MCID: MXD014
MIFTS: 30

Mixed Ductal-Endocrine Carcinoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Mixed Ductal-Endocrine Carcinoma

MalaCards integrated aliases for Mixed Ductal-Endocrine Carcinoma:

Name: Mixed Ductal-Endocrine Carcinoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7716
NCIt 50 C6879
SNOMED-CT 68 999000
UMLS 73 C1301048

Summaries for Mixed Ductal-Endocrine Carcinoma

MalaCards based summary : Mixed Ductal-Endocrine Carcinoma is related to gastrinoma and zollinger-ellison syndrome. An important gene associated with Mixed Ductal-Endocrine Carcinoma is CHGA (Chromogranin A), and among its related pathways/superpathways are Adhesion and Cell adhesion_Cell-matrix glycoconjugates. Affiliated tissues include pancreas, lung and ovary, and related phenotype is nervous system.

Related Diseases for Mixed Ductal-Endocrine Carcinoma

Diseases related to Mixed Ductal-Endocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 225)
# Related Disease Score Top Affiliating Genes
1 gastrinoma 30.4 CHGA GAST SST
2 zollinger-ellison syndrome 30.4 CHGA GAST SST
3 peritoneal serous adenocarcinoma 10.3 CHGA SYP
4 cellular ependymoma 10.3 CHGA SYP
5 olfactory groove meningioma 10.3 CHGA SYP
6 acinar cell cystadenocarcinoma 10.3 CHGA SYP
7 primary hepatic neuroendocrine carcinoma 10.3 CHGA SYP
8 acute thyroiditis 10.3 CHGA ENO2
9 lung oat cell carcinoma 10.3 CHGA ENO2
10 sensory organ benign neoplasm 10.3 ENO2 SYP
11 central nervous system primitive neuroectodermal neoplasm 10.3 ENO2 SYP
12 cerebral ventricle cancer 10.3 ENO2 SYP
13 cerebral neuroblastoma 10.3 ENO2 SYP
14 cerebellum cancer 10.3 ENO2 SYP
15 extraosseous chondrosarcoma 10.3 ENO2 SYP
16 pineal gland cancer 10.3 ENO2 SYP
17 subependymal glioma 10.3 ENO2 SYP
18 benign ependymoma 10.3 ENO2 SYP
19 malignant teratoma 10.3 ENO2 SYP
20 astroblastoma 10.3 ENO2 SYP
21 pylorospasm 10.3 GAST SST
22 pituitary carcinoma 10.3 CHGA SST
23 panophthalmitis 10.3 SYP TERT
24 postcholecystectomy syndrome 10.3 GAST SST
25 autoimmune atrophic gastritis 10.3 CHGA GAST
26 malignant glandular tumor of peripheral nerve sheath 10.3 SST SYP
27 type c thymoma 10.3 SST SSTR2
28 ureter small cell carcinoma 10.3 CHGA SYP
29 hormone producing pituitary cancer 10.3 SST SSTR2
30 retroperitoneal neuroblastoma 10.3 ENO2 SST
31 gastric gastrinoma 10.3 ENO2 GAST
32 supratentorial primitive neuroectodermal tumor 10.3 NCAM1 SYP
33 clear cell meningioma 10.3 CHGA MUC1
34 lung combined type small cell carcinoma 10.3 NCAM1 SYP
35 mongolian spot 10.3 ENO2 SST
36 mediastinal cancer 10.3 NCAM1 SYP
37 hypoganglionosis 10.3 NCAM1 SYP
38 duodenal somatostatinoma 10.3 ENO2 SST
39 sarcomatoid renal cell carcinoma 10.3 CGB3 MUC1
40 middle cerebral artery infarction 10.3 ENO2 NCAM1
41 choriocarcinoma of ovary 10.2 ENO2 NCAM1
42 ovarian small cell carcinoma 10.2 MUC1 SYP
43 solid adenocarcinoma with mucin production 10.2 MUC1 MUC6
44 carotid body cancer 10.2 ENO2 SYP
45 tumor of exocrine pancreas 10.2 MUC1 MUC6
46 adenomyoma 10.2 MUC1 MUC6
47 ossifying fibromyxoid tumor 10.2 ENO2 MUC1
48 pancreatic intraductal papillary-mucinous neoplasm 10.2 MUC1 MUC6
49 chronic ethmoiditis 10.2 MUC1 MUC6
50 non-functioning pancreatic endocrine tumor 10.2 CHGA GAST SYP

