MCID: MXD006
MIFTS: 26

Mixed Liposarcoma

Categories: Cancer diseases

Aliases & Classifications for Mixed Liposarcoma

MalaCards integrated aliases for Mixed Liposarcoma:

Name: Mixed Liposarcoma 12 15 73
Mixed-Type Liposarcoma 12 15
Myxoid/round Cell Liposarcoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5703 DOID:5709
NCIt 50 C4253 C27781
SNOMED-CT 68 11073003

Summaries for Mixed Liposarcoma

MalaCards based summary : Mixed Liposarcoma, also known as mixed-type liposarcoma, is related to liposarcoma and ring chromosome 7. An important gene associated with Mixed Liposarcoma is MDM2 (MDM2 Proto-Oncogene), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Endometrial cancer. Related phenotype is hematopoietic system.

Related Diseases for Mixed Liposarcoma

Diseases related to Mixed Liposarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
# Related Disease Score Top Affiliating Genes
1 liposarcoma 27.9 CD34 CDK4 DDIT3 FUS MB MDM2
2 ring chromosome 7 10.8 CDK4 MDM2
3 undifferentiated embryonal sarcoma of the liver 10.8 CDK4 MDM2
4 infiltrating angiolipoma 10.8 CDK4 MDM2
5 spindle cell lipoma 10.8 CDK4 MDM2
6 bone osteosarcoma 10.7 CDK4 MDM2
7 lipoblastoma 10.7 CDK4 MDM2
8 mesenchymoma 10.7 MB MDM2
9 malignant fibrous histiocytoma of bone 10.7 CDK4 MDM2
10 periosteal chondrosarcoma 10.7 CDK4 MDM2
11 well-differentiated liposarcoma 10.7 CDK4 MDM2
12 dedifferentiated liposarcoma 10.7 CDK4 MDM2
13 small cell sarcoma 10.6 CDK4 MDM2
14 juxtacortical osteosarcoma 10.6 CDK4 MDM2
15 embryonal sarcoma 10.6 CDK4 MDM2
16 adult fibrosarcoma 10.6 MB PDGFB
17 myxofibrosarcoma 10.5 CREB3L2 FUS
18 lipomatosis, multiple 10.5 CDK4 FUS MDM2
19 peripheral osteosarcoma 10.5 CDK4 MDM2
20 hemangiopericytoma, malignant 10.5 HBA1 MDM2
21 heart sarcoma 10.4 CREB3L2 MDM2
22 ovary sarcoma 10.4 CD34 HBA1
23 ovarian angiosarcoma 10.4 CD34 HBA1
24 intravascular fasciitis 10.4 CD34 HBA1
25 pediatric angiosarcoma 10.4 CD34 HBA1
26 malignant mesenchymoma 10.4 CDK4 MB MDM2
27 thyroid angiosarcoma 10.4 CD34 HBA1
28 neurogenic arthropathy 10.4 CD34 HBA1
29 rhabdomyosarcoma 2 10.4 CDK4 MB MDM2
30 spleen angiosarcoma 10.4 CD34 HBA1
31 leiomyosarcoma 10.4 CDK4 MB MDM2
32 bone epithelioid hemangioma 10.4 CD34 HBA1
33 thyroid sarcoma 10.4 CD34 HBA1
34 hobnail hemangioma 10.4 CD34 HBA1
35 pericardium cancer 10.4 HBA1 MB
36 malignant fibroxanthoma 10.4 CDK4 MDM2
37 nominal aphasia 10.3 FUS PDGFB
38 breast angiosarcoma 10.3 CD34 HBA1
39 conventional angiosarcoma 10.3 CD34 HBA1
40 venous hemangioma 10.3 CD34 HBA1
41 senile angioma 10.3 CD34 HBA1
42 interstitial emphysema 10.3 CD34 HBA1
43 chorioangioma 10.3 CD34 HBA1
44 mesenchymal cell neoplasm 10.2 CD34 HBA1
45 lymphangiosarcoma 10.2 CD34 HBA1
46 pericardial mesothelioma 10.2 HBA1 MB
47 spindle cell synovial sarcoma 10.2 CD34 MB
48 deep angioma 10.2 CD34 CREB3L2
49 periosteal osteogenic sarcoma 10.2 CD34 CDK4 MDM2
50 fibrosarcoma of bone 10.2 CDK4 CREB3L2 MDM2

Graphical network of the top 20 diseases related to Mixed Liposarcoma:



Diseases related to Mixed Liposarcoma

Symptoms & Phenotypes for Mixed Liposarcoma

MGI Mouse Phenotypes related to Mixed Liposarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.17 CD34 CD68 CDK4 DDIT3 MB MDM2

Drugs & Therapeutics for Mixed Liposarcoma

Search Clinical Trials , NIH Clinical Center for Mixed Liposarcoma

Genetic Tests for Mixed Liposarcoma

Anatomical Context for Mixed Liposarcoma

Publications for Mixed Liposarcoma

Articles related to Mixed Liposarcoma:

# Title Authors Year
1
Spermatic cord mixed liposarcoma. Case report and review of the literature. ( 18273513 )
2008
2
Radiologically and histologically mixed liposarcoma: a report of two biphasic cases. ( 14594943 )
2003

Variations for Mixed Liposarcoma

Expression for Mixed Liposarcoma

Search GEO for disease gene expression data for Mixed Liposarcoma.

Pathways for Mixed Liposarcoma

GO Terms for Mixed Liposarcoma

Biological processes related to Mixed Liposarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heart development GO:0007507 9.63 MB MDM2 PDGFB
2 negative regulation of gene expression GO:0010629 9.5 CD34 MDM2 PDGFB
3 positive regulation of cell cycle GO:0045787 9.43 CDK4 MDM2
4 cellular response to organic substance GO:0071310 9.4 CD68 MDM2
5 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.37 MDM2 PDGFB
6 negative regulation of cell cycle arrest GO:0071157 9.26 CDK4 MDM2
7 positive regulation of vascular associated smooth muscle cell migration GO:1904754 9.16 MDM2 PDGFB
8 oxygen transport GO:0015671 8.96 HBA1 MB
9 paracrine signaling GO:0038001 8.62 CD34 PDGFB

Molecular functions related to Mixed Liposarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxygen carrier activity GO:0005344 8.62 HBA1 MB

Sources for Mixed Liposarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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