MCID: MXD014
MIFTS: 23

Mixed Ductal-Endocrine Carcinoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Mixed Ductal-Endocrine Carcinoma

MalaCards integrated aliases for Mixed Ductal-Endocrine Carcinoma:

Name: Mixed Ductal-Endocrine Carcinoma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:7716
SNOMED-CT 67 999000
UMLS 70 C1301048

Summaries for Mixed Ductal-Endocrine Carcinoma

MalaCards based summary : Mixed Ductal-Endocrine Carcinoma is related to gastrinoma and papillary carcinoma. An important gene associated with Mixed Ductal-Endocrine Carcinoma is CHGA (Chromogranin A), and among its related pathways/superpathways is Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. Affiliated tissues include pancreas, lung and thyroid.

Related Diseases for Mixed Ductal-Endocrine Carcinoma

Diseases related to Mixed Ductal-Endocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 152)
# Related Disease Score Top Affiliating Genes
1 gastrinoma 30.4 GAST CHGA
2 papillary carcinoma 30.3 SYP CHGA
3 zollinger-ellison syndrome 30.3 GAST CHGA
4 pancreatic gastrinoma 30.0 SYP GAST CHGA
5 autoimmune atrophic gastritis 10.2 GAST CHGA
6 atrophic gastritis 10.2 GAST CHGA
7 gastric gastrinoma 10.2 GAST CHGA
8 multiple endocrine neoplasia 10.2 GAST CHGA
9 non-functioning pancreatic endocrine tumor 10.2 GAST CHGA
10 goblet cell carcinoid 10.2 GAST CHGA
11 duodenal gastrinoma 10.2 GAST CHGA
12 appendix lymphoma 10.2 GAST CHGA
13 endocrine pancreas disease 10.2 GAST CHGA
14 glucagonoma 10.2 GAST CHGA
15 pancreatic cholera 10.2 GAST CHGA
16 cystadenoma 10.2 SYP CHGA
17 primary hepatic neuroendocrine carcinoma 10.2 SYP CHGA
18 esophageal neuroendocrine tumor 10.2 SYP CHGA
19 auditory system benign neoplasm 10.2 SYP CHGA
20 auditory system cancer 10.2 SYP CHGA
21 acinar cell cystadenocarcinoma 10.2 SYP CHGA
22 vulvar eccrine porocarcinoma 10.2 SYP CHGA
23 pancreatic serous cystadenocarcinoma 10.1 SYP CHGA
24 cauda equina neoplasm 10.1 SYP CHGA
25 ampulla of vater benign neoplasm 10.1 SYP CHGA
26 appendix carcinoid tumor 10.1 SYP CHGA
27 carotid body cancer 10.1 SYP CHGA
28 vaginal tubulovillous adenoma 10.1 SYP CHGA
29 laryngeal small cell carcinoma 10.1 SYP CHGA
30 gallbladder small cell carcinoma 10.1 SYP CHGA
31 ureter small cell carcinoma 10.1 SYP CHGA
32 papillary thymic adenocarcinoma 10.1 SYP CHGA
33 middle ear adenoma 10.1 SYP CHGA
34 duodenal benign neoplasm 10.1 SYP CHGA
35 urinary bladder small cell neuroendocrine carcinoma 10.1 SYP CHGA
36 gastric small cell carcinoma 10.1 SYP CHGA
37 breast papillary carcinoma 10.1 SYP CHGA
38 extracranial neuroblastoma 10.1 SYP CHGA
39 sensory organ benign neoplasm 10.1 SYP CHGA
40 cervical neuroblastoma 10.1 SYP CHGA
41 laryngeal neuroendocrine tumor 10.1 SYP CHGA
42 esophageal adenoid cystic carcinoma 10.1 SYP CHGA
43 ovarian large-cell neuroendocrine carcinoma 10.1 SYP CHGA
44 appendix adenocarcinoma 10.1 SYP CHGA
45 gastric hemangioma 10.1 SYP CHGA
46 subependymoma 10.1 SYP CHGA
47 pineocytoma 10.1 SYP CHGA
48 cutaneous ganglioneuroma 10.1 SYP CHGA
49 ganglioneuroma 10.1 SYP CHGA
50 cervix small cell carcinoma 10.1 SYP CHGA

