Aliases & Classifications for Miliaria Rubra

MalaCards integrated aliases for Miliaria Rubra:

Name: Miliaria Rubra 12 15 73
Miliaria Crystallina 12 73
Miliaria 44 73
Prickly Heat - Miliaria 12
Sudamina 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11153
ICD9CM 35 705.1
MeSH 44 D008883
SNOMED-CT 68 44279002 72658003

Summaries for Miliaria Rubra

MalaCards based summary : Miliaria Rubra, also known as miliaria crystallina, is related to miliaria and fox-fordyce disease, and has symptoms including exanthema An important gene associated with Miliaria Rubra is TSPAN7 (Tetraspanin 7), and among its related pathways/superpathways are CFTR-dependent regulation of ion channels in Airway Epithelium (norm and CF) and NO-dependent CFTR activation (normal and CF). The drugs Vaccines and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and lung, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Related Diseases for Miliaria Rubra

Diseases related to Miliaria Rubra via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 31)
# Related Disease Score Top Affiliating Genes
1 miliaria 30.4 TSPAN7 SNCA SCNN1G CFTR
2 fox-fordyce disease 12.1
3 pseudohypoaldosteronism 10.4
4 impetigo 10.4
5 bullous impetigo 10.4
6 neutropenia 10.3
7 chorioamnionitis 10.3
8 ritter's disease 10.3
9 skin disease 10.1
10 meningocele 10.1
11 hypohidrosis 10.1
12 anhidrosis 10.1
13 thrombocytosis 10.1
14 idiopathic bronchiectasis 10.0 SCNN1G CFTR
15 bronchiectasis 10.0 SCNN1G CFTR
16 autoimmune pancreatitis 10.0 IL10 CFTR
17 liddle syndrome 1 10.0 SCNN1G CFTR
18 pulmonary edema 9.9 IL10 CFTR
19 aspergillosis 9.9 IL10 CFTR
20 gallbladder disease 9.9 IL10 CFTR
21 dermatitis, atopic 9.9
22 leukemia 9.9
23 cholinergic urticaria 9.9
24 urticaria 9.9
25 dermatitis 9.9
26 acute pancreatitis 9.9 IL10 CFTR
27 respiratory system disease 9.9 IL10 CFTR
28 bacterial infectious disease 9.9 IL10 CFTR
29 aging 9.8 SNCA IL10
30 lung disease 9.8 IL10 CFTR
31 nervous system disease 9.8 SNCA IL10

Graphical network of the top 20 diseases related to Miliaria Rubra:



Diseases related to Miliaria Rubra

Symptoms & Phenotypes for Miliaria Rubra

UMLS symptoms related to Miliaria Rubra:


exanthema

GenomeRNAi Phenotypes related to Miliaria Rubra according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.53 CFTR IL10 SCNN1G SNCA
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.53 CFTR IL10 SCNN1G SNCA

MGI Mouse Phenotypes related to Miliaria Rubra:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.55 CFTR IL10 SCNN1G SNCA TSPAN7
2 digestive/alimentary MP:0005381 9.26 CFTR IL10 SCNN1G SNCA
3 normal MP:0002873 8.92 CFTR IL10 SCNN1G SNCA

Drugs & Therapeutics for Miliaria Rubra

Drugs for Miliaria Rubra (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 3,Phase 1,Phase 2
2 Immunologic Factors Phase 3,Phase 1,Phase 2
3
Tetracycline Approved, Vet_approved Phase 1, Phase 2 60-54-8 5353990
4 Anti-Bacterial Agents Phase 1, Phase 2
5 Anti-Infective Agents Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Safety, Tolerability And On-Body Temperature Of A Disposable Heatwrap Device For The Lower Back Completed NCT01055262 Phase 3
2 Immunogenicity and Safety Study of PriorixTetraâ„¢ When Co-administered With Conjugated MenC Vaccine in Healthy Children Completed NCT01506193 Phase 3
3 Immunogenicity & Safety Study of GSK Biologicals' 208136 Vaccine Formulated With New Measles and Rubella Working Seeds Completed NCT00892775 Phase 1, Phase 2

