MCID: MXD027
MIFTS: 26

Mixed Type Thymoma

Categories: Cancer diseases, Immune diseases, Endocrine diseases

Aliases & Classifications for Mixed Type Thymoma

MalaCards integrated aliases for Mixed Type Thymoma:

Name: Mixed Type Thymoma 12 15
Thymoma, Mixed Type 12
Thymoma, Type Ab 73

Classifications:



External Ids:

Disease Ontology 12 DOID:3280
NCIt 50 C6885
SNOMED-CT 68 128709000
UMLS 73 C1266092

Summaries for Mixed Type Thymoma

MalaCards based summary : Mixed Type Thymoma, also known as thymoma, mixed type, is related to malignant type ab thymoma and spindle cell thymoma. An important gene associated with Mixed Type Thymoma is PAX8 (Paired Box 8), and among its related pathways/superpathways are Neuroscience and Central carbon metabolism in cancer. Related phenotypes are behavior/neurological and integument

Related Diseases for Mixed Type Thymoma

Diseases related to Mixed Type Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 malignant type ab thymoma 11.0
2 spindle cell thymoma 10.6 CD5 PAX8
3 water-clear cell adenoma 10.5 PAX8 SYP
4 cellular schwannoma 10.5 PAX8 S100B
5 primary hepatic neuroendocrine carcinoma 10.5 S100B SYP
6 chordoid meningioma 10.4 S100B SYP
7 hypoganglionosis 10.4 S100B SYP
8 dysembryoplastic neuroepithelial tumor 10.4 S100B SYP
9 rosette-forming glioneuronal tumor 10.4 S100B SYP
10 supratentorial primitive neuroectodermal tumor 10.4 S100B SYP
11 melanotic neuroectodermal tumor 10.4 S100B SYP
12 angiocentric glioma 10.4 S100B SYP
13 pineocytoma 10.4 S100B SYP
14 olfactory nerve neoplasm 10.4 AVP SYP
15 papillary ependymoma 10.4 S100B SYP
16 subependymal giant cell astrocytoma 10.4 S100B SYP
17 papilloma of choroid plexus 10.4 S100B SYP
18 central nervous system organ benign neoplasm 10.3 AVP SYP
19 sarcomatoid renal cell carcinoma 10.3 KIT PAX8
20 reticular perineurioma 10.3 KIT S100B
21 olfactory neuroblastoma 10.3 S100B SYP
22 cerebral primitive neuroectodermal tumor 10.3 S100B SYP
23 cranial nerve malignant neoplasm 10.3 AVP SYP
24 kidney benign neoplasm 10.3 KIT PAX8
25 ectopic cushing syndrome 10.3 S100B SYP
26 cervix small cell carcinoma 10.3 AVP SYP
27 rete testis neoplasm 10.3 KIT PAX8
28 optic nerve glioma 10.3 S100B SYP
29 amelanotic melanoma 10.3 KIT S100B
30 immune system organ benign neoplasm 10.3 CD5 SYP
31 perineurioma 10.3 KIT S100B
32 thymus lipoma 10.3 CD5 SYP
33 dental abscess 10.3 AVP KIT
34 thymic epithelial tumor 10.2 CD5 KIT
35 ganglioglioma 10.2 S100B SYP
36 embryonal sarcoma 10.2 KIT S100B
37 polymorphous low-grade adenocarcinoma 10.2 KIT S100B
38 atypical teratoid rhabdoid tumor 10.2 S100B SYP
39 ovarian brenner tumor 10.2 KIT PAX8
40 cutaneous ganglioneuroma 10.2 KIT SYP
41 ependymoma 10.1 S100B SYP
42 necrotizing sialometaplasia 10.1 CD5 KIT
43 chronic maxillary sinusitis 10.1 PDPN SYP
44 endometrial small cell carcinoma 10.1 KIT SYP
45 hemangioblastoma 10.1 S100B SYP
46 angiomyoma 10.1 KIT SYP
47 perivascular epithelioid cell tumor 10.1 KIT SYP
48 neurilemmoma 10.1 KIT S100B
49 hydromyelia 10.1 PTEN S100B
50 carney triad 10.1 KIT PDPN

Graphical network of the top 20 diseases related to Mixed Type Thymoma:



Diseases related to Mixed Type Thymoma

Symptoms & Phenotypes for Mixed Type Thymoma

MGI Mouse Phenotypes related to Mixed Type Thymoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.8 SYP AVP KIT PAX8 PDPN PTEN
2 integument MP:0010771 9.55 CD5 KIT PDPN PTEN S100B
3 nervous system MP:0003631 9.43 SYP AVP CD5 KIT PAX8 PTEN
4 normal MP:0002873 9.17 AVP CD5 KIT PAX8 PTEN S100B

Drugs & Therapeutics for Mixed Type Thymoma

Search Clinical Trials , NIH Clinical Center for Mixed Type Thymoma

Genetic Tests for Mixed Type Thymoma

Anatomical Context for Mixed Type Thymoma

Publications for Mixed Type Thymoma

Articles related to Mixed Type Thymoma:

# Title Authors Year
1
Multiple thymic squamous cell carcinomas associated with mixed type thymoma. ( 3688303 )
1987

Variations for Mixed Type Thymoma

Expression for Mixed Type Thymoma

Search GEO for disease gene expression data for Mixed Type Thymoma.

Pathways for Mixed Type Thymoma

Pathways related to Mixed Type Thymoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.67 AVP S100B SYP
2 10.97 KIT PTEN
3 10.35 CD5 KIT

GO Terms for Mixed Type Thymoma

Cellular components related to Mixed Type Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasmic side of plasma membrane GO:0009898 8.62 KIT PTEN

Biological processes related to Mixed Type Thymoma according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.69 AVP KIT PTEN
2 cell proliferation GO:0008283 9.67 CD5 PTEN S100B
3 negative regulation of apoptotic process GO:0043066 9.67 AVP KIT PDPN PTEN
4 regulation of cell shape GO:0008360 9.5 KIT PDPN S100B
5 learning or memory GO:0007611 9.48 PTEN S100B
6 social behavior GO:0035176 9.46 AVP PTEN
7 positive regulation of cell proliferation GO:0008284 9.46 AVP KIT PTEN S100B
8 long-term synaptic potentiation GO:0060291 9.43 PTEN S100B
9 regulation of neuronal synaptic plasticity GO:0048168 9.4 S100B SYP
10 water transport GO:0006833 9.26 AVP PDPN
11 maternal behavior GO:0042711 8.96 AVP PTEN
12 central nervous system development GO:0007417 8.8 PAX8 PTEN S100B

Sources for Mixed Type Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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