Graphical network of the top 20 diseases related to Mixed Ductal-Endocrine Carcinoma:



Diseases related to Mixed Ductal-Endocrine Carcinoma

Symptoms & Phenotypes for Mixed Ductal-Endocrine Carcinoma

Drugs & Therapeutics for Mixed Ductal-Endocrine Carcinoma

Search Clinical Trials , NIH Clinical Center for Mixed Ductal-Endocrine Carcinoma

Genetic Tests for Mixed Ductal-Endocrine Carcinoma

Anatomical Context for Mixed Ductal-Endocrine Carcinoma

MalaCards organs/tissues related to Mixed Ductal-Endocrine Carcinoma:

40
Pancreas, Lung, Thyroid, Appendix, Breast, Small Intestine, Colon

Publications for Mixed Ductal-Endocrine Carcinoma

Articles related to Mixed Ductal-Endocrine Carcinoma:

(show all 16)
# Title Authors PMID Year
1
Clinicopathological Features of Intraductal Pancreatic Neuroendocrine Tumors. 61
27825416 2016
2
[Mixed ductal endocrine carcinoma of the pancreas]. 61
23010408 2012
3
Mixed ductal-endocrine carcinoma of the pancreas occurring as a double cancer: report of a case. 61
22026308 2011
4
Mixed ductal-endocrine carcinoma of pancreas. 61
22696627 2011
5
A case of mixed ductal-endocrine carcinoma of the pancreas. 61
21424939 2011
6
Mixed ductal-endocrine carcinoma of the pancreas metastatic to the liver. 61
21311316 2011
7
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression. 61
18161862 2008
8
Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors. 61
18453301 2008
9
CD56 (NCAM) expression in pancreatic carcinoma and the surrounding pancreatic tissue. 61
17317933 2006
10
Serous cystic neoplasms of the pancreas: an immunohistochemical analysis revealing alpha-inhibin, neuron-specific enolase, and MUC6 as new markers. 61
15104296 2004
11
Mixed ductal-endocrine carcinomas of the pancreas and ductal adenocarcinomas with scattered endocrine cells: characterization of the endocrine cells. 61
12647216 2003
12
Minute mixed ductal-endocrine carcinoma of the pancreas with predominant intraductal growth. 61
12685552 2002
13
Somatostatin type 2A receptor immunoreactivity in human pancreatic adenocarcinomas. 61
11579680 2001
14
Mixed ductal-endocrine carcinoma of the pancreas: a possible pathogenic mechanism for arrhythmogenic right ventricular cardiomyopathy. 61
10656740 2000
15
Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome: an autopsy case with a 24-year survival period. 61
10628803 1999
16
[The establishment of a human pancreatic mixed ductal-endocrine carcinoma cell line]. 61
11869555 1999

Variations for Mixed Ductal-Endocrine Carcinoma

Expression for Mixed Ductal-Endocrine Carcinoma

Search GEO for disease gene expression data for Mixed Ductal-Endocrine Carcinoma.

Pathways for Mixed Ductal-Endocrine Carcinoma

GO Terms for Mixed Ductal-Endocrine Carcinoma

Cellular components related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 GAST CHGA CGB8 CGB7 CGB3
2 extracellular space GO:0005615 9.02 GAST CHGA CGB8 CGB7 CGB3

Biological processes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor signaling pathway GO:0007186 9.62 GAST CGB8 CGB7 CGB3
2 cell-cell signaling GO:0007267 9.43 CGB8 CGB7 CGB3
3 peptide hormone processing GO:0016486 9.16 CGB8 CGB3
4 hormone-mediated signaling pathway GO:0009755 9.13 CGB8 CGB7 CGB3
5 female gamete generation GO:0007292 8.8 CGB8 CGB7 CGB3

Molecular functions related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.92 GAST CGB8 CGB7 CGB3

Sources for Mixed Ductal-Endocrine Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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