MCID: MXD014
MIFTS: 28

Mixed Ductal-Endocrine Carcinoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Mixed Ductal-Endocrine Carcinoma

MalaCards integrated aliases for Mixed Ductal-Endocrine Carcinoma:

Name: Mixed Ductal-Endocrine Carcinoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7716
NCIt 50 C6879
SNOMED-CT 68 396892009 999000
UMLS 73 C1301048

Summaries for Mixed Ductal-Endocrine Carcinoma

MalaCards based summary : Mixed Ductal-Endocrine Carcinoma is related to zollinger-ellison syndrome and gastrinoma. An important gene associated with Mixed Ductal-Endocrine Carcinoma is CHGA (Chromogranin A), and among its related pathways/superpathways are Adhesion and Cell adhesion_Cell-matrix glycoconjugates. Affiliated tissues include pancreas and liver, and related phenotype is nervous system.

Related Diseases for Mixed Ductal-Endocrine Carcinoma

Diseases related to Mixed Ductal-Endocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 206)
# Related Disease Score Top Affiliating Genes
1 zollinger-ellison syndrome 30.8 CHGA GAST SST
2 gastrinoma 30.8 CHGA GAST SST
3 autoimmune atrophic gastritis 11.0 CHGA GAST
4 gastric gastrinoma 11.0 ENO2 GAST
5 acinar cell cystadenocarcinoma 10.9 CHGA SYP
6 intracranial primitive neuroectodermal tumor 10.9 CHGA ENO2
7 peritoneal serous adenocarcinoma 10.9 CHGA SYP
8 cellular ependymoma 10.9 CHGA SYP
9 primary hepatic neuroendocrine carcinoma 10.9 CHGA SYP
10 malignant sertoli cell tumor 10.9 ENO2 SYP
11 ovarian carcinosarcoma 10.8 ENO2 SYP
12 non-functioning pancreatic endocrine tumor 10.8 CHGA GAST SYP
13 central nervous system primitive neuroectodermal neoplasm 10.8 ENO2 SYP
14 goblet cell carcinoid 10.8 CHGA ENO2 GAST
15 ureter small cell carcinoma 10.8 CHGA ENO2 SYP
16 urinary bladder small cell neuroendocrine carcinoma 10.8 CHGA ENO2 SYP
17 cerebellum cancer 10.8 ENO2 SYP
18 auditory system cancer 10.7 CHGA ENO2 SYP
19 small cell carcinoma of the bladder 10.7 CHGA ENO2 SYP
20 subependymal glioma 10.7 ENO2 SYP
21 pilomatrix carcinoma 10.7 ENO2 MUC1
22 pulmonary large cell neuroendocrine carcinoma 10.7 CHGA ENO2 SYP
23 olfactory nerve neoplasm 10.7 CHGA ENO2 SYP
24 cauda equina neoplasm 10.7 CHGA ENO2 SYP
25 intracranial cysts 10.7 ENO2 MUC1
26 pylorospasm 10.7 GAST SST
27 nodular ganglioneuroblastoma 10.7 CHGA ENO2 SYP
28 pancreatic intraductal papillary-mucinous neoplasm 10.7 MUC1 MUC6
29 pineocytoma 10.7 CHGA ENO2 SYP
30 respiratory system benign neoplasm 10.7 CHGA ENO2 SYP
31 papillary ependymoma 10.7 CHGA ENO2 SYP
32 malignant glandular tumor of peripheral nerve sheath 10.7 SST SYP
33 cerebral neuroblastoma 10.7 ENO2 SYP
34 central neurocytoma 10.7 CHGA ENO2 SYP
35 type c thymoma 10.7 SST SSTR2
36 cranial nerve malignant neoplasm 10.7 CHGA ENO2 SYP
37 tumor of exocrine pancreas 10.7 MUC1 MUC6
38 cerebellar liponeurocytoma 10.7 CHGA ENO2 SYP
39 granulosa cell tumor of the ovary 10.7 CHGA ENO2 SYP
40 clear cell meningioma 10.7 CHGA MUC1
41 ganglioglioma 10.7 CHGA ENO2 SYP
42 extraosseous chondrosarcoma 10.7 ENO2 SYP
43 lung combined type small cell carcinoma 10.7 NCAM1 SYP
44 gastritis 10.7 CHGA GAST MUC6
45 chronic ethmoiditis 10.7 MUC1 MUC6
46 benign ependymoma 10.6 ENO2 SYP
47 multiple mucosal neuroma 10.6 ENO2 NCAM1
48 ureter, cancer of 10.6 CHGA SYP TERT
49 gastrointestinal neuroendocrine benign tumor 10.6 CHGA GAST SST
50 ossifying fibromyxoid tumor 10.6 ENO2 MUC1

