MCID: MBT001
MIFTS: 25

Mobitz Type Ii Atrioventricular Block

Categories: Cardiovascular diseases

Aliases & Classifications for Mobitz Type Ii Atrioventricular Block

MalaCards integrated aliases for Mobitz Type Ii Atrioventricular Block:

Name: Mobitz Type Ii Atrioventricular Block 12 15 71
Mobitz Ii Atrioventricular Block 12
Mobitz Ii Atrioventricular Block 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11312
ICD9CM 34 426.12
NCIt 49 C62018
SNOMED-CT 67 28189009
UMLS 71 C0155700

Summaries for Mobitz Type Ii Atrioventricular Block

MalaCards based summary : Mobitz Type Ii Atrioventricular Block, also known as mobitz ii atrioventricular block, is related to atrioventricular block and right bundle branch block. An important gene associated with Mobitz Type Ii Atrioventricular Block is CA5B (Carbonic Anhydrase 5B), and among its related pathways/superpathways is Cobalamin (Cbl, vitamin B12) transport and metabolism. Affiliated tissues include heart, lung and uterus.

Related Diseases for Mobitz Type Ii Atrioventricular Block

Diseases related to Mobitz Type Ii Atrioventricular Block via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 atrioventricular block 31.2 CA5B ACE
2 right bundle branch block 30.1 CA5B ACE
3 progressive familial heart block, type ia 10.2
4 cardiac arrhythmia 10.2
5 stroke, ischemic 10.2
6 progressive familial heart block, type ib 10.2
7 thrombocytopenia 10.2
8 ischemia 10.2
9 systolic heart failure 10.2
10 syncope 10.2
11 serotonin syndrome 10.2
12 second-degree atrioventricular block 10.2
13 pulmonary valve insufficiency 10.0 CA5B ACE
14 third-degree atrioventricular block 10.0 CA5B ACE
15 left bundle branch hemiblock 10.0 CA5B ACE
16 transcobalamin ii deficiency 10.0 TCN2 TCN1
17 tricuspid valve insufficiency 9.9 CA5B ACE
18 tricuspid valve disease 9.9 CA5B ACE
19 vitamin metabolic disorder 9.9 TCN2 TCN1
20 aortic valve insufficiency 9.9 CA5B ACE
21 pernicious anemia 9.9 TCN2 TCN1
22 vitamin b12 deficiency 9.8 TCN2 TCN1
23 heart conduction disease 9.8 CA5B ACE
24 megaloblastic anemia 9.7 TCN2 TCN1
25 pancytopenia 9.5 TCN2 ACE

Comorbidity relations with Mobitz Type Ii Atrioventricular Block via Phenotypic Disease Network (PDN): (show all 11)


Acute Cystitis Aortic Valve Disease 1
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Heart Disease Hypertension, Essential
Intermediate Coronary Syndrome Mitral Valve Disease
Right Bundle Branch Block Sinoatrial Node Disease
Third-Degree Atrioventricular Block

Graphical network of the top 20 diseases related to Mobitz Type Ii Atrioventricular Block:



Diseases related to Mobitz Type Ii Atrioventricular Block

Symptoms & Phenotypes for Mobitz Type Ii Atrioventricular Block

Drugs & Therapeutics for Mobitz Type Ii Atrioventricular Block

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Safety and Feasibility of the Injectable BL-1040 Implant Unknown status NCT00557531 Phase 1, Phase 2

Search NIH Clinical Center for Mobitz Type Ii Atrioventricular Block

Genetic Tests for Mobitz Type Ii Atrioventricular Block

Anatomical Context for Mobitz Type Ii Atrioventricular Block

MalaCards organs/tissues related to Mobitz Type Ii Atrioventricular Block:

40
Heart, Lung, Uterus

Publications for Mobitz Type Ii Atrioventricular Block

Articles related to Mobitz Type Ii Atrioventricular Block:

(show all 41)
# Title Authors PMID Year
1
Routine Continuous Electrocardiographic Monitoring Following Percutaneous Coronary Interventions. 61
31884835 2020
2
Left bundle branch pacing from distal His-bundle region by tricuspid valve annulus angiography. 61
31544273 2019
3
A case report positive for synthetic cannabinoids: are cardiovascular effects related to their protracted use? 61
31683096 2019
4
How much can synthetic cannabinoid damage the heart? A case of cardiogenic shock following resistant ventricular fibrillation after synthetic cannabinoid use. 61
29479764 2018
5
Intraoperative Device Closure of Isolated Ventricular Septal Defects: Experience on 1,090 Cases. 61
29596821 2018
6
Mobitz Type II Atrioventricular Block following Tramadol and Fentanyl in a Patient with Acute Coronary Syndrome and Systolic Heart Failure. 61
29184615 2017
7
Conduction Disorders After Sutureless Aortic Valve Replacement. 61
27717423 2017
8
A Mobitz type II atrioventricular block in multicentric ischemic stroke. 61
28154620 2016
9
A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments. 61
26536992 2015
10
Intraarrest rhythms and rhythm conversion in asphyxial cardiac arrest. 61
25903291 2015
11
Chest pain with minimal activities and flexion of trunk: a rare case of angina. 61
23442815 2015
12
Closure of perimembranous ventricular septal defects with intraoperative device technique: another safe alternative to surgical repair. 61
22684414 2013
13
Mobitz Type II Atrioventricular Block Followed by Remifentanil in a Patient with Severe Aortic Stenosis. 61
23662214 2013
14
Severe tricuspid regurgitation and atrioventicular block caused by blunt thoracic trauma in an elderly woman. 61
20851553 2012
15
Dual-chamber pacemaker malfunction mimicking atrial capture by the ventricular electrode. 61
21478130 2011
16
[Mobitz type II block during one-lung ventilation]. 61
20229756 2010
17
Alternating bundle branch block together with alternation of PR intervals: advanced Mobitz II atrioventricular block. 61
20495518 2010
18
Kikuchi-Fujimoto disease manifesting as recurrent thrombocytopenia and Mobitz type II atrioventricular block in a 7-year-old girl: a case report and analysis of 138 Chinese childhood Kikuchi-Fujimoto cases with 10 years of follow-up in 97 patients. 61
17931395 2007
19
Peri-operative atrioventricular block as a result of chemotherapy with epirubicin and paclitaxel. 61
17223814 2007
20
Persistent left-sided superior vena cava--a pacing challenge. 61
18030627 2007
21
Effect of biventricular pacing on left ventricular outflow tract pressure gradient in a patient with hypertrophic cardiomyopathy and normal interventricular conduction. 61
16533259 2006
22
A case of alternating bundle branch block in combination with intra-Hisian block. 61
16157965 2005
23
Possible complications of subclavian crush syndrome. 61
25696461 2005
24
Octreotide-induced bradycardia and heart block during surgical resection of a carcinoid tumor. 61
14742361 2004
25
[Definitions of second degree atrioventricular block. An exercise in logic in clinical electrocardiography]. 61
11107481 2000
26
Supernormal conduction in a case of Mobitz type II atrioventricular block. 61
9533380 1998
27
[Case report of coronary artery bypass performed on a patient implanted with a single-lead atrial triggered ventricular VDD pacemaker]. 61
9071145 1997
28
[Mobitz type II atrioventricular block as a side effect of pentoxifylline]. 61
8926709 1996
29
Failure of the circulatory system limits exercise performance in patients with systemic sclerosis. 61
8213874 1993
30
Functional dissociation of cellular activation as a mechanism of Mobitz type II atrioventricular block. 61
8462160 1993
31
Cough syncope presenting as Mobitz type II atrioventricular block--an electrophysiologic correlation. 61
2436170 1987
32
A simplified method to predict occurrence of complete heart block during acute myocardial infarction. 61
3717016 1986
33
Cardiac arrhythmias in the elderly: clinical aspects. 61
2423243 1986
34
Reentrant tachycardia associated with atrial synchronous pacing. Report of a case with intact ventriculoatrial conduction. 61
6887977 1983
35
The "holiday heart": electrophysiologic studies of alcohol effects in alcoholics. 61
6824246 1983
36
Clinical and electrophysiologic findings in patients with paroxysmal slowing of the sinus rate and apparent Mobitz type II atrioventricular block. 61
668079 1978
37
[A case of Mobitz type II atrioventricular block diagnosed in uterus]. 61
747830 1978
38
Mobitz II atrioventricular block due to infra-Hisian block and bundle branch extrasystoles. 61
57202 1976
39
Tachycardia-dependent and bradycardia-dependent Mobitz type II atrioventricular block within the bundle of His. 61
4829374 1974
40
Mobitz type II atrioventricular block in a newborn. 61
5045362 1972
41
Mobitz type II atrioventricular block in children. 61
5132309 1971

Variations for Mobitz Type Ii Atrioventricular Block

Expression for Mobitz Type Ii Atrioventricular Block

Search GEO for disease gene expression data for Mobitz Type Ii Atrioventricular Block.

Pathways for Mobitz Type Ii Atrioventricular Block

Pathways related to Mobitz Type Ii Atrioventricular Block according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.95 TCN2 TCN1

GO Terms for Mobitz Type Ii Atrioventricular Block

Cellular components related to Mobitz Type Ii Atrioventricular Block according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 8.92 TCN2 TCN1 PROM1 ACE

Biological processes related to Mobitz Type Ii Atrioventricular Block according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cobalamin metabolic process GO:0009235 9.16 TCN2 TCN1
2 cobalamin transport GO:0015889 8.96 TCN2 TCN1
3 cobalt ion transport GO:0006824 8.62 TCN2 TCN1

Molecular functions related to Mobitz Type Ii Atrioventricular Block according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cobalamin binding GO:0031419 8.62 TCN2 TCN1

Sources for Mobitz Type Ii Atrioventricular Block

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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