subjects With Basilar/Hemiplegic Migraine	Completed	NCT00158002	Phase 2	Topiramate
3	Continuous Treatment Study of Topiramate in Migraine Participants	Completed	NCT01799590	Phase 2	Topiramate

Search NIH Clinical Center for Migraine with Brainstem Aura

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Genetic Tests for Migraine with Brainstem Aura

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Anatomical Context for Migraine with Brainstem Aura

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Publications for Migraine with Brainstem Aura

Articles related to Migraine with Brainstem Aura:

(show all 23)

#	Title	Authors	Year
1	Exploding Head Syndrome as Aura of Migraine with Brainstem Aura: A Case Report. ( 29694468 )	Rossi F.H....Tsakadze N.	2018
2	Basilar-type migraine: An overlooked cause of loss of consciousness in pediatric emergency rooms. ( 28890047 )	Chou IC...Hong SY	2018
3	Migraine with brainstem aura: Why not a cortical origin? ( 29073774 )	Demarquay G....Mauguiere F.	2017
4	Migraine with brainstem aura presenting as recurrent hypersomnia (Kleine-Levin syndrome). ( 27343267 )		2016
5	A Valuable Case for Recognizing the Relationship between Arrhythmia and the Biology of Migraine with Brainstem Aura. ( 27404408 )		2016
6	Clinical characteristics of basilar-type migraine in the neurological clinic of a university hospital. ( 24666545 )	Ying G...Zhou J	2014
7	Unrecognized Paraganglioma of the Urinary Bladder as a Cause for Basilar-Type Migraine. ( 23735539 )	Pichler R....Steiner H.	2013
8	Basilar-type migraine patients responsive to lamotrigine: a 5-year follow-up. ( 23695071 )		2013
9	Vertebrobasilar dolichoectasia causing a presentation resembling basilar-type migraine. ( 22877683 )	Huang L...Wang Y	2013
10	Ventricular tachycardia during basilar-type migraine attack. ( 23277791 )	Pitarokoili K...Krogias C	2013
11	Basilar-type migraine with coma: case reports and literature review. ( 21463463 )	Li Q....Zhou J.	2011
12	Acute treatment of basilar-type migraine with greater occipital nerve blockade. ( 20487035 )	Baron EP...Cherian N	2010
13	CACNA1A nonsense mutation is associated with basilar-type migraine and episodic ataxia type 2. ( 19486177 )		2009
14	Relationship between basilar-type migraine and migrainous vertigo. ( 19178580 )	Wang CT...Young YH	2009
15	Basilar-type migraine. ( 19457282 )	Kaniecki RG	2009
16	Pontine capillary telangiectasia as visualized on MR imaging causing a clinical picture resembling basilar-type migraine: a case report. ( 19533201 )	Beukers RJ...Roos YB	2009
17	ATP1A2 gene mutations are not present in two sisters with basilar-type migraine associated with menses. ( 18483709 )	Cologno D....Bussone G.	2008
18	Genetic analysis of 27 Spanish patients with hemiplegic migraine, basilar-type migraine and childhood periodic syndromes. ( 18644040 )	Cuenca-Le?n E...Cormand B	2008
19	Basilar artery fenestration in a woman with basilar-type migraine. ( 17464479 )	Morelli N...Murri L	2007
20	Basilar-type migraine responsive to lamotrigine: three case reports. ( 17508181 )	d'Onofrio F...Bussone G	2007
21	A double-blind, dose comparison study of topiramate for prophylaxis of basilar-type migraine in children: a pilot study. ( 18052950 )	Lewis D...Paradiso E	2007
22	Basilar-type migraine: clinical, epidemiologic, and genetic features. ( 16567706 )	Kirchmann M....Olesen J.	2006
23	Medulloblastoma induces unusual headache with clinical picture of basilar-type migraine complicated by ischaemic infarcts. ( 16961793 )	Cannas A...Marrosu MG	2006

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Genes for Migraine with Brainstem Aura

Genes related to Migraine with Brainstem Aura (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	ATP1A2	ATPase Na+/K+ Transporting Subunit Alpha 2	Protein Coding	19.23	Novoseek inferred ⁵⁵	16344534

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Variations for Migraine with Brainstem Aura

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Expression for Migraine with Brainstem Aura

Search GEO for disease gene expression data for Migraine with Brainstem Aura.

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Pathways for Migraine with Brainstem Aura

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GO Terms for Migraine with Brainstem Aura

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Migraine with Brainstem Aura (MBA)

Aliases & Classifications for Migraine with Brainstem Aura

MalaCards integrated aliases for Migraine with Brainstem Aura:

Classifications:

External Ids:

Summaries for Migraine with Brainstem Aura

Related Diseases for Migraine with Brainstem Aura

Diseases related to Migraine with Brainstem Aura via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Migraine with Brainstem Aura:

Symptoms & Phenotypes for Migraine with Brainstem Aura

Drugs & Therapeutics for Migraine with Brainstem Aura

Drugs for Migraine with Brainstem Aura (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Genetic Tests for Migraine with Brainstem Aura

Anatomical Context for Migraine with Brainstem Aura

Publications for Migraine with Brainstem Aura

Articles related to Migraine with Brainstem Aura:

Genes for Migraine with Brainstem Aura

Genes related to Migraine with Brainstem Aura (0 elite genes):

Variations for Migraine with Brainstem Aura

Expression for Migraine with Brainstem Aura

Pathways for Migraine with Brainstem Aura

GO Terms for Migraine with Brainstem Aura

Sources for Migraine with Brainstem Aura