MCID: MXD019
MIFTS: 23

Mixed Malaria

Categories: Infectious diseases

Aliases & Classifications for Mixed Malaria

MalaCards integrated aliases for Mixed Malaria:

Name: Mixed Malaria 12 15 73
Malaria Fever by More Than One Parasite 12
Malaria by More Than One Parasite 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14325
ICD9CM 35 084.5
SNOMED-CT 68 21070001
UMLS 73 C0153121

Summaries for Mixed Malaria

Disease Ontology : 12 A malaria that involves infection with more than one species of Plasmodium at the same time.

MalaCards based summary : Mixed Malaria, also known as malaria fever by more than one parasite, is related to malaria and multiple sclerosis. An important gene associated with Mixed Malaria is RCAN1 (Regulator Of Calcineurin 1), and among its related pathways/superpathways is Role of Calcineurin-dependent NFAT signaling in lymphocytes. The drugs chloroquine and Miconazole have been mentioned in the context of this disorder.

Related Diseases for Mixed Malaria

Diseases related to Mixed Malaria via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 malaria 28.4 ACKR1 F3 MT-CYB
2 multiple sclerosis 9.6
3 cholecystitis 9.6
4 acalculous cholecystitis 9.6
5 pancreatitis 9.6
6 acute disseminated encephalomyelitis 9.6
7 plasmodium ovale malaria 9.2 MT-CYB NPCDR1
8 coccidiosis 9.1 MT-CYB NPCDR1
9 parasitic protozoa infectious disease 8.7 ACKR1 MT-CYB NPCDR1

Graphical network of the top 20 diseases related to Mixed Malaria:



Diseases related to Mixed Malaria

Symptoms & Phenotypes for Mixed Malaria

Drugs & Therapeutics for Mixed Malaria

Drugs for Mixed Malaria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
chloroquine Approved, Investigational, Vet_approved Phase 4 54-05-7 2719
2
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
3
Primaquine Approved Phase 4 90-34-6 4908
4
Lumefantrine Approved Phase 4 82186-77-4 6437380
5
Artemether Approved Phase 4 71963-77-4 119380 68911
6 Chloroquine diphosphate Phase 4 50-63-5
7 Analgesics Phase 4
8 Analgesics, Non-Narcotic Phase 4
9 Anthelmintics Phase 4
10 Peripheral Nervous System Agents Phase 4
11 Anti-Infective Agents Phase 4
12 Antifungal Agents Phase 4
13 Antiparasitic Agents Phase 4
14 Antiprotozoal Agents Phase 4
15 Anti-Inflammatory Agents Phase 4
16 Anti-Inflammatory Agents, Non-Steroidal Phase 4
17 Antimalarials Phase 4
18 Artemether-lumefantrine combination Phase 4
19 Artemisinine Phase 4
20 Artemisinins Phase 4
21 Antirheumatic Agents Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh Completed NCT02389374 Phase 4 chloroquine;Artemether-lumefantrine combination;Primaquine;Primaquine
2 Optimizing Sysmex Technology as an Innovative Tool to Differentiate Between Malaria (PALUdism) and BACterial Infections in a Malaria Endemic Region Completed NCT02669823

Search NIH Clinical Center for Mixed Malaria

Genetic Tests for Mixed Malaria

Anatomical Context for Mixed Malaria

Publications for Mixed Malaria

Articles related to Mixed Malaria:

(show all 16)
# Title Authors Year
1
Successful management of necrotizing pancreatitis in mixed malaria and review of literature. ( 29930900 )
2018
2
Early treatment failure in concurrent dengue and mixed malaria species infection with suspected resistance to artemisinin combination therapy from a tertiary care center in Delhi: a case report. ( 28860870 )
2017
3
Molecular investigation of mixed malaria infections in southwest Saudi Arabia. ( 25719595 )
2015
4
Molecular evidence of Plasmodium vivax mono and mixed malaria parasite infections in Duffy-negative native Cameroonians. ( 25084090 )
2014
5
Acute disseminated encephalomyelitis after mixed malaria infection (Plasmodium falciparum and Plasmodium vivax) with MRI closely simulating multiple sclerosis. ( 21881471 )
2011
6
A review of mixed malaria species infections in anopheline mosquitoes. ( 21880138 )
2011
7
Infectious disease case: mixed malaria infection with Plasmodium falciparum and Plasmodium vivax in a deployed service member in Afghanistan. ( 22128640 )
2011
8
Acute acalculous cholecystitis complicating an imported case of mixed malaria caused by Plasmodium falciparum and Plasmodium vivax. ( 19932042 )
2010
9
Sub-microscopic malaria cases and mixed malaria infection in a remote area of high malaria endemicity in Rattanakiri province, Cambodia: implication for malaria elimination. ( 20409349 )
2010
10
A mixed malaria infection: is Plasmodium vivax good for you? ( 19740502 )
2010
11
Symmetric peripheral gangrene with mixed malaria. ( 17595506 )
2007
12
Mixed malaria infection. ( 10071374 )
1999
13
Transmission of mixed malaria species and strains by mosquitoes, as detected by PCR, in a study area in Guinea-Bissau. ( 9419850 )
1997
14
Comparative efficacy of combination fansidar-sulphate quinine and fansidar-chloroquine in mixed malaria infections of P. falciparum-P. vivax in children. ( 1956694 )
1991
15
Malarial infections in Aotus trivirgatus with special reference to renal pathology. II. P. falciparum and mixed malaria infections. ( 813757 )
1975
16
Leukemoid reaction due to mixed malaria infection; report of a case. ( 18110690 )
1949

Variations for Mixed Malaria

Expression for Mixed Malaria

Search GEO for disease gene expression data for Mixed Malaria.

Pathways for Mixed Malaria

Pathways related to Mixed Malaria according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.33 RCAN1 XPO1

GO Terms for Mixed Malaria

Sources for Mixed Malaria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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