MCID: MTN002
MIFTS: 26

Mite Infestation

Categories: Infectious diseases

Aliases & Classifications for Mite Infestation

MalaCards integrated aliases for Mite Infestation:

Name: Mite Infestation 12 15
Mite Infestations 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7894
ICD10 33 B88.0 B88.9
ICD9CM 35 133 133.9
MeSH 44 D008924
SNOMED-CT 68 78166003
UMLS 73 C0026229

Summaries for Mite Infestation

Disease Ontology : 12 A parasitic ectoparasitic infectious disease that involves infestation of mites belonging to the family Sarcoptidae, Trombiculidae and Demodicidae.

MalaCards based summary : Mite Infestation, also known as mite infestations, is related to scabies and demodicidosis. An important gene associated with Mite Infestation is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator), and among its related pathways/superpathways is Pancreatic secretion. The drugs Ivermectin and Permethrin have been mentioned in the context of this disorder. Affiliated tissues include t cells.

Related Diseases for Mite Infestation

Diseases related to Mite Infestation via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 scabies 11.6
2 demodicidosis 11.4
3 trombiculiasis 11.3
4 dermatitis 10.4
5 west nile fever 10.0 DEFA1 DEFA3
6 rheumatoid arthritis 10.0
7 arthritis 10.0
8 leukemia 10.0
9 t-cell leukemia 10.0
10 mucormycosis 10.0
11 rosacea 10.0
12 blepharitis 10.0
13 bell's palsy 10.0 DEFA1 DEFA3
14 parasitic ectoparasitic infectious disease 9.9 AADACL3 DSCAML1
15 multidrug-resistant tuberculosis 9.8 DEFA1 DEFA3
16 norwegian scabies 9.7 AADACL3 ATP2A2

Graphical network of the top 20 diseases related to Mite Infestation:



Diseases related to Mite Infestation

Symptoms & Phenotypes for Mite Infestation

Drugs & Therapeutics for Mite Infestation

Drugs for Mite Infestation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ivermectin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 70288-86-7 6474909
2
Permethrin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 52645-53-1 40326
3
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
4 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
5 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Not Applicable
6
Malathion Approved, Investigational Phase 3 121-75-5 4004
7
Albendazole Approved, Vet_approved Phase 3,Not Applicable 54965-21-8 2082
8
Diethylcarbamazine Approved, Investigational, Vet_approved Phase 3,Not Applicable 90-89-1 3052
9 Cholinergic Agents Phase 3
10 Neurotransmitter Agents Phase 3
11 Cholinesterase Inhibitors Phase 3
12 Anthelmintics Phase 3,Not Applicable
13 Lipoxygenase Inhibitors Phase 3,Not Applicable
14 Antimitotic Agents Phase 3,Not Applicable
15 Antiprotozoal Agents Phase 3,Not Applicable
16 Dermatologic Agents Phase 3
17 Emollients Phase 3
18 Anti-Bacterial Agents Phase 3
19
Ethanol Approved Phase 2 64-17-5 702
20
Benzyl alcohol Approved Phase 2 100-51-6 244
21 Anesthetics, Local Phase 2
22 Central Nervous System Depressants Phase 2
23 Peripheral Nervous System Agents Phase 2
24 Anesthetics Phase 2
25 Pharmaceutical Solutions Phase 2
26 Liver Extracts Not Applicable

Interventional clinical trials:

(show all 22)
# Name Status NCT ID Phase Drugs
1 Azithromycin - Ivermectin Mass Drug Administration for Skin Disease Completed NCT02775617 Phase 4 Ivermectin;Azithromycin;Permethrin
2 Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children Unknown status NCT02407782 Phase 3 Ivermectin;Permethrin
3 P3 Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation Completed NCT02062060 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
4 Phase 3 Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation Completed NCT02060903 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
5 Bio-equivalence Study Comparing Permethrin Cream, 5% With Elimite in Patients With Active Scabies. Completed NCT02978508 Phase 3 Permethrin Cream, 5%;Elimite
6 A Study to Evaluate the Therapeutic Equivalence of Generic Permethrin Cream 5% to Elimite® in the Treatment of Scabies Completed NCT02572986 Phase 3 Permethrin
7 Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies Completed NCT02485717 Phase 3 spinosad topical suspension, 0.9%
8 Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies Completed NCT02485704 Phase 3 spinosad topical suspension, 0.9%
9 Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands Completed NCT03236168 Phase 3 Ivermectin;Permethrin 5%;Malathion Shampoo 0.5%
10 Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% in the Treatment of Scabies Active, not recruiting NCT03178942 Phase 3 Permethrin;Elimite 5% Cream
11 Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies Not yet recruiting NCT02841215 Phase 3 Ivermectin 200 µg/kg;Ivermectin 400 µg/kg
12 Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs ) Not yet recruiting NCT03676140 Phase 3 Albendazole on Day 1;Ivermectin on Day 1;Diethylcarbamazine on day 1;Azithromycin on Day 1;Azithromycin on Day 8
13 Ovicidal Efficacy and Safety of Abametapir Lotion 0.74% Administered for the Treatment of Head Lice Infestation Completed NCT02097485 Phase 2 Abametapir Lotion 0.74% w/w;Vehicle Lotion
14 Safety and PK Study of Ha44 Gel Under Maximal Use Conditions for Treatment of Head Lice Infestation Completed NCT01907490 Phase 2 Ha44 Gel
15 A Dose Ranging Vehicle Controlled Study to Determine the Safety and Efficacy of Permethrin Foam, 5% and Permethrin Foam, 4% for the Treatment of Scabies Completed NCT02094716 Phase 2 Permethrin Foam 4%;Permethrin Foam 5%;Vehicle Foam
16 Comparison of the Efficacy and Safety of Ivermectin to Permethrin Completed NCT00262418 Phase 2 Administration of ivermectin or permethrin
17 PCR (Polymerase Chain Reaction) Assay for Diagnosis of Sarcoptes Scabiei Completed NCT02254564
18 Veron Scabies Education and Eradication Program Completed NCT00604084 Not Applicable Ivermectin;Permethrin 5% lotion
19 Prevalence of RHD, Pyoderma and Scabies in Children in Fiji Completed NCT00284843
20 Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji Completed NCT03177993 Not Applicable 3 drug dose - IDA;3 drug dose - IDA with second dose of ivermectin;2 drug dose - DA
21 Streptococcal Infections in Fiji - Prevalence of Group A Streptococcal Pyoderma and Scabies in Infants in Fiji Completed NCT00436891
22 Evaluation of a Regional Healthy Skin Program in Remote Aboriginal Communities of Australia's Northern Territory Completed NCT00884728

