MCID: MXD014
MIFTS: 30

Mixed Ductal-Endocrine Carcinoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Mixed Ductal-Endocrine Carcinoma

MalaCards integrated aliases for Mixed Ductal-Endocrine Carcinoma:

Name: Mixed Ductal-Endocrine Carcinoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:7716
NCIt 51 C6879
SNOMED-CT 69 999000
UMLS 74 C1301048

Summaries for Mixed Ductal-Endocrine Carcinoma

MalaCards based summary : Mixed Ductal-Endocrine Carcinoma is related to gastrinoma and zollinger-ellison syndrome. An important gene associated with Mixed Ductal-Endocrine Carcinoma is CHGA (Chromogranin A), and among its related pathways/superpathways are Adhesion and Cell adhesion_Cell-matrix glycoconjugates. Affiliated tissues include lung, pancreas and liver, and related phenotype is nervous system.

Related Diseases for Mixed Ductal-Endocrine Carcinoma

Diseases related to Mixed Ductal-Endocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 224)
# Related Disease Score Top Affiliating Genes
1 gastrinoma 30.6 CHGA GAST SST
2 zollinger-ellison syndrome 30.5 CHGA GAST SST
3 peritoneal serous adenocarcinoma 10.5 CHGA SYP
4 cellular ependymoma 10.5 CHGA SYP
5 olfactory groove meningioma 10.5 CHGA SYP
6 acinar cell cystadenocarcinoma 10.5 CHGA SYP
7 primary hepatic neuroendocrine carcinoma 10.5 CHGA SYP
8 acute thyroiditis 10.5 CHGA ENO2
9 lung oat cell carcinoma 10.5 CHGA ENO2
10 sensory organ benign neoplasm 10.5 ENO2 SYP
11 central nervous system primitive neuroectodermal neoplasm 10.5 ENO2 SYP
12 melanotic neuroectodermal tumor 10.5 ENO2 SYP
13 cerebral ventricle cancer 10.5 ENO2 SYP
14 cerebral neuroblastoma 10.5 ENO2 SYP
15 cerebellum cancer 10.5 ENO2 SYP
16 extraosseous chondrosarcoma 10.5 ENO2 SYP
17 pineal gland cancer 10.5 ENO2 SYP
18 subependymal glioma 10.5 ENO2 SYP
19 benign ependymoma 10.5 ENO2 SYP
20 malignant teratoma 10.5 ENO2 SYP
21 astroblastoma 10.5 ENO2 SYP
22 pylorospasm 10.5 GAST SST
23 panophthalmitis 10.5 SYP TERT
24 pituitary carcinoma 10.5 CHGA SST
25 postcholecystectomy syndrome 10.4 GAST SST
26 autoimmune atrophic gastritis 10.4 CHGA GAST
27 clear cell meningioma 10.4 CHGA MUC1
28 sarcomatoid renal cell carcinoma 10.4 CGB3 MUC1
29 ureter small cell carcinoma 10.4 CHGA SYP
30 malignant glandular tumor of peripheral nerve sheath 10.4 SST SYP
31 retroperitoneal neuroblastoma 10.4 ENO2 SST
32 gastric gastrinoma 10.4 ENO2 GAST
33 mongolian spot 10.4 ENO2 SST
34 duodenal somatostatinoma 10.4 ENO2 SST
35 solid adenocarcinoma with mucin production 10.4 MUC1 MUC6
36 tumor of exocrine pancreas 10.4 MUC1 MUC6
37 adenomyoma 10.4 MUC1 MUC6
38 ovarian small cell carcinoma 10.4 MUC1 SYP
39 ossifying fibromyxoid tumor 10.4 ENO2 MUC1
40 pancreatic intraductal papillary-mucinous neoplasm 10.4 MUC1 MUC6
41 type c thymoma 10.4 SST SSTR2
42 chronic ethmoiditis 10.4 MUC1 MUC6
43 hormone producing pituitary cancer 10.4 SST SSTR2
44 carotid body cancer 10.4 ENO2 SYP
45 supratentorial primitive neuroectodermal tumor 10.4 NCAM1 SYP
46 lung combined type small cell carcinoma 10.4 NCAM1 SYP
47 mediastinal cancer 10.4 NCAM1 SYP
48 hypoganglionosis 10.4 NCAM1 SYP
49 middle cerebral artery infarction 10.4 ENO2 NCAM1
50 choriocarcinoma of ovary 10.4 ENO2 NCAM1

