MCID: MXD027
MIFTS: 19

Mixed Type Thymoma

Categories: Cancer diseases, Endocrine diseases, Immune diseases

Aliases & Classifications for Mixed Type Thymoma

MalaCards integrated aliases for Mixed Type Thymoma:

Name: Mixed Type Thymoma 12 15
Thymoma, Mixed Type 12
Thymoma, Type Ab 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3280
NCIt 49 C6885
UMLS 71 C1266092

Summaries for Mixed Type Thymoma

MalaCards based summary : Mixed Type Thymoma, also known as thymoma, mixed type, is related to malignant type ab thymoma and thymoma, familial. An important gene associated with Mixed Type Thymoma is ALPG (Alkaline Phosphatase, Germ Cell). Affiliated tissues include lung, and related phenotype is normal.

Related Diseases for Mixed Type Thymoma

Diseases related to Mixed Type Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 malignant type ab thymoma 11.4
2 thymoma, familial 9.9
3 thymoma 9.9
4 thymic carcinoma 9.9
5 subleukemic leukemia 9.7 S100B AVP
6 intracranial berry aneurysm 9.7 S100B AVP
7 combined thymoma 9.6 PDPN PAX8
8 seminoma 9.5 PDPN ALPG
9 neurofibroma 9.5 S100B PDPN
10 renal cell carcinoma, papillary, 1 9.4 PDPN PAX8
11 cardiac arrest 9.4 S100B AVP
12 hemangioblastoma 9.1 S100B PDPN PAX8

Graphical network of the top 20 diseases related to Mixed Type Thymoma:



Diseases related to Mixed Type Thymoma

Symptoms & Phenotypes for Mixed Type Thymoma

MGI Mouse Phenotypes related to Mixed Type Thymoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 normal MP:0002873 8.92 ALPG AVP PAX8 S100B

Drugs & Therapeutics for Mixed Type Thymoma

Search Clinical Trials , NIH Clinical Center for Mixed Type Thymoma

Genetic Tests for Mixed Type Thymoma

Anatomical Context for Mixed Type Thymoma

MalaCards organs/tissues related to Mixed Type Thymoma:

40
Lung

Publications for Mixed Type Thymoma

Articles related to Mixed Type Thymoma:

(show all 28)
# Title Authors PMID Year
1
Ectopic thymoma: report of 2 cases and review of the literature. 61
31933830 2019
2
Prognostic value of immunohistochemical markers in malignant thymic epithelial tumors. 61
27747012 2016
3
Concurrent thymoma, thymic carcinoma, and T lymphoblastic leukemia/lymphoma in an anterior mediastinal mass. 61
26150396 2015
4
Establishment and characterization of a novel cell line derived from thymoma with myasthenia gravis patients. 61
26273358 2015
5
Successful Diagnosis of a Thymoma by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: A Report of Two Cases. 61
26521902 2015
6
Associated immunological disorders and cellular immune dysfunction in thymoma: a study of 87 cases from Thailand. 61
23229679 2013
7
A case of middle mediastinal thymoma. 61
22610165 2012
8
18F-fluorodeoxyglucose and 11C-acetate positron emission tomography are useful modalities for diagnosing the histologic type of thymoma. 61
19326456 2009
9
[Recurrence of thymoma as pleural dissemination 23-years after surgery]. 61
19195191 2009
10
[Long-term prognostic analysis of surgical treatment of the thymoma-associated myasthenia gravis]. 61
19668149 2009
11
Recurrent myasthenia gravis due to a pleural implant 3 years after radical thymectomy. 61
18573446 2008
12
Malignant thymoma associated with myasthenia gravis, Graves' disease, and SIADH. 61
18520111 2008
13
Ring chromosome 6 may represent a cytogenetic subgroup in benign thymoma. 61
12377419 2002
14
[A case of thymoma with pure red cell aplasia]. 61
11761906 2001
15
Minimally invasive thymoma with extensive intravascular growth. 61
10721946 1999
16
Dermatomyositis associated with invasive thymoma. 61
10225672 1999
17
Thymic lymphoepithelioma-like carcinoma associated with thymoma in a patient with ocular myasthenia. 61
9636966 1998
18
[A case of thymic cyst and thymoma with myasthenia gravis]. 61
9330525 1997
19
Preoperative intra-arterial infusion chemotherapy for invasive thymoma: a case report. 61
9001356 1996
20
A rare case of typical carcinoid of the lung coincident with thymoma. 61
7967108 1994
21
[A case of thymoma showing extensive necrosis]. 61
8409618 1993
22
Thymoma: a study of the pathologic classification of 71 cases with evaluation of the Muller-Hermelink system. 61
8319955 1993
23
[A case of thymoma with thymic cyst]. 61
1431407 1992
24
Adenine nucleotide content of thymoma-derived lymphocytes. 61
1519315 1992
25
[Two cases of post-thymectomy myasthenia gravis]. 61
1402200 1992
26
An immunohistochemical study of thymic epithelial tumors. III. The distribution of interdigitating reticulum cells and S-100 beta-positive small lymphocytes. 61
2252104 1990
27
Multiple clonal chromosome aberrations in two thymomas. 61
2766255 1989
28
Multiple thymic squamous cell carcinomas associated with mixed type thymoma. 61
3688303 1987

Variations for Mixed Type Thymoma

Expression for Mixed Type Thymoma

Search GEO for disease gene expression data for Mixed Type Thymoma.

Pathways for Mixed Type Thymoma

GO Terms for Mixed Type Thymoma

Cellular components related to Mixed Type Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ruffle GO:0001726 8.62 S100B PDPN

Biological processes related to Mixed Type Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cell shape GO:0008360 9.16 S100B PDPN
2 central nervous system development GO:0007417 8.96 S100B PAX8
3 water transport GO:0006833 8.62 PDPN AVP

Molecular functions related to Mixed Type Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 8.8 S100B PDPN AVP

Sources for Mixed Type Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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