Graphical network of the top 20 diseases related to Mixed Ductal-Endocrine Carcinoma:



Diseases related to Mixed Ductal-Endocrine Carcinoma

Symptoms & Phenotypes for Mixed Ductal-Endocrine Carcinoma

MGI Mouse Phenotypes related to Mixed Ductal-Endocrine Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.36 CALB2 CHGA CHGB CHL1 ENO2 NCAM1

Drugs & Therapeutics for Mixed Ductal-Endocrine Carcinoma

Search Clinical Trials , NIH Clinical Center for Mixed Ductal-Endocrine Carcinoma

Genetic Tests for Mixed Ductal-Endocrine Carcinoma

Anatomical Context for Mixed Ductal-Endocrine Carcinoma

MalaCards organs/tissues related to Mixed Ductal-Endocrine Carcinoma:

41
Pancreas, Lung, Ovary, Pituitary, Thyroid, Testis, Pineal

Publications for Mixed Ductal-Endocrine Carcinoma

Articles related to Mixed Ductal-Endocrine Carcinoma:

# Title Authors Year
1
A case of mixed ductal-endocrine carcinoma of the pancreas. ( 21424939 )
2011
2
Mixed ductal-endocrine carcinoma of the pancreas metastatic to the liver. ( 21311316 )
2011
3
Mixed ductal-endocrine carcinoma of the pancreas occurring as a double cancer: report of a case. ( 22026308 )
2011
4
Mixed ductal-endocrine carcinoma of pancreas. ( 22696627 )
2011
5
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression. ( 18161862 )
2008
6
Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors. ( 18453301 )
2008
7
Minute mixed ductal-endocrine carcinoma of the pancreas with predominant intraductal growth. ( 12685552 )
2002
8
Mixed ductal-endocrine carcinoma of the pancreas: a possible pathogenic mechanism for arrhythmogenic right ventricular cardiomyopathy. ( 10656740 )
2000
9
Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome: an autopsy case with a 24-year survival period. ( 10628803 )
1999

Variations for Mixed Ductal-Endocrine Carcinoma

Expression for Mixed Ductal-Endocrine Carcinoma

Search GEO for disease gene expression data for Mixed Ductal-Endocrine Carcinoma.

Pathways for Mixed Ductal-Endocrine Carcinoma

Pathways related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.42 CEACAM5 MUC1 NCAM1
2 10.39 CEACAM5 MUC1 NCAM1
3 9.8 GAST MUC6

GO Terms for Mixed Ductal-Endocrine Carcinoma

Cellular components related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 CGB3 CGB7 CGB8 CHGA CHGB ENO2
2 extracellular region GO:0005576 9.4 CEACAM5 CGB3 CGB7 CGB8 CHGA CHGB

Biological processes related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.56 CGB3 CGB7 CGB8 SST
2 regulation of signaling receptor activity GO:0010469 9.43 CGB3 CGB7 CGB8 CHGB GAST SST
3 hormone-mediated signaling pathway GO:0009755 9.33 CGB3 CGB7 CGB8
4 peptide hormone processing GO:0016486 9.32 CGB3 CGB8
5 female gamete generation GO:0007292 8.8 CGB3 CGB7 CGB8

Molecular functions related to Mixed Ductal-Endocrine Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.02 CGB3 CGB7 CHGB GAST SST

Sources for Mixed Ductal-Endocrine Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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