MCID: MTN002
MIFTS: 32

Mite Infestation

Categories: Infectious diseases

Aliases & Classifications for Mite Infestation

MalaCards integrated aliases for Mite Infestation:

Name: Mite Infestation 12 15
Mite Infestations 43 71

Classifications:



External Ids:

Disease Ontology 12 DOID:7894
ICD9CM 34 133
MeSH 43 D008924
SNOMED-CT 67 240885009
ICD10 32 B88.9
UMLS 71 C0026229

Summaries for Mite Infestation

Disease Ontology : 12 A parasitic ectoparasitic infectious disease that involves infestation of mites belonging to the family Sarcoptidae, Trombiculidae and Demodicidae.

MalaCards based summary : Mite Infestation, also known as mite infestations, is related to scabies and lice infestation. An important gene associated with Mite Infestation is CFTR (CF Transmembrane Conductance Regulator), and among its related pathways/superpathways are Defensins and Th2 Differentiation. The drugs Benzyl alcohol and Ethanol have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and colon.

Related Diseases for Mite Infestation

Diseases related to Mite Infestation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 160)
# Related Disease Score Top Affiliating Genes
1 scabies 32.3 TNFRSF8 IL31 FLNA FLG CD4 AADACL3
2 lice infestation 30.3 TXNDC15 MT-CO1 ADSL
3 epidemic typhus 30.1 TXNDC15 CD40LG CD4
4 contact dermatitis 29.5 IL5 IL31 FLG CD4
5 urticaria 29.4 IL5 IL31 CD40LG
6 dermatitis, atopic 29.0 TNFRSF8 IL5 IL31 FLG CD4 ADSL
7 skin disease 28.3 TNFRSF8 IL5 IL31 FLG COL17A1 CD40LG
8 trombiculiasis 11.7
9 demodicidosis 11.6
10 dermatitis 10.5
11 miliaria rubra 10.5 IL31 CFTR
12 parapsoriasis 10.4 TNFRSF8 CD4
13 epidermolysis bullosa pruriginosa 10.4 IL31 FLG
14 follicular mucinosis 10.4 TNFRSF8 CD4
15 cystoisosporiasis 10.4 MT-CO1 CD4
16 reticulum cell sarcoma 10.4 TNFRSF8 CD4
17 pediculus humanus capitis infestation 10.4 TXNDC15 MT-CO1
18 cork-handlers' disease 10.3 CD40LG CD4
19 syphilitic meningitis 10.3 CD40LG CD4
20 early yaws 10.3 CD40LG CD4
21 asymptomatic neurosyphilis 10.3 CD40LG CD4
22 latent syphilis 10.3 CD40LG CD4
23 gastroduodenitis 10.3 CD40LG CD4
24 primary syphilis 10.3 CD40LG CD4
25 necrotizing ulcerative gingivitis 10.3 CD40LG CD4
26 neuroretinitis 10.3 CD40LG CD4
27 tertiary neurosyphilis 10.3 CD40LG CD4
28 bacillary angiomatosis 10.3 CD40LG CD4
29 meningovascular neurosyphilis 10.3 CD40LG CD4
30 keratosis 10.2
31 viral exanthem 10.2 CD40LG CD4
32 tertiary syphilis 10.2 CD40LG CD4
33 acute retinal necrosis syndrome 10.2 CD40LG CD4
34 optic papillitis 10.2 CD40LG CD4
35 opportunistic bacterial infectious disease 10.2 CD40LG CD4
36 neurotic excoriation 10.2 FLNA COL17A1
37 gastrointestinal tuberculosis 10.2 CD40LG CD4
38 alkhurma hemorrhagic fever 10.2 TXNDC15 CD40LG
39 cerebritis 10.2 CD40LG CD4
40 granulomatous hepatitis 10.2 CD40LG CD4
41 retroperitoneal lymphoma 10.2 TNFRSF8 CD40LG
42 exanthema subitum 10.2 CD40LG CD4
43 microsporidiosis 10.2 DEFA1 CD4
44 west nile encephalitis 10.2 CD40LG CD4
45 transient hypogammaglobulinemia 10.2 CD40LG AADACL3
46 autoimmune peripheral neuropathy 10.2 CD40LG CD4
47 congenital syphilis 10.2 CD40LG CD4
48 mononeuritis of upper limb and mononeuritis multiplex 10.2 CD40LG CD4
49 tinea corporis 10.2 IL31 FLNA FLG AADACL3
50 mononeuritis multiplex 10.2 CD40LG CD4

Graphical network of the top 20 diseases related to Mite Infestation:



Diseases related to Mite Infestation

Symptoms & Phenotypes for Mite Infestation

Drugs & Therapeutics for Mite Infestation

Drugs for Mite Infestation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzyl alcohol Approved Phase 2 100-51-6 244
2
Ethanol Approved Phase 2 64-17-5 702
3 Anesthetics Phase 2
4 Anesthetics, Local Phase 2
5 Pharmaceutical Solutions Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized, Double-blind, Multicenter, Vehicle-controlled Study of the Efficacy and Safety of Abametapir Lotion 0.74% Administered for the Treatment of Head Lice Infestation Completed NCT02062060 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
2 A Randomized, Double-Blind, Multicenter, Vehicle-Controlled Study of the Efficacy and Safety of Abametapir Lotion 0.74% Administered for the Treatment of Head Lice Infestation Completed NCT02060903 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
3 A Pediatric Safety and Pharmacokinetic Study of Ha44 Gel Administered Topically for the Treatment of Head Lice Infestation Completed NCT02010333 Phase 2 Ha44 Gel 0.74% w/w
4 A Randomised, Double-Blind, Vehicle-Controlled Study of Ovicidal Efficacy and Safety of Abametapir 0.74% Administered for the Treatment of Head Lice Infestation Completed NCT02097485 Phase 2 Abametapir Lotion 0.74% w/w;Vehicle Lotion
5 A Safety and Pharmacokinetic Study of Ha44 Gel Administered Topically Under Maximal Use Conditions for the Treatment of Head Lice Infestation. Completed NCT01907490 Phase 2 Ha44 Gel

Search NIH Clinical Center for Mite Infestation

Cochrane evidence based reviews: mite infestations

Genetic Tests for Mite Infestation

Anatomical Context for Mite Infestation

MalaCards organs/tissues related to Mite Infestation:

40
Skin, Eye, Colon, T Cells

Publications for Mite Infestation

Articles related to Mite Infestation:

(show top 50) (show all 490)
# Title Authors PMID Year
1
Correction to: Transcriptional and metabolite analysis reveal a shift in direct and indirect defences in response to spider‑mite infestation in cucumber (Cucumis sativus). 61
32350663 2020
2
Transcriptional and metabolite analysis reveal a shift in direct and indirect defences in response to spider-mite infestation in cucumber (Cucumis sativus). 61
32306368 2020
3
A review: application of remote sensing as a promising strategy for insect pests and diseases management. 61
32564316 2020
4
Prevalence of poultry red mite (Dermanyssus gallinae) in Korean layer farms and the presence of avian pathogens in the mite. 61
32435982 2020
5
Otodectes cynotis in urban and peri-urban semi-arid areas: a widespread parasite in the cat population. 61
32508428 2020
6
Prevalence of Ocular Demodex Infestation in Children: An Epidemiological Survey in South China. 61
32443007 2020
7
Parasitic mites alter chicken behaviour and negatively impact animal welfare. 61
32427882 2020
8
Investigation of a gamasid mite infestation in a UK textile mill caused by Dermanyssus gallinae (DeGeer, 1778) (Mesostigmata: Dermanyssidae) special lineage L1. 61
32442496 2020
9
Phytochemical analysis of mite-infested tea leaves of Darjeeling Hills, India. 61
31749250 2020
10
Demodex positive discoid lupus erythematosus: Is it a separate entity or an overlap syndrome? 61
32275797 2020
11
Range expansion of the tracheal mite Acarapis woodi (Acari: Tarsonemidae) among Japanese honey bee, Apis cerana japonica, in Japan. 61
32253641 2020
12
Resistance of some commercial walnut cultivars and genotypes to Aceria tristriata (Nalepa) (Acari: Eriophyidae) and its correlation with some plant features. 61
31489761 2020
13
Case for diagnosis. Erythematous and pruritic papules on forearms. 61
32171542 2020
14
Classic and Non-classic (Surrepticius) Scabies: Diagnostic and Treatment Considerations. 61
32351804 2020
15
Mold mite infestation in toenail dermatophytoma with pustular psoriasis. 61
32077586 2020
16
Storage Mite Infestation of Dry-Stored Food Products and Its Relation to Human Intestinal Acariasis in the City of Minia, Egypt. 61
31742345 2020
17
Kinome Analysis of Honeybee (Apis mellifera L.) Dark-Eyed Pupae Identifies Biomarkers and Mechanisms of Tolerance to Varroa Mite Infestation. 61
32034205 2020
18
Honey Bee Suppresses the Parasitic Mite Vitellogenin by Antimicrobial Peptide. 61
32523577 2020
19
Combined transcriptome and metabolome analysis identifies defence responses in spider mite-infested pepper (Capsicum annuum). 61
31557301 2020
20
Comparative transcriptome provides molecular insight into defense-associated mechanisms against spider mite in resistant and susceptible common bean cultivars. 61
32017794 2020
21
Treatment of Harvest Mite Infestation in Dogs Using a Permethrin 54.5% and Fipronil 6.1% (Effitix®) Topical Spot-On Formulation. 61
31817840 2019
22
Bird mite infestation masquerading as allergic dermatitis. 61
30931526 2019
23
A vaccinology Approach to the Identification and Characterization of Dermanyssus Gallinae Candidate Protective Antigens for the Control of Poultry Red Mite Infestations. 61
31756972 2019
24
Ketalization of 2-heptanone to prolong its activity as mite repellant for the protection of honey bees. 61
31259414 2019
25
Molecular characterization and genetic diversity of Ornithonyssus sylviarum in chickens (Gallus gallus) from Hainan Island, China. 61
31753001 2019
26
Environmental variation mediates the prevalence and co-occurrence of parasites in the common lizard, Zootoca vivipara. 61
31640667 2019
27
Demodex-Mite Infestation in Cilia and its Association With Ocular Surface Parameters in Japanese Volunteers. 61
31517735 2019
28
The Presence of Demodex Mites in Patients with Dermatologic Symptoms of the Face 61
31502805 2019
29
Quill mite infestation of rock ptarmigan Lagopus muta (Aves: Phasianidae) in relation to year and host age, sex, body condition, and density. 61
31278517 2019
30
Feeding by Tropilaelaps mercedesae on pre- and post-capped brood increases damage to Apis mellifera colonies. 61
31506594 2019
31
Population genetics of ectoparasitic mites suggest arms race with honeybee hosts. 61
31388048 2019
32
Demodex Mite Infestation and its Associations with Tear Film and Ocular Surface Parameters in Patients with Ocular Discomfort. 61
30885709 2019
33
Pathology and epidemiology of nasopulmonary acariasis (Halarachne sp.) in southern sea otters (Enhydra lutris nereis). 61
31011527 2019
34
Performance of the Psoroptes ovis antibody enzyme-linked immunosorbent assay in the face of low-level mite infestation. 61
31127028 2019
35
Sarcoptic Mange of Fox Origin in Multiple Farm Animals and Scabies in Humans, Switzerland, 2018. 61
31107228 2019
36
Transcriptomic and proteomic response of Manihot esculenta to Tetranychus urticae infestation at different densities. 61
31168751 2019
37
Efficacy and safety of a combination of selamectin plus sarolaner for the treatment and prevention of flea infestations and the treatment of ear mites in cats presented as veterinary patients in the United States. 61
30579753 2019
38
Increase of scabies infestations, Norway, 2006 to 2018. 61
31186078 2019
39
Honey bee predisposition of resistance to ubiquitous mite infestations. 61
31127129 2019
40
Resin foraging dynamics in Varroa destructor-infested hives: a case of medication of kin? 61
28795524 2019
41
Revealing the structure of the associations between housing system, facilities, management and welfare of commercial laying hens using Additive Bayesian Networks. 61
30771891 2019
42
Physiological Response of Basil Plants to Twospotted Spider Mite (Acari: Tetranychidae) Infestation. 61
30602029 2019
43
Serum and acute phase protein changes in laying hens, infested with poultry red mite. 61
30239853 2019
44
The Dynamics of Deformed Wing Virus Concentration and Host Defensive Gene Expression after Varroa Mite Parasitism in Honey Bees, Apis mellifera. 61
30626033 2019
45
Mite bombs or robber lures? The roles of drifting and robbing in Varroa destructor transmission from collapsing honey bee colonies to their neighbors. 61
31226130 2019
46
Health status of honey bee colonies (Apis mellifera) and disease-related risk factors for colony losses in Austria. 61
31287830 2019
47
Factors restraining the population growth of Varroa destructor in Ethiopian honey bees (Apis mellifera simensis). 61
31557264 2019
48
Subungual and ungual scabies: avoiding severe presentation in high-risk patients. 61
30567157 2018
49
Differential Impact of Herbivores from Three Feeding Guilds on Systemic Secondary Metabolite Induction, Phytohormone Levels and Plant-Mediated Herbivore Interactions. 61
30267359 2018
50
Failure of ivermectin efficacy against Psoroptes ovis infestation in cattle: Integrated pharmacokinetic-pharmacodynamic evaluation of two commercial formulations. 61
30389019 2018