Graphical network of the top 20 diseases related to Mixed Ductal-Endocrine Carcinoma:



Diseases related to Mixed Ductal-Endocrine Carcinoma

Symptoms & Phenotypes for Mixed Ductal-Endocrine Carcinoma

MGI Mouse Phenotypes related to Mixed Ductal-Endocrine Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.32 CALB2 CHGB CHL1 ENO2 NCAM1 SMAD4

Drugs & Therapeutics for Mixed Ductal-Endocrine Carcinoma

Search Clinical Trials , NIH Clinical Center for Mixed Ductal-Endocrine Carcinoma

Genetic Tests for Mixed Ductal-Endocrine Carcinoma

Anatomical Context for Mixed Ductal-Endocrine Carcinoma

MalaCards organs/tissues related to Mixed Ductal-Endocrine Carcinoma:

41
Pancreas, Liver

Publications for Mixed Ductal-Endocrine Carcinoma

Articles related to Mixed Ductal-Endocrine Carcinoma:

# Title Authors Year
1
A case of mixed ductal-endocrine carcinoma of the pancreas. ( 21424939 )
2011
2
Mixed ductal-endocrine carcinoma of the pancreas metastatic to the liver. ( 21311316 )
2011
3
Mixed ductal-endocrine carcinoma of the pancreas occurring as a double cancer: report of a case. ( 22026308 )
2011
4
Mixed ductal-endocrine carcinoma of pancreas. ( 22696627 )
2011
5
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression. ( 18161862 )
2008
6
Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors. ( 18453301 )
2008
7
Minute mixed ductal-endocrine carcinoma of the pancreas with predominant intraductal growth. ( 12685552 )
2002
8
Mixed ductal-endocrine carcinoma of the pancreas: a possible pathogenic mechanism for arrhythmogenic right ventricular cardiomyopathy. ( 10656740 )
2000
9
Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome: an autopsy case with a 24-year survival period. ( 10628803 )
1999

Variations for Mixed Ductal-Endocrine Carcinoma

Expression for Mixed Ductal-Endocrine Carcinoma

Search GEO for disease gene expression data for Mixed Ductal-Endocrine Carcinoma.

Pathways for Mixed Ductal-Endocrine Carcinoma

Pathways related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.42 CEACAM5 MUC1 NCAM1
2 10.39 CEACAM5 MUC1 NCAM1
3 9.8 GAST MUC6

GO Terms for Mixed Ductal-Endocrine Carcinoma

Cellular components related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.4 CEACAM5 CGB3 CGB7 CGB8 CHGA CHGB

Biological processes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.56 CGB3 CGB7 CGB8 SST
2 regulation of signaling receptor activity GO:0010469 9.43 CGB3 CGB7 CGB8 CHGB GAST SST
3 ovulation GO:0030728 9.16 CGB3 CGB7
4 female gamete generation GO:0007292 8.8 CGB3 CGB7 CGB8

Molecular functions related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.02 CGB3 CGB7 CHGB GAST SST

Sources for Mixed Ductal-Endocrine Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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