MCID: MXD006
MIFTS: 35

Mixed Liposarcoma

Categories: Cancer diseases

Aliases & Classifications for Mixed Liposarcoma

MalaCards integrated aliases for Mixed Liposarcoma:

Name: Mixed Liposarcoma 12 15 73
Mixed-Type Liposarcoma 12 15
Myxoid/round Cell Liposarcoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5703 DOID:5709
NCIt 50 C4253 C27781
SNOMED-CT 68 11073003

Summaries for Mixed Liposarcoma

MalaCards based summary : Mixed Liposarcoma, also known as mixed-type liposarcoma, is related to liposarcoma and ring chromosome 7. An important gene associated with Mixed Liposarcoma is MDM2 (MDM2 Proto-Oncogene), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Endometrial cancer. Affiliated tissues include t cells, skin and brain, and related phenotype is hematopoietic system.

Related Diseases for Mixed Liposarcoma

Diseases related to Mixed Liposarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 110)
# Related Disease Score Top Affiliating Genes
1 liposarcoma 29.4 CD34 CDK4 DDIT3 FUS MB MDM2
2 ring chromosome 7 10.2 CDK4 MDM2
3 mesenchymoma 10.2 MB MDM2
4 undifferentiated embryonal sarcoma of the liver 10.2 CDK4 MDM2
5 embryonal sarcoma 10.2 CDK4 MDM2
6 infiltrating angiolipoma 10.2 CDK4 MDM2
7 spindle cell lipoma 10.2 CDK4 MDM2
8 lipoblastoma 10.2 CDK4 MDM2
9 malignant fibrous histiocytoma of bone 10.2 CDK4 MDM2
10 bone osteosarcoma 10.2 CDK4 MDM2
11 periosteal chondrosarcoma 10.2 CDK4 MDM2
12 well-differentiated liposarcoma 10.2 CDK4 MDM2
13 small cell sarcoma 10.2 CDK4 MDM2
14 juxtacortical osteosarcoma 10.2 CDK4 MDM2
15 focal hand dystonia 10.2 FUS PDGFB
16 peripheral osteosarcoma 10.2 CDK4 MDM2
17 cellular myxoid liposarcoma 10.1 CDK4 FUS MDM2
18 myxofibrosarcoma 10.1 CREB3L2 FUS
19 atypical lipomatous tumor 10.1 CDK4 FUS MDM2
20 lipomatosis, multiple 10.1 CDK4 FUS MDM2
21 malignant fibroxanthoma 10.1 CDK4 MDM2
22 heart sarcoma 10.1 CREB3L2 MDM2
23 histiocytoma 10.1 FUS MB MDM2
24 skin epithelioid hemangioma 10.1 CD34 HBA1
25 hemangiopericytoma, malignant 10.1 HBA1 MDM2
26 dedifferentiated liposarcoma 10.1 CDK4 MB MDM2
27 ovary sarcoma 10.1 CD34 HBA1
28 ovarian angiosarcoma 10.1 CD34 HBA1
29 intravascular fasciitis 10.1 CD34 HBA1
30 malignant mesenchymoma 10.1 CDK4 MB MDM2
31 pediatric angiosarcoma 10.1 CD34 HBA1
32 thyroid angiosarcoma 10.1 CD34 HBA1
33 spleen angiosarcoma 10.1 CD34 HBA1
34 rhabdomyosarcoma 10.1 CDK4 MB MDM2
35 rhabdomyosarcoma 2 10.1 CDK4 MB MDM2
36 pericardium cancer 10.1 HBA1 MB
37 leiomyosarcoma 10.1 CDK4 MB MDM2
38 bone epithelioid hemangioma 10.1 CD34 HBA1
39 thyroid sarcoma 10.1 CD34 HBA1
40 hobnail hemangioma 10.1 CD34 HBA1
41 hordeolum 10.1 CD34 HBA1
42 conventional angiosarcoma 10.1 CD34 HBA1
43 uterine sarcoma 10.1 MB MDM2
44 venous hemangioma 10.1 CD34 HBA1
45 breast angiosarcoma 10.1 CD34 HBA1
46 senile angioma 10.1 CD34 HBA1
47 cardiovascular organ benign neoplasm 10.1 CD34 MB
48 interstitial emphysema 10.1 CD34 HBA1
49 chorioangioma 10.1 CD34 HBA1
50 alveoli adenoma 10.1 CD34 HBA1

Graphical network of the top 20 diseases related to Mixed Liposarcoma:



Diseases related to Mixed Liposarcoma

Symptoms & Phenotypes for Mixed Liposarcoma

MGI Mouse Phenotypes related to Mixed Liposarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.17 CD34 CD68 CDK4 DDIT3 MB MDM2

Drugs & Therapeutics for Mixed Liposarcoma

Search Clinical Trials , NIH Clinical Center for Mixed Liposarcoma

Genetic Tests for Mixed Liposarcoma

Anatomical Context for Mixed Liposarcoma

MalaCards organs/tissues related to Mixed Liposarcoma:

41
T Cells, Skin, Brain, Liver, Bone, Spleen, Thyroid

Publications for Mixed Liposarcoma

Articles related to Mixed Liposarcoma:

# Title Authors Year
1
Spermatic cord mixed liposarcoma. Case report and review of the literature. ( 18273513 )
2008
2
Radiologically and histologically mixed liposarcoma: a report of two biphasic cases. ( 14594943 )
2003

Variations for Mixed Liposarcoma

Expression for Mixed Liposarcoma

Search GEO for disease gene expression data for Mixed Liposarcoma.

Pathways for Mixed Liposarcoma

GO Terms for Mixed Liposarcoma

Biological processes related to Mixed Liposarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.58 CD34 MDM2 PDGFB
2 heart development GO:0007507 9.54 MB MDM2 PDGFB
3 positive regulation of gene expression GO:0010628 9.46 CD34 CREB3L2 MDM2 PDGFB
4 positive regulation of vascular associated smooth muscle cell migration GO:1904754 9.32 MDM2 PDGFB
5 negative regulation of cell cycle arrest GO:0071157 9.26 CDK4 MDM2
6 oxygen transport GO:0015671 8.96 HBA1 MB
7 paracrine signaling GO:0038001 8.62 CD34 PDGFB

Molecular functions related to Mixed Liposarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxygen binding GO:0019825 8.96 HBA1 MB
2 oxygen carrier activity GO:0005344 8.62 HBA1 MB

Sources for Mixed Liposarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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