Search NIH Clinical Center for Mite Infestation

Cochrane evidence based reviews: mite infestations

Genetic Tests for Mite Infestation

Anatomical Context for Mite Infestation

MalaCards organs/tissues related to Mite Infestation:

41
T Cells

Publications for Mite Infestation

Articles related to Mite Infestation:

(show top 50) (show all 106)
# Title Authors Year
1
Efficacy and safety of sarolaner in the treatment of canine ear mite infestation caused by Otodectes cynotis: a non-inferiority study. ( 29392787 )
2018
2
Crops Responses to Mite Infestation: It's Time to Look at Plant Tolerance to Meet the Farmers' Needs. ( 29740472 )
2018
3
Unraveling Rice Tolerance Mechanisms Against Schizotetranychus oryzae Mite Infestation. ( 30279693 )
2018
4
Essential oils: effects of application rate and modality on potential for combating northern fowl mite infestations. ( 29498419 )
2018
5
First Report of an Emaravirus Associated with Witches' Broom Disease and Eriophyid Mite Infestations of the Blue Palo Verde Tree in Arizona. ( 30125163 )
2018
6
Incidence of fur mite infestation in laboratory rodents. ( 28615846 )
2017
7
Role of Demodex mite infestation in rosacea: A systematic review and meta-analysis. ( 28711190 )
2017
8
Norwegian honey bees surviving Varroa destructor mite infestations by means of natural selection. ( 29085753 )
2017
9
Efficacy of lotilaner (Credelio™), a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp. ( 29089049 )
2017
10
Pruritic dermatitis caused by bird mite infestation. ( 26919364 )
2016
11
Megninia ginglymura feather mite infestation in a Hamburg poultry flock in the United Kingdom. ( 26914957 )
2016
12
Mange mite infestation in small ruminants in Ethiopia: Systematic review and meta-analysis. ( 26872931 )
2016
13
Evidence-based veterinary dermatology: a review of published studies of treatments for Otodectes cynotis (ear mite) infestation in cats. ( 27324289 )
2016
14
Developing food-grade coatings for dry-cured hams to protect against ham mite infestation. ( 26624793 )
2016
15
Intensively Cultivated Landscape and Varroa Mite Infestation Are Associated with Reduced Honey Bee Nutritional State. ( 27070422 )
2016
16
Physiological and Molecular Alterations Promoted by Schizotetranychus oryzae Mite Infestation in Rice Leaves. ( 26667653 )
2016
17
Efficacy of sarolaner, a novel oral isoxazoline, against two common mite infestations in dogs: Demodex spp. and Otodectes cynotis. ( 26971196 )
2016
18
ORIBATID MITE INFESTATION IN THE STORED CHINESE HERBAL MEDICINES. ( 26319834 )
2015
19
Dust mite infestation in cooking flour: experimental observations and practical recommendations. ( 26141033 )
2015
20
Blood-feeding ectoparasites as developmental stressors: Does corticosterone mediate effects of mite infestation on nestling growth, immunity and energy availability? ( 26055169 )
2015
21
KNEMIDOKOPTINID (EPIDERMOPTIDAE: KNEMIDOKOPTINAE) MITE INFESTATION IN WILD RED-CROWNED PARAKEETS (CYANORAMPHUS NOVAEZELANDIAE): CORRELATIONS BETWEEN MACROSCOPIC AND MICROSCOPIC FINDINGS. ( 25973626 )
2015
22
Molecular Prevalence of Acarapis Mite Infestations in Honey Bees in Korea. ( 26174825 )
2015
23
Case records of the Massachusetts General Hospital. Case 37-2014. A 35-year-old woman with suspected mite infestation. ( 25427115 )
2014
24
Evaluating troponin C from Psoroptes cuniculi as a diagnostic antigen for a dot-ELISA assay to diagnose mite infestations in rabbits. ( 24102446 )
2014
25
Demodex mite infestation of unknown significance in a patient with rhinocerebral mucormycosis due to Apophysomyces elegans species complex. ( 23475907 )
2013
26
Susceptibility and physiological responses of Jatropha curcas accessions to broad mite infestation. ( 23456604 )
2013
27
Severe ulceronecrotic dermatitis associated with mite infestation in the critically endangered Amargosa vole (Microtus californicus scirpensis). ( 23458565 )
2013
28
The role of onion-associated fungi in bulb mite infestation and damage to onion seedlings. ( 24242868 )
2013
29
