Aliases & Classifications for Miliaria Rubra

MalaCards integrated aliases for Miliaria Rubra:

Name: Miliaria Rubra 12 15 73
Miliaria Crystallina 12 73
Miliaria 44 73
Prickly Heat - Miliaria 12
Sudamina 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11153
ICD9CM 35 705.1
MeSH 44 D008883

Summaries for Miliaria Rubra

MalaCards based summary : Miliaria Rubra, also known as miliaria crystallina, is related to miliaria and pseudohypoaldosteronism, and has symptoms including exanthema An important gene associated with Miliaria Rubra is TSPAN7 (Tetraspanin 7), and among its related pathways/superpathways are CFTR-dependent regulation of ion channels in Airway Epithelium (norm and CF) and NO-dependent CFTR activation (normal and CF). The drugs Vaccines and Tetracycline have been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Related Diseases for Miliaria Rubra

Diseases related to Miliaria Rubra via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)
# Related Disease Score Top Affiliating Genes
1 miliaria 28.5 CFTR SCNN1G SNCA TSPAN7
2 pseudohypoaldosteronism 10.2
3 impetigo 10.2
4 bullous impetigo 10.2
5 skin disease 10.0
6 meningocele 10.0
7 hypohidrosis 10.0
8 anhidrosis 10.0
9 thrombocytosis 10.0
10 type i 10.0
11 idiopathic bronchiectasis 9.9 CFTR SCNN1G
12 pulmonary edema 9.8 CFTR IL10
13 liddle syndrome 9.8 CFTR SCNN1G
14 aspergillosis 9.8 CFTR IL10
15 gallbladder disease 9.8 CFTR IL10
16 bronchiectasis 9.7 CFTR SCNN1G
17 respiratory system disease 9.7 CFTR IL10
18 aging 9.3 IL10 SNCA
19 lung disease 9.2 CFTR IL10
20 nervous system disease 9.2 IL10 SNCA

Graphical network of the top 20 diseases related to Miliaria Rubra:



Diseases related to Miliaria Rubra

Symptoms & Phenotypes for Miliaria Rubra

UMLS symptoms related to Miliaria Rubra:


exanthema

GenomeRNAi Phenotypes related to Miliaria Rubra according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.53 CFTR IL10 SCNN1G SNCA
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.53 CFTR IL10 SCNN1G SNCA

MGI Mouse Phenotypes related to Miliaria Rubra:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.55 CFTR IL10 SCNN1G SNCA TSPAN7
2 digestive/alimentary MP:0005381 9.26 CFTR IL10 SCNN1G SNCA
3 normal MP:0002873 8.92 CFTR IL10 SCNN1G SNCA

Drugs & Therapeutics for Miliaria Rubra

Drugs for Miliaria Rubra (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 3,Phase 2
2
Tetracycline Approved, Vet_approved Phase 2 60-54-8 5353990
3 Anti-Bacterial Agents Phase 2
4 Anti-Infective Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Safety, Tolerability And On-Body Temperature Of A Disposable Heatwrap Device For The Lower Back Completed NCT01055262 Phase 3
2 Immunogenicity and Safety Study of PriorixTetraâ„¢ When Co-administered With Conjugated MenC Vaccine in Healthy Children Completed NCT01506193 Phase 3
3 Immunogenicity & Safety Study of GSK Biologicals' 208136 Vaccine Formulated With New Measles and Rubella Working Seeds Completed NCT00892775 Phase 2

Search NIH Clinical Center for Miliaria Rubra

Cochrane evidence based reviews: miliaria

Genetic Tests for Miliaria Rubra

Anatomical Context for Miliaria Rubra

MalaCards organs/tissues related to Miliaria Rubra:

41
Skin, Eye

Publications for Miliaria Rubra

Articles related to Miliaria Rubra:

(show all 22)
# Title Authors Year
1
Bull's-eye pattern in miliaria rubra. ( 23808709 )
2013
2
Miliaria rubra and thrombocytosis in pseudohypoaldosteronism: case report. ( 22150373 )
2012
3
Newborn with pseudohypoaldosteronism and miliaria rubra. ( 17184247 )
2006
4
Pustular miliaria rubra: a specific cutaneous finding of type I pseudohypoaldosteronism. ( 12220275 )
2002
5
Miliaria rubra of the lower limbs in underground miners. ( 10994246 )
2000
6
Investigation into the environmental factors associated with the incidence of skin disease following an outbreak of Miliaria rubra at a coal mine. ( 1421332 )
1992
7
Deletion 3q27----3qter in an infant with mild dysmorphism, parietal meningocele, and neonatal miliaria rubra-like lesions. ( 2793176 )
1989
8
Nonconventional remission of miliaria rubra during heat acclimation: a case report. ( 3140055 )
1988
9
Heat intolerance as a function of percent of body surface involved with miliaria rubra. ( 7435594 )
1980
10
Persistence of impaired heat tolerance from artificially induced miliaria rubra. ( 7435593 )
1980
11
The pathogenesis of miliaria rubra. Role of the resident microflora. ( 698101 )
1978
12
The effect of pretreatment of skin on artificially induced miliaria rubra and hypohidrosis. ( 4926865 )
1971
13
SUPPRESSION OF MILIARIA RUBRA (PRICKLY HEAT) BY A TOPICAL ANTICHOLINERGIC AGENT. ( 14139556 )
1964
14
Miliaria rubra, a manifestation of staphylococcal disease. ( 14467655 )
1962
15
Studies on miliaria rubra. ( 14419196 )
1960
16
Neomycin lotion in the treatment of miliaria rubra (prickly heat). ( 13337742 )
1956
17
The treatment of miliaria rubra with neomycin lotion. ( 14381671 )
1955
18
Generalized miliaria rubra associated with abnormal vitamin A metabolism. ( 14867847 )
1951
19
Comments to "The etiology of poral closure, an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. By John P. O'Brien, M. D.". ( 15437055 )
1950
20
The etiology of poral closure; an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. I. An historical review of the causation of miliaria. ( 15437051 )
1950
21
The etiology of poral closure. II. The role of staphylococcal infection in miliaria rubra and bullous impetigo. ( 15437052 )
1950
22
A study of miliaria rubra, tropical anhidrosis and anhidrotic asthenia. ( 20242508 )
1947

Variations for Miliaria Rubra

Expression for Miliaria Rubra

Search GEO for disease gene expression data for Miliaria Rubra.

Pathways for Miliaria Rubra

Pathways related to Miliaria Rubra according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.5 CFTR SCNN1G
2 9.74 CFTR SCNN1G

GO Terms for Miliaria Rubra

Biological processes related to Miliaria Rubra according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.26 IL10 SNCA
2 aging GO:0007568 9.16 IL10 SNCA
3 membrane organization GO:0061024 8.96 CFTR SNCA
4 multicellular organismal water homeostasis GO:0050891 8.62 CFTR SCNN1G

Sources for Miliaria Rubra

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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