MCID: MXD027
MIFTS: 28

Mixed Type Thymoma

Categories: Cancer diseases, Endocrine diseases, Immune diseases

Aliases & Classifications for Mixed Type Thymoma

MalaCards integrated aliases for Mixed Type Thymoma:

Name: Mixed Type Thymoma 12 15
Thymoma, Mixed Type 12
Thymoma, Type Ab 74

Classifications:



External Ids:

Disease Ontology 12 DOID:3280
NCIt 51 C6885
UMLS 74 C1266092

Summaries for Mixed Type Thymoma

MalaCards based summary : Mixed Type Thymoma, also known as thymoma, mixed type, is related to malignant type ab thymoma and cellular schwannoma. An important gene associated with Mixed Type Thymoma is PAX8 (Paired Box 8), and among its related pathways/superpathways are Neuroscience and Central carbon metabolism in cancer. Affiliated tissues include thymus, colon and prostate, and related phenotypes are behavior/neurological and integument

Related Diseases for Mixed Type Thymoma

Diseases related to Mixed Type Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 92)
# Related Disease Score Top Affiliating Genes
1 malignant type ab thymoma 11.2
2 cellular schwannoma 10.2 PAX8 S100B
3 water-clear cell adenoma 10.2 PAX8 SYP
4 sensory organ benign neoplasm 10.2 PAX8 SYP
5 ependymoma 10.2 S100B SYP
6 primary hepatic neuroendocrine carcinoma 10.2 S100B SYP
7 chordoid meningioma 10.2 S100B SYP
8 hypoganglionosis 10.2 S100B SYP
9 dysembryoplastic neuroepithelial tumor 10.2 S100B SYP
10 rosette-forming glioneuronal tumor 10.2 S100B SYP
11 supratentorial primitive neuroectodermal tumor 10.2 S100B SYP
12 angiocentric glioma 10.2 S100B SYP
13 pineocytoma 10.2 S100B SYP
14 papillary ependymoma 10.2 S100B SYP
15 papilloma of choroid plexus 10.2 S100B SYP
16 malignant teratoma 10.2 AVP SYP
17 olfactory nerve neoplasm 10.2 AVP SYP
18 subependymal giant cell astrocytoma 10.2 S100B SYP
19 ectopic thymus 10.2 CD5 SYP
20 reticular perineurioma 10.2 KIT S100B
21 cerebral primitive neuroectodermal tumor 10.2 S100B SYP
22 perineurioma 10.2 KIT S100B
23 cervix small cell carcinoma 10.2 AVP SYP
24 sarcomatoid renal cell carcinoma 10.2 KIT PAX8
25 ectopic cushing syndrome 10.1 S100B SYP
26 olfactory neuroblastoma 10.1 S100B SYP
27 rete testis neoplasm 10.1 KIT PAX8
28 prostatic acinar adenocarcinoma 10.1 KIT PAX8
29 cranial nerve malignant neoplasm 10.1 AVP SYP
30 thymus lipoma 10.1 CD5 SYP
31 amelanotic melanoma 10.1 KIT S100B
32 optic nerve glioma 10.1 S100B SYP
33 immune system organ benign neoplasm 10.1 CD5 SYP
34 tracheoesophageal fistula 10.1 S100B SYP
35 dental abscess 10.1 AVP KIT
36 thymic epithelial tumor 10.1 CD5 KIT
37 ganglioglioma 10.1 S100B SYP
38 embryonal sarcoma 10.1 KIT S100B
39 lymphoepithelioma-like thymic carcinoma 10.1 CD5 KIT
40 polymorphous low-grade adenocarcinoma 10.1 KIT S100B
41 ovarian brenner tumor 10.1 KIT PAX8
42 chronic maxillary sinusitis 10.1 PDPN SYP
43 hemangioblastoma 10.1 S100B SYP
44 cutaneous ganglioneuroma 10.1 KIT SYP
45 necrotizing sialometaplasia 10.1 CD5 KIT
46 endometrial small cell carcinoma 10.1 KIT SYP
47 teratoma 10.1 KIT SYP
48 neurilemmoma 10.0 KIT S100B
49 angiomyoma 10.0 KIT SYP
50 perivascular epithelioid cell tumor 10.0 KIT SYP

Graphical network of the top 20 diseases related to Mixed Type Thymoma:



Diseases related to Mixed Type Thymoma

Symptoms & Phenotypes for Mixed Type Thymoma

MGI Mouse Phenotypes related to Mixed Type Thymoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.8 AVP KIT PAX8 PDPN PTEN S100B
2 integument MP:0010771 9.55 CD5 KIT PDPN PTEN S100B
3 nervous system MP:0003631 9.43 AVP CD5 KIT PAX8 PTEN SYP
4 normal MP:0002873 9.17 AVP CD5 KIT PAX8 PTEN S100B

Drugs & Therapeutics for Mixed Type Thymoma

Search Clinical Trials , NIH Clinical Center for Mixed Type Thymoma

Genetic Tests for Mixed Type Thymoma

Anatomical Context for Mixed Type Thymoma

MalaCards organs/tissues related to Mixed Type Thymoma:

42
Thymus, Colon, Prostate, Lung, Cervix, Testis

Publications for Mixed Type Thymoma

Articles related to Mixed Type Thymoma:

# Title Authors Year
1
Multiple thymic squamous cell carcinomas associated with mixed type thymoma. ( 3688303 )
1987

Variations for Mixed Type Thymoma

Expression for Mixed Type Thymoma

Search GEO for disease gene expression data for Mixed Type Thymoma.

Pathways for Mixed Type Thymoma

Pathways related to Mixed Type Thymoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.67 AVP S100B SYP
2 10.97 KIT PTEN
3 10.35 CD5 KIT

GO Terms for Mixed Type Thymoma

Cellular components related to Mixed Type Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasmic side of plasma membrane GO:0009898 8.62 KIT PTEN

Biological processes related to Mixed Type Thymoma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 cell proliferation GO:0008283 9.67 CD5 PTEN S100B
2 negative regulation of apoptotic process GO:0043066 9.58 AVP PDPN PTEN
3 positive regulation of cell proliferation GO:0008284 9.56 AVP KIT PTEN S100B
4 learning or memory GO:0007611 9.48 PTEN S100B
5 social behavior GO:0035176 9.46 AVP PTEN
6 long-term synaptic potentiation GO:0060291 9.43 PTEN S100B
7 regulation of neuronal synaptic plasticity GO:0048168 9.37 S100B SYP
8 regulation of cell shape GO:0008360 9.33 KIT PDPN S100B
9 water transport GO:0006833 9.32 AVP PDPN
10 maternal behavior GO:0042711 8.96 AVP PTEN
11 central nervous system development GO:0007417 8.8 PAX8 PTEN S100B

Sources for Mixed Type Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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