Mikulicz Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Mikulicz Disease

MalaCards integrated aliases for Mikulicz Disease:

Name: Mikulicz Disease ¹² ¹⁵ ⁷³

Mikulicz's Disease ¹²

Mikulicz Syndrome ⁷⁶

Mikulicz' Disease ⁴⁴

Classifications:

MalaCards categories:
Anatomical: Eye diseases Immune diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the digestive system

Diseases of oral cavity, salivary glands and jaws

Diseases of salivary glands

Other diseases of salivary glands

External Ids:

Disease Ontology ¹² DOID:12900

ICD10 ³³ K11.8

MeSH ⁴⁴ D008882

NCIt ⁵⁰ C34819

SNOMED-CT ⁶⁸ 196478007 7826003

UMLS ⁷³ C0026103

Sources

Summaries for Mikulicz Disease

MalaCards based summary : Mikulicz Disease, also known as mikulicz's disease, is related to igg4-related dacryoadenitis and sialadenitis and sjogren syndrome. An important gene associated with Mikulicz Disease is IL21 (Interleukin 21). The drugs Leflunomide and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, liver and eye, and related phenotype is homeostasis/metabolism.

Wikipedia : ⁷⁶ Benign lymphoepithelial lesion is a type of benign enlargement of the parotid and/or lacrimal glands.... more...

Sources

Related Diseases for Mikulicz Disease

Diseases related to Mikulicz Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)

#	Related Disease	Score	Top Affiliating Genes
1	igg4-related dacryoadenitis and sialadenitis	11.9
2	sjogren syndrome	9.9
3	pancreatitis	9.7
4	connective tissue disease	9.7
5	lymphosarcoma	9.7
6	lupus erythematosus	9.7
7	autoimmune pancreatitis	9.7
8	lung cancer	9.7
9	lymphoma	9.7
10	dacryoadenitis	9.7	AQP5 IL21
11	common variable immunodeficiency	9.7	AICDA IL21
12	lymphoma, non-hodgkin, familial	9.4	AICDA SMUG1

Graphical network of the top 20 diseases related to Mikulicz Disease:

Sources

Symptoms & Phenotypes for Mikulicz Disease

MGI Mouse Phenotypes related to Mikulicz Disease:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	9.02	PHB PTGDR2 SMUG1 AQP5 IL21

Sources

Drugs & Therapeutics for Mikulicz Disease

Drugs for Mikulicz Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Leflunomide

Approved, Investigational

Phase 4

75706-12-6

3899

Synonyms:

210165-51-8

4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl

4-isoxazolecarboxamide,5-methyl-N-(4-(trifluoromethyl)phenyl)

5-Methylisoxazole-4-(4-trifluoromethyl)carboxanilide

5-Methylisoxazole-4-(4-trifluoromethylcarboxanilide)

5-Methylisoxazole-4-carboxylate (4-trifluoromethyl)anilide

5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide

5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide

5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide

5-methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide

5-methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide

75706-12-6

a,a,a-trifluoro-5-Methyl-4-isoxazolecarboxy-P-toluidide

A77 1486

AB00052389

AC1L1GYK

AC1Q2EVA

AC-6796

AKOS000265193

alpha,alpha,alpha-trifluoro-5-Methyl-4-isoxazolecarboxy-P-toluidide

alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide

alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-P-toluidide

AP-501/42475599

Arava

Arava (TN)

Arava, Leflunomide

Aventis behring brand OF leflunomide

Aventis Behring Brand of Leflunomide

Aventis brand OF leflunomide

Aventis Brand of Leflunomide

Aventis pharma brand OF leflunomide

Aventis Pharma Brand of Leflunomide

BIDD:PXR0189

BPBio1_000930

BRD-K78692225-001-03-9

BSPBio_000844

C045463

C07905

CAS-75706-12-6

CHEBI:6402

CHEMBL960

CID3899

D00749

DB01097

DivK1c_000916

EU-0100649

HMS1570K06

HMS1922M06

HMS2090O12

HMS502N18

Hoechst brand OF leflunomide

Hoechst Brand of Leflunomide

HSDB 7289

HWA 486

HWA-486

I06-2131

IDI1_000916

KBio1_000916

KBio2_000802

KBio2_003370

KBio2_005938

KBioSS_000802

L 5025

L5025_SIGMA

Leflunomid

Leflunomida

Leflunomida [INN-Spanish]

leflunomide

Leflunomide

Leflunomide (JAN/USAN/INN)