Detection of group 2 Dermatophagoides pteronyssinus allergen for environmental monitoring of dust mite infestation. ( 23612077 )
2013
30
Bacillus oleronius and Demodex mite infestation in patients with chronic blepharitis. ( 22114987 )
2012
31
Demodex mite infestation in patients with and without rheumatoid arthritis. ( 22807020 )
2012
32
Genotypic variability and relationships between mite infestation levels, mite damage, grooming intensity, and removal of Varroa destructor mites in selected strains of worker honey bees (Apis mellifera L.). ( 22465569 )
2012
33
CFTR-deficiency renders mice highly susceptible to cutaneous symptoms during mite infestation. ( 21135815 )
2011
34
Dog ear mite infestation: a possible problem in public health system. ( 22808412 )
2011
35
Localized nasal cavity, sinus, and massive bilateral orbital involvement by human T cell leukemia virus 1 adult T cell lymphoma, with epidermal hypertrophy due to mite infestation. ( 21234251 )
2010
36
Ear mite infestation in four imported dogs from Thailand; a case report. ( 22808403 )
2010
37
Conditional mutualism between Allodynerus delphinalis (Hymenoptera: Vespidae) and Ensliniella parasitica (Astigmata: Winterschmidtiidae) may determine maximum parasitic mite infestation. ( 20388271 )
2010
38
Assessment of immune activation in mice before and after eradication of mite infestation. ( 19653944 )
2009
39
Localized seborrhoeic dermatitis with hyperhidrosis due to mite infestation in an Iranian cross-breed ram. ( 19579943 )
2009
40
Scrub-itch mite infestation in the endangered bridled nailtail wallaby. ( 19673851 )
2009
41
Dust mite infestation of flour samples. ( 19895625 )
2009
42
Mite infestations. ( 19580577 )
2009
43
Use of selamectin for the treatment of psoroptic and sarcoptic mite infestation in rabbits. ( 17222235 )
2007
44
Images in clinical medicine. Bird-mite infestation. ( 16625011 )
2006
45
Efficacy of topical administration of eprinomectin for treatment of ear mite infestation in six rabbits. ( 16238814 )
2005
46
Current trends in the treatment of Sarcoptes, Cheyletiella and Otodectes mite infestations in dogs and cats. ( 15030559 )
2004
47
Efficacy and safety of topical administration of selamectin for treatment of ear mite infestation in rabbits. ( 12906226 )
2003
48
Induction of direct and indirect plant responses by jasmonic acid, low spider mite densities, or a combination of jasmonic acid treatment and spider mite infestation. ( 14969353 )
2003
49
Chigger mite infestation. ( 13130088 )
2003
50
Some observations on the pharmacological properties of ivermectin during treatment of a mite infestation in mice. ( 12906401 )
2003

Variations for Mite Infestation

Expression for Mite Infestation

Search GEO for disease gene expression data for Mite Infestation.

Pathways for Mite Infestation

Pathways related to Mite Infestation according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.61 ATP2A2 CFTR

GO Terms for Mite Infestation

Cellular components related to Mite Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Golgi lumen GO:0005796 8.96 DEFA1 DEFA3
2 azurophil granule lumen GO:0035578 8.62 DEFA1 DEFA3

Biological processes related to Mite Infestation according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 defense response to Gram-positive bacterium GO:0050830 9.49 DEFA1 DEFA3
2 defense response to Gram-negative bacterium GO:0050829 9.48 DEFA1 DEFA3
3 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.46 DEFA1 DEFA3
4 antimicrobial humoral response GO:0019730 9.43 DEFA1 DEFA3
5 killing of cells of other organism GO:0031640 9.4 DEFA1 DEFA3
6 antibacterial humoral response GO:0019731 9.37 DEFA1 DEFA3
7 defense response to virus GO:0051607 9.33 DEFA1 DEFA3 UNC93B1
8 defense response to fungus GO:0050832 9.32 DEFA1 DEFA3
9 innate immune response in mucosa GO:0002227 9.26 DEFA1 DEFA3
10 intracellular estrogen receptor signaling pathway GO:0030520 8.96 DEFA1 DEFA3
11 membrane disruption in other organism GO:0051673 8.62 DEFA1 DEFA3

Sources for Mite Infestation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....