MGR3
MCID: MGR022
MIFTS: 16

Migraine with or Without Aura 3 (MGR3)

Categories: Genetic diseases, Neuronal diseases

Aliases & Classifications for Migraine with or Without Aura 3

MalaCards integrated aliases for Migraine with or Without Aura 3:

Name: Migraine with or Without Aura 3 57
Migraine with or Without Aura, Susceptibility to, 3 57 13
Mgr3 57

Characteristics:

OMIM®:

57 (Updated 05-Apr-2021)
Inheritance:
autosomal dominant

Miscellaneous:
long headache duration (greater than 12 hours)
variable frequency (weekly to yearly)
genetic heterogeneity, see mgr1,


HPO:

31
migraine with or without aura 3:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM® 57 607498
OMIM Phenotypic Series 57 PS157300
MedGen 41 C1843782

Summaries for Migraine with or Without Aura 3

MalaCards based summary : Migraine with or Without Aura 3, also known as migraine with or without aura, susceptibility to, 3, is related to migraine with or without aura 1. An important gene associated with Migraine with or Without Aura 3 is MGR3 (Migraine, Familial, With Or Without Aura, Susceptibility To). Related phenotypes are photophobia and vomiting

More information from OMIM: 607498 PS157300

Related Diseases for Migraine with or Without Aura 3

Diseases in the Migraine Without Aura family:

Migraine with or Without Aura 1 Migraine with or Without Aura 2
Migraine with or Without Aura 3 Migraine Without Aura 4
Migraine with or Without Aura 5 Migraine with or Without Aura 6
Migraine with or Without Aura 8 Migraine with or Without Aura 10
Migraine with or Without Aura 11 Migraine with or Without Aura 12
Migraine with or Without Aura 13

Diseases related to Migraine with or Without Aura 3 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 migraine with or without aura 1 11.0

Symptoms & Phenotypes for Migraine with or Without Aura 3

Human phenotypes related to Migraine with or Without Aura 3:

31 (show all 6)
# Description HPO Frequency HPO Source Accession
1 photophobia 31 HP:0000613
2 vomiting 31 HP:0002013
3 phonophobia 31 HP:0002183
4 nausea 31 HP:0002018
5 migraine with aura 31 HP:0002077
6 migraine without aura 31 HP:0002083

Symptoms via clinical synopsis from OMIM®:

57 (Updated 05-Apr-2021)
Neurologic Central Nervous System:
photophobia
phonophobia
migraine with aura
migraine without aura

Abdomen Gastrointestinal:
vomiting
nausea

Clinical features from OMIM®:

607498 (Updated 05-Apr-2021)

Drugs & Therapeutics for Migraine with or Without Aura 3

Search Clinical Trials , NIH Clinical Center for Migraine with or Without Aura 3

Genetic Tests for Migraine with or Without Aura 3

Anatomical Context for Migraine with or Without Aura 3

Publications for Migraine with or Without Aura 3

Articles related to Migraine with or Without Aura 3:

(show all 17)
# Title Authors PMID Year
1
Identification of a susceptibility locus for migraine with and without aura on 6p12.2-p21.1. 57
12473779 2002
2
ELISA assay employing epitope-specific monoclonal antibodies to quantify circulating HER2 with potential application in monitoring cancer patients undergoing therapy with trastuzumab. 61
32080226 2020
3
Insertion Defects of Mitochondrially Encoded Proteins Burden the Mitochondrial Quality Control System. 61
30336542 2018
4
Mitochondrial inner-membrane protease Yme1 degrades outer-membrane proteins Tom22 and Om45. 61
29138251 2018
5
Multiple roles of the Cox20 chaperone in assembly of Saccharomyces cerevisiae cytochrome c oxidase. 61
22095077 2012
6
Serine phosphorylation of glutathione S-transferase P1 (GSTP1) by PKCĪ± enhances GSTP1-dependent cisplatin metabolism and resistance in human glioma cells. 61
20654585 2010
7
Translocation and assembly of mitochondrially coded Saccharomyces cerevisiae cytochrome c oxidase subunit Cox2 by Oxa1 and Yme1 in the absence of Cox18. 61
19307606 2009
8
The human glutathione S-transferase P1 protein is phosphorylated and its metabolic function enhanced by the Ser/Thr protein kinases, cAMP-dependent protein kinase and protein kinase C, in glioblastoma cells. 61
15604283 2004
9
Genomic cloning of hGSTP1*C, an allelic human Pi class glutathione S-transferase gene variant and functional characterization of its retinoic acid response elements. 61
9407047 1997
10
Coordinate up-regulation of cyclin-dependent kinase 4 and its inhibitor p16(INK4) in human glioma cells following chloroethylnitrosourea-induced DNA damage. 61
21528331 1997
11
Detection of DNA damage in transcriptionally active genes by RT-PCR and assessment of repair of cisplatin-induced damage in the glutathione S-transferase-pi gene in human glioblastoma cells. 61
9073588 1997
12
Deletions and rearrangements inactivate the p16INK4 gene in human glioma cells. 61
8649864 1996
13
Antibody-induced activation of p185HER2 in the human lung adenocarcinoma cell line Calu-3 requires bivalency. 61
8098992 1993
14
p185 HER2/neu epitope mapping with murine monoclonal antibodies. 61
1379973 1992
15
Selection of monoclonal antibodies which induce internalization and phosphorylation of p185HER2 and growth inhibition of cells with HER2/NEU gene amplification. 61
1672668 1991
16
Alternative pathways of tobacco placental development: time of commitment and analysis of a mutant. 61
2806722 1989
17
Utilization of putrescine in tobacco cell lines resistant to inhibitors of polyamine synthesis. 61
16665927 1988

Variations for Migraine with or Without Aura 3

Expression for Migraine with or Without Aura 3

Search GEO for disease gene expression data for Migraine with or Without Aura 3.

Pathways for Migraine with or Without Aura 3

GO Terms for Migraine with or Without Aura 3

Sources for Migraine with or Without Aura 3

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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