MCID: MLR009
MIFTS: 33

Miliaria

Categories: Endocrine diseases, Skin diseases

Aliases & Classifications for Miliaria

MalaCards integrated aliases for Miliaria:

Name: Miliaria 12 15 17 70
Eccrine Miliaria 12
Sweat Rash 12
Heat Rash 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1382
MeSH 44 D008883
NCIt 50 C34820
SNOMED-CT 67 63951004
ICD10 32 L74.3
UMLS 70 C0026113

Summaries for Miliaria

Disease Ontology : 12 A sweat gland disease that is characterized by blocked eccrine sweat glands and ducts.

MalaCards based summary : Miliaria, also known as eccrine miliaria, is related to miliaria rubra and pseudohypoaldosteronism, and has symptoms including exanthema An important gene associated with Miliaria is SCNN1G (Sodium Channel Epithelial 1 Subunit Gamma), and among its related pathways/superpathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Neuropathic Pain-Signaling in Dorsal Horn Neurons. Affiliated tissues include skin, eye and thyroid.

Wikipedia : 73 Miliaria, also called "sweat rash", is a skin disease marked by small and itchy rashes due to sweat... more...

Related Diseases for Miliaria

Diseases related to Miliaria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 88)
# Related Disease Score Top Affiliating Genes
1 miliaria rubra 31.4 SCNN1G SCNN1B SCNN1A KRTAP13-1 CFTR ASIC3
2 pseudohypoaldosteronism 29.8 SCNN1G SCNN1B SCNN1A CFTR
3 metabolic acidosis 29.8 SCNN1G SCNN1B SCNN1A
4 miliaria crystallina 11.4
5 miliaria profunda 11.4
6 miliaria pustulosa 11.3
7 fox-fordyce disease 11.2
8 anhidrosis 10.3
9 exanthem 10.2
10 impetigo 10.2
11 bullous impetigo 10.1
12 pseudohypoaldosteronism, type i, autosomal dominant 10.1 SCNN1G SCNN1B SCNN1A
13 decubitus ulcer 10.1 IL1A ASIC3
14 bartter syndrome, type 2, antenatal 10.1 SCNN1G SCNN1B SCNN1A
15 renal tubular transport disease 10.1 SCNN1G SCNN1B SCNN1A
16 pseudohypoaldosteronism, type i, autosomal recessive 10.1 SCNN1G SCNN1B SCNN1A
17 bronchiectasis with or without elevated sweat chloride 1 10.0 SCNN1B CFTR
18 pertussis 10.0
19 skin disease 10.0
20 lung disease 10.0
21 pneumatosis cystoides intestinalis 9.9 SI MGAM
22 barre-lieou syndrome 9.9 SI MGAM
23 hirata disease 9.9 SI MGAM
24 postgastrectomy syndrome 9.9 SI MGAM
25 acute laryngopharyngitis 9.9 SI MGAM
26 trigonitis 9.9 SI MGAM
27 chicken egg allergy 9.9 SI MGAM
28 functional gastric disease 9.9 SI MGAM
29 sucrase-isomaltase deficiency, congenital 9.9 SI MGAM
30 parkinson disease 17 9.9 SI MGAM
31 nasopharyngitis 9.9 SI MGAM
32 glycogen storage disease ii 9.9 SI MGAM
33 typhoid fever 9.9 IL1A CFTR
34 glycogen storage disease iii 9.9 SI MGAM
35 diabetes mellitus, ketosis-prone 9.9 SI MGAM
36 mucopolysaccharidosis, type vi 9.9 SI MGAM
37 mucopolysaccharidosis, type ii 9.8 SI MGAM
38 mucopolysaccharidosis iv 9.8 SI MGAM
39 ocular motor apraxia 9.8
40 pulmonary alveolar microlithiasis 9.8
41 dermatitis, atopic 9.8
42 myelodysplastic syndrome 9.8
43 congenital hypothyroidism 9.8
44 chorioamnionitis 9.8
45 autosomal recessive congenital ichthyosis 9.8
46 meningocele 9.8
47 pyelonephritis 9.8
48 allergic disease 9.8
49 neutropenia 9.8
50 cholestasis 9.8

Graphical network of the top 20 diseases related to Miliaria:



Diseases related to Miliaria

Symptoms & Phenotypes for Miliaria

UMLS symptoms related to Miliaria:


exanthema

Drugs & Therapeutics for Miliaria

Search Clinical Trials , NIH Clinical Center for Miliaria

Genetic Tests for Miliaria

Anatomical Context for Miliaria

MalaCards organs/tissues related to Miliaria:

