MCID: MNC003
MIFTS: 16

Monckeberg Arteriosclerosis

Categories: Cardiovascular diseases

Aliases & Classifications for Monckeberg Arteriosclerosis

MalaCards integrated aliases for Monckeberg Arteriosclerosis:

Name: Monckeberg Arteriosclerosis 12 15
Monckeberg Medial Calcific Sclerosis 71

Classifications:



External Ids:

Disease Ontology 12 DOID:5161
UMLS 71 C0887866

Summaries for Monckeberg Arteriosclerosis

MalaCards based summary : Monckeberg Arteriosclerosis, also known as monckeberg medial calcific sclerosis, is related to arteriosclerosis and end stage renal failure. An important gene associated with Monckeberg Arteriosclerosis is RARRES2 (Retinoic Acid Receptor Responder 2), and among its related pathways/superpathways is Cell adhesion molecules (CAMs). The drugs Calcium and Calcium, Dietary have been mentioned in the context of this disorder. Related phenotypes are hematopoietic system and immune system

Related Diseases for Monckeberg Arteriosclerosis

Diseases related to Monckeberg Arteriosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 arteriosclerosis 10.4
2 end stage renal failure 10.3
3 peripheral vascular disease 9.6 SELE RARRES2
4 demyelinating disease 9.4 RARRES2 CMKLR1

Symptoms & Phenotypes for Monckeberg Arteriosclerosis

MGI Mouse Phenotypes related to Monckeberg Arteriosclerosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.46 CMKLR1 RARRES2 SELE VSIR
2 immune system MP:0005387 9.26 CMKLR1 RARRES2 SELE VSIR
3 respiratory system MP:0005388 8.8 CMKLR1 SELE VSIR

Drugs & Therapeutics for Monckeberg Arteriosclerosis

Drugs for Monckeberg Arteriosclerosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Calcium Approved, Nutraceutical 7440-70-2 271
2 Calcium, Dietary

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of the Mechanisms of the Arterial Calcification of the Members Subordinates in the Diabetes (Implication of the System RANK / RANKL / OSTEOPROTEGERINE) Active, not recruiting NCT02431234
2 Morphological, Biomechanical and Functional Properties of the Arterial Wall of Athletes: Impact and Consequences of Mechanical Stress on the Cardiovascular Adaptations of Peripheral Arterial Calcifications Terminated NCT01577576

Search NIH Clinical Center for Monckeberg Arteriosclerosis

Genetic Tests for Monckeberg Arteriosclerosis

Anatomical Context for Monckeberg Arteriosclerosis

Publications for Monckeberg Arteriosclerosis

Articles related to Monckeberg Arteriosclerosis:

# Title Authors PMID Year
1
Monckeberg Arteriosclerosis: A Telltale Sign. 61
28499804 2017
2
Monckeberg medial calcific sclerosis mimicking malignant calcification pattern at mammography. 61
15790721 2005
3
Renal enlargement and Monckeberg arteriosclerosis following injections of hematoporphyrin. 61
14012351 1963

Variations for Monckeberg Arteriosclerosis

Expression for Monckeberg Arteriosclerosis

Search GEO for disease gene expression data for Monckeberg Arteriosclerosis.

Pathways for Monckeberg Arteriosclerosis

Pathways related to Monckeberg Arteriosclerosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.79 VSIR SELE

GO Terms for Monckeberg Arteriosclerosis

Biological processes related to Monckeberg Arteriosclerosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemotaxis GO:0006935 9.26 RARRES2 CMKLR1
2 positive regulation of fat cell differentiation GO:0045600 9.16 RARRES2 CMKLR1
3 inflammatory response GO:0006954 9.13 SELE RARRES2 CMKLR1
4 positive regulation of macrophage chemotaxis GO:0010759 8.62 RARRES2 CMKLR1

Sources for Monckeberg Arteriosclerosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....