MBA
MCID: MGR035
MIFTS: 25

Migraine with Brainstem Aura (MBA)

Categories: Cardiovascular diseases, Eye diseases, Neuronal diseases, Rare diseases
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Aliases & Classifications for Migraine with Brainstem Aura

MalaCards integrated aliases for Migraine with Brainstem Aura:

Name: Migraine with Brainstem Aura 19
Basilar-Type Migraine 19 71
Basilar Migraine 19 53
Mba 19 75
Vertebrobasilar Migraine 19
Basilar Artery Migraines 75
Basilar Artery Migraine 19
Bickerstaff Migraine 19
Brainstem Migraine 19

Classifications:



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UMLS 71 C0270860

Summaries for Migraine with Brainstem Aura

GARD: 19 Migraine with brainstem aura (MBA) is a type of migraine headache with aura that is associated with pain at the back of the head on both sides. An aura is a group of symptoms that generally serve as a warning sign that a bad headache is coming. Auras may consist of dizziness and vertigo, slurred speech, ataxia, tinnitus, visual changes, and/or loss of balance. The exact underlying cause of MBA is poorly understood. Migraines are likely complex disorders that are influenced by multiple genes, in combination with lifestyle and environmental factors. In rare cases, susceptibility to MBA may be caused by a change in the ATP1A2 gene or CACNA1A gene.

MalaCards based summary: Migraine with Brainstem Aura, also known as basilar-type migraine, is related to migraine, familial hemiplegic, 2 and migraine with or without aura 1. An important gene associated with Migraine with Brainstem Aura is ATP1A2 (ATPase Na+/K+ Transporting Subunit Alpha 2). The drugs Topiramate and Anticonvulsants have been mentioned in the context of this disorder. Affiliated tissues include occipital lobe, trigeminal ganglion and pons.

Wikipedia 75 Basilar artery migraines: Migraine (UK: /ˈmiːɡreɪn/, US: /ˈmaɪ-/) is a common neurological disorder characterized by recurrent... more...

Mba: MBA is Master of Business Administration, a master's... more...

Related Diseases for Migraine with Brainstem Aura

Diseases related to Migraine with Brainstem Aura via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 97)
# Related Disease Score Top Affiliating Genes
1 migraine, familial hemiplegic, 2 11.2
2 migraine with or without aura 1 10.6
3 migraine with aura 10.4
4 headache 10.4
5 immunodeficiency, common variable, 10 10.3
6 fetal anticonvulsant syndrome 10.2
7 pathologic nystagmus 10.2
8 kleine-levin hibernation syndrome 10.1
9 ocular motor apraxia 10.1
10 cranioectodermal dysplasia 10.1
11 recurrent hypersomnia 10.1
12 idiopathic hypersomnia 10.1
13 hypersomnia 10.1
14 bacteremia 2 10.1
15 non-alcoholic steatohepatitis 10.1
16 visual epilepsy 10.1
17 kearns-sayre syndrome 10.0
18 familial hemiplegic migraine 10.0
19 hydrocephalus 10.0
20 amnestic disorder 10.0
21 locked-in syndrome 10.0
22 migraine without aura 10.0
23 transient global amnesia 10.0
24 inner ear disease 10.0
25 demyelinating disease 10.0
26 retrograde amnesia 10.0
27 whiplash 10.0
28 rare headache 10.0
29 breast cancer 10.0
30 down syndrome 10.0
31 48,xyyy 10.0
32 episodic ataxia, type 2 10.0
33 paragangliomas 4 10.0
34 cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1 10.0
35 migraine, familial hemiplegic, 1 10.0
36 medulloblastoma 10.0
37 meniere disease 10.0
38 motion sickness 10.0
39 pheochromocytoma 10.0
40 contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a 10.0
41 torticollis 10.0
42 mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes 10.0
43 gastrointestinal stromal tumor 10.0
44 migraine, familial hemiplegic, 3 10.0
45 developmental and epileptic encephalopathy 42 10.0
46 paraganglioma 10.0
47 telangiectasis 10.0
48 neuroendocrine tumor 10.0
49 sleep disorder 10.0
50 barre-lieou syndrome 10.0

Graphical network of the top 20 diseases related to Migraine with Brainstem Aura:



Diseases related to Migraine with Brainstem Aura

Symptoms & Phenotypes for Migraine with Brainstem Aura

Drugs & Therapeutics for Migraine with Brainstem Aura

Drugs for Migraine with Brainstem Aura (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Topiramate Approved Phase 2, Phase 3 97240-79-4 5284627
2 Anticonvulsants Phase 2, Phase 3
3 Hypoglycemic Agents Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Double-Blind Dose Comparison Study of Topiramate in Pediatric Subjects With Basilar/Hemiplegic Migraine Completed NCT00131443 Phase 2, Phase 3 Topiramate
2 An Open-Label Study of Topiramate in Pediatric Subjects With Basilar/Hemiplegic Migraine Completed NCT00158002 Phase 2 Topiramate

Search NIH Clinical Center for Migraine with Brainstem Aura

Genetic Tests for Migraine with Brainstem Aura

Anatomical Context for Migraine with Brainstem Aura

Organs/tissues related to Migraine with Brainstem Aura:

MalaCards : Occipital Lobe, Trigeminal Ganglion, Pons, Brain, Cerebellum, Heart

Publications for Migraine with Brainstem Aura

Articles related to Migraine with Brainstem Aura:

