MCID: MNS002
MIFTS: 19

Mini Stroke

Categories: Blood diseases, Eye diseases, Neuronal diseases

Aliases & Classifications for Mini Stroke

MalaCards integrated aliases for Mini Stroke:

Name: Mini Stroke 53 6
Mini-Stroke 71

Classifications:



External Ids:

UMLS 71 C1456577

Summaries for Mini Stroke

NINDS : 53 A transient ischemic attack (TIA) is a transient stroke that lasts only a few minutes. It occurs when the blood supply to part of the brain is briefly interrupted. TIA symptoms, which usually occur suddenly, are similar to those of stroke but do not last as long. Most symptoms of a TIA disappear within an hour, although they may persist for up to 24 hours. Symptoms can include: numbness or weakness in the face, arm, or leg, especially on one side of the body; confusion or difficulty in talking or understanding speech; trouble seeing in one or both eyes; and difficulty with walking, dizziness, or loss of balance and coordination.

MalaCards based summary : Mini Stroke, also known as mini-stroke, is related to stroke, ischemic and transient cerebral ischemia. An important gene associated with Mini Stroke is NOTCH3 (Notch Receptor 3). The drugs Nicotine and Coumarin have been mentioned in the context of this disorder. Affiliated tissues include retina, spinal cord and cortex.

Wikipedia : 74 A transient ischemic attack (TIA), commonly known as a mini-stroke, is a brief episode of neurological... more...

Related Diseases for Mini Stroke

Diseases related to Mini Stroke via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 stroke, ischemic 11.3
2 transient cerebral ischemia 11.1
3 fibromuscular dysplasia 11.1
4 carotid artery disease 11.1
5 cerebrovascular disease 11.1

Graphical network of the top 20 diseases related to Mini Stroke:



Diseases related to Mini Stroke

Symptoms & Phenotypes for Mini Stroke

Drugs & Therapeutics for Mini Stroke

Drugs for Mini Stroke (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nicotine Approved 54-11-5 942 89594
2
Coumarin Experimental 91-64-5 323
3 Hydroxymethylglutaryl-CoA Reductase Inhibitors
4 Platelet Aggregation Inhibitors
5 Anticoagulants

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Intensified Secondary Prevention Intending a Reduction of Recurrent Events in TIA and Minor Stroke Patients (INSPiRE-TMS) A Randomized Trial Comparing a Patient Centered Support Program Versus Conventional Car Completed NCT01586702

Search NIH Clinical Center for Mini Stroke

Genetic Tests for Mini Stroke

Anatomical Context for Mini Stroke

MalaCards organs/tissues related to Mini Stroke:

40
Retina, Spinal Cord, Cortex, Amygdala

Publications for Mini Stroke

Articles related to Mini Stroke:

(show all 28)
# Title Authors PMID Year
1
Molecular Basis of Sex Difference in Neuroprotection induced by Hypoxia Preconditioning in Zebrafish. 61
32862360 2020
2
Inconsistent Classification of Mild Stroke and Implications on Health Services Delivery. 61
32001257 2020
3
Cortical Transplantation of Brain-Mimetic Glycosaminoglycan Scaffolds and Neural Progenitor Cells Promotes Vascular Regeneration and Functional Recovery after Ischemic Stroke in Mice. 61
31977165 2020
4
Modelling mortality and discharge of hospitalized stroke patients using a phase-type recovery model. 61
29717401 2019
5
A Readability Analysis of Online Cardiovascular Disease-Related Health Education Materials. 61
31049489 2019
6
Self-reported history of stroke and long-term living conditions near air pollution sources: results of a national epidemiological study in Lebanon. 61
29460147 2018
7
Establishing research priorities relating to the long-term impact of TIA and minor stroke through stakeholder-centred consensus. 61
29416879 2018
8
High-speed photoacoustic microscopy of mouse cortical microhemodynamics. 61
28009098 2017
9
[After a mini-stroke special care is a responsibility]. 61
27221426 2016
10
Internet-based information-seeking behavior for transient ischemic attack. 61
26282685 2015
11
Hippocampal ischemia causes deficits in local field potential and synaptic plasticity. 61
26445570 2015
12
Endothelin-1-induced mini-stroke in the dorsal hippocampus or lateral amygdala results in deficits in learning and memory. 61
26445569 2015
13
Why every mini-stroke must be treated as an emergency. 61
24844498 2014
14
Mini-stroke: what should you do? The symptoms may be short-lived, but you should take them every bit as seriously as you would a true stroke. 61
24941467 2014
15
Delay in seeking medical help following Transient Ischemic Attack (TIA) or "mini-stroke": a qualitative study. 61
25137185 2014
16
It is not a 'mini'-stroke, it is a call to action. 61
24001960 2013
17
Determination of geographic variance in stroke prevalence using Internet search engine analytics. 61
21631220 2011
18
Stress and corticosterone enhance cognitive recovery from hippocampal stroke in rats. 61
19607880 2009
19
An examination of economic outcomes associated with misdiagnosis or undertreatment of TIA. 61
19601692 2009
20
Know the signs of a mini-stroke. A transient ischemic attack (TIA) can mean that you have an increased chance of having a full-fledged stroke, but there are steps you can take. 61
19350732 2009
21
Selective lesion of medial septal cholinergic neurons followed by a mini-stroke impairs spatial learning in rats. 61
18936927 2009
22
Dementia literacy: recognition and beliefs on dementia of the Australian public. 61
19118808 2009
23
Enhanced cell death and learning deficits after a mini-stroke in aged hippocampus. 61
17561312 2008
24
High blood pressure knowledge among primary care patients with known hypertension: a North Carolina Family Medicine Research Network (NC-FM-RN) study. 61
18612056 2008
25
A modified mini-stroke model with region-directed reperfusion in rat cortex. 61
18073774 2008
26
Enhanced cell death in hippocampus and emergence of cognitive impairments following a localized mini-stroke in hippocampus if preceded by a previous episode of acute stress. 61
18412637 2008
27
I had what my doctor called a mini-stroke. After an extensive evaluation from several other doctors, he concluded that I have a hole in my heart. He called it a PFO. He said I was born with it, but thought it should probably be closed now. What do you think? 61
16252359 2005
28
Treating a "mini-stroke" to prevent a "major" stroke. 61
16247865 2005

Variations for Mini Stroke

ClinVar genetic disease variations for Mini Stroke:

6
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 NOTCH3 NM_000435.3(NOTCH3):c.457C>T (p.Arg153Cys) SNV Pathogenic 208501 rs797045014 19:15302993-15302993 19:15192182-15192182
2 NOTCH3 NM_000435.3(NOTCH3):c.1450T>G (p.Cys484Gly) SNV Likely pathogenic 523370 rs1555728965 19:15299088-15299088 19:15188277-15188277

Expression for Mini Stroke

Search GEO for disease gene expression data for Mini Stroke.

Pathways for Mini Stroke

GO Terms for Mini Stroke

Sources for Mini Stroke

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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