Leflunomide [USAN:INN]

Leflunomidum

Leflunomidum [INN-Latin]

lefunamide

Lefunomide

Lefunomide [Inn-Spanish]

Lefunomide [INN-Spanish]

Lopac0_000649

Lopac-L-5025

LS-86580

MLS000069648

MLS-0003109.0001

MLS001076267

MolPort-002-345-613

N-(4'-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide

N-(4-trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide

N-(4-Trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide

NCGC00015610-01

NCGC00015610-02

NCGC00015610-03

NCGC00015610-07

NCGC00015610-12

NCGC00022625-03

NCGC00022625-04

NCGC00022625-05

NCGC00022625-06

NCGC00022625-07

NCGC00022625-08

NINDS_000916

NSC677411

Prestwick_87

Prestwick0_000772

Prestwick1_000772

Prestwick2_000772

Prestwick3_000772

RS-34821

S1247_Selleck

SMR000058209

SPBio_002783

Spectrum_000322

SPECTRUM1503927

Spectrum5_000850

SU 101

SU 101 (pharmaceutical)

SU101

SU-101

TL8005179

UNII-G162GK9U4W

ZINC00004840

α,α,α-trifluoro-5-methyl-4-isoxazolecarboxy-P-toluidide

2

Methylprednisolone

Approved, Vet_approved

Phase 4

83-43-2

6741

Synonyms:

(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione

(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione

(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione

.DELTA.1-6.alpha.-Methylhydrocortisone

11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione

11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione

11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione

11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione

121673-01-6

1-dehydro-6alpha-Methylhydrocortisone

1-Dehydro-6alpha-methylhydrocortisone

1-dehydro-6a-Methylhydrocortisone

1-dehydro-6α-methylhydrocortisone

4-08-00-03498 (Beilstein Handbook Reference)

46436_FLUKA

46436_RIEDEL

570-35-4

6 Methylprednisolone

6.alpha.-Methylprednisolone

6923-42-8

6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione

6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione

6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione

6alpha-Methylprednisolone

6-alpha-Methylprednisolone

6a-Methyl-11b,17a,21-triol-1,4-pregnadiene-3,20-dione

6-Methylprednisolone

6α-methyl-11β,17α,21-triol-1,4-pregnadiene-3,20-dione

83-43-2

AC1L1N7A

Artisone-wyeth

Artisone-Wyeth

Besonia

Bio-0658

BPBio1_000174

BRD-K35240538-001-03-1

BRN 2340300

BSPBio_000158

CHEBI:6888

CHEMBL650

CID6741

CPD000058330

D00407

D008775

DB00959

delta(1)-6alpha-Methylhydrocortisone

Delta(1)-6alpha-Methylhydrocortisone

delta(1)-6a-Methylhydrocortisone

delta(sup 1)-6-alpha-Methylhydrocortisone

Depo-Medrol (acetate)

Dopomedrol

EINECS 201-476-4

Esametone

Firmacort

HMS1568H20

HMS2090B13

HSDB 3127

Lemod

LMST02030178

LS-118498

M0639_SIGMA

M1665

Medesone

Medixon

Medlone 21

Medrate

Medric acid

Medrol

Medrol (TN)

Medrol adt pak

Medrol Adt Pak

Medrol dosepak

Medrol Dosepak

Medrol, Solu-Medrol, Medrone, Methylprednisolone

Medrone

MEPRDL

Mesopren

Metastab

Methyleneprednisolone

Methylprednisolon

methylprednisolone

Methylprednisolone

Methylprednisolone (JP15/USP/INN)

Methylprednisolone [USAN:INN:BAN:JAN]

Methylprednisolone, 6-alpha

Methylprednisolonum

Methylprednisolonum [INN-Latin]

methylprenisolone

Metilbetasone

Metilprednisolona

Metilprednisolona [INN-Spanish]

Metilprednisolone

Metilprednisolone [Dcit]

Metilprednisolone [DCIT]