(show top 50) (show all 248)
# Title Authors PMID Year
1
Familial basilar migraine associated with a new mutation in the ATP1A2 gene. 53 62
16344534 2005
2
Coincidental occurance of episodic ataxia and multiple sclerosis: a case report and review of the literature. 62
33045894 2022
3
Vertebrobasilar artery elongation in migraine-a retrospective cross-sectional study. 62
35906498 2022
4
Update on diagnosis and differential diagnosis of vestibular migraine. 62
35015204 2022
5
Migraine with Brainstem Aura Accompanied by Disorders of Consciousness. 62
33907459 2021
6
Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability. 62
32394190 2020
7
Migraine Aura: Updates in Pathophysiology and Management. 62
32430657 2020
8
How to define migraine with brainstem aura? 62
32282900 2020
9
Neuroimaging for Migraine: The American Headache Society Systematic Review and Evidence-Based Guideline. 62
31891197 2020
10
Migraine with brainstem aura: defining the core syndrome. 62
31789370 2019
11
Getting to the Heart of the Matter: Migraine, Triptans, DHE, Ditans, CGRP Antibodies, First/Second-Generation Gepants, and Cardiovascular Risk. 62
31318457 2019
12
A singular association of migraine with brainstem aura and Alice in Wonderland syndrome. 62
31049666 2019
13
Vestibular Migraine: How to Sort it Out and What to Do About it. 62
31094996 2019
14
Episodic Migraine With and Without Aura: Key Differences and Implications for Pathophysiology, Management, and Assessing Risks. 62
30291554 2018
15
Migraine with brainstem aura: Why not a cortical origin? 62
29073774 2018
16
Basilar-type migraine: An overlooked cause of loss of consciousness in pediatric emergency rooms. 62
28890047 2018
17
Exploding Head Syndrome as Aura of Migraine with Brainstem Aura: A Case Report. 62
29694468 2018
18
Paranasal Sinus Disease in Children With Headache. 62
28831857 2017
19
Possible Involvement of the CACNA1E Gene in Migraine: A Search for Single Nucleotide Polymorphism in Different Clinical Phenotypes. 62
28573794 2017
20
Migraine with Aura or Sports-Related Concussion: Case Report, Pathophysiology, and Multidisciplinary Approach to Management. 62
28067735 2017
21
Migraine with brainstem aura presenting as recurrent hypersomnia (Kleine-Levin syndrome). 62
27343267 2016
22
A retrospective analysis of triptan and dhe use for basilar and hemiplegic migraine. 62
27062528 2016
23
Complicated Migraines. 62
27017017 2016
24
A Valuable Case for Recognizing the Relationship between Arrhythmia and the Biology of Migraine with Brainstem Aura. 62
27404408 2016
25
Field-testing of the ICHD-3 beta/proposed ICD-11 diagnostic criteria for migraine with aura. 62
25424707 2015
26
Unique Migraine Subtypes, Rare Headache Disorders, and Other Disturbances. 62
26252589 2015
27
Greater Occipital Nerve Blockade: A Safe and Effective Option for the Acute Treatment of Hemiplegic Aura. 62
26140423 2015
28
Paroxysmal nonepileptic events in infancy, childhood, and adolescence. 62
25658214 2015
29
Clinical characteristics of basilar-type migraine in the neurological clinic of a university hospital. 62
24666545 2014
30
Topiramate for migraine prophylaxis in pediatric patients. 62
24566461 2014
31
[Basilar type migraine: clinical features, differential diagnosis]. 62
24662337 2014
32
Cinnarizine for the prophylaxis of migraine associated vertigo: a retrospective study. 62
24834377 2014
33
[Cochleovestibular disorders in the patients suffering from migraine of the basilar type]. 62
25734300 2014
34
Unrecognized paraganglioma of the urinary bladder as a cause for basilar-type migraine. 62
23735539 2014
35
Migraine variants--occurrence in pediatric neurology practice. 62
23688445 2013
36
Lomerizine therapy for the treatment of benign paroxysmal vertigo of childhood transitioning into atypical basilar migraine: A case report. 62
23837033 2013
37
Vertebrobasilar dolichoectasia causing a presentation resembling basilar-type migraine. 62
22877683 2013
38
Basilar-type migraine patients responsive to lamotrigine: a 5-year follow-up. 62
23695071 2013
39
Ventricular tachycardia during basilar-type migraine attack. 62
23277791 2013
40
[Migraine with prolonged atypical aura: report of two cases]. 62
23588869 2013
41
Transient cortical blindness as a manifestation of solitary cysticercus granuloma. 62
23230251 2012
42
Dry eyes and migraines: is there really a correlation? 62
22710496 2012
43
Basic mechanisms of migraine and its acute treatment. 62
22939884 2012
44
Migraine and motion sensitivity. 62
23042062 2012
45
The enigma of the dorsolateral pons as a migraine generator. 62
22798640 2012
46
Headaches in children. 62
22868546 2012
47
[Migraine associated with conversion symptoms (Babinski's migraine): evaluation of a series of 43 cases]. 62
21889233 2012
48
[Familial hemiplegic migraine type 2: two paediatric case reports]. 62
22314763 2012
49
Basilar migraine mistaken for encephalitis. 62
21678071 2012
50
Primary headache disorders and neuro-ophthalmologic manifestations. 62
28539781 2012

Variations for Migraine with Brainstem Aura

Expression for Migraine with Brainstem Aura

Search GEO for disease gene expression data for Migraine with Brainstem Aura.

Pathways for Migraine with Brainstem Aura

GO Terms for Migraine with Brainstem Aura

Sources for Migraine with Brainstem Aura

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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