MFTS
MCID: MGR036
MIFTS: 18

Migraine with or Without Aura 2 (MFTS)

Categories: Genetic diseases, Neuronal diseases

Aliases & Classifications for Migraine with or Without Aura 2

MalaCards integrated aliases for Migraine with or Without Aura 2:

Name: Migraine with or Without Aura 2 57
Migraine, Familial Typical, Susceptibility to, 2 57 13
Migraine with or Without Aura, Susceptibility to, 2 57
Migraine, Familial Typical 2 57
Mgr2 57
Mfts 57

Characteristics:

OMIM®:

57 (Updated 05-Apr-2021)
Inheritance:
x-linked

Miscellaneous:
genetic heterogeneity, see mgr1


HPO:

31
migraine with or without aura 2:
Inheritance x-linked inheritance


Classifications:



External Ids:

OMIM® 57 300125
OMIM Phenotypic Series 57 PS157300
MedGen 41 C1848066

Summaries for Migraine with or Without Aura 2

MalaCards based summary : Migraine with or Without Aura 2, also known as migraine, familial typical, susceptibility to, 2, is related to migraine with or without aura 1. An important gene associated with Migraine with or Without Aura 2 is MGR2 (Migraine, Familial Typical, Susceptibility To). The drugs tannic acid and Benzocaine have been mentioned in the context of this disorder. Related phenotypes are photophobia and vomiting

More information from OMIM: 300125 PS157300

Related Diseases for Migraine with or Without Aura 2

Diseases in the Migraine Without Aura family:

Migraine with or Without Aura 1 Migraine with or Without Aura 2
Migraine with or Without Aura 3 Migraine Without Aura 4
Migraine with or Without Aura 5 Migraine with or Without Aura 6
Migraine with or Without Aura 8 Migraine with or Without Aura 10
Migraine with or Without Aura 11 Migraine with or Without Aura 12
Migraine with or Without Aura 13

Diseases related to Migraine with or Without Aura 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 migraine with or without aura 1 11.0

Symptoms & Phenotypes for Migraine with or Without Aura 2

Human phenotypes related to Migraine with or Without Aura 2:

31 (show all 6)
# Description HPO Frequency HPO Source Accession
1 photophobia 31 HP:0000613
2 vomiting 31 HP:0002013
3 phonophobia 31 HP:0002183
4 nausea 31 HP:0002018
5 migraine with aura 31 HP:0002077
6 migraine without aura 31 HP:0002083

Symptoms via clinical synopsis from OMIM®:

57 (Updated 05-Apr-2021)
Neurologic Central Nervous System:
photophobia
phonophobia
migraine with aura
migraine without aura

Abdomen Gastrointestinal:
vomiting
nausea

Clinical features from OMIM®:

300125 (Updated 05-Apr-2021)

Drugs & Therapeutics for Migraine with or Without Aura 2

Drugs for Migraine with or Without Aura 2 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
tannic acid Approved 1401-55-4
2
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of Physical Fitness and Physical Activity Levels of Pediatric Arrhythmia Patients With Pacemaker Completed NCT03847298
2 Feasibility and Effectiveness of Electrochemical Dermal Conductance Measurement for the Screening of Diabetic Neuropathy in Primary Care. Completed NCT03495089
3 A Study to Assess Midline Frontal Theta (MFT) Power as Measured by Stimulus-locked Electroencephalography (EEG) Before and After AKL-T01 Treatment for Improving Attention in Pediatric Participants Ages 8-12 Years Old With Attention Deficit Hyperactivity Disorder (ADHD) Recruiting NCT03844269

Search NIH Clinical Center for Migraine with or Without Aura 2

Genetic Tests for Migraine with or Without Aura 2

Anatomical Context for Migraine with or Without Aura 2

Publications for Migraine with or Without Aura 2

Articles related to Migraine with or Without Aura 2:

# Title Authors PMID Year
1
Confirmation that Xq27 and Xq28 are susceptibility loci for migraine in independent pedigrees and a case-control cohort. 57
22294494 2012
2
Familial typical migraine: significant linkage and localization of a gene to Xq24-28. 57
10982029 2000
3
Evidence for an X-linked genetic component in familial typical migraine. 57
9467004 1998
4
One-year tolerability and efficacy of sumatriptan nasal spray in adolescents with migraine: results of a multicenter, open-label study. 61
11192144 2000

Variations for Migraine with or Without Aura 2

Expression for Migraine with or Without Aura 2

Search GEO for disease gene expression data for Migraine with or Without Aura 2.

Pathways for Migraine with or Without Aura 2

GO Terms for Migraine with or Without Aura 2

Sources for Migraine with or Without Aura 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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