Metipred

Metrisone

Metrocort

Metysolon

MLS000028541

MLS001148159

MLS002207191

Moderin

MolPort-002-528-554

NCGC00022735-03

NCI60_001657

Nirypan

Noretona

NSC19987

NSC-19987

Predni N Tablinen

Prednol- L

Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)

Prestwick_622

Prestwick0_000279

Prestwick1_000279

Prestwick2_000279

Prestwick3_000279

Promacortine

Reactenol

S1733_Selleck

SAM002589984

Sieropresol

SMR000058330

Solomet

SPBio_002377

Summicort

Suprametil

U 7532

UNII-X4W7ZR7023

Urbason

Urbasone

Wyacort

ZINC03875560

δ(1)-6a-methylhydrocortisone

δ(1)-6α-methylhydrocortisone

3

Prednisolone

Approved, Vet_approved

Phase 4

50-24-8

5755

Synonyms:

(11b)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione

(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione

(11β)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione

.DELTA.1-Cortisol

.DELTA.1-Dehydrocortisol

.DELTA.1-Dehydrohydrocortisone

.DELTA.1-Hydrocortisone

.delta.-Cortef

.delta.-Stab

1,2-Dehydrohydrocortisone

1,4-Pregnadiene-11b,17a,21-triol-3,20-dione

1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione

1,4-Pregnadiene-11β,17α,21-triol-3,20-dione

1,4-Pregnadiene-3,20-dione-11b,17a,21-triol

1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol

1,4-Pregnadiene-3,20-dione-11β,17α,21-triol

1-Dehydrocortisol

1-Dehydrohydrocortisone

3,20-dioxo-11b,17a,21-Trihydroxy-1,4-pregnadiene

3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene

3,20-dioxo-11β,17α,21-trihydroxy-1,4-pregnadiene

46656_FLUKA

46656_RIEDEL

50-24-8

58201-11-9

8056-11-9

AC-1773

AC1L1L2E

Ak-Pred

Ak-Tate

Alphadrol

Articulose-50

Bio-0666

BPBio1_000164

BRD-K98039984-001-03-0

BRN 1354103

BSPBio_000148

Bubbli-Pred

C07369

CCRIS 980

CHEBI:8378

CHEMBL131

CID5755

Codelcortone

Co-Hydeltra

CO-Hydeltra

component of Ataraxoid

component of K-Predne-Dome

Cordrol

Cortalone

Cotogesic

Cotolone

CPD000718761

D00472

D011239

DB00860

Decaprednil

Decortin H

Delcortol

Delta F

delta(1)-Cortisol

delta(1)-Dehydrocortisol

Delta(1)-Dehydrocortisol

delta(1)-Dehydrohydrocortisone

Delta(1)-dehydrohydrocortisone

Delta(1)-Dehydrohydrocortisone

delta(1)-Hydrocortisone

Delta(1)-Hydrocortisone

delta(sup 1)-Cortisol

delta(sup 1)-Dehydrocortisol

delta(sup 1)-Dehydrohydrocortisone

delta(sup 1)-Hydrocortisone

Delta-Cortef

Delta-Cortef (TN)

Deltacortenol

Deltacortril

Deltacortril Enteric

delta-dehydrocortisol

delta-dehydrohydrocortisone

Delta-Ef-Cortelan

delta-hydrocortisone

Deltahydrocortisone

Deltasolone

Delta-stab

Delta-Stab

Deltisilone

Depo-Medrol

Derpo Pd

Derpo PD

Dexa-Cortidelt hostacortin H

Dexa-Cortidelt Hostacortin H

Di adreson F

Di Adreson F

Di-adreson F

Di-Adreson F

Di-adreson-F

DiAdresonF

Di-Adreson-F

Dicortol

Donisolone

Dydeltrone

Eazolin D

Econopred

Econopred Plus

EINECS 200-021-7

Erbacort

Erbasona

Estilsona

Fernisolone

Fernisolone P

Fernisolone-P

Flamasone

HMS1568H10

HMS2090J05

Hostacortin H

HSDB 3385

Hydeltra

Hydeltrasol

Hydeltra-Tba

Hydeltrone

Hydrodeltalone

Hydrodeltisone

Hydroretrocortin

Hydroretrocortine

Inflamase Forte

Inflamase Mild

I-Pred

K 1557

Key-Pred

Klismacort

Lentosone

Lite Pred

LMST02030179

LS-7669

Medrol

Medrol Acetate

Metacortandralone

Methylprednisolone acetate

Methylprednisolone Acetate

Meticortelone

Meti-Derm

Metreton

MLS001304083

MLS002154250

MLS002207037

MolPort-002-507-147

M-Predrol

NCGC00179649-01

Neo-Delta-Cortef

Nisolone

Nor-Pred T.B.A.