Graphical network of the top 20 diseases related to Mixed Ductal-Endocrine Carcinoma:



Diseases related to Mixed Ductal-Endocrine Carcinoma

Symptoms & Phenotypes for Mixed Ductal-Endocrine Carcinoma

MGI Mouse Phenotypes related to Mixed Ductal-Endocrine Carcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.36 CALB2 CHGA CHGB CHL1 ENO2 NCAM1

Drugs & Therapeutics for Mixed Ductal-Endocrine Carcinoma

Search Clinical Trials , NIH Clinical Center for Mixed Ductal-Endocrine Carcinoma

Genetic Tests for Mixed Ductal-Endocrine Carcinoma

Anatomical Context for Mixed Ductal-Endocrine Carcinoma

MalaCards organs/tissues related to Mixed Ductal-Endocrine Carcinoma:

42
Lung, Pancreas, Liver, Pituitary, Thyroid, Testis, Colon

Publications for Mixed Ductal-Endocrine Carcinoma

Articles related to Mixed Ductal-Endocrine Carcinoma:

# Title Authors Year
1
Mixed ductal-endocrine carcinoma of the pancreas metastatic to the liver. ( 21311316 )
2011
2
A case of mixed ductal-endocrine carcinoma of the pancreas. ( 21424939 )
2011
3
Mixed ductal-endocrine carcinoma of the pancreas occurring as a double cancer: report of a case. ( 22026308 )
2011
4
Mixed ductal-endocrine carcinoma of pancreas. ( 22696627 )
2011
5
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression. ( 18161862 )
2008
6
Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors. ( 18453301 )
2008
7
Minute mixed ductal-endocrine carcinoma of the pancreas with predominant intraductal growth. ( 12685552 )
2002
8
Mixed ductal-endocrine carcinoma of the pancreas: a possible pathogenic mechanism for arrhythmogenic right ventricular cardiomyopathy. ( 10656740 )
2000
9
Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome: an autopsy case with a 24-year survival period. ( 10628803 )
1999

Variations for Mixed Ductal-Endocrine Carcinoma

Expression for Mixed Ductal-Endocrine Carcinoma

Search GEO for disease gene expression data for Mixed Ductal-Endocrine Carcinoma.

Pathways for Mixed Ductal-Endocrine Carcinoma

Pathways related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.42 CEACAM5 MUC1 NCAM1
2 10.39 CEACAM5 MUC1 NCAM1
3 9.8 GAST MUC6

GO Terms for Mixed Ductal-Endocrine Carcinoma

Cellular components related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 CGB7 CGB8 CHGA CHGB ENO2 GAST
2 extracellular region GO:0005576 9.4 NCAM1 CEACAM5 CGB3 CGB7 CGB8 CHGA

Biological processes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.56 CGB3 CGB7 CGB8 SST
2 regulation of signaling receptor activity GO:0010469 9.43 CHGB GAST SST CGB3 CGB7 CGB8
3 hormone-mediated signaling pathway GO:0009755 9.33 CGB3 CGB7 CGB8
4 peptide hormone processing GO:0016486 9.32 CGB3 CGB8
5 female gamete generation GO:0007292 8.8 CGB8 CGB7 CGB3

Molecular functions related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.02 CGB3 CGB7 CHGB GAST SST

Sources for Mixed Ductal-Endocrine Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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