Variations for Mite Infestation

Expression for Mite Infestation

Search GEO for disease gene expression data for Mite Infestation.

Pathways for Mite Infestation

Pathways related to Mite Infestation according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.59 PGLYRP1 DEFA1B DEFA1 CD4
2 10.46 IL5 IL31 CD4

GO Terms for Mite Infestation

Cellular components related to Mite Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.28 PGLYRP1 IL5 IL31 FLNA DEFA1B DEFA1

Biological processes related to Mite Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.8 IL5 DEFA1B DEFA1 CD40LG CD4
2 defense response to Gram-positive bacterium GO:0050830 9.65 PGLYRP1 DEFA1B DEFA1
3 defense response to Gram-negative bacterium GO:0050829 9.63 DEFA1B DEFA1 CD4
4 T cell chemotaxis GO:0010818 9.43 DEFA1B DEFA1
5 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.43 PGLYRP1 DEFA1B DEFA1
6 killing by host of symbiont cells GO:0051873 9.37 DEFA1B DEFA1
7 antimicrobial humoral response GO:0019730 9.33 PGLYRP1 DEFA1B DEFA1
8 membrane disruption in other organism GO:0051673 9.32 DEFA1B DEFA1
9 killing of cells of other organism GO:0031640 9.13 PGLYRP1 DEFA1B DEFA1
10 pore formation in membrane of other organism during symbiotic interaction GO:0044657 8.62 DEFA1B DEFA1

Sources for Mite Infestation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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