NSC 9120

NSC9120

NSC9900

Ocu-Pred

Ocu-Pred Forte

Ophtho-Tate

Orapred

P0152_SIGMA

P0637

P6004_SIGMA

Panafcortelone

Paracortol

Paracotol

Pediapred

Poly-Pred

PRDL

Precortalon

Precortancyl

Precortilon

Precortisyl

Pred Forte

Pred Mild

Predair

Predair A

Predair Forte

Predalone 50

Predalone T.B.A.

Predate

Predate Tba

Predate-50

Predcor-25

Predcor-50

Predcor-Tba

PRED-G

Predisolone sodium phosphate

Predisolone Sodium Phosphate

Predne-Dome

Prednelan

Prednicen

Predni-Dome

Predniliderm

Predniretard

Prednis

Prednisolona

Prednisolona [INN-Spanish]

prednisolone

Prednisolone (anhydrous)

Prednisolone (JP15/USP/INN)

Prednisolone [INN:BAN:JAN]

Prednisolone acetate

Prednisolone Acetate

Prednisolone sodium phosphate

Prednisolone Sodium Phosphate

Prednisolone tebutate

Prednisolone Tebutate

Prednisolonum

Prednisolonum [INN-Latin]

Predonin

Predonine

Prelone

Prenolone

Prestwick_404

Prestwick0_000274

Prestwick1_000274

Prestwick2_000274

Prestwick3_000274

Rolisone

S1737_Selleck

SAM002264639

Scherisolon

SMR000718761

Solone

SPBio_002367

Steran

Sterane

Sterolone

Supercortisol

Ulacort

Ultra Pred

Ultracorten H

Ultracortene H

Ultracortene-H

Ultracortene-hydrogen

Ultracortene-Hydrogen

UNII-9PHQ9Y1OLM

ZINC03833821

δ(1)-dehydrocortisol

δ(1)-dehydrohydrocortisone

δ(1)-hydrocortisone

4

Prednisone

Approved, Vet_approved

Phase 4

53-03-2

5865

Synonyms:

(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione

(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione

.delta. E

.delta.(sup1)-Cortisone

.delta.1-Cortisone

.delta.1-Dehydrocortisone

.delta.-Cortelan

.delta.-Cortisone

.delta.-Cortone

.delta.-E

.delta.sone

1,2-Dehydrocortisone

1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione

1,4-Pregnadiene-17a,21-diol-3,11,20-trione

1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17α,21-diol-3,11,20-trione

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione

1-Cortisone

1-Dehydrocortisone

53-03-2

68-59-7

81552_FLUKA

AC-11112

AC1L1LB2

AC1Q29EZ

Acis brand OF prednisone

ACon0_000082

ACon1_000297

Adasone

AI3-52939

Ancortone

apo-Prednisone

Apo-prednisone

Apo-Prednisone

Apotex brand OF prednisone

Aventis brand OF prednisone

Betapar

Bicortone

Bio-0649

BPBio1_000323

BRD-K85883481-001-04-2

BSPBio_000293

C07370

C21H26O5

Cartancyl

CCRIS 2646

CHEBI:8382

CHEMBL635

CID5865

Colisone

Cortan

Cortancyl

Cortidelt

Cotone

CPD001227202

Cutason

Dacorten

Dacortin

DB00635

Decortancyl

Decortin

Decortisyl

Dehydrocortisone

Dekortin

Delcortin

Dellacort

Dellacort A

delta cortelan

Delta Cortelan

Delta E

Delta E.