40
Skin, Eye, Thyroid, Pituitary

Publications for Miliaria

Articles related to Miliaria:

(show top 50) (show all 221)
# Title Authors PMID Year
1
Localized mid face miliaria in a healthcare worker due to N95 respirator use: A case report and management strategies. 61
33492777 2021
2
Cutaneous and histopathological features of coronavirus disease 2019 in pediatrics: A review article. 61
33210417 2021
3
Isolated hypohidrosis: pathogenesis and treatment. 61
33262099 2020
4
Occupational skin disease in mining: an Australian case series. 61
33372583 2020
5
Pattern of pediatric skin disorders in Murtala Muhammad Specialist Hospital Kano, Nigeria. 61
33525278 2020
6
Sprinkled water drops on the skin in newborns: congenital miliaria crystallina. 61
32312743 2020
7
Localized mid-face miliaria as a consequence of filtering face piece respirator use during the COVID-19 pandemic. 61
32386442 2020
8
Case of miliaria rubra histologically showing neutrophilic eccrine hidradenitis due to hyperhidrosis induced by a catecholamine-producing neuroblastoma. 61
31912533 2020
9
Why does sweat lead to the development of itch in atopic dermatitis? 61
31152459 2019
10
Atypical Presentation of Sweat Dermatitis with Review of Literature. 61
31807452 2019
11
Granulomatous Variant of Giant Centrifugal Miliaria Profunda in a Hypothyroid Infant: A Case Report. 61
31544077 2019
12
Miliaria crystallina secondary to herbal remedies-induced toxic epidermal necrolysis: A case report. 61
31197923 2019
13
Integrated Transcriptomic and Proteomic Analysis of Human Eccrine Sweat Glands Identifies Missing and Novel Proteins. 61
33451522 2019
14
Integrated Transcriptomic and Proteomic Analysis of Human Eccrine Sweat Glands Identifies Missing and Novel Proteins. 61
30979791 2019
15
Gradient-based 3D skin roughness rendering from an in-vivo skin image for dynamic haptic palpation. 61
30604497 2019
16
Common Neonatal Rashes. 61
30653638 2019
17
A cross-sectional study of sweat-induced dermatitis during a South Indian summer: a glimpse of sweat gland-mediated cutaneous inflammation. 61
29896898 2019
18
Energy crops affecting farmland birds in Central Europe: insights from a miscanthus-dominated landscape. 61
30636777 2019
19
[Axillary and perimamillary Fox-Fordyce disease (apocrine miliaria) in a 19-year-old woman]. 61
29110043 2018
20
Neutrophilic superficial eccrine ductitis: Proposal of a new disease concept. 61
29314202 2018
21
The increasing relevance of biofilms in common dermatological conditions. 61
28749746 2018
22
Pegylated liposomal doxorubicin-induced miliaria crystallina and lichenoid follicular eruption. 61
28513486 2018
23
[Multifocal tuberculosis revealed by pancytopenia: about a case]. 61
31011393 2018
24
[Widespread miliaria crystallina: about a case]. 61
30344853 2018
25
Expression of epithelial sodium channel (ENaC) and CFTR in the human epidermis and epidermal appendages. 61
28130590 2017
26
Foxc1 Ablated Mice Are Anhidrotic and Recapitulate Features of Human Miliaria Sweat Retention Disorder. 61
27592801 2017
27
Professional interest in dermatopathology of Stanisław Ostrowski - the only one State Polish President among physicians. 61
29517196 2017
28
Inflammatory and glandular skin disease in pregnancy. 61
27265071 2016
29
Hypohidrosis in Individuals with Exertional Heat Injury: A Prospective Open Cohort Study. 61
26402230 2016
30
[Widespread miliaria crystalline]. 61
28292125 2016
31
The effects of the El Niño Southern Oscillation on skin and skin-related diseases: a message from the International Society of Dermatology Climate Change Task Force. 61
26471012 2015
32
Miliaria crystallina: relevance in patients with hemato-oncological febrile neutropenia. 61
26611484 2015
33
The Infectious and Noninfectious Dermatological Consequences of Flooding: A Field Manual for the Responding Provider. 61
26159354 2015
34
The evaluation and management of heat injuries in an intensive care unit. 61
26321809 2015
35
Dermal and Ophthalmic Findings in Pseudohypoaldosteronism. 61
26316441 2015
36
Histopathological and immunohistochemical features of nodular podoconiosis. 61
25401490 2015
37
Neonatal pustular dermatosis: an overview. 61
25814724 2015
38
In vivo imaging of miliaria profunda using high-definition optical coherence tomography: diagnosis, pathogenesis, and treatment. 61
25390622 2015
39
Bull's-eye pattern in miliaria rubra. 61
23808709 2014
40
Hypernatremia-related miliaria crystallina. 61
24263814 2014
41
[Crystalline miliaria]. 61
24889747 2014
42
Ocular and skin manifestations in systemic pseudohypoaldosteronism. 61
24654255 2014
43
Dermatologic conditions in teenage adolescents in Nigeria. 61
24966708 2014
44
A cross-sectional prospective study of cutaneous lesions in newborn. 61
24575304 2014
45
Widespread miliaria crystallina in a newborn with hypernatremic dehydration. 61
23252502 2013
46
Granulomatous variant of giant centrifugal miliaria profunda. 61
22276567 2013
47
The oldest new finding in atopic dermatitis: subclinical miliaria as an origin. 61
23715198 2013
48
Skin conditions: common skin rashes in infants. 61
23600337 2013
49
Congenital miliaria crystallina - A diagnostic dilemma. 61
24532912 2012
50
[Summer in the intensive care unit. Why did the patient get blisters on the abdomen? Miliaria cristallina]. 61
23156858 2012

Variations for Miliaria

Expression for Miliaria

Search GEO for disease gene expression data for Miliaria.

Pathways for Miliaria

Pathways related to Miliaria according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.98 SCNN1G SCNN1B SCNN1A CFTR ASIC3
2
Show member pathways
12.3 SCNN1G SCNN1B SCNN1A CFTR
3
Show member pathways
12.12 SCNN1G SCNN1B SCNN1A ASIC3
4
Show member pathways
11.71 SCNN1G SCNN1B SCNN1A
5 11.15 SI MGAM
6 11 SCNN1G SCNN1B SCNN1A
7 10.79 SCNN1G SCNN1B SCNN1A
8 10.57 SCNN1G SCNN1B SCNN1A CFTR ASIC3
9 10.37 SCNN1G SCNN1B SCNN1A CFTR
10 10.32 SI MGAM

GO Terms for Miliaria

Cellular components related to Miliaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.65 SCNN1G SCNN1B SCNN1A CFTR ASIC3
2 plasma membrane protein complex GO:0098797 9.16 SCNN1G SCNN1B
3 sodium channel complex GO:0034706 9.13 SCNN1G SCNN1B SCNN1A
4 apical plasma membrane GO:0016324 9.1 SI SCNN1G SCNN1B SCNN1A MGAM CFTR

Biological processes related to Miliaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ion transport GO:0006811 9.83 SCNN1G SCNN1B SCNN1A CFTR ASIC3
2 ion transmembrane transport GO:0034220 9.76 SCNN1G SCNN1B SCNN1A ASIC3
3 sodium ion transport GO:0006814 9.56 SCNN1G SCNN1B SCNN1A ASIC3
4 sensory perception of taste GO:0050909 9.5 SCNN1G SCNN1B SCNN1A
5 excretion GO:0007588 9.48 SCNN1G SCNN1B
6 sodium ion transmembrane transport GO:0035725 9.46 SCNN1G SCNN1B SCNN1A ASIC3
7 polysaccharide digestion GO:0044245 9.4 SI MGAM
8 cellular response to aldosterone GO:1904045 9.37 SCNN1G SCNN1B
9 sodium ion homeostasis GO:0055078 9.13 SCNN1G SCNN1B SCNN1A
10 multicellular organismal water homeostasis GO:0050891 8.92 SCNN1G SCNN1B SCNN1A CFTR

Molecular functions related to Miliaria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 WW domain binding GO:0050699 9.33 SCNN1G SCNN1B SCNN1A
2 hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 9.32 SI MGAM
3 alpha-1,4-glucosidase activity GO:0004558 9.26 SI MGAM
4 sodium channel activity GO:0005272 9.26 SCNN1G SCNN1B SCNN1A ASIC3
5 ligand-gated sodium channel activity GO:0015280 8.92 SCNN1G SCNN1B SCNN1A ASIC3

Sources for Miliaria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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