Search NIH Clinical Center for Miliaria Rubra

Cochrane evidence based reviews: miliaria

Genetic Tests for Miliaria Rubra

Anatomical Context for Miliaria Rubra

MalaCards organs/tissues related to Miliaria Rubra:

41
Skin, Eye, Lung

Publications for Miliaria Rubra

Articles related to Miliaria Rubra:

(show all 24)
# Title Authors Year
1
Miliaria crystallina: relevance in patients with hemato-oncological febrile neutropenia. ( 26611484 )
2015
2
Bull's-eye pattern in miliaria rubra. ( 23808709 )
2013
3
Miliaria rubra and thrombocytosis in pseudohypoaldosteronism: case report. ( 22150373 )
2012
4
Newborn with pseudohypoaldosteronism and miliaria rubra. ( 17184247 )
2006
5
Miliaria crystallina complicating staphylococcal scalded skin syndrome. ( 14709532 )
2004
6
Pustular miliaria rubra: a specific cutaneous finding of type I pseudohypoaldosteronism. ( 12220275 )
2002
7
Miliaria rubra of the lower limbs in underground miners. ( 10994246 )
2000
8
Investigation into the environmental factors associated with the incidence of skin disease following an outbreak of Miliaria rubra at a coal mine. ( 1421332 )
1992
9
Deletion 3q27----3qter in an infant with mild dysmorphism, parietal meningocele, and neonatal miliaria rubra-like lesions. ( 2793176 )
1989
10
Nonconventional remission of miliaria rubra during heat acclimation: a case report. ( 3140055 )
1988
11
Heat intolerance as a function of percent of body surface involved with miliaria rubra. ( 7435594 )
1980
12
Persistence of impaired heat tolerance from artificially induced miliaria rubra. ( 7435593 )
1980
13
The pathogenesis of miliaria rubra. Role of the resident microflora. ( 698101 )
1978
14
The effect of pretreatment of skin on artificially induced miliaria rubra and hypohidrosis. ( 4926865 )
1971
15
SUPPRESSION OF MILIARIA RUBRA (PRICKLY HEAT) BY A TOPICAL ANTICHOLINERGIC AGENT. ( 14139556 )
1964
16
Miliaria rubra, a manifestation of staphylococcal disease. ( 14467655 )
1962
17
Studies on miliaria rubra. ( 14419196 )
1960
18
Neomycin lotion in the treatment of miliaria rubra (prickly heat). ( 13337742 )
1956
19
The treatment of miliaria rubra with neomycin lotion. ( 14381671 )
1955
20
Generalized miliaria rubra associated with abnormal vitamin A metabolism. ( 14867847 )
1951
21
Comments to "The etiology of poral closure, an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. By John P. O'Brien, M. D.". ( 15437055 )
1950
22
The etiology of poral closure; an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. I. An historical review of the causation of miliaria. ( 15437051 )
1950
23
The etiology of poral closure. II. The role of staphylococcal infection in miliaria rubra and bullous impetigo. ( 15437052 )
1950
24
A study of miliaria rubra, tropical anhidrosis and anhidrotic asthenia. ( 20242508 )
1947

Variations for Miliaria Rubra

Expression for Miliaria Rubra

Search GEO for disease gene expression data for Miliaria Rubra.

Pathways for Miliaria Rubra

Pathways related to Miliaria Rubra according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.5 CFTR SCNN1G
2 9.74 CFTR SCNN1G

GO Terms for Miliaria Rubra

Biological processes related to Miliaria Rubra according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.26 IL10 SNCA
2 response to lipopolysaccharide GO:0032496 9.16 IL10 SNCA
3 membrane organization GO:0061024 8.96 CFTR SNCA
4 multicellular organismal water homeostasis GO:0050891 8.62 CFTR SCNN1G

Sources for Miliaria Rubra

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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