delta(sup 1)-Cortisone

delta(sup 1)-Dehydrocortisone

delta-1-Cortisone

delta-1-Dehydrocortisone

Delta-cortelan

Delta-Cortelan

Deltacortene

delta-Cortisone

Deltacortisone

Delta-cortisone

delta-Cortone

Deltacortone

Delta-cortone

Delta-dome

Delta-Dome

Deltasone

Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone

Deltison

Deltisona

Deltisone

Deltra

Diadreson

Di-Adreson

Diba brand OF prednisone

Econosone

EINECS 200-160-3

Encorton

Encortone

Enkortolon

Enkorton

Fawns and mcallan brand OF prednisone

Fernisone

Ferring brand OF prednisone

Fiasone

GALENpharma brand OF prednisone

Halsey drug brand OF prednisone

Hexal brand OF prednisone

HMS1568O15

HMS2090J13

Hoechst brand OF prednisone

Hostacortin

HSDB 3168

ICN brand OF prednisone

Incocortyl

In-Sone

Juvason

Kortancyl

Lichtenstein brand OF prednisone

Liquid pred

Liquid Pred

Lisacort

LMST02030180

Lodotra

LS-1325

MEGxm0_000443

Me-Korti

Merck brand OF prednisone

Merz brand OF prednisone

Metacortandracin

Meticorten

Meticorten (Veterinary)

Metrevet (Veterinary)

Mibe brand OF prednisone

MLS001061265

MLS001304073

MLS001335907

MLS001335908

MLS002154191

MLS002207083

MolPort-001-740-041

NCGC00090766-01

NCGC00090766-02

NCGC00090766-03

NCI60_000008

NCI-C04897

Nisona

Nizon

Novoprednisone

NSC 10023

NSC10023

Nurison

Orasone

Origen Prednisone

P1276

P6254_SIGMA

Panafcort

Panasol

Paracort

Parmenison

Pehacort

Pharmacia brand OF prednisone

PRD

Precort

Predeltin

Predni tablinen

Prednicen-M

Prednicorm

Prednicort

Prednicot

Prednidib

Prednilonga

Predniment

Prednison

Prednison acsis

Prednison galen

Prednison hexal

Prednisona

Prednisona [INN-Spanish]

Prednisone

Prednisone [INN:BAN]

Prednisone Intensol

Prednisonum

Prednisonum [INN-Latin]

Prednitone

Prednizon

Prednovister

Presone

Prestwick_405

Prestwick0_000077

Prestwick1_000077

Prestwick2_000077

Prestwick3_000077

Pronison

Pronisone

Rectodelt

Retrocortine

S1622_Selleck

SAM002264641

Schering-plough brand OF prednisone

Seatrace brand OF prednisone

Servisone

SK-Prednisone

SMR000718760

SMR001227202

Solvay brand OF prednisone

Sone

SPBio_002214

Sterapred

Supercortil

Trommsdorff brand OF prednisone

U 6020

Ultracorten

Ultracortene

UNII-VB0R961HZT

Winpred

WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ

Wojtab

Zenadrid

Zenadrid (veterinary)

Zenadrid [veterinary]

ZINC03875357

5

Antibodies

Phase 4

6

Anti-Inflammatory Agents

Phase 4

7

Antineoplastic Agents, Hormonal

Phase 4

8

Antirheumatic Agents

Phase 4

9

glucocorticoids

Phase 4

10

Hormone Antagonists

Phase 4

11

Hormones

Phase 4

12

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 4

13

Immunoglobulin G

Phase 4

14

Immunoglobulins

Phase 4

15

Immunosuppressive Agents

Phase 4

16

Liver Extracts

Phase 4

17

Methylprednisolone acetate

Phase 4

18

Methylprednisolone Hemisuccinate

Phase 4

19

Prednisolone acetate

Phase 4

20

Prednisolone hemisuccinate

Phase 4

21

Prednisolone phosphate

Phase 4

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Leflunomide for Maintenance of Remission in IgG4 Related Disease	Recruiting	NCT02703194	Phase 4	Prednisone;Leflunomide
2	A Prospective Cohort Study of IgG4RD in China	Recruiting	NCT01670695

Search NIH Clinical Center for Mikulicz Disease

Cochrane evidence based reviews: mikulicz' disease

Sources

Genetic Tests for Mikulicz Disease

Sources

Anatomical Context for Mikulicz Disease

MalaCards organs/tissues related to Mikulicz Disease:

⁴¹

Salivary Gland, Liver, Eye, Lung

Sources

Publications for Mikulicz Disease

Articles related to Mikulicz Disease:

(show all 21)

#	Title	Authors	Year
1	Mikulicz Disease Mimicking Intraorbital Tumors. ( 28987847 )	Murai S....Terasaka K.	2018
2	A rare case of Mikulicz disease. ( 27728670 )	Chinta V.A....Vpg N.M.	2016
3	IgG4-related Mikulicz Disease in a 76-year-old Chinese Male: A Case Report. ( 24432837 )	Wang L....Niu W.	2014
4	&quot;Quasi-symmetric&quot; FDG avidity of bilateral salivary glands in Mikulicz disease yielding false-positive staging in lung cancer. ( 22996254 )	Lin L.F....Chen C.Y.	2012
5	Th2 and regulatory immune reactions contribute to IgG4 production and the initiation of Mikulicz disease. ( 21898360 )	Tanaka A....Nakamura S.	2012
6	Connective tissue diseases: Immune responses in Mikulicz disease differ from those in SS. ( 21971284 )	Ray K.	2011
7	Highly active state of autoimmune pancreatitis with mikulicz disease. ( 19904224 )	Kubota K....Nakajima A.	2010
8	Clinicopathologic similarities between Mikulicz disease and KA1ttner tumor. ( 20015799 )	Takano K....Himi T.	2010
9	Sonographic diagnosis for Mikulicz disease. ( 19451003 )	Shimizu M....Yoshiura K.	2009
10	F-18 FDG PET-CT findings in Mikulicz disease and systemic involvement of IgG4-related lesions. ( 19352281 )	Suga K....Takeuchi M.	2009
11	Diffuse periairway thickening in patients with Mikulicz disease. ( 18728553 )	Sakashita A....Ohno Y.	2008
12	Mikulicz disease of a minor salivary gland. ( 280669 )	Clark P.M....Gamble J.W.	1978
13	Mikulicz disease and subsequent lupus erythematosus development. ( 576964 )	Romero R.W....Ichinose H.	1977
14	Malignant lymphoma of parotid associated with Mikulicz disease (benign lymphoepithelial lesion). ( 4943296 )	Azzopardi J.G....Evans D.J.	1971
15	The parotid gland in Mikulicz disease and Sjogren's syndrome. ( 13713214 )	Hemenway W.G.	1960
16	The parotid gland in Mikulicz disease and Sjogren's syndrome. ( 13713215 )	Hemenway W.G.	1960
17	Mikulicz' disease: report of a case of one week's duration. ( 14908801 )	CRUICKSHANK B.	1952
18	Benign lymphoepithelial lesion of the parotid gland adenolymphoma, chronic inflammation, lymphoepithelioma, lymphocytic tumor, Mikulicz disease. ( 12998015 )	GODWIN J.T.	1952
19	Mikulicz' disease and Mikulicz' syndrome. ( 18119668 )	Heath P.	1949
20	A CASE OF MIKULICZ' DISEASE. ( 18168915 )	Owen H.B....Hennessey R.S.	1930
21	LYMPHOID HYPERPLASIA OF LACRYMAL AND SALIVARY GLANDS: MIKULICZ' DISEASE. ( 17865927 )	Smith J.F....Bump W.S.	1928

Sources

Genes for Mikulicz Disease

Genes related to Mikulicz Disease (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	IL21	Interleukin 21	Protein Coding	21.54	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	SMUG1	Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1	Protein Coding	14.87	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	PTGDR2	Prostaglandin D2 Receptor 2	Protein Coding	14.74	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	AQP5	Aquaporin 5	Protein Coding	14.59	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	PHB	Prohibitin	Protein Coding	14.54	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	AICDA	Activation Induced Cytidine Deaminase	Protein Coding	14.3	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

Sources

Variations for Mikulicz Disease

Sources

Expression for Mikulicz Disease

Search GEO for disease gene expression data for Mikulicz Disease.

Sources

Pathways for Mikulicz Disease

Sources

GO Terms for Mikulicz Disease

Biological processes related to Mikulicz Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of G-protein coupled receptor protein signaling pathway	GO:0045745	8.62	PHB PTGDR2

Sources

Sources for Mikulicz Disease

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia