MCID: MXD020
MIFTS: 17

Mixed Cell Adenoma

Categories: Cancer diseases

Aliases & Classifications for Mixed Cell Adenoma

MalaCards integrated aliases for Mixed Cell Adenoma:

Name: Mixed Cell Adenoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5385
NCIt 50 C4157
SNOMED-CT 68 89773001
UMLS 73 C0334323

Summaries for Mixed Cell Adenoma

MalaCards based summary : Mixed Cell Adenoma is related to endocrine pancreas disease and tuberous sclerosis 2. An important gene associated with Mixed Cell Adenoma is IRS1 (Insulin Receptor Substrate 1), and among its related pathways/superpathways are Regulation of lipid metabolism Insulin signaling-generic cascades and NFAT and Cardiac Hypertrophy.

Related Diseases for Mixed Cell Adenoma

Diseases related to Mixed Cell Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 endocrine pancreas disease 9.7 IGF1 IRS1
2 tuberous sclerosis 2 9.6 IGF1 IRS1
3 overnutrition 9.6 IGF1 IRS1
4 glucose metabolism disease 9.6 IGF1 IRS1
5 glucose intolerance 9.6 IGF1 IRS1
6 acquired metabolic disease 9.6 IGF1 IRS1
7 insulin-like growth factor i 9.5 IGF1 IRS1
8 polycystic ovary syndrome 9.5 IGF1 IRS1
9 hyperglycemia 9.4 IGF1 IRS1
10 body mass index quantitative trait locus 11 9.3 IGF1 IRS1
11 diabetes mellitus, noninsulin-dependent 9.2 IGF1 IRS1
12 diabetes mellitus 9.0 IGF1 IRS1

Graphical network of the top 20 diseases related to Mixed Cell Adenoma:



Diseases related to Mixed Cell Adenoma

Symptoms & Phenotypes for Mixed Cell Adenoma

Drugs & Therapeutics for Mixed Cell Adenoma

Search Clinical Trials , NIH Clinical Center for Mixed Cell Adenoma

Genetic Tests for Mixed Cell Adenoma

Anatomical Context for Mixed Cell Adenoma

Publications for Mixed Cell Adenoma

Variations for Mixed Cell Adenoma

Expression for Mixed Cell Adenoma

Search GEO for disease gene expression data for Mixed Cell Adenoma.

Pathways for Mixed Cell Adenoma

Pathways related to Mixed Cell Adenoma according to GeneCards Suite gene sharing:

(show all 18)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.35 IGF1 IRS1
2
Show member pathways
12.31 IGF1 IRS1
3
Show member pathways
12.3 IGF1 IRS1
4
Show member pathways
12.23 IGF1 IRS1
5
Show member pathways
12.22 IGF1 IRS1
6
Show member pathways
12.04 IGF1 IRS1
7
Show member pathways
11.97 IGF1 IRS1
8
Show member pathways
11.91 IGF1 IRS1
9
Show member pathways
11.8 IGF1 IRS1
10
Show member pathways
11.63 IGF1 IRS1
11
Show member pathways
11.61 IGF1 IRS1
12
Show member pathways
11.61 IGF1 IRS1
13
Show member pathways
11.57 IGF1 IRS1
14
Show member pathways
11.46 IGF1 IRS1
15 11.38 IGF1 IRS1
16
Show member pathways
11.26 IGF1 IRS1
17 10.52 IGF1 IRS1
18 10.11 IGF1 IRS1

GO Terms for Mixed Cell Adenoma

Biological processes related to Mixed Cell Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.46 IGF1 IRS1
2 glucose homeostasis GO:0042593 9.43 IGF1 IRS1
3 response to insulin GO:0032868 9.4 IGF1 IRS1
4 phosphatidylinositol-mediated signaling GO:0048015 9.37 IGF1 IRS1
5 phosphatidylinositol 3-kinase signaling GO:0014065 9.32 IGF1 IRS1
6 positive regulation of glucose import GO:0046326 9.26 IGF1 IRS1
7 positive regulation of insulin receptor signaling pathway GO:0046628 9.16 IGF1 IRS1
8 positive regulation of glycogen biosynthetic process GO:0045725 8.96 IGF1 IRS1
9 insulin-like growth factor receptor signaling pathway GO:0048009 8.62 IGF1 IRS1

Molecular functions related to Mixed Cell Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 insulin receptor binding GO:0005158 8.96 IGF1 IRS1
2 insulin-like growth factor receptor binding GO:0005159 8.62 IGF1 IRS1

Sources for Mixed Cell Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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